Biological analysis systems, devices, and methods

    公开(公告)号:US11371093B2

    公开(公告)日:2022-06-28

    申请号:US16246990

    申请日:2019-01-14

    摘要: A device for performing biological sample reactions may include a plurality of flow cells configured to be mounted to a common microscope translation stage, wherein each flow cell is configured to receive at least one sample holder containing biological sample. Each flow cell also may be configured to be selectively placed in an open position for positioning the at least one sample holder into the flow cell and a closed position for reacting biological sample contained in the at least one sample holder. The plurality of flow cells may be configured to be selectively placed in the open position and the closed position independently of each other.

    Pattern forming apparatus and article manufacturing method

    公开(公告)号:US10747116B2

    公开(公告)日:2020-08-18

    申请号:US16292953

    申请日:2019-03-05

    IPC分类号: G03B27/42 G03F7/20 G03F9/00

    摘要: There is provided a pattern forming apparatus including a holding unit configured to suction and hold a substrate, and an optical system configured to detect, from a suction surface side of the substrate, an alignment mark formed on the substrate held by the holding unit. The pattern forming apparatus is provided with a wavelength separation element for performing wavelength separation between pattern forming light for forming a pattern on the substrate and alignment mark detection light for detecting the alignment mark.

    Magnification compensation and/or beam steering in optical systems

    公开(公告)号:US10539770B2

    公开(公告)日:2020-01-21

    申请号:US16011564

    申请日:2018-06-18

    摘要: Techniques are disclosed for magnification compensation and/or beam steering in optical systems. An optical system may include a lens system to receive first radiation associated with an object and direct second radiation associated with an image of the object toward an image plane. The lens system may include a set of lenses, and an actuator system to selectively adjust the set of lenses to adjust a magnification associated with the image symmetrically along a first and a second direction. The lens system may also include a beam steering lens to direct the first radiation to provide the second radiation. In some examples, the lens system may also include a second set of lenses, where the actuator system may also selectively adjust the second set of lenses to adjust the magnification along the first or the second direction. Related methods are also disclosed.

    Active metrology frame and thermal frame temperature control in imprint lithography

    公开(公告)号:US10444624B1

    公开(公告)日:2019-10-15

    申请号:US16206642

    申请日:2018-11-30

    摘要: A thermal frame of an imprinting apparatus has an motor and a cooling element. A metrology frame of the imprinting apparatus is coupled to an output end of the motor and receives an imprinting mold. Thermal isolation is provided between the motor and the metrology frame. Thermal sensors are disposed at locations of the frames. A digital controller applies a control signal for controlling a driving signal of the cooling element to maintain a thermal balance, such as thermal equilibrium, of heat flow between the frames. The digital controller uses output of the thermal sensors to identify transfer functions of heat flow used to calculate the control signal. The feedforward design avoids the very low control bandwidth that limits the performance of typical feedback designs.