摘要:
Compounds of formula (1) as well as their salts and esters are disclosed wherein X, X', Z and Y are as described in the specification and which have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4. Such compounds are useful for treating diseases whose symptoms and/or damage are related to the binding of VCAM-1 to cells expressing VLA-4.
摘要:
Small molecule compounds having aggregation-induced emission (AIE) characteristics. The compounds include organic, aromatic salts having anion-π + interactions. In some embodiments, the anion-π + interactions can include heavy-atom-anion- π + interactions. The heavy atom anions can include bromine or iodide, for example. The compounds can be water-soluble. The compounds can be useful as probes for bioimaging, as room temperature luminogens for electroluminescent devices, and white organic light-emitting applications.
摘要:
A process of preparing a zinc chalcogenide includes providing a solution of 8-hydroxyquinoline; a zinc precursor; and a reaction solvent; isolating a precipitate from the solution; and calcining the precipitate to form the zinc chalcogenide. Additionally, a polymer composite may include a polymer, bis(8-hydroxyquinolinato)zinc, and elemental sulfur or bis(8-hydroxyquinolinato) z M, wherein M is a metal ion and the value of z is equivalent to the oxidation state of the metal ion.
摘要:
The present invention relates to quinobenzoxazines analogs having the general formula: (I)and pharmaceutically acceptable salts, esters and prodrugs thereof; wherein A, U, W, X, Z, B, L, R 1 , R 3 , R 4 and R 5 are substituents.The present invention also relates to methods for using such compounds.
摘要:
Disclosed is a metal-containing coordination compound represented by the formula (1) below and having characteristics equivalent to or better than those of metal complexes which can be polymerized or dissolved in a solvent. Also disclosed is a coordination compound residue-containing polymer compound which is a polymer compound having characteristics equivalent to or better than those of metal complexes. Further disclosed is an organic electroluminescent material having characteristics equivalent to or better than those of metal complexes such as Alq3 which can be easily formed into a film by a method for processing an organic polymer compound, or can be dissolved in a solvent and easily formed into a film by a casting method. Still further disclosed are a light-emitting device and a white light-emitting device which can be produced by using such an organic electroluminescent material without requiring a deposition process.
摘要:
Process for the preparation of the facial isomer of tris(8-oxoquinoline)aluminum(III) (Alq 3 ), comprising the step of heating α-Alq 3 in solid phase at a temperature equal to or higher than 350°C but lower than 420°C, to obtain a mixture of γ -Alq 3 and δ-Alq 3 .
摘要:
The present technology provides compounds, as well as compositions including such compounds, useful in targeted radiotherapy (e.g., uranium therapy) of cancer and/or mammalian tissue overexpressing e.g., an antigen or a receptor, where the compounds are represented by the following Formulas or a pharmaceutically acceptable salt and/or solvate thereof, or a pharmaceutically acceptable salt and/or solvate thereof, or a pharmaceutically acceptable salt and/or solvate thereof, wherein M1 is independently at each occurrence a radionuclide. Equivalents of such compounds are also disclosed.
摘要:
The present disclosure relates to abnormal N-Heterocyclic Carbene complexes. The present disclosure also relates to synthesis, characterization and applications of abnormal N-Heterocyclic Carbene Complex.