公开(公告)号：US11213821B2

公开(公告)日：2022-01-04

申请号：US16323163

申请日：2017-04-10

Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION

Inventor： Chae Seung Lim ,  Jeong Hun Nam

IPC: B01L3/00

Abstract: The present invention relates to a microfluidic device and a manufacturing method therefore and, more particularly, to a microfluidic device comprising: a first substrate layer; a second substrate layer formed on at least one surface of the first substrate layer; and a plurality of transducers formed on the surface of the first substrate layer and embedded in the second substrate layer, wherein the transducer comprises a conductive microfluidic channel. The present invention can provide an elastic wave substrate microfluidic device capable of controlling an elastic wave according to a property of a microparticle and capable of being manufactured without expensive equipment and complicated process procedures.

公开(公告)号：US09927425B2

公开(公告)日：2018-03-27

申请号：US14758291

申请日：2013-12-27

Applicant: Korea University Research and Business Foundation

Inventor： Se Hyun Shin ,  Chae Seung Lim ,  Jeong Hoon Nam ,  Hyun Jung Lim

IPC: G01N33/86 ,  G01N33/50 ,  G01N33/49 ,  B01L3/00 ,  B01F13/00 ,  B01F13/08 ,  B01F15/02 ,  G01N35/00

CPC classification number: G01N33/5029 ,  B01F13/0059 ,  B01F13/0818 ,  B01F15/0233 ,  B01L3/502746 ,  B01L2300/0803 ,  B01L2300/087 ,  B01L2300/0883 ,  B01L2400/0409 ,  B01L2400/0677 ,  G01N33/491 ,  G01N33/5044 ,  G01N35/00069 ,  G01N2035/00237

Abstract: The present invention relates to an apparatus and method for testing a multi-function and a drug response of platelet based on a centrifugal microfluidics. The testing apparatus according to the present invention may include: a rotatable disk; a sample chamber arranged at the center of the disk such that a blood sample is accommodated therein; stirring chambers respectively connected to the sample chamber in multiple radial directions so as to introduce a shear flow in the blood sample; microchannels connected to the stirring chambers such that adhesion and cohesion of platelets occur during the movement of the blood sample; and a waste sample chamber in which the blood sample is accommodated after passing through the microchannels. According to the present invention, multiple drug tests can be performed on a single blood sample at one time in multiple channels such that multiple tests is possible with respect to complex platelet functions, and thus testing time is reduced and testing costs can be saved.

公开(公告)号：US09983220B2

公开(公告)日：2018-05-29

申请号：US14655437

申请日：2013-12-26

Applicant: Korea University Research and Business Foundation

Inventor： Se Hyun Shin ,  Chae Seung Lim

IPC: G01N33/86 ,  G01N33/49 ,  G01N15/14 ,  B01L3/00 ,  G01N15/06 ,  C12M3/00 ,  G01N15/00

CPC classification number: G01N33/86 ,  B01L3/502715 ,  B01L3/50273 ,  B01L2200/10 ,  B01L2300/0627 ,  B01L2300/0645 ,  B01L2300/0654 ,  B01L2300/0663 ,  B01L2400/0406 ,  B01L2400/0478 ,  B01L2400/06 ,  G01N15/0612 ,  G01N15/1463 ,  G01N15/1484 ,  G01N33/49 ,  G01N2015/0092

Abstract: The present invention relates to an apparatus and a method for testing a function and a drug response of a platelet based on a microfluidic chip. The apparatus for test comprises a measuring device containing a blood sample and measuring aggregation and adhesion of a platelet generated by flow of the blood sample; and a fluid driving device which is connected to the measuring device and generates a oscillating shear flow of the blood sample. Therefore, activation of factors such as a platelet and von Willebrand factor (vWF) etc. can be activated uniformly and completely, and a repeatability of the platelet aggregation can be increased.

公开(公告)号：USD1049373S1

公开(公告)日：2024-10-29

申请号：US29890429

申请日：2023-04-24

Applicant: Korea University Research and Business Foundation

Designer： Chae Seung Lim ,  Woong Sik Jang ,  Hyun-Seul Jee

Abstract: FIG. 1 is a front, top, and right side perspective view of a needle for diagnostic kit;
FIG. 2 is a rear, top, and left side perspective view of the needle for diagnostic kit of FIG. 1.
FIG. 3 is a front elevational view of the needle for diagnostic kit of FIG. 1;
FIG. 4 is a rear elevational view of the needle for diagnostic kit of FIG. 1;
FIG. 5 is a left side elevational view of the needle for diagnostic kit of FIG. 1;
FIG. 6 is a right side elevational view of the needle for diagnostic kit of FIG. 1;
FIG. 7 is a top plan view of the the needle for diagnostic kit of FIG. 1; and,
FIG. 8 is a bottom plan view of the needle for diagnostic kit of FIG. 1.
The broken lines in the drawings are for the purpose of illustrating portions of the needle for diagnostic kit that form no part of the claimed design.