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公开(公告)号:US20230347025A1
公开(公告)日:2023-11-02
申请号:US18348247
申请日:2023-07-06
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
Inventor: Myoung-Ryul OK , Jimin PARK , Yu Chan KIM , Hyun Kwang SEOK , Hyung-Seop HAN , Hojeong JEON , Hyunseon SEO , Jee-Wook LEE , Jin Kyung JEON , Gayoung JUNG , Jong Woong PARK , Ji Hun PARK
CPC classification number: A61L31/16 , A61B17/8605 , A61B17/80 , A61K9/0024 , A61K33/00 , A61L31/022 , F16B35/04 , A61F2/2846 , A61B17/866 , A61B2017/00893
Abstract: Provided is an implant having a controlled generation rate of reactive oxygen species and a method of controlling generation of reactive oxygen species using the same. The implant having a controlled generation rate of reactive oxygen species according to the present invention includes a body formed of a metallic material and having a groove, a first filling metal filling one region of the groove, and a second filling metal filling the groove on the first filling metal, wherein the second filling metal has an ionization tendency different from that of the first filling metal.
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公开(公告)号:US20200071834A1
公开(公告)日:2020-03-05
申请号:US16555079
申请日:2019-08-29
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor: Hojeong JEON , Seung Hoon UM , Yongwoo CHUNG , Hyunseon SEO , Yu Chan KIM , Myoung-Ryul OK , Hyun Kwang SEOK
Abstract: Provided is a method of forming an apatite coating, including brining an apatite-forming precursor solution including Ca2+ ions and PO43− ions into direct contact with at least one region of the substrate, emitting a laser beam onto the region of the substrate in direct contact with the precursor solution through the precursor solution, and forming apatite on the region onto which the laser beam is emitted.
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公开(公告)号:US20210309521A1
公开(公告)日:2021-10-07
申请号:US17130536
申请日:2020-12-22
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor: Hojeong JEON , Seung Hoon UM , Yu Chan KIM , Hyung-Seop HAN , Myoung-Ryul OK , Hyunseon SEO , Hyun Kwang SEOK
IPC: C01B25/32 , B23K26/122
Abstract: Provided is a method of synthesizing apatite powder by emitting a laser beam to a surface of a substrate immersed in a precursor solution. The method is including immersing a substrate in an apatite-forming precursor solution, emitting a laser beam to a region on a surface of the substrate immersed in the precursor solution, and obtaining apatite powder generated in the precursor solution.
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公开(公告)号:US20200208254A1
公开(公告)日:2020-07-02
申请号:US16691613
申请日:2019-11-22
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor: Yu Chan KIM , Hyun Kwang SEOK , SEUNG HEE HAN , Hojeong JEON , Myoung-Ryul OK , Hyunseon SEO , Kyoung Won PARK , Yeon Wook JUNG , Pil Ryung CHA
Abstract: Provided is a method of increasing corrosion resistance of a magnesium (Mg) member. The method includes preparing a Mg member, and ion-implanting a doping element into a surface of the Mg member. Herein, the doping element includes an element capable of increasing a Fermi energy level of magnesium oxide (MgO) when doped on MgO.
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公开(公告)号:US20210381112A1
公开(公告)日:2021-12-09
申请号:US17338110
申请日:2021-06-03
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor: Hojeong JEON , Seung Hoon UM , Jae Ho PARK , Justin Jihong CHUNG , Hyunseon SEO , Hyung-Seop HAN , Yu Chan KIM , Myoung-Ryul OK , Hyun Kwang SEOK
IPC: C23C26/00 , B23K26/122 , B23K26/352 , C01B25/32
Abstract: Provided is a method of forming an apatite coating, the method including immersing a substrate in an apatite-forming precursor solution including Ca2+ ions and PO43− ions, emitting a laser beam onto a surface of the substrate immersed in the precursor solution, and forming an apatite coating in a region exposed to the laser beam, wherein an output power of the laser beam is set within a range enabling the surface of the substrate to be melted.
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公开(公告)号:US20200345479A1
公开(公告)日:2020-11-05
申请号:US16836925
申请日:2020-04-01
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor: Hojeong JEON , Myoung-Ryul OK , Yu Chan KIM , Hyun Kwang SEOK
IPC: A61F2/16
Abstract: Provided is an intraocular lens including: an optic portion; and a haptic portion extending from the optic portion, wherein a pattern having ridges and grooves is formed on at least one of the optic portion and the haptic portion, and each of the grooves has a nanostructure roughness. Provided also is a method of manufacturing an intraocular lens, the method including: seating an object to be processed including an optic portion and at least one haptic portion extending from the optic portion, processing a predetermined pattern for guiding cells by performing laser irradiation on the haptic portion and the optic portion, forming grooves having a nanostructure surface roughness in the predetermined pattern formed by laser beams, and the surface of each of the grooves has an average roughness Ra less than 200 nm.
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公开(公告)号:US20160095698A1
公开(公告)日:2016-04-07
申请号:US14744190
申请日:2015-06-19
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor: Hojeong JEON , Chunga KWON , Yu Chan KIM , Hyun Kwang SEOK , Jee-Wook LEE , Hyun Soo LEE , Choun Ki JOO
IPC: A61F2/16
CPC classification number: A61F2/16 , A61F2002/0081 , A61F2002/009 , A61F2002/1681
Abstract: Disclosed is an intraocular lens with a fine pattern including an optic having a circular shape, and a plurality of haptics connected to a periphery of the optic, and a pattern is formed on a surface of a partial area of at least one of the optic and the haptics.
Abstract translation: 公开了具有包括圆形形状的光学元件的精细图案的眼内透镜和连接到光学元件的周边的多个触觉件,并且在光学元件和光学元件中的至少一个的局部区域的表面上形成图案, 触觉。
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公开(公告)号:US20210220631A1
公开(公告)日:2021-07-22
申请号:US17153969
申请日:2021-01-21
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY , Industry-University Cooperation Foundation Hanyang University ERICA Campus
Inventor: Myoung-Ryul OK , So Yeon KIM , Yoon Ki JOUNG , Yu Chan KIM , Hyun Kwang SEOK , Hyung-Seop HAN , Hojeong JEON , Hyunseon SEO , Inho KIM , Kyoung Won PARK , Yongwoo CHUNG , Jaekyun KIM
Abstract: Provided are phototherapeutic needle patches usable for phototherapy by using needle patches capable of injecting drugs or cosmetic substances to patients, and methods of manufacturing the same. A phototherapeutic needle patch may include a patch body attachable to skin of a patient, at least one microneedle protruding from the patch body, one end of the microneedle configured to deliver a drug through stratum corneum of the skin to inner tissues of the skin, and light grooves formed in a concave shape along a length direction of the microneedle in such a manner that therapeutic light radiated from a light source for phototherapy easily penetrates into the skin along the microneedle.
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公开(公告)号:US20200326457A1
公开(公告)日:2020-10-15
申请号:US16838030
申请日:2020-04-02
Applicant: Korea Institute of Science and Technology , Korea University Research and Business Foundation
Inventor: Hojeong JEON , Jungmok SEO , Yeon Taek LEE , Seung Hoon LEE , Seung No HONG
Abstract: Provided is a lens for a medical device. The lens includes a microstructural layer on a surface of the lens, and a coating layer on the microstructural layer. The coating layer is made of a self-assembled monolayer (SAM). Also provided is a method of manufacturing a lens for a medical device. The method includes forming a microstructural layer on a surface of the lens; and forming a coating layer on the surface on which the microstructure is formed. The coating layer is made of a self-assembled monolayer (SAM).
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公开(公告)号:US20180238780A1
公开(公告)日:2018-08-23
申请号:US15753115
申请日:2016-08-24
Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
Inventor: Hojeong JEON , Indong JUN , Kangwon LEE , Hyung-Seop HAN , Jimin PARK , Myoung-Ryul OK , Yu Chan KIM , Hyun Kwang SEOK
CPC classification number: G01N1/31 , B01J19/0046 , B01J2219/00382 , B01J2219/0043 , B01J2219/00743 , B82Y40/00 , C12N5/0068 , C12N2533/74 , C12N2535/10 , G01N1/30 , G01N33/5005
Abstract: A cell patterning material, a method of preparing the cell patterning material, a cell patterning method using the cell patterning material, and a biosensor including patterned cells obtained by using the cell patterning method are provided. According to the present disclosure, cells may be conveniently and efficiently patterned and the time for applying external stimulation for patterning may be controlled. In addition, the patterned cells may have an excellent proliferation rate and excellent differentiation efficiency, and may be re-patterned in a different direction, and High-throughput screening using the patterned cells is possible.
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