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    HEMATOLOGICAL ANALYZER, METHOD FOR ANALYZING BODY FLUID AND COMPUTER PROGRAM PRODUCT
    4.
    发明申请
    HEMATOLOGICAL ANALYZER, METHOD FOR ANALYZING BODY FLUID AND COMPUTER PROGRAM PRODUCT 审中-公开
    血液分析仪，分析体液和计算机程序产品的方法

    公开(公告)号：US20140356903A1

    公开(公告)日：2014-12-04

    申请号：US14461469

    申请日：2014-08-18

    申请人： SYSMEX CORPORATION

    发明人： Takaaki NAGAI ,  Noriyuki NARISADA ,  Hans KALKMAN

    IPC分类号： G01N33/50 ,  G01N33/80 ,  G01N33/72

    CPC分类号： G01N33/5094 ,  G01N15/12 ,  G01N15/1459 ,  G01N33/721 ,  G01N33/80 ,  G01N2015/0073 ,  G01N2015/0076 ,  G01N2015/008 ,  G01N2015/1402 ,  G01N2015/1486

    摘要： A hematological analyzer for measuring blood, sets a body fluid measurement mode; receives a measurement start instruction; irradiates a measurement sample with light and obtains optical information from cells contained in the measurement sample; and classifies at least white blood cells and nucleated cells other than white blood cells contained in the measurement sample, and counts the white blood cells and nucleated cells other than white blood cells based on the optical information obtained from the cells in the measurement sample prepared from a body fluid sample and white blood cell measuring reagent when the body fluid measurement mode has been set and the measurement start instruction has been selected, is disclosed. A method for analyzing body fluid and a computer program product are also disclosed.

    摘要翻译： 用于测量血液的血液分析仪，设定体液测量模式; 接收测量开始指令; 用光照射测量样品，并从测量样品中包含的细胞获得光学信息; 并且至少对除了测量样品中包含的白细胞以外的白细胞和有核细胞进行分类，并且基于从由从细胞中制备的测量样品中的细胞获得的光学信息对白血细胞以外的白细胞和有核细胞进行计数 公开了当已经设置体液测量模式并且已经选择测量开始指令时的体液样品和白细胞测量试剂。 还公开了一种用于分析体液的方法和计算机程序产品。

    Method and apparatus for detecting and counting platelets individually and in aggregate clumps
    5.
    发明授权
    Method and apparatus for detecting and counting platelets individually and in aggregate clumps 有权
    用于单独和聚集团中血小板检测和计数的方法和装置

    公开(公告)号：US08310659B2

    公开(公告)日：2012-11-13

    申请号：US13323438

    申请日：2011-12-12

    申请人： Stephen C. Wardlaw ,  Robert A. Levine ,  Niten V. Lalpuria

    发明人： Stephen C. Wardlaw ,  Robert A. Levine ,  Niten V. Lalpuria

    IPC分类号： G01N33/48

    CPC分类号： G01N33/49 ,  G01N15/147 ,  G01N15/1475 ,  G01N2015/0076 ,  G01N2015/008 ,  G01N2015/0084 ,  G01N2015/0092 ,  G01N2015/1486

    摘要： A method for enumerating platelets within a blood sample is provided. The method includes the steps of: 1) depositing the sample into a sample container having an analysis chamber adapted to quiescently hold the sample for analysis, and an amount of colorant that platelets absorb and which fluoresces upon exposure to one or more predetermined first wavelengths of light; 2) imaging at least a portion of the sample disposed in the analysis chamber, including producing image signals indicative of fluorescent emissions from the platelets illuminated by first wavelengths of light; 3) identifying the platelets using the image signals; and 4) enumerating individual platelets and clumped platelets within the sample using one or more of fluorescent emissions, area, shape, and granularity.

    摘要翻译： 提供了一种用于列举血液样品中的血小板的方法。 该方法包括以下步骤：1）将样品沉积到具有分析室的样品容器中，所述分析室适于静态保持样品进行分析，以及一定量的着色剂，血小板被吸收并且在暴露于一个或多个预定的第一波长 光; 2）对设置在分析室中的样品的至少一部分进行成像，包括产生指示由第一波长的光照射的血小板的荧光发射的图像信号; 3）使用图像信号识别血小板; 和4）使用荧光发射，面积，形状和粒度中的一种或多种来列举样品中的各个血小板和聚集的血小板。

    Analyzer
    6.
    发明授权
    Analyzer 有权
    分析仪

    公开(公告)号：US07981662B2

    公开(公告)日：2011-07-19

    申请号：US12079650

    申请日：2008-03-28

    申请人： Kunio Ueno ,  Seiichiro Tabata

    发明人： Kunio Ueno ,  Seiichiro Tabata

    IPC分类号： C12M1/34 ,  G01N21/00 ,  G01N31/00 ,  G01N33/48 ,  G01N1/00

    CPC分类号： G01N15/14 ,  G01N15/1427 ,  G01N15/1429 ,  G01N15/1459 ,  G01N2015/0076 ,  G01N2015/008 ,  G01N2015/0084 ,  G01N2015/1006 ,  G01N2015/1477 ,  G01N2015/1486 ,  G01N2015/1488 ,  G01N2015/1493

    摘要： A sample analyzer for analyzing a biological sample is disclosed that comprising: a measurement specimen preparation section for preparing a measurement specimen by using a reagent and the biological sample; a irradiator for irradiating the measurement specimen with a light; a first light receiving section for receiving a light from the measurement specimen and converting the received light into an electrical signal; a analysis section for analyzing the measurement specimen based on the electrical signal output by the first light receiving section; and a selection section for selecting an intensity of light to be irradiated by the irradiator, wherein the irradiator is configured to irradiate with a light of an intensity corresponding to the light intensity selected by the selection section.

    摘要翻译： 公开了一种用于分析生物样品的样本分析器，其包括：用于通过使用试剂和所述生物样品来制备测量样本的测量样本制备部分; 用于用光照射测量样品的辐射器; 第一光接收部分，用于接收来自测量样本的光并将接收的光转换成电信号; 分析部，其基于由所述第一光接收部输出的电信号来分析所述测量样本; 以及选择部，用于选择由照射器照射的光的强度，其中，所述照射器被配置为用与所述选择部所选择的光强度相对应的强度的光照射。

    Particle analyzer and particle analyzing method
    7.
    发明授权
    Particle analyzer and particle analyzing method 有权
    粒子分析仪和粒子分析方法

    公开(公告)号：US07936456B2

    公开(公告)日：2011-05-03

    申请号：US12022658

    申请日：2008-01-30

    申请人： Noriyuki Narisada

    发明人： Noriyuki Narisada

    IPC分类号： G01N1/00 ,  G01N21/66

    CPC分类号： G01N15/1459 ,  G01N15/12 ,  G01N35/00594 ,  G01N2015/0073 ,  G01N2015/0076 ,  G01N2015/008 ,  G01N2015/1486

    摘要： The present invention is to present a particle analyzer that is capable of classifying and counting particles contained in a sample more accurately. The blood analyzer 1 includes: measuring unit 2 for obtaining a plurality of characteristic information of each of particles contained in a sample by measuring a measurement sample prepared from the sample; data processing unit 3 for obtaining a particle number of a specific kind of particles and each particle number of a plural kinds of particles different from the specific kind of particles, and determining a target kind of particles, whose particle number is corrected, from the plural kinds of particles, based on information obtained by the measuring unit 2, and correcting a particle number of the target kind of particles by using the particle number of the specific kind of particles.

    摘要翻译： 本发明是提供一种能够更准确地分析和计数包含在样品中的颗粒的粒子分析仪。 血液分析装置1包括：测量单元2，用于通过测量从样品制备的测量样品来获得样品中包含的每个颗粒的多个特征信息; 数据处理单元3，用于获得特定种类的颗粒的颗粒数和与特定种类的颗粒不同的多种颗粒的每个颗粒数，并且从多个颗粒中确定粒子数被校正的颗粒的目标种类 基于由测量单元2获得的信息，通过使用特定种类的颗粒的粒子数来校正目标种类的颗粒数。

    Method and apparatus for detecting and counting platelets individually and in aggregate clumps
    8.
    发明授权
    Method and apparatus for detecting and counting platelets individually and in aggregate clumps 有权
    用于单独和聚集团中血小板检测和计数的方法和装置

    公开(公告)号：US07929121B2

    公开(公告)日：2011-04-19

    申请号：US12408500

    申请日：2009-03-20

    申请人： Stephen C. Wardlaw ,  Robert A. Levine ,  Niten V. Lalpuria

    发明人： Stephen C. Wardlaw ,  Robert A. Levine ,  Niten V. Lalpuria

    IPC分类号： G01N33/48

    CPC分类号： G01N33/49 ,  G01N15/147 ,  G01N15/1475 ,  G01N2015/0076 ,  G01N2015/008 ,  G01N2015/0084 ,  G01N2015/0092 ,  G01N2015/1486

    摘要： A method for enumerating platelets within a blood sample is provided. The method includes the steps of: 1) depositing the sample into an analysis chamber adapted to quiescently hold the sample for analysis, the chamber defined by a first panel and a second panel, both of which panels are transparent; 2) admixing a colorant with the sample, which colorant is operative to cause the platelets to fluoresce upon exposure to one or more predetermined first wavelengths of light; 3) illuminating at least a portion of the sample containing the platelets at the first wavelengths; 4) imaging the sample, including producing image signals indicative of fluorescent emissions from the platelets, which fluorescent emissions have an intensity; 5) identifying the platelets by their fluorescent emissions, using the image signals; 6) determining an average fluorescent emission intensity value for the individual platelets identified within the sample; 7) identifying clumps of platelets within the sample using one or more of their fluorescent emissions, area, shape, and granularity; and 8) enumerating platelets within each platelet clump using the average fluorescent emission intensity value determined for the individual platelets within the sample.

    摘要翻译： 提供了一种用于列举血液样品中的血小板的方法。 该方法包括以下步骤：1）将样品沉积到适于静态保持样品进行分析的分析室中，所述室由第一面板和第二面板限定，两个面板都是透明的; 2）将着色剂与所述样品混合，所述着色剂在暴露于一个或多个预定的第一波长的光时会使血小板发荧光; 3）以第一波长照射含有血小板的样品的至少一部分; 4）对样品进行成像，包括产生指示来自血小板的荧光发射的图像信号，该荧光发射具有强度; 5）使用图像信号通过荧光发射识别血小板; 6）确定样品内识别的各个血小板的平均荧光发射强度值; 7）使用其荧光发射，面积，形状和粒度中的一种或多种来鉴定样品中的血小板团块; 和8）使用为样品中的各个血小板确定的平均荧光发射强度值来列举每个血小板聚集体内的血小板。

    Methods of detection of iron deficiency and hemochromatosis
    9.
    发明申请
    Methods of detection of iron deficiency and hemochromatosis 有权
    检测铁缺乏症和血色素沉着症的方法

    公开(公告)号：US20070072300A1

    公开(公告)日：2007-03-29

    申请号：US11524682

    申请日：2006-09-21

    申请人： Ramon Simon-Lopez

    发明人： Ramon Simon-Lopez

    IPC分类号： G01N35/00

    CPC分类号： G01N33/90 ,  G01N15/12 ,  G01N33/721 ,  G01N2015/0069 ,  G01N2015/0076 ,  G01N2015/008 ,  G01N2015/0084 ,  G01N2015/1062 ,  G01N2015/1093 ,  Y10T436/11

    摘要： New diagnostic parameters or indexes for detection of absolute iron deficiency, latent iron deficiency, functional iron deficiency, or latent functional iron deficiency have been disclosed. The parameters include a RBC size factor, RSf1 defined by the formula of (MCV×MRV)1/2, or RSf2 defined by the formula of (MCV×MRV)/100, a volume-hemoglobin factor (VHf) defined by the formula of (MCV×Hgb)/100, and a volume-hemoglobin/distribution factor (VHDWf) defined by the formula of (MCV×Hgb)/(RDW×10). Further disclosed are the methods of using these parameters for detection of absolute iron deficiency, latent iron deficiency, functional iron deficiency, or latent functional iron deficiency. Also disclosed is a method of using RSf for detection of hemochromatosis.

    摘要翻译： 已经公开了用于检测绝对铁缺乏，潜在铁缺乏，功能性铁缺乏或潜在功能性铁缺乏症的新的诊断参数或指标。 这些参数包括由式（MCVxMRV）或由式（5）定义的RSf 2 2定义的RBC大小因子RSf 1 < 的（MCVxMRV）/ 100，由式（MCVxHgb）/ 100定义的体积血红蛋白因子（VHf）和由式（MCVxHgb）/（RDWx10）定义的体积 - 血红蛋白/分布因子（VHDWf）。 还公开了使用这些参数来检测绝对铁缺乏，潜铁缺乏，功能性铁缺乏或潜在功能缺铁的方法。 还公开了使用RSf检测血色素沉着症的方法。