摘要:
The subject invention relates to isolated proteins, particularly monoclonal antibodies, which bind to the Nogo-66 receptor. Specifically, these antibodies have the ability to inhibit the binding of the natural ligand of the Nogo-66 receptor and neutralize the Nogo-66 receptor. These antibodies or portions thereof of the invention are useful for detecting NgR and for inhibiting NgR activity, for example in a human suffering from a disorder in which NgR or Nogo-66 activity is detrimental.
摘要:
The device comprises a device (2) for creating an essentially linear target (4) in an evacuated space where laser beams (1) are focused, the target being suitable for interacting with the focused laser beams (1) to emit a plasma emitting radiation in the extreme ultraviolet. A receiver device (3) receives the target (4) after it has interacted with the focused laser beams (1), and a collector device (110) collects the EUV radiation emitted by the target (4). The focusing elements (11) for focusing the laser beams on the target (4) are arranged in such a manner that the laser beams (1) are focused on the target (4) laterally, being situated in a common half-space relative to the target (4) and being inclined at a determined angle lying in the range about 60° to about 90° relative to a mean collection axis (6) perpendicular to the target (4). The collector device (110) is disposed symmetrically about the mean collection axis (6) in the half-space containing the laser beams (1) focused on the target (4) and inside a conical space (8) centered on the mean collection axis (6) with a vertex situated at the target (4) and a half-angle at the vertex that is less than the angle of inclination of the focused laser beams (1) relative to the mean collection axis (6). The device is suitable for use as a source for EUV radiation in lithography for fabricating integrated circuits.
摘要:
In order to realize a connector housing (10) that is tightly sealed relative to the environment, there is provided a device for an axially slidable connector-ended cable (5) because a contact holder (20) connected to the connector-ended cable can be displaced by a defined axial distance (C) within the connector housing, wherein a constant pressure is exerted upon the contact holder (35) of a corresponding female connector (3) by means of an integrated pressure spring (40).
摘要:
In at least one embodiment of the present invention a seat-belt retractor is provided. The seat-belt retractor comprises a locking system that is controlled by means of at least one vehicle-sensitive sensor. The sensor has an alignment mass for autonomous alignment and is configured to pivot on the seat-belt retractor when the angular installation position of the seat-belt retractor is changed and when the seat-belt is extended, the sensor can be fixed in position by a blocking device. The blocking device is friction-controlled by the rotation of the belt shaft in the extension direction. The blocking device includes a rotatably mounted blocking lever which can be displaced into a release position for the sensor by a control lever that is coupled to the belt shaft by a friction coupling when the belt shaft rotates in a retraction direction.
摘要:
A device for generating extreme ultraviolet (EUV) or soft X-ray radiation comprising: a laser source for producing a laser radiation which is focused to intensities beyond 106 W/cm2 onto a target to produce a plasma; and said electrodes located around the path of the plasma produced by the laser source; and said electrodes being combined with components for producing a rapid electric discharge in the plasma with a characteristic time constant which is less than the time constant of the laser produced plasma expansion time.
摘要翻译:一种用于产生极紫外(EUV)或软X射线辐射的装置,包括:用于产生激光辐射的激光源,其被聚焦到超过10 6 / W 2 / >到目标上以产生等离子体; 并且所述电极位于由激光源产生的等离子体的路径周围; 并且所述电极与用于在等离子体中产生快速放电的部件组合,其特征时间常数小于激光产生的等离子体膨胀时间的时间常数。
摘要:
A combination of belt retractor and belt pre-tensioner in which the pre-tensioning device is coupled to the belt shaft by means of the vehicle-sensitive or belt strap sensitive locking system of the belt retractor, is characterised in that a lever (16) entrained by the drive wheel (10) on its rotation in the pre-tensioning direction is mounted pivotally on the housing and on its pivoting movement effected by the rotation of the drive wheel (10) its free end (18) comes into engagement with the control disc (12) and in so doing, over part of its pivoting movement, drives the control disc (12) for its relative rotation relatively to the belt shaft and after the lever (16) has passed through its pivoting path serving to drive the control disc (12) it is released from the control disc (12) and the drive wheel (10).
摘要:
The invention relates to a method for positional optimisation in navigation, in particular neural navigation in surgery with an operation microscope and at least one optoelectronic image detector which may be connected to the microscope and also a computer system. The data obtained from the at least one image detector which lie in the microscope field-of-view for the operator, contain information on the position of an operation instrument, in particular the instrument tip. The actual position of the instrument in the x- and y-direction as well as in the z-direction of a three-dimensional coordinate system is continuously or intermittently determined from the relevant positional data. A separation determination is carried out for the positional determination in the z-direction by means of depth of focus evaluation and/or stereoscopic image analysis. The invention further relates to a navigation instrument, using marking, close to the instrument tip, lying within the field of view of the microscope during use thereof.
摘要:
In one embodiment the disclosure relates to an apparatus for depositing an organic material on a substrate, including a source heater for heating organic particles to form suspended organic particles; a transport stream for delivering the suspended organic particles to a discharge nozzle, the discharge nozzle having a plurality of micro-pores, the micro-pores providing a conduit for passage of the suspended organic particles; and a nozzle heater for pulsatingly heating the micro-pores nozzle to discharge the suspended organic particles from the discharge nozzle.
摘要:
An accelerometer (305) for measuring seismic data. The accelerometer (305) includes an integrated vent hole for use during a vacuum sealing process and a balanced metal pattern for reducing cap wafer bowing. The accelerometer (305) also includes a top cap press frame recess (405) and a bottom cap press frame recess (420) for isolating bonding pressures to specified regions of the accelerometer (305). The accelerometer (305) is vacuum-sealed and includes a balanced metal pattern (730) to prevent degradation of the performance of the accelerometer (305). A dicing process is performed on the accelerometer (305) to isolate the electrical leads of the accelerometer (305). The accelerometer (305) further includes overshock protection bumpers (720) and patterned metal electrodes to reduce stiction during the operation of the accelerometer (305).