公开(公告)号：US20090203544A1

公开(公告)日：2009-08-13

申请号：US12306289

申请日：2007-07-03

申请人： Anke Pierik ,  Johan Frederik Dijksman ,  Hendrik Roelof Stapert ,  Roy Gerardus Franciscus Antonius Verbeek ,  Aleksey Kolesnychenko

发明人： Anke Pierik ,  Johan Frederik Dijksman ,  Hendrik Roelof Stapert ,  Roy Gerardus Franciscus Antonius Verbeek ,  Aleksey Kolesnychenko

IPC分类号： C40B60/14 ,  C40B50/14 ,  C40B40/00

CPC分类号： G01N35/1074 ,  B01J19/0046 ,  B01J2219/0036 ,  B01J2219/00378 ,  B01J2219/00527 ,  B01J2219/00659 ,  B01J2219/00693 ,  G01N35/1016 ,  G01N2035/1076

摘要： The invention relates to a printer device for producing biological test arrays by depositing an array of biofluids onto a substrate. The invention further relates to the use of such a device in the production of biological test arrays. The invention also relates to a method for producing a biological test array. The invention moreover relates to a biological test array. The method according to the invention is failure-proof, and results in biological test arrays of superior quality.

摘要翻译： 本发明涉及一种用于通过将生物流体阵列沉积到基底上来生产生物测试阵列的打印机装置。 本发明还涉及这种装置在生物测试阵列生产中的应用。 本发明还涉及一种用于生产生物测试阵列的方法。 本发明还涉及生物测试阵列。 根据本发明的方法是无故障的，并且导致具有优良品质的生物测试阵列。

公开(公告)号：US20090264308A1

公开(公告)日：2009-10-22

申请号：US12301645

申请日：2007-05-22

申请人： Dirk Jan Broer ,  Roel Penterman ,  Ralph Kurt ,  Emiel Peeters ,  Hendrik Roelof Stapert ,  Anke Pierik ,  Aleksey Kolesnychenko ,  Hendrik De Koning

发明人： Dirk Jan Broer ,  Roel Penterman ,  Ralph Kurt ,  Emiel Peeters ,  Hendrik Roelof Stapert ,  Anke Pierik ,  Aleksey Kolesnychenko ,  Hendrik De Koning

IPC分类号： C40B30/04 ,  C12Q1/68 ,  C12M1/34 ,  C40B40/06

CPC分类号： G01K11/16 ,  B01L3/508 ,  B01L2200/147 ,  B01L2300/0636 ,  B01L2300/0663

摘要： This invention provides a biosensor solid or hydrogel substrate comprising one or more temperature indicating agents, each of said one or more temperature indicating agents operating by changing its optical properties and being deposited in and/or at the surface of the biosensor solid or hydrogel substrate as one or more layers and/or spots

摘要翻译： 本发明提供了包含一种或多种温度指示剂的生物传感器固体或水凝胶基质，所述一种或多种温度指示剂中的每一种通过改变其光学性质并沉积在生物传感器固体或水凝胶基质的表面和/ 一个或多个层和/或点

公开(公告)号：US20080303870A1

公开(公告)日：2008-12-11

申请号：US12158513

申请日：2006-12-19

申请人： Roy Gerardus Franciscus Antonius Verbeek ,  Richard Joseph Marinus Schroeders ,  Aleksey Kolesnychenko

发明人： Roy Gerardus Franciscus Antonius Verbeek ,  Richard Joseph Marinus Schroeders ,  Aleksey Kolesnychenko

IPC分类号： B41J2/05

CPC分类号： B41J3/28 ,  B01J19/0046 ,  B01J2219/0036 ,  B01J2219/00378 ,  B01J2219/00495 ,  B01J2219/00527 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00641 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00662 ,  B01J2219/00677 ,  B01J2219/00689 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01L3/0268 ,  B01L2300/0819 ,  B01L2300/1872 ,  B41J3/407

摘要： The invention provides an ink jet device for the positioning of a substance onto a substrate, the device comprising at least a print head comprising a nozzle provided to eject a droplet comprising the substance, the ink jet device further comprising at least one heating element arranged such that the substrate can be heated prior to, during and/or after the landing of a droplet on the substrate.

摘要翻译： 本发明提供了一种用于将物质定位到基底上的喷墨装置，该装置至少包括一个打印头，该打印头包括一个喷嘴，该喷嘴被设置成喷射包括该物质的液滴，喷墨装置还包括至少一个这样的加热元件 衬底可以在液滴在衬底上着落之前，期间和/或之后被加热。

公开(公告)号：US20090116125A1

公开(公告)日：2009-05-07

申请号：US12302049

申请日：2007-05-25

申请人： Aleksey Kolesnychenko ,  Sjoerd Stallinga ,  Hendrik Roelof Stapert

发明人： Aleksey Kolesnychenko ,  Sjoerd Stallinga ,  Hendrik Roelof Stapert

IPC分类号： G02B9/00 ,  G02B17/00 ,  G01J5/08

CPC分类号： G01J5/08 ,  G01J5/0037 ,  G01J5/0806 ,  G01J5/0809 ,  G01J5/0846 ,  G01J5/0862 ,  G01J5/089 ,  G01J5/602 ,  G01J2005/0077 ,  G01N2021/6478 ,  G02B27/42 ,  G02B27/4233

摘要： The present invention concerns a lens system. More specifically, it concerns a lens system comprising a first lens (3), a deflection element (5) and a second lens (6), wherein the deflection element (5) is arranged between the first lens (3) and the second lens (6). The deflection element comprises at least a first annular zone and a second annular zone, the annular zones being arranged in a concentric fashion and wherein the deflection angle of each annular zone is different from the deflection angle of every other annular zone. Furthermore, the present invention concerns a temperature analysis system comprising a lens system and the use of a temperature analysis system.

摘要翻译： 本发明涉及一种透镜系统。 更具体地，涉及一种包括第一透镜（3），偏转元件（5）和第二透镜（6）的透镜系统，其中偏转元件（5）布置在第一透镜（3）和第二透镜 （6）。 偏转元件至少包括第一环形区域和第二环形区域，环形区域以同心方式布置，并且其中每个环形区域的偏转角度与每隔一个环形区域的偏转角度不同。 此外，本发明涉及包括透镜系统和使用温度分析系统的温度分析系统。

公开(公告)号：US20110086361A1

公开(公告)日：2011-04-14

申请号：US12999641

申请日：2009-06-16

申请人： Derk Jan Wilfred Klunder ,  Anke Pierik ,  Aleksey Kolesnychenko ,  Marius Iosif Boamfa ,  Richard Joseph Marinus Schroeders

发明人： Derk Jan Wilfred Klunder ,  Anke Pierik ,  Aleksey Kolesnychenko ,  Marius Iosif Boamfa ,  Richard Joseph Marinus Schroeders

IPC分类号： C12Q1/68 ,  C12M1/34

CPC分类号： C12Q1/6834 ,  B01L7/525 ,  B01L7/54 ,  B01L2300/088 ,  B01L2300/0883 ,  C12Q1/686 ,  C12Q2565/519 ,  C12Q2561/113 ,  C12Q2527/101

摘要： The present invention relates to the amplification and detection of amplified nucleic acid sequences employing methods and devices with distinct temperature zones. The methods and devices of the present invention may be used for quantitative analysis of target nucleic acid sequences, for simultaneous quantitative analysis of multiple target nucleic acid sequences or for analyzing a sample for the presence of a target nucleic acid.

摘要翻译： 本发明涉及使用具有不同温度区的方法和装置扩增和检测扩增的核酸序列。 本发明的方法和装置可用于靶核酸序列的定量分析，用于同时定量分析多个靶核酸序列或用于分析样品中靶核酸的存在。

公开(公告)号：US08797503B2

公开(公告)日：2014-08-05

申请号：US13149404

申请日：2011-05-31

申请人： Joeri Lof ,  Antonius Theodorus Anna Maria Derksen ,  Christiaan Alexander Hoogendam ,  Aleksey Kolesnychenko ,  Erik Roelof Loopstra ,  Theodorus Marinus Modderman ,  Johannes Catharinus Hubertus Mulkens ,  Roelof Aeilko Siebrand Ritsema ,  Klaus Simon ,  Joannes Theodoor De Smit ,  Alexander Straaijer ,  Bob Streefkerk ,  Helmar Van Santen

发明人： Joeri Lof ,  Antonius Theodorus Anna Maria Derksen ,  Christiaan Alexander Hoogendam ,  Aleksey Kolesnychenko ,  Erik Roelof Loopstra ,  Theodorus Marinus Modderman ,  Johannes Catharinus Hubertus Mulkens ,  Roelof Aeilko Siebrand Ritsema ,  Klaus Simon ,  Joannes Theodoor De Smit ,  Alexander Straaijer ,  Bob Streefkerk ,  Helmar Van Santen

IPC分类号： G03B27/52

CPC分类号： G03F7/70341 ,  G03F7/707 ,  G03F7/7085 ,  G03F9/7088

摘要： In a lithographic apparatus, a liquid supply system to provide a liquid to a space between the table and an optical element and to contact a surface of the optical element, the space having a cross-sectional area smaller than the area of the substrate, the liquid supply system comprising a liquid confinement structure extending along at least a part of a boundary of the space between the optical element surface and the table, wherein at least part of the liquid confinement structure is positioned between the optical element surface and the table, the at least part of the liquid confinement structure has an aperture through which the patterned beam can pass, the liquid confinement structure comprises an inlet to supply the liquid to the space above the aperture, and the liquid confinement structure comprises an outlet to remove the liquid, supplied by the inlet, from the space below the aperture.

摘要翻译： 在光刻设备中，液体供应系统将液体提供到工作台与光学元件之间的空间并与光学元件的表面相接触，该空间的横截面积小于衬底的面积， 液体供应系统包括沿着光学元件表面和工作台之间的空间的边界的至少一部分延伸的液体限制结构，其中液体限制结构的至少一部分位于光学元件表面和工作台之间， 所述液体限制结构的至少一部分具有所述图案化束可以穿过的孔，所述液体限制结构包括将所述液体供应到所述孔上方的空间的入口，并且所述液体限制结构包括用于除去所述液体的出口， 由入口提供，从孔下方的空间。

公开(公告)号：US08208120B2

公开(公告)日：2012-06-26

申请号：US12078997

申请日：2008-04-09

申请人： Joeri Lof ,  Antonius Theodorus Anna Maria Derksen ,  Christiaan Alexander Hoogendam ,  Aleksey Kolesnychenko ,  Erik Roelof Loopstra ,  Theodorus Marinus Modderman ,  Johannes Catharinus Hubertus Mulkens ,  Roelof Aeilko Siebrand Ritsema ,  Klaus Simon ,  Joannes Theodoor De Smit ,  Alexander Straaijer ,  Bob Streefkerk ,  Helmar Van Santen ,  Sjoerd Nicolaas Lambertus Donders

发明人： Joeri Lof ,  Antonius Theodorus Anna Maria Derksen ,  Christiaan Alexander Hoogendam ,  Aleksey Kolesnychenko ,  Erik Roelof Loopstra ,  Theodorus Marinus Modderman ,  Johannes Catharinus Hubertus Mulkens ,  Roelof Aeilko Siebrand Ritsema ,  Klaus Simon ,  Joannes Theodoor De Smit ,  Alexander Straaijer ,  Bob Streefkerk ,  Helmar Van Santen ,  Sjoerd Nicolaas Lambertus Donders

IPC分类号： G03B27/42

CPC分类号： G03F7/70341 ,  G03F7/707 ,  G03F7/7085 ,  G03F9/7088

摘要： In a lithographic projection apparatus, a structure surrounds a space between the projection system and a substrate table of the lithographic projection apparatus. Gas is used between the structure and the surface of the substrate to contain liquid in the space.

摘要翻译： 在光刻投影装置中，结构围绕投影系统与光刻投影装置的基板台之间的空间。 在结构和衬底的表面之间使用气体以在空间中容纳液体。

公开(公告)号：US08094311B2

公开(公告)日：2012-01-10

申请号：US11912342

申请日：2006-04-26

申请人： Natallia Uzunbajakava ,  Aleksey Kolesnychenko ,  Antonius Theodorus Martinus Van Gogh ,  Gert 'T Hooft ,  Frank Jeroen Pieter Schuurmans

发明人： Natallia Uzunbajakava ,  Aleksey Kolesnychenko ,  Antonius Theodorus Martinus Van Gogh ,  Gert 'T Hooft ,  Frank Jeroen Pieter Schuurmans

IPC分类号： G01N21/31

CPC分类号： G01J3/32 ,  G01J3/02 ,  G01J3/0213 ,  G01J3/0229 ,  G01J3/0264 ,  G01J3/0272 ,  G01J3/28 ,  G01J2003/1282 ,  G01N21/274

摘要： The invention relates to a multivariate calibration which can be used when the optical system used for that method does not comprise a multi-channel detector such as a CCD sensor or a line array of photodiodes. An optical system without a multi-channel detector doesn't allow to carry out preprocessing steps. Thus there is the need to carry out these preprocessing steps in another way. It is suggested to partially replace the preprocessing step by a measurement of the optical signal, whereby the measurement comprises transmitting or reflecting the optical signal by an optical element, thereby weighing the optical signal by a spectral weighing function. The advantage of the invention is to teach how such an optical system without a bulky and expensive CCD sensor can be used to carry out a multivariate calibration and preprocessing steps.

摘要翻译： 本发明涉及当用于该方法的光学系统不包括诸如CCD传感器或光电二极管的线阵列的多通道检测器时可以使用的多变量校准。 没有多通道检测器的光学系统不允许执行预处理步骤。 因此，需要以另一种方式执行这些预处理步骤。 建议通过光信号的测量部分地代替预处理步骤，由此测量包括通过光学元件发送或反射光信号，从而通过光谱称重功能称量光信号。 本发明的优点是教导如何不使用庞大且昂贵的CCD传感器的这种光学系统来执行多变量校准和预处理步骤。

公开(公告)号：US20100182576A1

公开(公告)日：2010-07-22

申请号：US12727456

申请日：2010-03-19

申请人： Helmar VAN SANTEN ,  Aleksey Kolesnychenko

发明人： Helmar VAN SANTEN ,  Aleksey Kolesnychenko

IPC分类号： G03B27/52

CPC分类号： G03F7/70866 ,  G03F7/70341

摘要： A liquid supply system for an immersion lithographic projection apparatus is disclosed in which a space is defined between the projection system, a barrier member and a substrate. The barrier member is not sealed such that, during use, immersion liquid is allowed to flow out the space and between the barrier member and the substrate.

摘要翻译： 公开了一种用于浸没式光刻投影装置的液体供应系统，其中在投影系统，阻挡构件和基板之间限定空间。 阻挡构件不被密封，使得在使用期间，允许浸没液体流出空间以及阻挡构件和基底之间。

公开(公告)号：US07593093B2

公开(公告)日：2009-09-22

申请号：US11710408

申请日：2007-02-26

申请人： Joeri Lof ,  Hans Butler ,  Sjoerd Nicolaas Lambertus Donders ,  Aleksey Kolesnychenko ,  Erik Roelof Loopstra ,  Hendricus Johannes Maria Meijer ,  Jeroen Johannes Sophia Maria Mertens ,  Johannes Catharinus Hubertus Mulkens ,  Roelof Aeilko Siebrand Ritsema ,  Frank Van Schaik ,  Timotheus Franciscus Sengers ,  Klaus Simon ,  Joannes Theodoor De Smit ,  Alexander Straaijer ,  Helmar Van Santen

发明人： Joeri Lof ,  Hans Butler ,  Sjoerd Nicolaas Lambertus Donders ,  Aleksey Kolesnychenko ,  Erik Roelof Loopstra ,  Hendricus Johannes Maria Meijer ,  Jeroen Johannes Sophia Maria Mertens ,  Johannes Catharinus Hubertus Mulkens ,  Roelof Aeilko Siebrand Ritsema ,  Frank Van Schaik ,  Timotheus Franciscus Sengers ,  Klaus Simon ,  Joannes Theodoor De Smit ,  Alexander Straaijer ,  Helmar Van Santen

IPC分类号： G03B27/42 ,  G03B27/52

CPC分类号： G03F7/70341 ,  G03F7/707 ,  G03F7/7085 ,  G03F7/70866

摘要： A lithographic projection apparatus is disclosed in which a space between the projection system and the substrate is filled with a liquid. An edge seal member at least partly surrounds the substrate or other object on a substrate table to prevent liquid loss when edge portions of the substrate or other object are, for example, imaged or illuminated.