公开(公告)号：US20140198313A1

公开(公告)日：2014-07-17

申请号：US14008964

申请日：2012-03-27

Applicant: David Tracy ,  Peter Lewis Stokes ,  Sepehr Kiani

Inventor： David Tracy ,  Peter Lewis Stokes ,  Sepehr Kiani

IPC: G01J3/42 ,  G01J3/44

CPC classification number: G01J3/42 ,  G01J3/0208 ,  G01J3/021 ,  G01J3/0216 ,  G01J3/0248 ,  G01J3/0291 ,  G01J3/06 ,  G01J3/08 ,  G01J3/10 ,  G01J3/14 ,  G01J3/18 ,  G01J3/2803 ,  G01J3/44 ,  G01J3/4406 ,  G01N15/1434 ,  G01N15/1459 ,  G01N15/1484 ,  G01N21/6456

Abstract: The present invention generally pertains to a system, method and kit for the detection and measurement of spectroscopic properties of light from a sample, or the scalable detection and measurement of spectroscopic properties of light from each sample present among multiple samples, simultaneously, wherein the system comprises: an optical train comprising a dispersing element; and an image sensor. The light detected and measured may comprise light scattered from a sample, emitted as chemiluminescence by a chemical process within a sample, selectively absorbed by a sample, or emitted as fluorescence from a sample following excitation.

Abstract translation: 本发明一般涉及一种用于检测和测量来自样品的光的光谱特性的系统，方法和试剂盒，或同时进行多个样品中存在的每个样品的光的光谱特性的可伸缩检测和测量，其中系统 包括：包括分散元件的光学系列; 和图像传感器。 检测和测量的光可以包括从样品散射的光，通过样品内的化学过程作为化学发光发射，被样品选择性吸收，或者在激发后作为荧光从样品中发射。

公开(公告)号：US20110057117A1

公开(公告)日：2011-03-10

申请号：US12841725

申请日：2010-07-22

Applicant: Adrian Fawcett ,  David Tracy ,  Kevin Daley Simmons

Inventor： Adrian Fawcett ,  David Tracy ,  Kevin Daley Simmons

IPC: G01J1/58 ,  F21S4/00 ,  F21V5/00 ,  F21V9/16

CPC classification number: G01N21/6486 ,  B01L7/52 ,  B01L2300/046 ,  B01L2300/0829 ,  B01L2300/1805 ,  G01N21/0332 ,  G01N21/6452 ,  G01N2021/0367 ,  G01N2021/6421 ,  G01N2021/6471 ,  G01N2021/6478 ,  G01N2201/02 ,  G01N2201/062 ,  G01N2201/0626 ,  G01N2201/0627 ,  G01N2201/0636

Abstract: Optical systems, and corresponding methods, for multiple reactions are provided. The optical systems are in a fixed position relative to a thermal assembly and include at least one array of excitation sources (e.g., light emitting diodes (LEDs)) configured to output excitation energy along an excitation optical path. In addition, a detector configured to receive emission energy along a detection optical path in the same plane as the excitation optical path is also provided.

Abstract translation: 提供了多种反应的光学系统和相应的方法。 光学系统相对于热组件处于固定位置，并且包括被配置为沿着激发光路输出激发能量的至少一组激励源（例如，发光二极管（LED））。 此外，还提供了被配置为沿着与激励光路相同的平面中的检测光路接收发射能量的检测器。

公开(公告)号：US06658414B2

公开(公告)日：2003-12-02

申请号：US09800371

申请日：2001-03-06

Applicant: Edward Lee Bryan ,  David Tracy Bennett ,  Raymond Leo Idaszak ,  Suresh Balu

Inventor： Edward Lee Bryan ,  David Tracy Bennett ,  Raymond Leo Idaszak ,  Suresh Balu

IPC: G06F1730

CPC classification number: G06Q10/10 ,  H04L12/1895 ,  H04L51/00 ,  H04L67/26 ,  H04L67/306 ,  Y10S707/99939

Abstract: A method and system for creating, using, and updating individual user voice portals in a multi-user environment is disclosed. Each user selects data sources, keywords and time intervals for searching the data sources, and grammar for accessing search results. Based on this information, an individual voice portal is created for the user. The requested information is extracted from the specified data sources and cached or stored in a database to increase extraction speed. The user accesses the individual voice portal using a unique identifier assigned to the user and the selected grammar. Because each user has a unique voice portal, the search space for software that interprets the grammar is decreased. As a result, the likelihood of misinterpretation and the time for extracting the requested information are decreased.

公开(公告)号：US20100279299A1

公开(公告)日：2010-11-04

申请号：US12753806

申请日：2010-04-02

Applicant: George Maltezos ,  Adrian Fawcett ,  Matthew Johnston ,  Xing Yang ,  David Tracy

Inventor： George Maltezos ,  Adrian Fawcett ,  Matthew Johnston ,  Xing Yang ,  David Tracy

IPC: C12Q1/68 ,  C12M1/02 ,  C12M1/34 ,  C12P19/34

CPC classification number: B01L7/52 ,  B01L2200/14 ,  B01L2300/0636 ,  B01L2300/0829 ,  B01L2300/1822 ,  B01L2300/185 ,  G01N2021/6439 ,  G01N2035/00356 ,  G01N2035/00366

Abstract: This invention provides a systems and methods for regulating temperature and heat transfer in applications in which it is desirable to maintain temperature uniformity such as thermal cycling applications. A heat block is used to rapidly transfer heat to or from a set of one or more reaction vessels.

Abstract translation: 本发明提供一种在需要保持诸如热循环应用的温度均匀性的应用中调节温度和热传递的系统和方法。 热块用于将热量快速传递到一组或多个反应容器的一个或多个反应容器。

公开(公告)号：US20060136568A1

公开(公告)日：2006-06-22

申请号：US11297218

申请日：2005-12-08

Applicant: Spencer Meister ,  David Tracy

Inventor： Spencer Meister ,  David Tracy

IPC: G06F15/16

CPC classification number: G07F11/72 ,  G06Q20/387 ,  G06Q30/0212 ,  G07F7/00 ,  G07F17/0014 ,  G07F17/42

Abstract: An apparatus for providing at least one item of value in cooperation with operation of a companion device delivering at least one first product to a user comprises: (a) a control means for controlling the providing; (b) a providing means for effecting the providing; the providing means being coupled with the control means; and (c) a link with the companion device for effecting the cooperation. The apparatus may further comprise (d) a communication means coupled with the control means for communicating operational information with the apparatus regarding operation of the apparatus; and (e) a memory means coupled with the communication means for storing the operational information.

Abstract translation: 一种用于与向用户递送至少一个第一产品的配套设备的操作协同提供至少一个价值项的设备包括：（a）控制提供的控制装置; （b）提供提供方式; 所述提供装置与所述控制装置耦合; 和（c）与配套设备的链接以实现合作。 所述设备还可以包括（d）与所述控制装置耦合的通信装置，用于与所述装置通信关于所述装置的操作的操作信息; 和（e）与所述通信装置耦合以存储操作信息的存储装置。

公开(公告)号：US20050162657A1

公开(公告)日：2005-07-28

申请号：US11074604

申请日：2005-03-07

Applicant: Dar Bahatt ,  Jerry Cahill ,  Koichi Nishikida ,  Enrico Picozza ,  Paul Saviano ,  David Tracy ,  Yongdong Wang

Inventor： Dar Bahatt ,  Jerry Cahill ,  Koichi Nishikida ,  Enrico Picozza ,  Paul Saviano ,  David Tracy ,  Yongdong Wang

IPC: G01N21/27 ,  G01N21/55

CPC classification number: G01N21/7703 ,  G01N21/553

Abstract: An optical resonance analysis system comprising a sensor means (60) and an illumination means (400) for generating non-monochromatic illumination. The illumination means (400) further comprises a means for generating illumination at a plurality of angles, a lens system for projecting said illumination at said plurality of angles (390) and a dispersive device (380) for dispersing said illumination at each of said plurality of angles so that there is a correlation between said plurality of angles and the wavelengths of said illumination such that a resonance condition is generated on said sensor mean (60) for all wavelengths generated by said non-monochromatic source simultaneously. The analysis system also comprises a detection means (90) for detecting the reflected or transmitted illumination. Another embodiment comprises an anamorphic imaging means (120).

Abstract translation: 一种光学共振分析系统，包括传感器装置（60）和用于产生非单色照明的照明装置（400）。 照明装置（400）还包括用于以多个角度产生照明的装置，用于以所述多个角度（390）投射所述照明的透镜系统和用于将所述照明分散在所述多个角度的分散装置（380） 的角度，使得在所述多个角度和所述照明的波长之间存在相关性，使得对于由所述非单色源同时产生的所有波长的所述传感器平均值（60）产生共振条件。 分析系统还包括用于检测反射或透射照明的检测装置（90）。 另一实施例包括变形成像装置（120）。

公开(公告)号：US5720923A

公开(公告)日：1998-02-24

申请号：US299033

申请日：1994-08-31

Applicant: Lawrence A. Haff ,  Enrico Picozza ,  Will Bloch ,  Robert Ragusa ,  Joseph DiCesare ,  David Tracy ,  Paul Saviano ,  Timothy M. Woudenberg

Inventor： Lawrence A. Haff ,  Enrico Picozza ,  Will Bloch ,  Robert Ragusa ,  Joseph DiCesare ,  David Tracy ,  Paul Saviano ,  Timothy M. Woudenberg

IPC: C12N15/09 ,  B01J19/00 ,  B01L7/00 ,  C12M1/00 ,  C12Q1/68 ,  C40B40/06 ,  C40B60/14 ,  G01N35/00 ,  C12M1/40 ,  C12P19/34

CPC classification number: B01L7/525 ,  B01J19/0046 ,  B01L7/52 ,  B01L9/065 ,  B01J2219/00495 ,  B01J2219/00722 ,  B01L2300/1883 ,  C12Q1/686 ,  C40B40/06 ,  C40B60/14 ,  G01N2035/00237 ,  Y10T436/116664

Abstract: Apparatus and method for performing a nucleic acid amplification reaction and preferably a polymerase chain reaction (PCR) in a reaction mixture in at least one capillary tube. Several different embodiments are disclosed. One embodiment cycles a sample through a capillary tube loop passing through two thermostatted fluid baths. Another embodiment has the capillary tube routed alternatingly between two heat exchangers to that the sample makes only one pass through the tube. Other embodiments maintain the heat exchangers stationary and translate the samples between them. Still further embodiments maintain the samples stationary and either automatically translate or rotate the heat exchangers past the samples contained within the capillary tubes to perform the thermal cycles necessary for the amplification reaction.

公开(公告)号：US09068947B2

公开(公告)日：2015-06-30

申请号：US13132315

申请日：2009-12-03

Applicant: Adrian Fawcett ,  David Tracy

Inventor： Adrian Fawcett ,  David Tracy

IPC: G01N21/03 ,  G02B5/04 ,  C12Q1/68 ,  G01N21/64 ,  B01L3/00

CPC classification number: G01N21/6452 ,  B01L3/50851 ,  C12Q1/686 ,  G01N21/0303 ,  G01N21/0332 ,  G01N2021/6417 ,  G01N2021/6463 ,  G02B5/04 ,  G02B5/045

Abstract: The invention relates to optical systems and methods for measurement of samples in multiple sample vessels using an array of light sources where the light from the light sources is divided into multiple light beams, and each beam is directed to a sample vessel.

Abstract translation: 本发明涉及用于使用光源阵列测量多个样品容器中的样品的光学系统和方法，其中来自光源的光被分成多个光束，并且每个光束被引导到样品容器。

公开(公告)号：US20070109542A1

公开(公告)日：2007-05-17

申请号：US10566303

申请日：2004-08-02

Applicant: David Tracy ,  Jennifer Brockman ,  Keith Ferrara ,  Martin Shenker ,  Robert Kersten ,  Steven Cohen ,  Gary Bodley ,  Patrick Tuxbury ,  Paul Hetherington ,  Enrico Picozza

Inventor： David Tracy ,  Jennifer Brockman ,  Keith Ferrara ,  Martin Shenker ,  Robert Kersten ,  Steven Cohen ,  Gary Bodley ,  Patrick Tuxbury ,  Paul Hetherington ,  Enrico Picozza

IPC: G01N21/55

CPC classification number: G01N21/553

Abstract: An optical analysis unit especially suitable for performing grating coupled surface plasmon resonance (SPR) imaging features a pivoting light source capable of scanning through a range of angles of incident light projected onto a stationary target sensor, such as an SPR sensor. The reflected image from the illuminated sensor is detected, e.g., by a CCD camera and the image and angular scan data are processed, for example by a fitting algorithm, to provide real time analysis of reactions taking place on the surface of the sensor.

Abstract translation: 特别适用于执行光栅耦合表面等离子体共振（SPR）成像的光学分析单元具有能够扫描投射到固定目标传感器（例如SPR传感器）上的入射光的角度范围的枢转光源。 例如通过CCD照相机检测来自照明传感器的反射图像，并且例如通过拟合算法处理图像和角度扫描数据，以提供在传感器的表面上发生的反应的实时分析。

公开(公告)号：US20150226672A1

公开(公告)日：2015-08-13

申请号：US14620998

申请日：2015-02-12

Applicant: Adrian Fawcett ,  David Tracy ,  Kevin Daley Simmons

Inventor： Adrian Fawcett ,  David Tracy ,  Kevin Daley Simmons

IPC: G01N21/64 ,  B01L7/00 ,  G01N21/03

CPC classification number: G01N21/6486 ,  B01L7/52 ,  B01L2300/046 ,  B01L2300/0829 ,  B01L2300/1805 ,  G01N21/0332 ,  G01N21/6452 ,  G01N2021/0367 ,  G01N2021/6421 ,  G01N2021/6471 ,  G01N2021/6478 ,  G01N2201/02 ,  G01N2201/062 ,  G01N2201/0626 ,  G01N2201/0627 ,  G01N2201/0636

Abstract: Optical systems, and corresponding methods, for multiple reactions are provided. The optical systems are in a fixed position relative to a thermal assembly and include at least one array of excitation sources (e.g., light emitting diodes (LEDs)) configured to output excitation energy along an excitation optical path. In addition, a detector configured to receive emission energy along a detection optical path in the same plane as the excitation optical path is also provided.

Abstract translation: 提供了多种反应的光学系统和相应的方法。 光学系统相对于热组件处于固定位置，并且包括被配置为沿着激发光路输出激发能量的至少一组激励源（例如，发光二极管（LED））。 此外，还提供了被配置为沿着与激励光路相同的平面中的检测光路接收发射能量的检测器。