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公开(公告)号：US11555076B2
公开(公告)日：2023-01-17
申请号：US16345619
申请日：2017-10-27
Applicant: Genentech, Inc.
Inventor： Twyla Noelle Lombana , Christoph Spiess , Jeong Kim , Evangeline Toy , Jill Schartner , Zhengmao Ye , Jack Bevers, III , Ryan Cook , Marissa Matsumoto , Amy Berkley
Abstract: The invention provides anti-MIC antibodies and methods of using the same.
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公开(公告)号：US20200308304A1
公开(公告)日：2020-10-01
申请号：US16852136
申请日：2020-04-17
Applicant: GENENTECH, INC.
Inventor： Yu-Ju G. Meng , Hok Seon Kim , Ingrid Kim , Christoph Spiess
IPC: C07K16/42
Abstract: The instant disclosure provides antibody fragments (e.g., Fab and F(ab′)2) having reduced or no reactivity towards pre-existing anti-hinge antibodies (AHA) and compositions comprising such antibody fragments, as well as methods of making and using such antibody fragments and compositions.
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公开(公告)号：US10323094B2
公开(公告)日：2019-06-18
申请号：US15184690
申请日：2016-06-16
Applicant: Genentech, Inc.
Inventor： Isidro Hotzel , Teemu T. Junttila , Ji Li , Justin Scheer , Danielle DiCara , Diego Ellerman , Christoph Spiess , Paul J. Carter
IPC: C07K16/00 , C12P21/08 , A61K39/395 , A61K39/40 , A61K39/42 , C07K16/28 , A61K45/06 , C07K16/30 , G01N33/574 , A61K47/68 , A61K39/00
Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.
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公开(公告)号：US11845799B2
公开(公告)日：2023-12-19
申请号：US17119753
申请日：2020-12-11
Applicant: Genentech, Inc.
Inventor： WeiYu Lin , Christoph Spiess , Liping Sun , Yan Wu , Cecilia P. C. Chiu , Walter Christian Darbonne , Michael Andrew Dillon
CPC classification number: C07K16/2824 , C07K16/2809 , A61K2039/507 , C07K2317/565 , C07K2317/567 , C07K2317/92
Abstract: Provided herein are anti-Ly6G6D (lymphocyte antigen 6 complex, locus G61) antibodies and methods of using the same.
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公开(公告)号：US11192950B2
公开(公告)日：2021-12-07
申请号：US16395009
申请日：2019-04-25
Applicant: Genentech, Inc.
Inventor： Isidro Hotzel , Teemu T. Junttila , Ji Li , Justin Scheer , Danielle Dicara , Diego Ellerman , Christoph Spiess , Paul J. Carter
IPC: C07H21/02 , C07H21/04 , C12P21/06 , C12P21/04 , C12N5/00 , C12N5/16 , C12N1/20 , C07K16/28 , A61K47/68 , A61K39/395 , A61K45/06 , C07K16/30 , G01N33/574 , C07K16/00 , A61K39/00
Abstract: The present invention relates to anti-FcRH5 antibodies, including anti-FcRH5 antibodies comprising an FcRH5 binding domain and a CD3 binding domain (e.g., FcRH5 T cell-dependent bispecific (TDB) antibodies), and methods of using the same.
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Patent Agency Ranking
公开(公告)号：US10246518B2
公开(公告)日：2019-04-02
申请号：US15837801
申请日：2017-12-11
Applicant: Genentech, Inc.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号：US09884919B2
公开(公告)日：2018-02-06
申请号：US15214160
申请日：2016-07-19
Applicant: GENENTECH, INC.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
IPC: A61K39/395 , C07K16/40 , C07K14/71 , C07K16/28 , A61K39/00
CPC classification number: C07K16/40 , A61K2039/505 , C07K14/71 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/75 , C07K2317/92
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号：US09873748B2
公开(公告)日：2018-01-23
申请号：US14582100
申请日：2014-12-23
Applicant: GENENTECH, INC.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
CPC classification number: C07K16/40 , A61K2039/505 , C07K14/71 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/75 , C07K2317/92
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号：US20160319038A1
公开(公告)日：2016-11-03
申请号：US15214160
申请日：2016-07-19
Applicant: GENENTECH, INC.
Inventor： YONGMEI CHEN , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
CPC classification number: C07K16/40 , A61K2039/505 , C07K14/71 , C07K16/2863 , C07K2317/21 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/40 , C07K2317/41 , C07K2317/51 , C07K2317/515 , C07K2317/524 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/71 , C07K2317/75 , C07K2317/92
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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公开(公告)号：US20240026033A1
公开(公告)日：2024-01-25
申请号：US18194276
申请日：2023-03-31
Applicant: Genentech, Inc.
Inventor： Yongmei Chen , James Ernst , Hok Seon Kim , Junichiro Sonoda , Christoph Spiess , Scott Stawicki , Yan Wu
CPC classification number: C07K16/40 , C07K14/71 , C07K16/2863 , C07K2317/24 , C07K2317/31 , C07K2317/33 , C07K2317/34 , C07K2317/75 , C07K2317/92 , C07K2317/40 , C07K2317/41 , C07K2317/524 , C07K2317/567 , C07K2317/71 , A61K2039/505
Abstract: The presently disclosed subject matter provides antibodies that bind KLB and FGFR1, and methods of using the same. In certain embodiments, an antibody of the present disclosure includes a bispecific antibody that binds to an epitope present on FGFR1 and binds to an epitope present on KLB.
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