BIOMARKER OF RENAL IMPAIRMENT
    1.
    发明申请
    BIOMARKER OF RENAL IMPAIRMENT 审中-公开
    生物标志物的外伤

    公开(公告)号:WO2013004647A1

    公开(公告)日:2013-01-10

    申请号:PCT/EP2012/062798

    申请日:2012-07-02

    CPC classification number: G01N33/6893 G01N33/493 G01N2800/347

    Abstract: There is provided a method of determining whether a subject belongs to a first or a second group of subjects, wherein the risk of having or developing of a renal impairment is higher in the first group than in the second group, comprising the steps of: a) measuring an amount of fibulin 1 in a sample from the subject to obtain a sample value; b) comparing the sample value to a reference value; and if the sample value is higher than the reference value, c1) concluding that the subject belongs to the first group; and if the sample value is lower than the reference value, c2) concluding that the subject belongs to the second group, wherein the sample is an optionally modified sample derived from urine or blood, such as an optionally diluted serum or plasma sample. Associated means are also provided.

    Abstract translation: 提供了确定受试者是否属于第一组或第二组受试者的方法,其中在第一组中具有或发展肾损伤的风险高于第二组,其包括以下步骤:a )测量来自受试者的样品中的纤维蛋白1的量以获得样品值; b)将样本值与参考值进行比较; 并且如果样本值高于参考值,则c1)认定该受试者属于第一组; 并且如果样品值低于参考值,则c2)断定受试者属于第二组,其中样品是衍生自尿液或血液的任选修饰的样品,例如任选稀释的血清或血浆样品。 还提供了相关的手段。

    COOLING CIRCUIT FOR A VEHICLE AND VEHICLE COMPRISING A COOLING CIRCUIT
    2.
    发明申请
    COOLING CIRCUIT FOR A VEHICLE AND VEHICLE COMPRISING A COOLING CIRCUIT 审中-公开
    用于包含冷却电路的车辆和车辆的冷却电路

    公开(公告)号:WO2010147517A8

    公开(公告)日:2012-02-16

    申请号:PCT/SE2009000310

    申请日:2009-06-18

    CPC classification number: F01P7/16 F01P2060/06 F02M26/30 F02M26/32

    Abstract: The invention relates to a cooling circuit (90) for a vehicle (100), particularly a commercial vehicle, wherein the cooling circuit (90) comprises a combustion engine (10), a retarder cooler (30) for cooling a retarder (32), an EGR cooler (40) for cooling an exhaust gas of the combustion engine (10), and a coolant cooler (20) which is coupled to the combustion engine (10) for cooling the combustion engine (10) by means of a coolant. The retarder cooler (30) is arranged permanently in series with the EGR cooler (40) in a fluid path (60) of the coolant forming a return line for the coolant from the combustion engine (10) to the coolant cooler (20).

    Abstract translation: 本发明涉及一种用于车辆(100)的冷却回路(90),特别是商业车辆,其中冷却回路(90)包括内燃机(10),用于冷却减速器(32)的减速器冷却器(30) ,用于冷却所述内燃机(10)的排气的EGR冷却器(40)和冷却剂冷却器(20),所述冷却剂冷却器(20)联接到所述内燃机(10),以通过冷却剂冷却所述内燃机(10) 。 延迟冷却器(30)在冷却剂的流体路径(60)中永久地与EGR冷却器(40)串联布置,所述冷却剂形成用于冷却剂从内燃机(10)到冷却剂冷却器(20)的返回管线。

    A CHUCK, AND A METHOD FOR BRINGING A FIRST AND A SECOND SUBSTRATE TOGETHER
    3.
    发明申请
    A CHUCK, AND A METHOD FOR BRINGING A FIRST AND A SECOND SUBSTRATE TOGETHER 审中-公开
    一种螯合剂,以及一种制备第一和第二种基材的方法

    公开(公告)号:WO2012007520A1

    公开(公告)日:2012-01-19

    申请号:PCT/EP2011/061990

    申请日:2011-07-13

    Abstract: A chuck (100, 200, 500) for holding a master electrode (107, 207) or a substrate (111, 211) during an ECPR process is provided. The chuck comprises an interaction surface (102, 201) onto which the master electrode (107, 207) or the substrate (111, 211) is arranged, and attaching means (105, 205) for clamping said master electrode (107, 207) or said substrate (111, 211) to said interaction surface (102, 201) such that said master electrode (107, 207) or said substrate (111, 211) is conforming to the shape of said interaction surface (102, 201). Further, a method for bringing a master electrode in contact with a substrate in an ECPR process is provided. The method comprises the steps of arranging a master electrode or a substrate on a chuck, arranging a substrate or a master electrode on a second chuck, aligning said master electrode and said substrate such that a front side of said master electrode is at a distance from and facing a front side of said substrate, and bringing the front side of the master electrode into contact with the front side of the substrate by decreasing said distance such that a centre of the master electrode contacts a centre of the substrate, and continuously decreasing said distance while also continuously decreasing said convex shape.

    Abstract translation: 提供了一种用于在ECPR处理期间保持主电极(107,207)或基板(111,211)的卡盘(100,200,500)。 所述卡盘包括配置有所述主电极(107,207)或所述基板(111,211)的相互作用面(102,201),以及用于夹持所述主电极(107,207)的连接单元(105,205) 或所述衬底(111,211)到所述相互作用表面(102,201),使得所述主电极(107,207)或所述衬底(111,211)符合所述相互作用表面(102,201)的形状。 此外,提供了在ECPR处理中使主电极与基板接触的方法。 该方法包括以下步骤:将主电极或基板布置在卡盘上,将基板或主电极布置在第二卡盘上,使所述主电极和所述基板对准,使得所述主电极的前侧距离 并且面向所述基板的前侧,并且通过减小所述距离使主电极的前侧与基板的前侧接触,使得主电极的中心接触基板的中心,并且连续地减小所述 距离同时也连续地减小所述凸形。

    SLIDING DOOR ARRANGEMENT
    4.
    发明申请
    SLIDING DOOR ARRANGEMENT 审中-公开
    滑动门装置

    公开(公告)号:WO2011121070A1

    公开(公告)日:2011-10-06

    申请号:PCT/EP2011/055005

    申请日:2011-03-31

    Abstract: The present disclosure relates to a sliding door arrangement including a sliding door, a rail system, with a rail which guides a sliding motion of the door, and an attenuation and retraction device, which brakes the sliding motion of the door at a brake position in the vicinity of a door end position and retracts the door to the end position. The door has a wheel, which is arranged to run on the rail, a pin, slideably mounted on the door, which is arranged to interact with the attenuation and retraction device, and optionally a pin movement limiting device, which, at least in a mounting position, limits the movement of the pin such that it does not extend further from the door than does said wheel.

    Abstract translation: 本发明涉及一种滑动门装置,其包括滑动门,轨道系统,轨道系统,其引导门的滑动运动;以及衰减和收回装置,其将门的滑动运动制动在制动位置 门端位置附近,并将门缩回到终端位置。 门具有轮,其布置成在轨道上运行,可滑动地安装在门上的销,其布置成与衰减和收回装置相互作用,以及可选地,销移动限制装置,其至少在 安装位置,限制销的运动,使得它不比所述轮更远离门延伸。

    METHOD OF MANUFACTURING AN ELECTRICAL CIRCUIT ON A SUBSTRATE
    6.
    发明申请
    METHOD OF MANUFACTURING AN ELECTRICAL CIRCUIT ON A SUBSTRATE 审中-公开
    在基板上制造电路的方法

    公开(公告)号:WO2010136596A3

    公开(公告)日:2011-02-03

    申请号:PCT/EP2010057505

    申请日:2010-05-28

    Abstract: Electrical components, e.g., radiators, are made by a method comprising the steps of (1) providing a substrate, e.g., a polymeric film, having a first facial side that has a metal coating, e.g., copper, and a second facial side that does not have a metal coating; (2) applying an etchresist to the metal coating to define a trace; (3) etching from the substrate the metal coating not covered by the etch-resist; (4) removing the etch-resist from the metal coating; and (5) plating, e.g., electroless plating, the uncovered metal coating with a plating material comprising at least one of silver, gold, and nickel.

    Abstract translation: 电子部件例如散热器通过包括以下步骤的方法制成:(1)提供具有第一面部侧的基底,例如聚合物膜,所述第一面部侧具有金属涂层,例如铜,以及第二面部侧, 没有金属涂层; (2)对金属涂层施加蚀刻蚀刻以界定痕迹; (3)从衬底上蚀刻未被抗蚀剂覆盖的金属涂层; (4)从金属涂层去除蚀刻抗蚀剂; 以及(5)用包含银,金和镍中的至少一种的镀覆材料电镀例如化学镀,未覆盖的金属涂层。

    METHOD OF MANUFACTURING AN ELECTRICAL CIRCUIT ON A SUBSTRATE
    7.
    发明申请
    METHOD OF MANUFACTURING AN ELECTRICAL CIRCUIT ON A SUBSTRATE 审中-公开
    在基板上制造电路的方法

    公开(公告)号:WO2010136596A2

    公开(公告)日:2010-12-02

    申请号:PCT/EP2010/057505

    申请日:2010-05-28

    Abstract: Electrical components, e.g., radiators, are made by a method comprising the steps of (1) providing a substrate, e.g., a polymeric film, having a first facial side that has a metal coating, e.g., copper, and a second facial side that does not have a metal coating; (2) applying an etchresist to the metal coating to define a trace; (3) etching from the substrate the metal coating not covered by the etch-resist; (4) removing the etch-resist from the metal coating; and (5) plating, e.g., electroless plating, the uncovered metal coating with a plating material comprising at least one of silver, gold, and nickel.

    Abstract translation: 电子部件例如散热器通过包括以下步骤的方法制成:(1)提供具有第一面部侧的基底,例如聚合物膜,所述第一面部侧具有金属涂层,例如铜,以及第二面部侧, 没有金属涂层; (2)对金属涂层施加蚀刻蚀刻以限定痕迹; (3)从衬底上蚀刻未被抗蚀剂覆盖的金属涂层; (4)从金属涂层去除蚀刻抗蚀剂; 以及(5)用包含银,金和镍中的至少一种的镀覆材料电镀例如化学镀,未覆盖的金属涂层。

    INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION
    10.
    发明申请
    INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION 审中-公开
    不适用于治疗炎症

    公开(公告)号:WO2010076566A2

    公开(公告)日:2010-07-08

    申请号:PCT/GB2009/002977

    申请日:2009-12-30

    Inventor: NILSSON, Peter

    CPC classification number: C07D209/42 C07D401/12

    Abstract: There is provided compounds of formula I, wherein ring R 1a to R 1c , R 2a to R 2e , and X have meanings given in the description, and pharmaceutically-acceptable salts thereof, which compounds are useful in the treatment of diseases in which inhibition of leukotriene C 4 synthase is desired and/or required, and particularly in the treatment of a respiratory disorder and/or inflammation.

    Abstract translation: 提供式I化合物,其中R1a至R1c,R2a至R2e和X分别具有说明书中给出的含义及其药学上可接受的盐,该化合物可用于治疗白三烯C4合酶抑制疾病 是需要和/或需要的,特别是在治疗呼吸障碍和/或炎症中。

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