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公开(公告)号:US10227648B2
公开(公告)日:2019-03-12
申请号:US15392557
申请日:2016-12-28
Applicant: 10X GENOMICS, INC.
Inventor: Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol
IPC: C12Q1/68 , C12Q1/6874 , C12Q1/6806 , C12Q1/683
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号:US10221442B2
公开(公告)日:2019-03-05
申请号:US14316447
申请日:2014-06-26
Applicant: 10X GENOMICS, INC.
Inventor: Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Serge Saxonov
IPC: C12Q1/68 , C12N15/10 , C12Q1/6806
Abstract: This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.
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公开(公告)号:US20180371540A1
公开(公告)日:2018-12-27
申请号:US16052486
申请日:2018-08-01
Applicant: 10X GENOMICS, INC.
Inventor: Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Donald Masquelier , Serge Saxonov , Landon Merrill , Andrew Price , Paul Hardenbol , Yuan Li
IPC: C12Q1/6874 , C12Q1/6806 , C12Q1/6869 , C12Q1/6855
Abstract: This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.
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公开(公告)号:US20180346979A1
公开(公告)日:2018-12-06
申请号:US16052431
申请日:2018-08-01
Applicant: 10X GENOMICS, INC.
Inventor: Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Serge Saxonov , Paul Hardenbol , Rajiv Bharadwaj , Xinying Zheng , Phillip Belgrader
IPC: C12Q1/6874 , C12Q1/6806 , C12Q1/6869 , C12Q1/6855
CPC classification number: C12Q1/6874 , C12Q1/6806 , C12Q1/6855 , C12Q1/6869
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号:US20180282804A1
公开(公告)日:2018-10-04
申请号:US16000803
申请日:2018-06-05
Applicant: 10X GENOMICS, INC.
Inventor: Benjamin Hindson , Serge Saxonov , Kevin Ness , Paul Hardenbol , Michael Schnall-Levin , Mirna Jarosz
IPC: C12Q1/6874 , C12Q1/6806 , C12Q1/6869 , C12Q1/6855
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号:US10030267B2
公开(公告)日:2018-07-24
申请号:US15832183
申请日:2017-12-05
Applicant: 10X GENOMICS, INC.
Inventor: Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Serge Saxonov
IPC: C12Q1/68 , C12Q1/6874 , C12Q1/6806 , C12Q1/683 , C12Q1/6804
CPC classification number: C12Q1/6874 , C12Q1/6804 , C12Q1/6806 , C12Q1/683 , C12Q2525/191 , C12Q2535/122 , C12Q2537/143 , C12Q2537/149 , C12Q2563/149 , C12Q2563/159 , C12Q2563/179 , C12Q2565/629
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号:US20180094314A1
公开(公告)日:2018-04-05
申请号:US15832183
申请日:2017-12-05
Applicant: 10X GENOMICS, INC.
Inventor: Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Serge Saxonov , Paul Hardenbol , Rajiv Bharadwaj , Xinying Zheng , Phillip Belgrader
IPC: C12Q1/68
CPC classification number: C12Q1/6874 , C12Q1/6804 , C12Q1/6806 , C12Q1/683 , C12Q2525/191 , C12Q2537/143 , C12Q2563/179 , C12Q2535/122 , C12Q2563/149 , C12Q2563/159 , C12Q2565/629
Abstract: The present disclosure provides compositions, methods, systems, and devices for polynucleotide processing. Such polynucleotide processing may be useful for a variety of applications, including polynucleotide sequencing.
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公开(公告)号:US20180051321A1
公开(公告)日:2018-02-22
申请号:US15718893
申请日:2017-09-28
Applicant: 10X Genomics, Inc.
Inventor: Benjamin Hindson , Christopher Hindson , Michael Schnall-Levin , Kevin Ness , Mirna Jarosz , Donald Masquelier , Serge Saxonov , Landon Merrill , Andrew Price , Paul Hardenbol , Yuan Li
CPC classification number: C12Q1/6806 , B01J2219/005 , B01J2219/00547 , B01J2219/00572 , B01J2219/00722 , C12N15/1006 , C12N15/1065 , C12Q2535/122 , C12Q2563/159
Abstract: This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.
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99.
公开(公告)号:US20180015472A1
公开(公告)日:2018-01-18
申请号:US15717840
申请日:2017-09-27
Applicant: 10X Genomics, Inc.
Inventor: Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
CPC classification number: B01L3/502761 , B01L3/0241 , B01L3/502784 , B01L2200/0673 , B01L2300/0816 , B01L2400/049 , B01L2400/086 , G01N35/085 , G01N2035/00237 , G01N2035/1034
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
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100.
公开(公告)号:US20170348691A1
公开(公告)日:2017-12-07
申请号:US15596754
申请日:2017-05-16
Applicant: 10X Genomics, Inc.
Inventor: Rajiv Bharadwaj , Kevin Ness , Debkishore Mitra , Donald Masquelier , Anthony Makarewicz , Christopher Hindson , Benjamin Hindson , Serge Saxonov
CPC classification number: B01L3/502761 , B01L3/0241 , B01L3/502784 , B01L2200/0673 , B01L2300/0816 , B01L2400/049 , B01L2400/086 , G01N35/085 , G01N2035/00237 , G01N2035/1034
Abstract: The disclosure provides devices, systems and methods for the generation of encapsulated reagents and the partitioning of encapsulated reagents for use in subsequent analyses and/or processing, such as in the field of biological analyses and characterization.
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