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    Onboard device and method for analyzing fluid in a heat engine
    1.
    发明授权
    Onboard device and method for analyzing fluid in a heat engine 有权
    用于分析热机中流体的车载装置和方法

    公开(公告)号：US09562850B2

    公开(公告)日：2017-02-07

    申请号：US14648855

    申请日：2013-12-04

    Applicant: SP3H

    Inventor： Sylvain Oberti ,  Johan Fournel

    IPC: G01N21/3577 ,  G01N21/3504 ,  G01N21/27 ,  G01N21/31

    CPC classification number: G01N21/3577 ,  G01N21/274 ,  G01N21/3504 ,  G01N2021/3181 ,  G01N2201/062 ,  G01N2201/0624 ,  G01N2201/121 ,  G01N2201/1211 ,  G01N2201/124 ,  G01N2201/1242 ,  G01N2201/1247 ,  G01N2201/127 ,  G01N2201/12723

    Abstract: A method for controlling a spectrometer for analyzing a product includes steps of: acquiring a measurement representative of the operation of a light source, determining, depending on the measurement, a value of supply current of the light source, and/or a value of integration time of light-sensitive cells of a sensor, disposed on a route of a light beam emitted by the light source and having interacted with a product to be analyzed, and if the integration time and/or supply current value is between threshold values, supplying the light source with a supply current corresponding to the determined supply current value, adjusting the integration time of a light-sensitive cell to the determined integration time value, and acquiring light intensity measurements supplied by the sensor, enabling a spectrum to be formed.

    Abstract translation: 一种用于控制用于分析产品的光谱仪的方法包括以下步骤：获取代表光源的操作的测量，根据测量确定光源的电源电流的值和/或积分值 传感器的感光单元的时间设置在由光源发射的光束的路径上并且与待分析的产品相互作用，并且如果积分时间和/或电源电流值在阈值之间，则提供 所述光源具有与所确定的电源电流值相对应的电源电流，将感光单元的积分时间调整到所确定的积分时间值，以及获取由所述传感器提供的光强度测量值，从而能够形成光谱。

    Interrogating multi-featured arrays
    2.
    发明申请
    Interrogating multi-featured arrays 有权
    询问多功能阵列

    公开(公告)号：US20020058283A1

    公开(公告)日：2002-05-16

    申请号：US10036999

    申请日：2001-12-21

    Inventor： Andreas N. Dorsel ,  Kyle J. Schleifer ,  Elecia C. White ,  Charles S. Ladd ,  Debra A. Sillman

    IPC: C12Q001/68 ,  G01N033/53 ,  G06F019/00 ,  G01N033/48 ,  G01N033/50 ,  G06K009/00

    CPC classification number: G01N21/6452 ,  G01N21/274 ,  G01N21/6428 ,  G01N2201/1242

    Abstract: A method, apparatus for executing the method, and computer program products for use in such an apparatus. The method includes scanning an interrogating light across multiple sites on an array package including an addressable array of multiple features of different moieties, which scanned sites include multiple array features. Signals from respective scanned sites emitted in response to the interrogating light are detected. The interrogating light power is altered for a first site on the array package during the array scan, based on location of the first site or on a determination that the emitted signal from the first site will be outside a predetermined value absent the altering (which allows for protecting a detector against expected overly bright sites), or is altered during the array scan based on the detected interrogating light power (which allows for compensating for light source drift during an array scan).

    Abstract translation: 一种用于执行该方法的方法，装置以及用于这种装置的计算机程序产品。 该方法包括在阵列封装上的多个位置扫描询问光，其包括不同部分的多个特征的可寻址阵列，该扫描的位置包括多个阵列特征。 检测来自响应询问光发射的相应扫描位置的信号。 在阵列扫描期间，基于第一个场所的位置或确定来自第一个场地的发射信号将超出预定值，而不改变（允许 用于保护检测器免受预期的过亮点），或者在阵列扫描期间基于检测到的询问光功率（其允许补偿阵列扫描期间的光源漂移）而被改变。

    Methods and systems for nucleic acid sequencing validation, calibration and normalization
    4.
    发明授权
    Methods and systems for nucleic acid sequencing validation, calibration and normalization 有权
    用于核酸测序验证，校准和归一化的方法和系统

    公开(公告)号：US09169515B2

    公开(公告)日：2015-10-27

    申请号：US13030818

    申请日：2011-02-18

    Applicant: Min-Yi Shen ,  Douglas Greiner

    Inventor： Min-Yi Shen ,  Douglas Greiner

    IPC: C12Q1/68 ,  B01J8/00 ,  C07H21/00 ,  C12Q1/48 ,  C07H21/04

    CPC classification number: C12Q1/6874 ,  B01J2219/005 ,  C12Q2533/107 ,  C12Q2535/122 ,  G01N2201/1242 ,  G06F19/22 ,  C12Q2563/149 ,  C12Q2545/101

    Abstract: A system for performing quality control for nucleic acid sample sequencing is disclosed. The system comprises a set of solid supports, each solid support having attached thereto a plurality of nucleic acid sequences, wherein the set comprises plural groups of solid supports and each group contains solid supports having the same nucleic acid sequences attached thereto. The nucleic acid sequences of each group differ from each other. The nucleic acid sequences are synthetically derived, and the nucleic acids sequences are designed such that the nucleic acid sequences produce a predefined pattern of detectable signals during a sequencing run. A method of preparing a quality control for performing nucleic acid sample sequencing, a method of validating a nucleic acid sequencing instrument during a nucleic acid sequencing experiment, and a method of processing nucleic acid sequencing data during a nucleic acid sequencing experiment are also disclosed.

    Abstract translation: 公开了一种用于进行核酸样品测序的质量控制的系统。 该系统包含一组固体支持物，每个固体支持物附着有多个核酸序列，其中该组包含多组固体支持物，并且每组含有与其相连的相同核酸序列的固体支持物。 各组的核酸序列彼此不同。 核酸序列是合成衍生的，并且设计核酸序列使得核酸序列在测序运行期间产生可检测信号的预定模式。 还公开了制备用于进行核酸样品测序的质量控制的方法，在核酸测序实验期间验证核酸测序仪的方法，以及在核酸测序实验期间处理核酸测序数据的方法。

    ONBOARD DEVICE AND METHOD FOR ANALYZING FLUID IN A HEAT ENGINE
    5.
    发明申请
    ONBOARD DEVICE AND METHOD FOR ANALYZING FLUID IN A HEAT ENGINE 有权
    用于分析热发动机中的流体的ONBOARD装置和方法

    公开(公告)号：US20150300951A1

    公开(公告)日：2015-10-22

    申请号：US14648874

    申请日：2013-12-04

    Applicant: SP3H

    Inventor： Sylvain OBERTI ,  Johan FOURNEL

    IPC: G01N21/3577 ,  G01N21/27

    CPC classification number: G01N21/3577 ,  G01N21/274 ,  G01N21/3504 ,  G01N2021/3181 ,  G01N2201/062 ,  G01N2201/0624 ,  G01N2201/121 ,  G01N2201/1211 ,  G01N2201/124 ,  G01N2201/1242 ,  G01N2201/1247 ,  G01N2201/127 ,  G01N2201/12723

    Abstract: The present invention relates to a method for controlling a spectrometer for analyzing a product, the spectrometer including a light source including several light-emitting diodes having respective emission spectra covering in combination an analysis wavelength band, the method including steps of: supplying at least one of the light-emitting diodes with a supply current to switch it on, measuring a light intensity emitted by the light source by measuring a current at a terminal of at least another of the light-emitting diodes maintained off, determining, according to each light intensity measurement, a setpoint value of the supply current of each diode that is on, and regulating the supply current of each diode that is on so that it corresponds to the setpoint value.

    Abstract translation: 本发明涉及一种用于分析产品的光谱仪的控制方法，该光谱仪包括具有多个发光二极管的光源，该发光二极管具有组合分析波长带的各发射光谱，该方法包括以下步骤：将至少一个 的发光二极管与供电电流接通，通过测量至少另一个发光二极管的端子上的电流来测量由光源发射的光强度，根据每个光 强度测量，导通的每个二极管的电源电流的设定值，以及调节导通的每个二极管的电源电流，使其对应于设定值。

    METHODS AND SYSTEMS FOR NUCLEIC ACID SEQUENCING VALIDATION, CALIBRATION AND NORMALIZATION
    7.
    发明申请
    METHODS AND SYSTEMS FOR NUCLEIC ACID SEQUENCING VALIDATION, CALIBRATION AND NORMALIZATION 审中-公开
    用于核酸序列确认，校准和正常化的方法和系统

    公开(公告)号：US20160076095A1

    公开(公告)日：2016-03-17

    申请号：US14856614

    申请日：2015-09-17

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Min-Yi SHEN ,  Douglas GREINER

    IPC: C12Q1/68

    CPC classification number: C12Q1/6869 ,  B01J2219/005 ,  C12Q1/6874 ,  C12Q2533/107 ,  C12Q2535/122 ,  C12Q2545/101 ,  G01N2201/1242 ,  G16B30/00 ,  C12Q2563/149

    Abstract: A system for performing quality control for nucleic acid sample sequencing is disclosed. The system comprises a set of solid supports, each solid support having attached thereto a plurality of nucleic acid sequences, wherein the set comprises plural groups of solid supports and each group contains solid supports having the same nucleic acid sequences attached thereto. The nucleic acid sequences of each group differ from each other. The nucleic acid sequences are synthetically derived, and the nucleic acids sequences are designed such that the nucleic acid sequences produce a predefined pattern of detectable signals during a sequencing run. A method of preparing a quality control for performing nucleic acid sample sequencing, a method of validating a nucleic acid sequencing instrument during a nucleic acid sequencing experiment, and a method of processing nucleic acid sequencing data during a nucleic acid sequencing experiment are also disclosed.

    Abstract translation: 公开了一种用于进行核酸样品测序的质量控制的系统。 该系统包含一组固体支持物，每个固体支持物附着有多个核酸序列，其中该组包含多组固体支持物，并且每组含有与其相连的相同核酸序列的固体支持物。 各组的核酸序列彼此不同。 核酸序列是合成衍生的，并且设计核酸序列使得核酸序列在测序运行期间产生可检测信号的预定模式。 还公开了制备用于进行核酸样品测序的质量控制的方法，在核酸测序实验期间验证核酸测序仪的方法，以及在核酸测序实验期间处理核酸测序数据的方法。

    AUTOMATIC ANALYZER
    8.
    发明申请
    AUTOMATIC ANALYZER 有权
    自动分析仪

    公开(公告)号：US20150010435A1

    公开(公告)日：2015-01-08

    申请号：US14322275

    申请日：2014-07-02

    Applicant: KABUSHIKI KAISHA TOSHIBA ,  Toshiba Medical Systems Corporation

    Inventor： Satoshi MATSUMOTO ,  Tetsuya Higashi ,  Masakazu Kitamura

    IPC: G01N35/00 ,  G01N35/02

    CPC classification number: G01N35/0098 ,  G01N21/253 ,  G01N35/00693 ,  G01N35/025 ,  G01N2035/00702 ,  G01N2201/1242

    Abstract: According to one embodiment, an automatic analyzer includes a magnetic field generator, a photometric unit, a measurement unit, and a decision unit. The magnetic field generator causes magnetic separation in a reaction liquid stored in a cuvette by magnetic particles. The photometric unit includes a light source unit configured to generate light, and a detection unit configured to detect the light generated by the light source unit and generate an output signal corresponding to the detected light. The measurement unit measures a measurement item based on the output signal. The decision unit decides the use range of the output signal to be used to measure the measurement item in accordance with spatial unevenness of the magnetic separation by the magnetic field generator.

    Abstract translation: 根据一个实施例，自动分析仪包括磁场发生器，测光单元，测量单元和决定单元。 磁场发生器通过磁性颗粒在储存在比色皿中的反应液中进行磁分离。 测光单元包括被配置为产生光的光源单元，以及检测单元，被配置为检测由光源单元生成的光并产生与检测到的光相对应的输出信号。 测量单元根据输出信号测量测量项目。 决定单元根据磁场发生器的磁分离的空间不均匀性来决定要用于测量测量项目的输出信号的使用范围。

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