公开(公告)号：WO2005059506A2

公开(公告)日：2005-06-30

申请号：PCT/US2004/021688

申请日：2004-07-06

Applicant: JOHNS HOPKINS UNIVERSITY ,  REICH, Daniel, H. ,  TANASE, Monica ,  CHEN, Christopher, S.

Inventor： REICH, Daniel, H. ,  TANASE, Monica ,  CHEN, Christopher, S.

IPC: G01N

CPC classification number: B01L3/502761 ,  B01L2200/0668 ,  B01L2300/0877 ,  B01L2300/0896 ,  B01L2400/043 ,  B01L2400/0487 ,  B03C1/01 ,  B03C1/288 ,  B03C2201/18 ,  B03C2201/26 ,  B82Y30/00 ,  C12M47/04 ,  C12N13/00

Abstract: In accordance with the invention, a surface is provided with a plurality of microscale magnets ("micromagnets") disposed on a surface in a pattern to form a desired distribution of magnetic field strength. Cells and magnetic nanowires are attached, immersed in fluid, and flowed over the pattern. The nanowires and their bound cells are attracted to and bound to regions of the pattern as controlled by the geometry and magnetic properties of the pattern, the strength and direction of the fluid flow, and the strength and direction of an applied magnetic field.

Abstract translation: 根据本发明，表面设有多个以图案形式设置在表面上的微细磁体（“微型磁体”），以形成所需的磁场强度分布。 将细胞和磁性纳米线连接，浸入流体中，并流过图案。 由图案的几何形状和磁特性，流体流动的强度和方向以及施加的磁场的强度和方向来控制纳米线及其结合的细胞被吸引并结合到图案的区域。

公开(公告)号：WO2005032512A2

公开(公告)日：2005-04-14

申请号：PCT/US2004/032491

申请日：2004-09-30

Applicant: TRUSTEES OF STEVENS INSTITUTE OF TECHNOLOGY ,  SUKHISHVILI, Svetlana, A. ,  KOZLOVSKAYA, Veronika ,  KHARLAMPIEVA, Eugenia

Inventor： SUKHISHVILI, Svetlana, A. ,  KOZLOVSKAYA, Veronika ,  KHARLAMPIEVA, Eugenia

IPC: A61K9/00

CPC classification number: A61K9/5089

Abstract: Micro-, and nano-scale capsules comprising neutral (uncharged) polymeric layers, layers associated by hydrogen bonding and methods for making such capsules. The capsules of the invention are layered upon a core particle using a layer-by layer-technique. The capsule walls of the capsules of the invention give a tailored response to external stimuli.

Abstract translation: 包含中性（不带电）的聚合物层，通过氢键结合的层的微米级和纳米级胶囊以及用于制备这种胶囊的方法。 使用逐层技术将本发明的胶囊层压在核心颗粒上。 本发明的胶囊的胶囊壁给予外部刺激的定制响应。

公开(公告)号：WO2005016502A1

公开(公告)日：2005-02-24

申请号：PCT/US2004/001386

申请日：2004-01-20

Applicant: ADVANCED BIOMATERIAL SYSTEMS, INC.

IPC: B01F13/00

CPC classification number: B01F13/002 ,  A61B17/8833 ,  A61B2017/8838 ,  A61B2050/0064 ,  A61F2002/30561 ,  A61F2002/4685 ,  A61F2250/0071 ,  B01F7/00408 ,  B01F13/0033 ,  B01F13/06 ,  B01F15/00435 ,  B01F15/00506 ,  B01F15/0205 ,  B01F15/0206 ,  B01F15/0212 ,  B01F15/0216 ,  B01F15/0225 ,  B01F15/0237 ,  B01F15/0258 ,  B01F15/0267 ,  B01F15/027 ,  B01F15/0278 ,  B01F15/0279 ,  B01F2215/0029

Abstract: Apparatus and methods for mixing and dispensing components. The methods and apparatus of the invention are particularly advantageous to manually mix the components of radiopaque bone cement and inject the resulting radiopaque bone cement into skeletal structures. The manually actuated apparatus of the invention comprises: (1) a sealed mixing chamber (295) for mixing components; (2) a dispensing chamber (305) isolated from the sealed mixing chamber; (3) a controllable portal (300) to open a flow path between the sealed mixing chamber and the dispensing chamber so that the dispensing chamber can receive the mixed components after they are mixed; and (4) a drive mechanism (410) associated with the dispensing chamber to force the mixed contents from the dispensing chamber.

Abstract translation: 用于混合和分配组件的装置和方法。 本发明的方法和装置特别有利于手动混合不透射线骨水泥的组分并将所得的不透射线骨水泥注射到骨骼结构中。 本发明的手动致动装置包括：（1）用于混合部件的密封混合室（295）; （2）与密封的混合室隔离的分配室（305）; （3）可控制的入口（300），用于打开所述密封的混合室和所述分配室之间的流动路径，使得所述分配室可以在混合后容纳所述混合组分; 和（4）与分配室相关联的驱动机构（410），以迫使来自分配室的混合内容物。

公开(公告)号：WO2005007215A2

公开(公告)日：2005-01-27

申请号：PCT/US2004/021352

申请日：2004-07-02

Applicant: GLUCOLIGHT CORPORATION

Inventor： SHURMAN, MATTHEW, J.

IPC: A61M

CPC classification number: A61B5/0066 ,  A61B5/14551

Abstract: In accordance with the invention, the oxygenation of blood-profused tissue is measured by shining light into the profused tissue and analyzing the light reflected within the tissue. The light is reflected by cell walls in the tissue and is partially absorbed by hemoglobin in the blood. Since the extent of absorption is sensitive to the extent of hemoglobin oxygenation, measurement and processing of the reflected light provides a measure of the oxygenation of the blood. In one embodiment, the method is applied to measure the oxygenation of blood within the tympanic membrane (ear drum).

Abstract translation: 根据本发明，通过将光照射到多余的组织中并分析在组织内反射的光来测量血液灌注组织的氧合。 光被组织中的细胞壁反射，并被血液中的血红蛋白部分吸收。 由于吸收程度对血红蛋白氧合程度敏感，所以反射光的测量和处理提供了血液氧合作用的量度。 在一个实施方案中，该方法用于测量鼓膜内的血液的氧合作用。

公开(公告)号：WO2004046778A3

公开(公告)日：2004-06-03

申请号：PCT/US2003/036923

申请日：2003-11-19

Applicant: VYTRAN CORPORATION

Inventor： MIES, Eric ,  VENKATARAMAN, Latha

IPC: G02B6/255

Abstract: The invention is directed to methods for adiabatically expanding the mode-field diameter of an optical fiber (20) by heating the end (30) of the optical fiber. The fiber’s end is heated by a heat source, preferably, a flame (50) fueled by an organic liquid. Preferably, the organic-liquid fuel is an alcohol, more preferably, an alcohol having six or fewer carbon atoms and only one hydroxyl group, and optimally methanol.

公开(公告)号：WO2004032275A3

公开(公告)日：2004-04-15

申请号：PCT/US2003/026570

申请日：2003-08-23

Applicant: THE REGENTS FO THE UNIVERSITY OF CALIFORNIA ,  JIN, Sungho

Inventor： JIN, Sungho

IPC: H01J1/02

Abstract: In accordance with the invention, improved vacuum microtube devices are provided with arrangements for tunably spacing the gate and the cathode. Tuning can be effected by using an electrostatic or magnetic actuator to move the gate on a spring or a rail. Advantageously a feedback arrangement can be used to control the spacing. Magnetic reassembly components can be provided for facilitating release of tube components in fabrication.

公开(公告)号：WO2004017691A1

公开(公告)日：2004-02-26

申请号：PCT/US2002/037350

申请日：2002-11-15

Applicant: DI/DT, INC. ,  ROY, Apurba

Inventor： ROY, Apurba

IPC: H05K5/00

CPC classification number: H01R12/57 ,  H01L23/49811 ,  H01L2924/0002 ,  H01L2924/3011 ,  H01R12/52 ,  H05K3/3426 ,  H05K3/368 ,  H05K2201/1031 ,  H05K2201/10666 ,  H05K2201/10856 ,  Y02P70/611 ,  H01L2924/00

Abstract: An I-channel surface mount connector (10) includes a generally I-shaped cross section with extended mounting flange (13A, 14B).

Abstract translation: I沟道表面安装连接器（10）包括具有延伸的安装凸缘（13A，14B）的大致I形横截面。

公开(公告)号：WO2004013743A2

公开(公告)日：2004-02-12

申请号：PCT/US2003/024842

申请日：2003-07-29

Applicant: FARMS TECHNOLOGY

Inventor： TATGE, Jason, G. ,  FRITSCH, Daniel, S.

IPC: G06F

CPC classification number: G06Q40/04 ,  G06Q30/0226 ,  G06Q30/0601 ,  G06Q30/0635 ,  G06Q30/0641 ,  G06Q30/08

Abstract: The invention is directed to methods and systems for commodities procurement with concomitant hedging. The invention enables automatic commodity purchase at a desired basis level when a seller’s price matches a buyer’s basis bid and concomitantly automatically placing an electronic commodities order to hedge the buyer’s purchase.

Abstract translation: 本发明涉及用于商品采购的方法和系统，伴随着套期保值。 当卖方的价格与买方基准投标相匹配并且伴随地自动地放置电子商品订单以对冲买方的购买时，本发明使得能够以期望的基础水平自动商品购买。

公开(公告)号：WO2007127931A2

公开(公告)日：2007-11-08

申请号：PCT/US2007/067653

申请日：2007-04-27

Applicant: REACTIVE NANOTECHNOLOGIES, INC. ,  VAN HEERDEN, David, P. ,  RUDE, Timothy, Ryan ,  NEWSON, Jesse, E. ,  HE, Zhaojuan ,  BESNOIN, Etienne ,  VINCENT, Ramzi ,  WEIHS, Timothy, P.

Inventor： VAN HEERDEN, David, P. ,  RUDE, Timothy, Ryan ,  NEWSON, Jesse, E. ,  HE, Zhaojuan ,  BESNOIN, Etienne ,  VINCENT, Ramzi ,  WEIHS, Timothy, P.

IPC: H01L23/48

CPC classification number: H01L24/29 ,  B23K1/0006 ,  H01L24/16 ,  H01L24/32 ,  H01L24/83 ,  H01L2224/16 ,  H01L2224/27013 ,  H01L2224/29101 ,  H01L2224/29111 ,  H01L2224/73253 ,  H01L2224/83051 ,  H01L2224/838 ,  H01L2924/00013 ,  H01L2924/01013 ,  H01L2924/01029 ,  H01L2924/01049 ,  H01L2924/0105 ,  H01L2924/01075 ,  H01L2924/01079 ,  H01L2924/01082 ,  H01L2924/0132 ,  H01L2924/01322 ,  H01L2924/014 ,  H01L2924/10253 ,  H01L2924/14 ,  H01L2924/15747 ,  H01L2924/1579 ,  H01L2924/19041 ,  H01L2924/3025 ,  H01L2924/00 ,  H01L2924/00014 ,  H01L2224/29099

Abstract: The present inventors have observed that in some applications of reactive composite joining there is escape of a portion of the molten joining material through the edges of the joining regions. Such escape is not only a waste of expensive material (e.g. gold or indium) but also a reduction from the optimal thickness of the joining regions. In some applications, such escape also presents risk of short circuits or even fire. In this invention, two approaches are taken toward preventing damage to surroundings by the escape of molten joining material. First, escape may be prevented by trapping or containing the molten material near the joint, using barriers, dams, or similar means. Second, escape may be reduced by adjusting parameters within the joint, such as solder composition, joining pressure, or RCM thickness.

Abstract translation: 本发明人已经观察到，在反应性复合物接合的一些应用中，熔融接合材料的一部分通过接合区域的边缘逸出。 这种逃逸不仅浪费昂贵的材料（例如金或铟），而且还减少了接合区域的最佳厚度。 在某些应用中，这种逃生也存在短路或甚至火灾的风险。 在本发明中，采取两种途径来防止熔融接合材料的逸出对周围环境的损害。 首先，可以通过使用屏障，水坝或类似手段在接头附近捕获或容纳熔融材料来防止逃逸。 其次，通过调节接头内的参数，例如焊料组成，接合压力或RCM厚度，可以减少泄漏。

公开(公告)号：WO2005079199A2

公开(公告)日：2005-09-01

申请号：PCT/US2004/033782

申请日：2004-10-13

Applicant: NOBLE DEVICE TECHNOLOGIES ,  KING, Clifford, Alan ,  RAFFERTY, Conor

Inventor： KING, Clifford, Alan ,  RAFFERTY, Conor

IPC: H01L27/146 ,  H01L27/148 ,  H01L31/028

CPC classification number: H01L27/14634 ,  H01L27/146 ,  H01L27/1463 ,  H01L27/148 ,  H01L31/028 ,  H01L2924/351 ,  Y02E10/547

Abstract: In accordance with the invention, an improved image sensor comprises an array of germanium photosensitive elements integrated with a silicon substrate and integrated with silicon readout circuits. The silicon transistors are formed first on a silicon substrate, using well known silicon wafer fabrication techniques. The germanium elements are subsequently formed overlying the silicon by epitaxial growth. The germanium elements are advatageously grown within surface openings of a dielectric cladding. Wafer fabrication techniques are applied to the elements to form isolated germanium photodiodes. Since temperatures needed for germanium processing are lower than those for silicon processing, the formation of the germanium devices need not affect the previously formed silicon devices. Insulating and metallic layers are then deposited and patterned to interconnect the silicon devices and to connect the germanium devices to the silicon circuits. The germanium elements are thus integrated to the silicon by epitaxial growth and integrated to the silicon circuitry by common metal layers.

Abstract translation: 根据本发明，改进的图像传感器包括与硅衬底集成并与硅读出电路集成的锗感光元件的阵列。 首先使用公知的硅晶片制造技术在硅衬底上形成硅晶体管。 随后通过外延生长将锗元素覆盖在硅上。 锗元素在电介质包层的表面开口内被广泛地生长。 将晶片制造技术应用于元件以形成分离的锗光电二极管。 由于锗处理所需的温度低于硅处理所需的温度，锗器件的形成不必影响先前形成的硅器件。 然后沉积和图案化绝缘和金属层以互连硅器件并将锗器件连接到硅电路。 因此，锗元素通过外延生长与硅集成到一起，并通过公共金属层与硅电路集成。