公开(公告)号：US20060220096A1

公开(公告)日：2006-10-05

申请号：US11133718

申请日：2005-05-19

Applicant: Bin Wang ,  Yanjun Ma

Inventor： Bin Wang ,  Yanjun Ma

IPC: H01L29/788

CPC classification number: G11C16/045 ,  G11C16/0416 ,  G11C16/0441 ,  G11C2216/10 ,  H01L27/115 ,  H01L27/11521 ,  H01L27/11558 ,  H01L29/42324 ,  H01L29/7883

Abstract: Tunneling-enhanced, floating gate semiconductor devices and methods for forming such devices are described. In one embodiment, a p-n junction device is formed with a floating gate that is partially doped with n- and p-type impurities. Two regions on either side of an n+ doped region in the floating gate and a surface region on a substrate are implanted with the impurities based on a number of predetermined configurations. In another embodiment, a transistor type semiconductor device is configured with implanted impurities in two regions of its floating gate as well as two surface regions in its substrate. Enhanced tunneling junction enables use of lower tunneling voltages in applications such as programming NVM cells.

Abstract translation: 描述了隧道增强型浮栅半导体器件及其形成方法。 在一个实施例中，p-n结器件形成有部分掺杂有n型和p型杂质的浮栅。 基于多个预定配置，在浮置栅极中的n +掺杂区域的任一侧上的两个区域和衬底上的表面区域注入杂质。 在另一个实施例中，晶体管型半导体器件被配置为在其浮动栅极的两个区域中具有注入的杂质以及其衬底中的两个表面区域。 增强的隧道结使得能够在诸如编程NVM单元之类的应用中使用较低的隧道电压。

公开(公告)号：US20050175606A1

公开(公告)日：2005-08-11

申请号：US10474345

申请日：2002-04-10

Applicant: Hua-Liang Huang ,  Ju-Long Cheng ,  Xiang-Bin Wang ,  Li-Ping Song ,  Zhong Zhang ,  Qing Lin ,  Ying Gu

Inventor： Hua-Liang Huang ,  Ju-Long Cheng ,  Xiang-Bin Wang ,  Li-Ping Song ,  Zhong Zhang ,  Qing Lin ,  Ying Gu

IPC: C12N15/09 ,  A61K39/395 ,  A61P35/00 ,  C07K7/64 ,  C07K16/18 ,  C07K16/28 ,  C07K16/30 ,  C07K16/32 ,  C07K19/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N15/13 ,  C12N15/63

CPC classification number: C07K16/30 ,  A61K2039/505 ,  C07K16/2809 ,  C07K16/2818 ,  C07K2317/31 ,  C07K2317/55

Abstract: The invention provides a cyclic single-chain trispecific antibody against human tumor. It comprises three parts. The first part is an anti-tumor Fab antibody, an anti-tumor single-domain antibody or an scFv. The second part is a reshaped Fab antibody against human CD3, a reshaped single-domain antibody against human CD3 or a reshaped scFv against human CD3. The third part is a reshaped Fab antibody against human CD28, a reshaped single-domain antibody against human CD28 or a reshaped scFv against human CD28. The present invention also offers the DNA sequence coding for this trispecific antibody, expression vectors containing this DNA sequence and host cells (E. coli) containing the vectors.

Abstract translation: 本发明提供了抗人肿瘤的环状单链三特异性抗体。 它包括三部分。 第一部分是抗肿瘤Fab抗体，抗肿瘤单结构域抗体或scFv。 第二部分是针对人CD3的重塑Fab抗体，针对人CD3的重构单域抗体或针对人CD3的重构scFv。 第三部分是针对人CD28的重塑Fab抗体，针对人CD28的重构单结构域抗体或针对人CD28的重构scFv。 本发明还提供编码该三特异性抗体的DNA序列，含有该DNA序列的表达载体和含有该载体的宿主细胞（大肠杆菌）。

公开(公告)号：US20050130954A1

公开(公告)日：2005-06-16

申请号：US10993173

申请日：2004-11-19

Applicant: Ian Mitchell ,  Keith Spencer ,  Peter Stengel ,  Yongxin Han ,  Nicholas Kallan ,  Mark Munson ,  Guy Vigers ,  James Blake ,  Anthony Piscopio ,  John Josey ,  Scott Miller ,  Dengming Xiao ,  Riu Xu ,  Chang Rao ,  Bin Wang ,  April Bernacki

Inventor： Ian Mitchell ,  Keith Spencer ,  Peter Stengel ,  Yongxin Han ,  Nicholas Kallan ,  Mark Munson ,  Guy Vigers ,  James Blake ,  Anthony Piscopio ,  John Josey ,  Scott Miller ,  Dengming Xiao ,  Riu Xu ,  Chang Rao ,  Bin Wang ,  April Bernacki

IPC: A61K20060101 ,  A61K31/496 ,  A61K31/519 ,  A61K31/53

CPC classification number: C07D239/94 ,  B41M3/008 ,  B44F1/10 ,  C07D231/56 ,  C07D237/28 ,  C07D239/42 ,  C07D239/47 ,  C07D239/48 ,  C07D401/04 ,  C07D401/12 ,  C07D403/04 ,  C07D403/12 ,  C07D409/04 ,  C07D409/12 ,  C07D471/04 ,  C07D487/04 ,  C07D491/048 ,  C07D495/04 ,  G09F13/16 ,  Y10T428/24802 ,  Y10T428/24851 ,  Y10T428/25 ,  Y10T428/31507 ,  Y10T428/31551 ,  Y10T428/31786 ,  Y10T428/31855

Abstract: The present invention provides compounds, including resolved enantiomers, diastereomers, solvates and pharmaceutically acceptable salts thereof, comprising the Formula: A-L-CR where CR is a cyclical core group, L is a linking group and A is as defined herein. Also provided are methods of using the compounds of this invention as AKT protein kinase inhibitors and for the treatment of hyperproliferative diseases such as cancer.

Abstract translation: 本发明提供包括拆分的对映异构体，非对映异构体，溶剂合物和药学上可接受的盐的化合物，其包含式：<？在线公式描述=“在线公式”end =“lead”→> AL-CR < in-line-formula description =“In-line Formulas”end =“tail”？>其中CR是循环核心组，L是连接组，A如本文所定义。 还提供了使用本发明化合物作为AKT蛋白激酶抑制剂和治疗过度增殖性疾病如癌症的方法。

公开(公告)号：US20050126709A1

公开(公告)日：2005-06-16

申请号：US10937905

申请日：2004-09-10

Applicant: Naoki Takayama ,  Bin Wang ,  Satoshi Harada

Inventor： Naoki Takayama ,  Bin Wang ,  Satoshi Harada

IPC: H01L21/00 ,  C23F1/00

CPC classification number: H01L21/67253

Abstract: With analysis data in the prior art, it is difficult to find out if a change regarded as a judgmental standard of the completion of seasoning has come from a change due to the seasoning, namely, change in condition of the interior of a processing container or come from another change based on a temperature change among respective dummy wafers and furthermore, it is difficult to judge whether the seasoning has been completed or not. Therefore, a plasma processing method of the present invention, which is a method for detecting the completion of seasoning in performing the seasoning by loading dummy wafers W into a processing container 2 of a plasma processing apparatus 1, includes a process of creating a predictive formula for predicting the completion of seasoning and another process of detecting the completion of seasoning in performing the seasoning, based on the predictive formula. The creation of the predictive formula is accomplished by performing a multivariate analysis against a plurality of measured data that can be obtained by first supplying dummy wafers W into the processing container 2, cooling down the interior of the processing container 2 and supplying a plurality of dummy wafers W into the processing container 2 again.

Abstract translation: 通过现有技术的分析数据，难以确定作为调味品完成的判断标准的变化是否来自调味品的变化，即处理容器的内部状况的变化或 来自基于各个虚拟晶片之间的温度变化的另一变化，此外，难以判断调味是否已经完成。 因此，本发明的等离子体处理方法是通过将虚拟晶片W装载到等离子体处理装置1的处理容器2中来进行调味的完成调查的方法，包括：生成预测式 根据预测公式预测调味料的完成情况和进行调味料调查完成情况的另一个过程。 通过对多个测量数据执行多变量分析来实现预测公式的创建，该多个测量数据可以通过首先将虚拟晶片W提供到处理容器2中，冷却处理容器2的内部并提供多个虚拟 晶片W再次进入处理容器2。

公开(公告)号：US06693268B2

公开(公告)日：2004-02-17

申请号：US09960664

申请日：2001-09-24

Applicant: Cheng-Bin Wang

Inventor： Cheng-Bin Wang

IPC: H01L2715

CPC classification number: H01S5/0264 ,  G01J1/32 ,  G01J1/42 ,  H01S5/0683 ,  H01S5/183

Abstract: An auto feedback and photo attenuation structure of a vertical cavity surface emitting laser (VCSEL) includes a VCSEL combined with a monitor photodetector (MPD). The thickness of the absorbing layer of the MPD may be adjusted, so that when output light of different wavelengths passes through the MPD, a portion of light may be absorbed by the absorbing layer to function as a feedback path of an auto power control, and a portion of light may penetrate through the absorbing layer, and may satisfy the requirement of the eye safety class I. The thickness of the absorbing layer of the MPD may be controlled precisely, thereby increasing the quality of products and decreasing cost of fabrication.

Abstract translation: 垂直腔表面发射激光器（VCSEL）的自动反馈和光衰减结构包括与监视器光电检测器（MPD）组合的VCSEL。 可以调节MPD的吸收层的厚度，使得当不同波长的输出光通过MPD时，一部分光可以被吸收层吸收，用作自动功率控制的反馈路径，并且 一部分光可以穿透吸收层，并且可以满足眼睛安全等级I的要求。可以精确地控制MPD的吸收层的厚度，从而提高产品的质量并降低制造成本。

公开(公告)号：US06543015B1

公开(公告)日：2003-04-01

申请号：US09336785

申请日：1999-06-21

Applicant: Gyh-Bin Wang ,  Der-Min Yuan

Inventor： Gyh-Bin Wang ,  Der-Min Yuan

IPC: G06F1100

CPC classification number: G11C29/40

Abstract: In this invention two compression circuits are combined to produce at a single output pass/fail condition for a plurality of memory addresses and a plurality of I/O. The output of an address compression circuit is connected to an I/O circuit. An I/O compression circuit is connected to several I/O circuits and the output of the I/O compression circuit controls a selected data output driver to provide a combined test result of the plurality of addresses and the plurality of I/O. The combination of the two compression circuits is made possible because the address data compression circuits and the I/O compression circuits use different truth tables.

Abstract translation: 在本发明中，两个压缩电路被组合以产生用于多个存储器地址和多个I / O的单个输出通过/失败条件。 地址压缩电路的输出连接到I / O电路。 I / O压缩电路连接到多个I / O电路，I / O压缩电路的输出控制所选择的数据输出驱动器，以提供多个地址和多个I / O的组合测试结果。 两个压缩电路的组合是可能的，因为地址数据压缩电路和I / O压缩电路使用不同的真值表。

公开(公告)号：US06097799A

公开(公告)日：2000-08-01

申请号：US120400

申请日：1998-07-22

Applicant: Hsiu-Bin Wang

Inventor： Hsiu-Bin Wang

IPC: H04M1/18 ,  H04M1/00

CPC classification number: H04M1/18

Abstract: A pay phone box structure includes a casing having a first side wall and a second side wall, a first supporting plate fixedly mounted on the first side wall of the casing and containing a plurality of first locking slots, a second supporting plate fixedly mounted on the second side wall of the casing and containing a plurality of second locking slots, a suspension bar secured to the second supporting plate and having a plurality of first locking hooks each detachably received in thesecond locking slots, a pivot plate pivotally mounted on the suspension bar and having an upper end portion and a lower end portion, a cover pivotally mounted on the casing and having a first side wall, a second side wall secured to the pivot plate, a closed wall and an open wall, a sliding plate slidably mounted on the first side wall of the cover and having a plurality of second locking hooks each detachably received in thefirst locking slots, and a U-shaped pivot bar pivotally mounted on the closed wall of the cover and having a first leg pivotally connected with the sliding plate and a second leg pivotally connected with the lower end portion of the pivot plate.

Abstract translation: 付费电话盒结构包括具有第一侧壁和第二侧壁的壳体，固定地安装在壳体的第一侧壁上并容纳多个第一锁定槽的第一支撑板，固定地安装在壳体上的第二支撑板 壳体的第二侧壁并且包含多个第二锁定槽，悬挂杆固定到第二支撑板并具有多个可拆卸地容纳在第二锁定槽中的第一锁定钩，枢轴安装在悬挂杆上， 具有上端部和下端部，盖枢转地安装在壳体上并具有第一侧壁，固定到枢转板的第二侧壁，闭合壁和开放壁，滑动板可滑动地安装在 盖的第一侧壁，并且具有多个可拆卸地容纳在第一锁定槽中的第二锁定钩，以及可枢转地安装在封闭壁上的U形枢轴 并且具有与滑动板枢转地连接的第一腿和与枢转板的下端部枢转地连接的第二腿。

公开(公告)号：US5999032A

公开(公告)日：1999-12-07

申请号：US35053

申请日：1998-03-05

Applicant: Gyh-Bin Wang ,  Li-Chin Tien

Inventor： Gyh-Bin Wang ,  Li-Chin Tien

IPC: G06F1/10 ,  H03K5/14 ,  H03L7/00

CPC classification number: G06F1/10

Abstract: A dual phase synchronous race delay clock circuit that will create an internal clock signal in an integrated circuit that is synchronized with and has minimum skew from an external system clock signal is disclosed. The synchronous race delay circuit has an input buffer circuit to receive, buffer, and amplify an external clock signal. The input buffer circuit has a delay time that is the first delay time. A fast pulse generator is connected to the input buffer circuit to create a fast pulse signal. The fast pulse generator is connected to a slow pulse generator to create a slow pulse signal. The fast pulse generator and the slow pulse generator is connected to a race delay measurement means to determine a measurement of a period of the external system clock by comparing a time difference between the slow pulse signal and a following fast pulse signal. A delay control means is connected to the race delay measurement means to receive the measurement of the period of the external system clock. The delay control means will create a first phase control pulse and a second phase control pulse. A duty cycle synchronizer means is connected to the delay control means to create the dual phases of the internal clock from the first phase control pulse and the second phase control pulse. An internal buffer will buffer and amplify the two phases of the internal clock signal that is aligned with the external clock signal to have minimum skew.

Abstract translation: 公开了一种双相同步竞争延迟时钟电路，其将在与外部系统时钟信号同步并且具有来自外部系统时钟信号的最小偏移的集成电路中创建内部时钟信号。 同步竞争延迟电路具有用于接收，缓冲和放大外部时钟信号的输入缓冲电路。 输入缓冲电路具有作为第一延迟时间的延迟时间。 快速脉冲发生器连接到输入缓冲电路以产生快速脉冲信号。 快速脉冲发生器连接到慢脉冲发生器以产生慢脉冲信号。 快速脉冲发生器和慢脉冲发生器通过比较慢脉冲信号和随后的快速脉冲信号之间的时间差，连接到比赛延迟测量装置，以确定外部系统时钟周期的测量。 延迟控制装置连接到比赛延迟测量装置以接收外部系统时钟周期的测量。 延迟控制装置将产生第一相位控制脉冲和第二相位控制脉冲。 占空比同步器装置连接到延迟控制装置，以从第一相位控制脉冲和第二相位控制脉冲产生内部时钟的双相位。 内部缓冲器将缓冲和放大与外部时钟信号对准的内部时钟信号的两相，以具有最小的偏移。

公开(公告)号：US5981505A

公开(公告)日：1999-11-09

申请号：US979385

申请日：1997-11-26

Applicant: David B. Weiner ,  William V. Williams ,  Bin Wang

Inventor： David B. Weiner ,  William V. Williams ,  Bin Wang

IPC: A61K39/00 ,  A61K39/21 ,  C07K14/16 ,  C12N15/87 ,  A61K45/05 ,  A61K48/00 ,  A61K31/00

CPC classification number: C07K14/005 ,  A61K39/00 ,  A61K39/12 ,  A61K39/21 ,  C12N15/87 ,  A61K2039/53 ,  A61K2039/545 ,  A61K2039/55566 ,  A61K2039/57 ,  A61K39/0011 ,  C12N2740/16034 ,  C12N2740/16122 ,  C12N2740/16134 ,  C12N2740/16234 ,  C12N2740/16322 ,  Y10S514/818

Abstract: Methods of inducing genetic material into cells of an individual and compositions and kits for practicing the same are disclosed. The methods comprise the steps of contacting cells of an individual with a polynucleotide function enhancer and administering to the cells, a nucleic acid molecule that is free of retroviral particles. The nucleic acid molecule comprises a nucleotide sequence that encodes a protein that comprises at least one epitope that is identical or substantially similar to an epitope of a pathogen antigen or an antigen associated with a hyperproliferative or autoimmune disease, a protein otherwise missing from the individual due to a missing, non-functional or partially functioning gene, or a protein that produces a therapeutic effect on an individual. Methods of prophylactically and therapeutically immunizing an individual against HIV are disclosed. Pharmaceutical compositions and kits for practicing methods of the present invention are disclosed.

Abstract translation: PCT No.PCT / US94 / 00899 Sec。 371日期：1995年8月28日 102（e）日期1995年8月28日PCT 1994年1月26日PCT PCT。 公开号WO94 / 16737 日期1994年8月4日公开了将遗传物质诱导入个体细胞的方法和用于实施其的组合物和试剂盒。 所述方法包括使个体的细胞与多核苷酸功能增强子接触并向细胞施用不含逆转录病毒颗粒的核酸分子的步骤。 核酸分子包含编码蛋白质的核苷酸序列，该蛋白质包含与病原体抗原或与过度增殖或自身免疫疾病相关的抗原的表位相同或基本相似的至少一个表位， 涉及缺失的，非功能的或部分功能的基因或对个体产生治疗作用的蛋白质。 公开了预防和治疗个体免受HIV感染的方法。 公开了用于本发明的实践方法的药物组合物和试剂盒。

公开(公告)号：US5322482A

公开(公告)日：1994-06-21

申请号：US52707

申请日：1993-04-27

Applicant: Wen-Bin Wang

Inventor： Wen-Bin Wang

IPC: B62M9/00 ,  F16G13/06 ,  F16G1/24

CPC classification number: B62M9/00 ,  F16G13/06

Abstract: Bicycle chain plate includes an inner plate having a pair of protruding portions at respective ends of on one side thereof adopted to be inserted into two holes of an outer plate, respectively. The outer plate has also a pair of prtoruding portions at respective ends of one side thereof adopted also to be inserted into two holes of the inner plate so that the inner and outer plates are securely fastened.

Abstract translation: 自行车链板包括内板，该内板在其一侧的相应端分别具有一对突出部分，以分别插入到外板的两个孔中。 外板还在其一侧的相应两端还具有插入内板的两个孔中的一对裁断部分，使得内外板牢固地固定。