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公开(公告)号:US10392578B2
公开(公告)日:2019-08-27
申请号:US13151014
申请日:2011-06-01
申请人: Stephen Robert Cherinko , Robert Cody Kertis , Kirk E. Apt , Paul Warren Behrens , Jon Milton Hansen , Joseph W. Pfeifer, III , Tracey Lynn Stahl , Ross Zirkle , Nasrin Tabayeh Burke , Krishna Raman , Neil Francis Leininger
发明人: Stephen Robert Cherinko , Robert Cody Kertis , Kirk E. Apt , Paul Warren Behrens , Jon Milton Hansen , Joseph W. Pfeifer, III , Tracey Lynn Stahl , Ross Zirkle , Nasrin Tabayeh Burke , Krishna Raman , Neil Francis Leininger
摘要: The present invention relates to processes for obtaining a lipid from a cell by lysing the cell, contacting the cell with a base and/or salt, and separating the lipid. The present invention is also directed to a lipid prepared by the processes of the present invention. The present invention is also directed to microbial lipids having a particular anisidine value, peroxide value, and/or phosphorus content.
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公开(公告)号:US09262238B2
公开(公告)日:2016-02-16
申请号:US13363150
申请日:2012-01-31
申请人: Tobias Kunze , Ram Ranganathan , Krishna Raman , Rajat Chopra
发明人: Tobias Kunze , Ram Ranganathan , Krishna Raman , Rajat Chopra
摘要: A computing device detects an event generated by a first component that publishes a connection endpoint, the event indicating that the connection endpoint of the first component has been modified. The computing device determines a second component that subscribes to the connection endpoint. The computing device updates a location of the connection endpoint in a data structure associated with the second component to maintain a connection between the first component and the second component.
摘要翻译: 计算设备检测由发布连接端点的第一组件生成的事件,该事件指示第一组件的连接端点已被修改。 计算设备确定预订连接端点的第二组件。 计算设备更新与第二组件相关联的数据结构中的连接端点的位置,以维持第一组件和第二组件之间的连接。
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公开(公告)号:US20080021103A1
公开(公告)日:2008-01-24
申请号:US11903458
申请日:2007-09-21
IPC分类号: A61K47/30 , A61K31/165 , A61K31/192 , A61K31/24
CPC分类号: A61K9/006 , A61K9/7015 , A61K47/32
摘要: The invention is directed to a topical medicament-containing composition which exhibits excellent bioadhesive properties suitable for application to the human body, including to mucous membranes.
摘要翻译: 本发明涉及一种局部含药组合物,其表现出优异的生物粘附性能,其适用于人体,包括粘膜。
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公开(公告)号:US5180830A
公开(公告)日:1993-01-19
申请号:US690760
申请日:1991-04-24
申请人: Gleason O. Cookson , Vu A. Dang , Krishna Raman
发明人: Gleason O. Cookson , Vu A. Dang , Krishna Raman
IPC分类号: B01J23/04 , B01J31/02 , C07B61/00 , C07C67/03 , C07D211/46 , C07D401/12 , C08K5/3435 , C09K15/30
CPC分类号: C07D211/46
摘要: Disclosed is a process for the preparation of hindered amine light stabilizers by reacting (a) an alkyl substituted-4-hydroxypiperidine with (b) a dicarboxylic acid ester, in the presence of a catalyst system comprising a basic inorganic compound and a polar aprotic organic compound.
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5.
公开(公告)号:US5009893A
公开(公告)日:1991-04-23
申请号:US381218
申请日:1989-07-17
IPC分类号: A23G3/00 , A23G3/34 , A23G3/36 , A23G3/50 , A23G3/54 , A23G4/00 , A23G4/02 , A23G4/06 , A23G4/20 , A23L27/20 , A61K8/00 , A61K8/11 , A61K8/42 , A61K8/73 , A61Q11/00
摘要: An edible composition capable of providing long-lasting, breath freshening perception without bitterness which comprises using in said edible composition a cooling composition comprising methanol and an N-substituted-p-methane carboxamide compound.
摘要翻译: 一种能够提供持久,呼吸清新感觉而不产生苦味的可食用组合物,其包括在所述食用组合物中使用包含甲醇和N-取代对甲烷甲酰胺化合物的冷却组合物。
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公开(公告)号:US20140323569A1
公开(公告)日:2014-10-30
申请号:US14234104
申请日:2012-07-20
申请人: Krishna Raman
发明人: Krishna Raman
IPC分类号: A61K31/232 , A61K31/202
CPC分类号: A61K31/232 , A21D2/165 , A23D9/00 , A23K20/158 , A23L5/00 , A23L7/104 , A23L9/00 , A23L31/00 , A23L33/115 , A23V2002/00 , A61K31/202 , C11B1/00 , C11B1/10 , C11B3/04 , C11B3/06 , C11C3/003 , C11C3/10 , C12P7/6472 , C12R1/89 , A23V2200/326 , A23V2250/187 , A23V2250/1882
摘要: The present invention is directed to microbial oils that are enriched in their content of polyunsaturated fatty acids, their esters, their acid salts, alcohols formed therefrom, and/or aldehydes formed therefrom. The present invention is further directed to compositions containing the enriched microbial oils and methods of making and using the enriched microbial oils. The present invention is also directed to isolated microorganisms as well as strains and mutants thereof, biomasses, microbial oils, compositions, and cultures; methods of producing the microbial oils, biomasses, and mutants; and methods of using the isolated microorganisms, biomasses, and microbial oils.
摘要翻译: 本发明涉及富含多不饱和脂肪酸含量的微生物油,它们的酯,它们的酸盐,由其形成的醇和/或由其形成的醛。 本发明还涉及含有富集的微生物油的组合物和制备和使用富集的微生物油的方法。 本发明还涉及分离的微生物以及其菌株和突变体,生物质,微生物油,组合物和培养物; 生产微生物油,生物质和突变体的方法; 以及使用分离的微生物,生物质和微生物油的方法。
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7.
公开(公告)号:US20100130608A1
公开(公告)日:2010-05-27
申请号:US12572263
申请日:2009-10-01
申请人: Alan Stuart RYAN , Edward B. Nelson , Jung Lee , Krishna Raman
发明人: Alan Stuart RYAN , Edward B. Nelson , Jung Lee , Krishna Raman
IPC分类号: A61K31/22 , A61K31/202 , A61P3/00
CPC分类号: A61K31/232 , A61K31/20 , A61K31/201 , A61K2300/00
摘要: The present invention is directed to methods of reducing plasma triglyceride level in subjects by administering docosahexaenoic acid (DHA). The method can comprise administering daily to the subject a dosage form comprising docosahexaenoic acid ester substantially free of eicosapentaenoic acid (EPA), wherein the DHA is derived from an algal source. In some embodiments, the method comprises administering daily to the subject a dosage form comprising DHA ester substantially free of EPA, wherein the DHA ester is about 60% to about 99.5% (w/w) of the total fatty acid content of the dosage form. In some embodiments, the method comprises administering daily to the subject a dosage form comprising about 200 mg to about 4 g of DHA ester substantially free of EPA. In some embodiments, the foregoing methods also result in a lowering of the amount of total cholesterol in the subject.
摘要翻译: 本发明涉及通过施用二十二碳六烯酸(DHA)来减少受试者血浆甘油三酯水平的方法。 该方法可以包括向受试者施用基本上不含二十碳五烯酸(EPA)的二十二碳六烯酸酯的剂型,其中DHA来源于藻源。 在一些实施方案中,该方法包括向受试者施用包含基本上不含EPA的DHA酯的剂型,其中DHA酯为剂型总脂肪酸含量的约60%至约99.5%(w / w) 。 在一些实施方案中,该方法包括向受试者施用包含约200mg至约4g基本上不含EPA的DHA酯的剂型。 在一些实施方案中,前述方法还导致受试者中总胆固醇的量的降低。
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8.
公开(公告)号:US20090023808A1
公开(公告)日:2009-01-22
申请号:US12163555
申请日:2008-06-27
申请人: Krishna Raman , Jung Lee , Neil Leininger , Chris Luigart
发明人: Krishna Raman , Jung Lee , Neil Leininger , Chris Luigart
CPC分类号: C07C69/587 , A21D2/16 , A23K20/158 , A23L33/12 , C07C67/03 , C07C67/08 , C07C67/60 , C11C3/003 , C07C69/533
摘要: The present invention includes methods for producing and purifying esters of polyunsaturated fatty acids that include reacting a composition having triglycerides with polyunsaturated fatty acid residues in the presence of an alcohol and a base to produce an ester of a polyunsaturated fatty acid from the triglycerides. The composition can be a polyunsaturated fatty acid-containing composition that has not been conventionally processed. The reacted composition can be further processed by distillation.
摘要翻译: 本发明包括用于生产和纯化多不饱和脂肪酸酯的方法,其包括在醇和碱的存在下使具有甘油三酯的组合物与多不饱和脂肪酸残基反应以从甘油三酸酯生产多不饱和脂肪酸的酯。 组合物可以是未经常规加工的含多不饱和脂肪酸的组合物。 可以通过蒸馏进一步处理反应的组合物。
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公开(公告)号:US4983404A
公开(公告)日:1991-01-08
申请号:US361529
申请日:1989-06-05
IPC分类号: A23G4/00 , A23G4/20 , A23L27/00 , A61K8/00 , A61K8/18 , A61Q13/00 , B01F17/34 , C07H13/06 , C08L93/04 , C11B9/00
CPC分类号: A23G4/20 , A23L27/70 , A23V2002/00
摘要: A flavor delivery system is disclosed which offers the combination of improved flavor intensity and extension and, when incorporated into chewing gums, provides desired softness to the gum to facilitate the reduction in softening additives that conventionally add moisture thereto. The present delivery system comprises a composite of a flavor and a resin preferably in a solution mixture with each other, the flavor being present in an amount of from about 20% to about 80% of the final delivery system, with the resin comprising the remainder. Optionally, an emulsifier may be added in an amount of up to 25% by weight. In a further embodiment, the delivery system of the present invention may include up to 25% by weight of a sweetener such as acesulfame-K. The present delivery system finds use in comestibles such as chewing gum compositions and other food products, pharmaceuticals, and scratch-and-sniff and aroma packaging products. The delivery system may be incorporated as a liquid or may be prepared in particulate form.
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公开(公告)号:US20110295028A1
公开(公告)日:2011-12-01
申请号:US13151014
申请日:2011-06-01
申请人: Stephen Robert Cherinko , Robert Cody Kertis , Kirk E. Apt , Paul Warren Behrens , Jon Milton Hansen , Joseph W. Pfeifer, III , Tracey Lynn Stahl , Ross Zirkle , Nasrin Tabayeh Burke , Krishna Raman , Neil Francis Leininger
发明人: Stephen Robert Cherinko , Robert Cody Kertis , Kirk E. Apt , Paul Warren Behrens , Jon Milton Hansen , Joseph W. Pfeifer, III , Tracey Lynn Stahl , Ross Zirkle , Nasrin Tabayeh Burke , Krishna Raman , Neil Francis Leininger
摘要: The present invention relates to processes for obtaining a lipid from a cell by lysing the cell, contacting the cell with a base and/or salt, and separating the lipid. The present invention is also directed to a lipid prepared by the processes of the present invention. The present invention is also directed to microbial lipids having a particular anisidine value, peroxide value, and/or phosphorus content.
摘要翻译: 本发明涉及通过裂解细胞,使细胞与碱和/或盐接触并分离脂质从细胞获得脂质的方法。 本发明还涉及通过本发明的方法制备的脂质。 本发明还涉及具有特定茴香胺值,过氧化值和/或磷含量的微生物脂质。
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