公开(公告)号：US20110039755A1

公开(公告)日：2011-02-17

申请号：US12989154

申请日：2009-04-23

Applicant: Philip KRAFT

Inventor： Philip KRAFT

IPC: C07C49/115 ,  C07C49/11 ,  A61K8/35 ,  A61Q13/00

CPC classification number: C11B9/003 ,  C07C49/21 ,  C07C403/16 ,  C07C2601/10 ,  C07C2601/16 ,  C11B9/0034 ,  C11B9/0038 ,  C11B9/0057

Abstract: A method of providing to a fragrance application a musky odour, comprising the addition thereto of at least one compound according to the formula I in which R1 is selected from H and CH3; R2, R3 are selected from the possibilities that (a) both are CH3; and (b) R2 and R3 together form a single bond (as indicated by the broken line); and n is an integer selected from 1, 2, 3, and 4. The compounds are useful in the complete range of fine and functional fragrance applications.

Abstract translation: 向香料应用提供麝香气味的方法，包括向其中加入至少一种其中R 1选自H和CH 3的式I化合物; R2，R3选自（a）都是CH3的可能性; 和（b）R2和R3一起形成单键（如虚线所示）; 并且n是选自1,2,3和4的整数。该化合物可用于完整范围的精细和功能性香料应用中。

公开(公告)号：US07807712B2

公开(公告)日：2010-10-05

申请号：US11018923

申请日：2004-12-22

Applicant: Ram Pratap ,  Mavurapu Satyanarayana ,  Chandeshwar Nath ,  Ram Raghubir ,  Anju Puri ,  Ramesh Chander ,  Priti Tiwari ,  Brajendra Kumar Tripathi ,  Arvind Kumar Srivastava

Inventor： Ram Pratap ,  Mavurapu Satyanarayana ,  Chandeshwar Nath ,  Ram Raghubir ,  Anju Puri ,  Ramesh Chander ,  Priti Tiwari ,  Brajendra Kumar Tripathi ,  Arvind Kumar Srivastava

IPC: A61K31/36 ,  A61K31/427 ,  A61K31/085 ,  C07D317/06 ,  C07C49/105 ,  C07C49/11 ,  A61P3/10 ,  A61P9/10

CPC classification number: C07D295/092 ,  C07D277/34 ,  C07D317/54 ,  C07D417/12

Abstract: The present invention provides appropriately substituted chalcones, such as, for example, represented by the structural formula as shown herein below Wherein R1, R2 and R3 are selected from the group consisting of H, OH, O-alkyl, O-phenyl and O-substituted phenyl; B represents Ar—Z—O or RO; where Z is an alkane having up to 5 carbon atoms; R is substituted propanol amino, wherein substituted amino groups are selected from the group consisting of t-butyl, n-butyl, i-butyl, i-propyl, 4-phenyl piperazine-1-yl, 4-(2-methoxyphenyl)-piperazin-1-yl and 3,4-dimethoxy phenethyl; and Ar is thiazolidine-dione methylene phenoxy. The compounds prepared have been demonstrated to exhibit significant antidiabetic effect in various animal models indicating potential for further exploitation.

Abstract translation: 本发明提供适当取代的查尔酮，例如由如下文所示的结构式表示，其中R1，R2和R3选自H，OH，O-烷基，O-苯基和O- 取代的苯基; B表示Ar-Z-O或RO; 其中Z是具有至多5个碳原子的烷烃; R是取代的丙醇氨基，其中取代的氨基选自叔丁基，正丁基，异丁基，异丙基，4-苯基哌嗪-1-基，4-（2-甲氧基苯基） - 哌嗪-1-基和3,4-二甲氧基苯乙基; Ar是噻唑烷二酮亚甲基苯氧基。 已经证明所制备的化合物在各种动物模型中表现出显着的抗糖尿病作用，表明有可能进一步开发。

公开(公告)号：US07432303B2

公开(公告)日：2008-10-07

申请号：US11074545

申请日：2005-03-08

Applicant: J. Phillip Bowen ,  Thomas Philip Robinson ,  Tedman Ehlers ,  David Goldsmith ,  Jack Arbiser

Inventor： J. Phillip Bowen ,  Thomas Philip Robinson ,  Tedman Ehlers ,  David Goldsmith ,  Jack Arbiser

IPC: C07C49/11 ,  C07C49/115 ,  A61K31/12

CPC classification number: C07D207/333 ,  C07C49/217 ,  C07C49/223 ,  C07C49/233 ,  C07C49/235 ,  C07C49/683 ,  C07C49/697 ,  C07C49/782 ,  C07C49/796 ,  C07C49/813 ,  C07C49/84 ,  C07D213/50 ,  C07D307/46

Abstract: The present invention relates to chalcone and chalcone derivatives and analogs which are useful as angiogenesis inhibitors. The present compounds, which are inexpensive to synthesize, exhibit unexpectedly good activity as angiogenesis inhibitors. The present invention also relates to the use of chalcone and its analogs as antitumor/anticancer agents and to treat a number of conditions or disease states in which angiogenesis is a factor, including angiongenic skin diseases such as psoriasis, acne, rosacea, warts, eczema, hemangiomas, lymphangiogenesis, among numerous others, as well as chronic inflammatory disease such as arthritis.

Abstract translation: 本发明涉及可用作血管发生抑制剂的查耳酮和查耳酮衍生物和类似物。 合成成本低的本发明化合物作为血管生成抑制剂表现出意想不到的良好活性。 本发明还涉及查耳酮及其类似物作为抗肿瘤/抗癌剂并用于治疗血管生成是其中一个因素的许多病症或疾病状态，包括银屑病，痤疮，酒渣鼻，疣，湿疹 ，血管瘤，淋巴管生成等等，以及慢性炎性疾病如关节炎。

公开(公告)号：US4868339A

公开(公告)日：1989-09-19

申请号：US100115

申请日：1987-09-23

Applicant: Philip A. Christenson ,  Brian J. Drake

Inventor： Philip A. Christenson ,  Brian J. Drake

IPC: A61K8/34 ,  A61K8/35 ,  A61Q13/00 ,  C07C33/14 ,  C07C43/162 ,  C07C47/11 ,  C07C47/225 ,  C07C49/11 ,  C07C49/21 ,  C07C403/08 ,  C07C403/12 ,  C07C403/16 ,  C11B9/00

CPC classification number: C11B9/0034 ,  C07C33/14 ,  C07C403/08 ,  C07C403/14 ,  C07C403/16 ,  C07C43/162 ,  C07C47/225 ,  C07C49/11 ,  C07C49/21 ,  C07B2200/09 ,  C07C2101/16

Abstract: Multimethyl cyclohexene or cyclohexane derivatives having woody, spicy, amber or violet odors are disclosed. The derivatives can be formulated into perfurmes, talcs, lotions, cremes and air fresheners.

Abstract translation: 公开了具有木质，辛香，琥珀色或紫色气味的多甲基环己烯或环己烷衍生物。 衍生物可以配制成perfurmes，talcs，洗剂，cremes和空气清新剂。

公开(公告)号：US4719032A

公开(公告)日：1988-01-12

申请号：US842692

申请日：1986-03-21

Applicant: Andreas Wachtler ,  Joachim Krause ,  Reinhard Hittich ,  Bernhard Scheuble

Inventor： Andreas Wachtler ,  Joachim Krause ,  Reinhard Hittich ,  Bernhard Scheuble

IPC: C07C49/11 ,  C07C41/00 ,  C07C43/184 ,  C07C45/00 ,  C07C67/00 ,  C07C69/013 ,  C09K19/30 ,  C09K19/42 ,  C09K19/44 ,  C09K19/46 ,  C09K19/54 ,  G02F1/13 ,  C09K19/34

CPC classification number: C09K19/3028 ,  C07C43/184 ,  C09K19/3066 ,  C09K19/42

Abstract: Cyclohexane derivatives of formula IR.sup.1 --Cy--CH.sub.2 --Q--(Cy).sub.m --O--(CO).sub.n --CH.sub.2 --R.sup.2 IwhereR.sup.1 denotes alkyl with 1 to 12 C atoms in which also one or two non-adjacent CH.sub.2 groups may be replaced by --O--, --CO--, --O--CO--, --CO--O-- or --CH.dbd.CH--,R.sup.2 denotes H, alkyl with 1 to 12 C atoms in which also one or two non-adjacent CH.sub.2 groups may be replaced by --O--, --CO--, --O--CO-- or --CO--O--,Cy denotes trans-1,4-cyclohexyleneQ denotes --CH.sub.2 -- or --O--,m denotes 1 or 2, andn denotes 0 or 1,are suitable as components of liquid-crystalline phases.

Abstract translation: 式I的环己烷衍生物R1-Cy-CH2-Q-（Cy）mO-（CO）n-CH2-R2 I其中R1表示具有1至12个C原子的烷基，其中一个或两个不相邻的CH2基团可以是 被-O - ， - CO-，-O-CO-，-CO-O-或-CH = CH-取代，R 2表示H，具有1至12个C原子的烷基，其中还有一个或两个不相邻的CH 2基团 可以被-O-，-CO-，-O-CO-或-CO-O-代替，Cy表示反式-1,4-亚环己基，Q表示-CH2-或-O-，m表示1或2， n表示0或1，适合作为液晶相的组分。

公开(公告)号：US4070374A

公开(公告)日：1978-01-24

申请号：US587183

申请日：1975-06-16

Applicant: Alan J. Chalk ,  Steven A. Magennis

Inventor： Alan J. Chalk ,  Steven A. Magennis

IPC: C07C43/23 ,  B01J21/00 ,  B01J23/00 ,  B01J31/00 ,  C07B61/00 ,  C07C27/00 ,  C07C29/44 ,  C07C33/28 ,  C07C33/34 ,  C07C37/14 ,  C07C39/11 ,  C07C39/19 ,  C07C41/00 ,  C07C45/00 ,  C07C45/51 ,  C07C47/228 ,  C07C49/11 ,  C07C49/20 ,  C07C49/213 ,  C07C49/82 ,  C07C51/00 ,  C07C59/48 ,  C07C59/74 ,  C07C65/01 ,  C07C65/30 ,  C07C65/32 ,  C07C67/00 ,  C07C69/035 ,  C07C69/76 ,  C07C201/00 ,  C07C205/19 ,  C07C205/45 ,  C07C233/65 ,  C07C253/00 ,  C07C255/54 ,  C07C255/56 ,  C07D307/28 ,  C07D317/54 ,  C07D317/06

CPC classification number: C07C47/228 ,  C07C45/512 ,  C07C49/11 ,  C07C49/213 ,  C07D307/28 ,  C07D317/54

Abstract: Upon reacting an alcohol having an olefinic double bond with an aryl bromide or iodide in the presence of a Paladium catalyst, there is provided either an aryl substituted aldehyde, ketone or olefinic alcohol.

Abstract translation: 在Paladium催化剂存在下，使具有烯属双键的醇与芳基溴或碘化物反应时，可以提供芳基取代的醛，酮或烯醇。

公开(公告)号：US2600766A

公开(公告)日：1952-06-17

申请号：US7103449

申请日：1949-01-14

Applicant: SHELL DEV

Inventor： HEARNE GEORGE W ,  SCHWARZER CARL G

IPC: C07C45/52 ,  C07C45/54 ,  C07C45/64 ,  C07C47/19 ,  C07C47/192 ,  C07C47/27 ,  C07C49/11 ,  C07C49/12 ,  C07C49/213 ,  C07C49/303 ,  C07C49/76

CPC classification number: C07C49/12 ,  C07C45/52 ,  C07C45/54 ,  C07C45/64 ,  C07C47/19 ,  C07C47/192 ,  C07C47/27 ,  C07C49/11 ,  C07C49/213 ,  C07C49/303 ,  C07C49/76

公开(公告)号：US10894757B2

公开(公告)日：2021-01-19

申请号：US15916370

申请日：2018-03-09

Applicant: King Abdulaziz University

Inventor： Mohamed Abdel Salam ,  Hind Al-Johani

IPC: B01J37/34 ,  C07C29/48 ,  B01J21/06 ,  B01J23/58 ,  B01J23/92 ,  B01J35/00 ,  B01J35/02 ,  B01J35/10 ,  B01J37/02 ,  B01J37/04 ,  B01J37/08 ,  B01J37/16 ,  C07C45/27 ,  C07C35/08 ,  C07C49/11

Abstract: Methods of preparing Pt/SrTiO3 photocatalysts comprising strontium titanate nanoparticles and platinum doped on a surface of the strontium titanate nanoparticles are described. Processes of oxidizing cycloalkanes to cycloalkanols and/or cycloalkanones by employing the Pt/SrTiO3 photocatalysts are specified. A method for recycling the photocatalyst is also provided.

公开(公告)号：US08119041B2

公开(公告)日：2012-02-21

申请号：US10233424

申请日：2002-09-04

Applicant: Masaharu Akiba ,  Jun Kawamata

Inventor： Masaharu Akiba ,  Jun Kawamata

IPC: G02F1/361 ,  G03F7/04 ,  G03F7/031 ,  C09K11/06 ,  C07C49/11 ,  G03C1/12 ,  G11B7/244 ,  G11B7/245 ,  G11B7/247

CPC classification number: B82Y10/00 ,  A61K41/008 ,  G03F7/0045 ,  G03F7/029 ,  G03F7/031 ,  G11B7/0045 ,  G11B7/005 ,  G11B7/244 ,  G11B7/245 ,  G11B7/246 ,  G11B7/247 ,  G11B7/249 ,  G11B7/26

Abstract: The present invention provides a two-photon light-emitting compound represented by formula (1), an optical data recording medium comprising a compound represented by formula (1), a two-photon polymerizable composition comprising a polymerizable monomer or polymerizable oligomer and at least compound represented by formula (1), and a photopolymerization process: X2—(—CR4═CR3—)m—C(═O)—(—CR1═CR2—)n—X1  (1) wherein X1 and X2 may be the same or different and each represent a substituted or unsubstituted aryl group or a substituted or unsubstituted heterocyclic group; R1, R2, R3 and R4 each independently represent a hydrogen atom or substituent; some of R1, R2, R3 and R4 may be connected to each other to form at least one ring; and n and m each independently represent an integer of from 1 to 4, with the proviso that when n and m are 2 or more, the plurality of R1's, R2's, R3's, and R4's each may be the same or different.

Abstract translation: 本发明提供一种由式（1）表示的双光子发光化合物，包含由式（1）表示的化合物的光学数据记录介质，包含可聚合单体或可聚合低聚物的双光子可聚合组合物和至少 式（1）表示的化合物和光聚合方法：X2 - （ - CR4 = CR3-）m-C（= O） - （ - CR1 = CR2-）n-X1（1）其中X1和X2可以是 各自表示取代或未取代的芳基或取代或未取代的杂环基; R1，R2，R3和R4各自独立地表示氢原子或取代基; R 1，R 2，R 3和R 4中的一些可以彼此连接以形成至少一个环; n和m各自独立地表示1〜4的整数，条件是当n和m为2以上时，多个R 1，R 2，R 3和R 4各自可以相同或不同。

公开(公告)号：US20100080862A1

公开(公告)日：2010-04-01

申请号：US12557365

申请日：2009-09-10

Applicant: Hiroaki YAJIMA ,  Yutaka Miura ,  Daisuke Fujiwara ,  Hideharu Odai ,  Keiji Kondo ,  Hajime Nozawa

Inventor： Hiroaki YAJIMA ,  Yutaka Miura ,  Daisuke Fujiwara ,  Hideharu Odai ,  Keiji Kondo ,  Hajime Nozawa

IPC: A61K31/12 ,  C07C49/11 ,  C07C49/115 ,  C07C49/15 ,  A61P3/04 ,  A61P3/10 ,  A61K36/00

CPC classification number: A61K31/122 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/185 ,  A23V2250/21

Abstract: It is intended to provide compositions and foods for use in the treatment, prophylaxis, or amelioration of diseases or symptoms which can be treated, prevented or ameliorated by activating PPAR, in particular, insulin resistant diabetes and hyperlipidemia. Namely, medicinal compositions usable in treating, preventing or improving diseases or symptoms which can be treated, prevented or ameliorated by activation PPAR which contain humulones, isohumulones or lupulones or pharmaceutically acceptable salts or solvates thereof.

Abstract translation: 旨在提供用于治疗，预防或改善可通过激活PPAR，特别是胰岛素抵抗型糖尿病和高脂血症治疗，预防或改善的疾病或症状的组合物和食品。 也就是说，可用于治疗，预防或改善可通过激活含有葎草酮，异葎草酮或杜松酮的PPAR或其药学上可接受的盐或溶剂化物的治疗，预防或改善的疾病或症状的药物组合物。