公开(公告)号：US08660638B2

公开(公告)日：2014-02-25

申请号：US12616536

申请日：2009-11-11

申请人： Jeffrey E. Stahmann ,  John D. Hatlestad ,  Jesse W. Hartley ,  Avram Scheiner

发明人： Jeffrey E. Stahmann ,  John D. Hatlestad ,  Jesse W. Hartley ,  Avram Scheiner

IPC分类号： A61B5/0402

CPC分类号： A61B5/02028 ,  A61B5/0031 ,  A61B5/0205 ,  A61B5/0215 ,  A61B5/02405 ,  A61B5/0402 ,  A61B5/0476 ,  A61B5/11 ,  A61B5/1116 ,  A61B5/145 ,  A61B5/14532 ,  A61B5/14546 ,  A61N1/362 ,  A61N1/37247 ,  G06F19/00 ,  G06F19/3418 ,  G06F19/3481 ,  G16H40/63

摘要： Methods and systems are directed to acquiring and organizing information associated with at least one syncope event. A syncope event may be a suspected syncope event, a verified syncope event or a syncope event that is suspected and verified. Automated processes are used to collect information associated with at least one syncope event and organize the information as a syncope log entry. At least one of acquiring the information and organizing the information is performed at least in part implantably.

摘要翻译： 方法和系统旨在获取和组织与至少一个晕厥事件相关联的信息。 晕厥事件可能是疑似晕厥事件，经过验证的晕厥事件或怀疑和验证的晕厥事件。 自动进程用于收集与至少一个晕厥事件相关的信息，并将该信息组织为晕厥日志条目。 至少部分地可植入地执行获取信息和组织信息中的至少一个。

公开(公告)号：US08649862B2

公开(公告)日：2014-02-11

申请号：US13166297

申请日：2011-06-22

申请人： Jacob M. Ludwig ,  William J. Linder ,  Douglas J. Brandner ,  Nicholas J. Stessman ,  Douglas Michael Hannan ,  Scott R. Stubbs ,  Jeffrey E. Stahmann ,  Arthur Foster

发明人： Jacob M. Ludwig ,  William J. Linder ,  Douglas J. Brandner ,  Nicholas J. Stessman ,  Douglas Michael Hannan ,  Scott R. Stubbs ,  Jeffrey E. Stahmann ,  Arthur Foster

IPC分类号： A61N1/39

CPC分类号： A61N1/3931 ,  A61N1/025 ,  A61N1/3706 ,  A61N1/3937 ,  A61N1/3962 ,  A61N2001/083

摘要： A medical device can include a therapy circuit configured to provide a specified electrostimulation therapy to a tissue site, the specified electrostimulation therapy including a scheduled completion, the therapy circuit including a protection circuit configured to adjust specification of the electrostimulation therapy being provided so as to provide an adjusted electrostimulation therapy before the scheduled completion. The medical device can include a monitoring circuit comprising a comparator. The monitoring circuit can be configured to trigger the protection circuit to inhibit the therapy circuit when the therapy circuit output parameter exceeds the specified threshold as indicated by the comparator.

摘要翻译： 医疗设备可以包括治疗电路，其被配置为向组织部位提供特定的电刺激治疗，所述指定的电刺激治疗包括计划完成，所述治疗电路包括保护电路，该保护电路被配置为调整提供的电刺激治疗的规格， 在计划完成之前进行调整的电刺激治疗。 医疗装置可以包括包括比较器的监视电路。 当比较器所指示的治疗电路输出参数超过指定的阈值时，监视电路可被配置为触发保护电路来抑制治疗电路。

公开(公告)号：US08538522B2

公开(公告)日：2013-09-17

申请号：US13327428

申请日：2011-12-15

申请人： Jeffrey E. Stahmann ,  James O. Gilkerson ,  Krzysztof Z. Siejko ,  James Kalgren ,  Yinghong Yu

发明人： Jeffrey E. Stahmann ,  James O. Gilkerson ,  Krzysztof Z. Siejko ,  James Kalgren ,  Yinghong Yu

IPC分类号： A61N1/368 ,  A61N1/362 ,  A61N1/36

CPC分类号： A61N1/368

摘要： One way in which cardiac resynchronization therapy may be delivered is to only deliver paces to the left ventricle. If left ventricular pacing is inhibited during a cardiac cycle, it may be desirable to deliver a right ventricular safety pace to prevent asystole. Methods and devices for implementing right ventricular safety pacing in the context of multi-site left ventricular-only pacing are described.

摘要翻译： 进行心脏再同步治疗的一种方法是仅向左心室输送步伐。 如果在心动周期期间左心室起搏被抑制，则可能需要递送右心室安全步速以防止心搏停止。 描述了在多局部左心室起搏背景下实施右心室安全起搏的方法和装置。

公开(公告)号：US08523771B2

公开(公告)日：2013-09-03

申请号：US11674031

申请日：2007-02-12

申请人： Jeffrey E. Stahmann ,  Keith R. Maile

发明人： Jeffrey E. Stahmann ,  Keith R. Maile

IPC分类号： A61B5/02

CPC分类号： A61B5/0215 ,  A61B5/0031 ,  A61B5/0205 ,  A61B5/02055 ,  A61B5/02108 ,  A61B5/08 ,  A61B5/145 ,  A61B5/14546 ,  A61N1/36564 ,  A61N1/3702 ,  A61N1/37247

摘要： A system comprises an external medical device configured to communicate with a first implantable medical device (IMD). The external medical device includes a communication circuit and a display. The communication circuit is configured to receive information associated with cardiovascular pressure from the IMD. The external medical device is configured to annotate a waveform on the display to indicate one or more events associated with cardiovascular pressure.

摘要翻译： 一种系统包括被配置为与第一可植入医疗装置（IMD）通信的外部医疗装置。 外部医疗装置包括通信电路和显示器。 通信电路被配置为从IMD接收与心血管压力相关的信息。 外部医疗设备被配置为在显示器上注释波形以指示与心血管压力相关联的一个或多个事件。

公开(公告)号：US08483826B2

公开(公告)日：2013-07-09

申请号：US12405990

申请日：2009-03-17

申请人： John R. Zielinski ,  Shantha Arcot-Krishnamurthy ,  Joseph M. Pastore ,  Jeffrey E. Stahmann ,  Allan C. Shuros

发明人： John R. Zielinski ,  Shantha Arcot-Krishnamurthy ,  Joseph M. Pastore ,  Jeffrey E. Stahmann ,  Allan C. Shuros

IPC分类号： A61N1/00

CPC分类号： A61N1/3627 ,  A61N1/368 ,  A61N1/3688 ,  A61N1/3962

摘要： This document discusses, among other things, an apparatus comprising an implantable cardiac depolarization sensing circuit, an electrical stimulation circuit, and a pacing mode controller. The pacing mode controller is configured to deliver pacing therapy according to a first pacing mode that is a normal operating mode, and to deliver pacing therapy according to second and third pacing modes. The second and third pacing modes increase mechanical stress on at least a particular portion of the ventricle as compared to the pacing therapy delivered during the first pacing mode. The pacing mode controller alternates between the second and third pacing modes when pacing is changed from the normal operating mode to a stress augmentation mode. The pacing mode controller suspends the change from the normal operating mode to the stress augmentation mode when a condition to prevent the change is detected.

摘要翻译： 本文件尤其涉及包括可植入心脏去极化感测电路，电刺激电路和起搏模式控制器的装置。 起搏模式控制器被配置为根据作为正常操作模式的第一起搏模式提供起搏治疗，并且根据第二和第三起搏模式输送起搏治疗。 与在第一起搏模式期间递送的起搏治疗相比，第二和第三起搏模式增加至少在心室的特定部分上的机械应力。 当起搏从正常操作模式改变为应力增强模式时，起搏模式控制器在第二和第三起搏模式之间交替。 当检测到防止变化的条件时，起搏模式控制器将更改从正常操作模式暂停到应力增强模式。

公开(公告)号：US08475388B2

公开(公告)日：2013-07-02

申请号：US12847711

申请日：2010-07-30

申请人： Quan Ni ,  John D. Hatlestad ,  Jesse W. Hartley ,  Jeffrey E. Stahmann ,  Jaeho Kim ,  Kent Lee

发明人： Quan Ni ,  John D. Hatlestad ,  Jesse W. Hartley ,  Jeffrey E. Stahmann ,  Jaeho Kim ,  Kent Lee

IPC分类号： A61B5/08

CPC分类号： A61B5/4818 ,  A61B5/0205 ,  A61B5/4806 ,  A61B5/4809 ,  A61B5/7264

摘要： Devices and methods for detecting disordered breathing involve determining that the patient is asleep and sensing one or more signals associated with disordered breathing indicative of sleep-disordered breathing while the patient is asleep. Sleep-disordered breathing is detected using the sensed signals associated with disordered breathing. The sensed signals associated with disordered breathing may also be used to acquire a respiration pattern of one or more respiration cycles. Characteristics of the respiration pattern are determined. The respiration pattern is classified as a disordered breathing episode based on the characteristics of the respiration pattern. One or more processes involved in the detection of disordered breathing are performed using an implantable device.

摘要翻译： 用于检测无序呼吸的装置和方法涉及确定患者睡着并且感测与患者睡着时指示睡眠呼吸紊乱的无序呼吸相关联的一个或多个信号。 使用与无序呼吸相关的感测信号来检测睡眠呼吸障碍。 与无序呼吸相关联的感测信号也可用于获取一个或多个呼吸循环的呼吸模式。 确定呼吸模式的特征。 根据呼吸模式的特点，呼吸模式被分类为无序呼吸发作。 使用可植入装置进行涉及无序呼吸检测的一个或多个过程。

公开(公告)号：US08380296B2

公开(公告)日：2013-02-19

申请号：US12649753

申请日：2009-12-30

申请人： Kent Lee ,  Jeffrey E. Stahmann ,  Jesse W. Hartley ,  Quan Ni

发明人： Kent Lee ,  Jeffrey E. Stahmann ,  Jesse W. Hartley ,  Quan Ni

IPC分类号： A61B5/04

CPC分类号： A61N1/3601 ,  A61B5/04012 ,  A61B5/1107 ,  A61B5/4094 ,  A61B5/4818 ,  A61B5/6869 ,  A61B2505/09 ,  A61M16/024 ,  A61M16/10 ,  A61M2016/0039 ,  A61M2016/0042 ,  A61M2205/3561 ,  A61M2205/3584 ,  A61M2230/04 ,  A61M2230/10 ,  A61M2230/63 ,  A61N1/3611 ,  A61N1/36114 ,  A61N1/36135 ,  A61N1/36514

摘要： Systems and methods involve automatic activation, de-activation or modification of therapies or other medical processes based on brain state. A medical system includes a sensor system having one or more sensors configured to sense signals related to the brain state of the patient. A brain state analyzer detects various brain states, including sleep stage and/or brain seizures. A controller uses the brain state detection information to control a medical system configured to perform at least one respiratory or cardiac process. Methods involve sensing signals related to brain state and determining the brain state of a patient based on the sensed signals. At least one respiratory or cardiac medical process is controlled based on the patient's brain state.

摘要翻译： 系统和方法涉及基于脑状态的治疗或其他医疗过程的自动激活，去激活或修饰。 医疗系统包括具有一个或多个传感器的传感器系统，该传感器被配置为感测与患者的脑状态相关的信号。 脑状态分析仪检测各种脑状态，包括睡眠阶段和/或脑癫痫发作。 控制器使用脑状态检测信息来控制被配置为执行至少一个呼吸或心脏过程的医疗系统。 方法涉及感测与脑状态相关的信号，并且基于感测到的信号来确定患者的大脑状态。 至少一个呼吸或心脏医疗过程是根据患者的大脑状态进行控制的。

公开(公告)号：US08306630B2

公开(公告)日：2012-11-06

申请号：US12905336

申请日：2010-10-15

申请人： Scott R. Stubbs ,  Jeffrey E. Stahmann ,  Arthur J. Foster ,  Ronald W. Kunkel

发明人： Scott R. Stubbs ,  Jeffrey E. Stahmann ,  Arthur J. Foster ,  Ronald W. Kunkel

IPC分类号： A61N1/05

CPC分类号： A61N1/056 ,  A61N1/086

摘要： A medical device lead includes an insulative lead body, outer and inner conductive coils, and a flexible core assembly. The outer conductive coil extends through the lead body and is coupled to a first electrode at a distal end of the outer conductive coil. The inner conductive coil extends coaxially with the outer conductive coil, is coupled to a second electrode at a distal end of the inner conductive coil, and includes a central lumen. The flexible core assembly is disposed in the central lumen and is comprised of a material that has a saturation magnetization of at least about 1.5 T and a relative permeability of greater than one. The flexible core assembly includes a positioning interface configured for manipulation of the flexible core assembly such that the flexible core assembly translates through the central lumen during insertion and extraction of the flexible core assembly.

摘要翻译： 医疗器械引线包括绝缘引线体，外部和内部导电线圈以及柔性芯组件。 外部导电线圈延伸穿过引线体并且在外部导电线圈的远端处耦合到第一电极。 与外部导电线圈同轴地延伸的内部导电线圈耦合到内部导电线圈的远端处的第二电极，并且包括中心腔。 柔性芯组件设置在中心腔中，并且由具有至少约1.5T的饱和磁化强度和大于1的相对磁导率的材料构成。 柔性芯组件包括配置用于操纵柔性芯组件的定位接口，使得柔性芯组件在插入和拔出柔性芯组件期间通过中心腔平移。

公开(公告)号：US20120277601A1

公开(公告)日：2012-11-01

申请号：US13546872

申请日：2012-07-11

申请人： Jeffrey E. Stahmann

发明人： Jeffrey E. Stahmann

IPC分类号： A61B5/0215

CPC分类号： A61B5/02158 ,  A61B5/0031 ,  A61B5/0205 ,  A61N1/36557 ,  A61N1/36564

摘要： An implantable medical device receives a physiological signal indicative of circulatory blood volume and detects hypovolemia from that physiological signal. In one embodiment, an implantable pulmonary artery pressure (PAP) senses a PAP signal, and the implantable medical device detects hypovolemia from the PAP signal.

摘要翻译： 可植入医疗装置接收指示循环血容量的生理信号，并从该生理信号检测血容量不足。 在一个实施例中，可植入的肺动脉压（PAP）感测PAP信号，并且可植入医疗装置从PAP信号检测血容量不足。

公开(公告)号：US08251061B2

公开(公告)日：2012-08-28

申请号：US10929306

申请日：2004-08-30

申请人： Kent Lee ,  Jesse W. Hartley ,  Jeffrey E. Stahmann ,  Quan Ni

发明人： Kent Lee ,  Jesse W. Hartley ,  Jeffrey E. Stahmann ,  Quan Ni

IPC分类号： A61M15/00 ,  A61M16/00 ,  A61M15/08 ,  A62B7/00 ,  A62B9/02

CPC分类号： A61M16/024 ,  A61M2016/0039 ,  A61M2230/04 ,  A61M2230/08 ,  A61M2230/205 ,  A61M2230/63

摘要： A gas therapy system involves sensing the blood gas concentration of the patient and adapting a gas therapy based on the sensed gas concentration. Disordered breathing may be detected bases on blood gas concentration, and gas or cardiac electrical therapy may be adapted to treat the detected disordered breathing. One or more of sensing the blood gas concentration, detecting disordered breathing, or adapting the therapy may be performed at least in part implantably. The gas therapy is delivered to the patient through an external respiratory device, such as a positive airway pressure device.

摘要翻译： 气体治疗系统包括感测患者的血液气体浓度，并根据检测到的气体浓度调整气体治疗。 可能会根据血气浓度检测到无效呼吸，气体或心脏电疗可适用于治疗检测到的无序呼吸。 感测血气浓度，检测无序呼吸或适应治疗的一种或多种可以至少部分地可植入地进行。 气体治疗通过外部呼吸装置（例如气道正压装置）输送给患者。