Antibody recognizing C-domain of midkine
    91.
    发明授权
    Antibody recognizing C-domain of midkine 有权
    抗体识别中期因子的C结构域

    公开(公告)号:US09163081B2

    公开(公告)日:2015-10-20

    申请号:US12312522

    申请日:2007-11-13

    摘要: It is intended to provide an antibody which inhibits the function of midkine. An antibody which recognizes an epitope consisting of amino acid residues 62 to 104 of midkine or a fragment thereof; DNA encoding the antibody or a fragment thereof; a recombinant vector which contains the DNA; a transformant which has the vector or a hybridoma which produces the antibody; a method for producing the antibody by allowing the transformant or hybridoma to produce the antibody or a fragment thereof and collecting the resulting antibody or fragment thereof; a pharmaceutical composition containing the antibody or a fragment thereof as an active ingredient; and a diagnostic agent containing the antibody or a fragment thereof as an active ingredient.

    摘要翻译: 旨在提供抑制中期因子功能的抗体。 识别由中期因子的氨基酸残基62至104或其片段组成的表位的抗体; 编码抗体或其片段的DNA; 含有DNA的重组载体; 具有产生抗体的载体或杂交瘤的转化体; 通过使转化体或杂交瘤产生抗体或其片段并收集得到的抗体或其片段,制备抗体的方法; 含有抗体或其片段作为活性成分的药物组合物; 和含有该抗体或其片段作为活性成分的诊断剂。

    Communication system and communication apparatus
    92.
    发明授权
    Communication system and communication apparatus 有权
    通信系统和通信设备

    公开(公告)号:US09083477B2

    公开(公告)日:2015-07-14

    申请号:US13419710

    申请日:2012-03-14

    IPC分类号: H04B1/38 H04L12/40 H04J3/06

    摘要: A data storage processor of an HV-ECU transmits frame data including ID information indicating a kind of data and data information indicating the contents of the data to a motor ECU. When the motor ECU receives the frame data from the HV-ECU, a calculation processor of the motor ECU determines that the data information of the received frame data is data regarding the kind of data indicated by the ID information of the received frame data and executes a predetermined calculating process based on the data information. When the ID information of the frame data received from the HV-ECU is a synchronization ID, a data storage processor of the motor ECU starts a process of transmitting, to the HV-ECU, the frame data to be transmitted within the communication period.

    摘要翻译: HV-ECU的数据存储处理器向电动机ECU发送包括表示数据种类的ID信息的帧数据和表示数据内容的数据信息。 当电动机ECU从HV-ECU接收帧数据时,电动机ECU的计算处理器确定接收到的帧数据的数据信息是关于由接收到的帧数据的ID信息指示的数据种类的数据,并执行 基于数据信息的预定计算处理。 当从HV-ECU接收到的帧数据的ID信息是同步ID时,电动机ECU的数据存储处理器开始向HV-ECU发送在通信期间内要发送的帧数据的处理。

    Toner
    94.
    发明授权
    Toner 有权
    爽肤水

    公开(公告)号:US08614044B2

    公开(公告)日:2013-12-24

    申请号:US13159172

    申请日:2011-06-13

    IPC分类号: G03G9/00

    摘要: To provide a toner which can achieve both low-temperature fixing performance and dot reproducibility and further can obtain images on which any density non-uniformity has been kept from coming about, the toner has toner particles, each of the toner particles has a toner base particle containing a binder resin, a colorant and a release agent, and an inorganic fine powder; the toner having: (1) an average circularity of 0.960 or more; (2) a number-average molecular weight Mn(25° C.) of from 500 or more to 3,000 or less in measuring a tetrahydrofuran-soluble matter at 25° C. of the toner by SEC-MALLS; and (3) a value of Mn(135° C.)/Mn(25° C.) of from 25 or more to 50 or less which is the ratio of number-average molecular weight Mn(135° C.) in measuring an o-dichlorobenzene-soluble matter at 135° C. of the toner by SEC-MALLS to number-average molecular weight Mn(25° C.) in measuring a tetrahydrofuran-soluble matter at 25° C. of the toner by SEC-MALLS.

    摘要翻译: 为了提供能够实现低温定影性能和点再现性的调色剂,并且还可以获得不会发生任何密度不均匀的图像,调色剂具有调色剂颗粒,每个调色剂颗粒都具有调色剂基底 含有粘合剂树脂的颗粒,着色剂和脱模剂,以及无机细粉末; 调色剂具有:(1)平均圆形度为0.960以上; (2)通过SEC-MALLS测定调色剂的25℃下的四氢呋喃可溶物质中的数均分子量Mn(25℃)为500以上至3000以下; 和(3)在测量中数均分子量Mn(135℃)的比例为25以上至50以下的Mn(135℃)/ Mn(25℃)的值 通过SEC-MALLS将调色剂在135℃下的邻二氯苯可溶物质通过SEC-MALLS调节至数均分子量Mn(25℃),测定调色剂在25℃下的四氢呋喃可溶物质, 马尔斯

    Wiring board and liquid crystal display device
    95.
    发明授权
    Wiring board and liquid crystal display device 有权
    接线板和液晶显示装置

    公开(公告)号:US08310645B2

    公开(公告)日:2012-11-13

    申请号:US12995578

    申请日:2009-04-10

    IPC分类号: G02F1/1343 G02F1/1345

    摘要: A wiring board of the present invention has pads disposed in a plurality of rows including: first row pads each being connected to a respective one of the connection wires that is long in length; and second row pads (30b) each being connected to a respective one of the connection wires that is shorter in length than that of first connection wires (10a) connected to the first row pads, each of the first connection wires (10a) being provided not in a region between adjacent ones of the second row pads (30b) but in a lower layer region of the second row pads (30b), in such a manner that at least a first insulating layer (20a) is sandwiched between the second row pads (30b) and the first connection wires (10a), and 0.8≦W1/W2≦1, where W1 is a line width of the first connection wires (10a) in the lower layer region of the second row pads (30b), and W2 is a width of the second row pads (30b).

    摘要翻译: 本发明的布线基板具有排列成多行的焊盘,包括:第一行焊盘,各自连接到长度相等的连接线; 和第二排焊盘(30b)分别连接到长度比连接到第一行焊盘的第一连接线(10a)短的连接线中的每个连接线,每个第一连接线(10a)被设置 不是在相邻的第二列焊盘(30b)之间的区域中,而是在第二行焊盘(30b)的下层区域中,使得至少第一绝缘层(20a)夹在第二行 焊盘(30b)和第一连接线(10a),以及0.8< W1; W1 / W2≦̸ 1,其中W1是第二行焊盘(30b)的下层区域中的第一连接线(10a)的线宽, ,W2是第二排焊盘(30b)的宽度。

    WIRING BOARD AND LIQUID CRYSTAL DISPLAY DEVICE
    96.
    发明申请
    WIRING BOARD AND LIQUID CRYSTAL DISPLAY DEVICE 审中-公开
    接线板和液晶显示器件

    公开(公告)号:US20120006584A1

    公开(公告)日:2012-01-12

    申请号:US12673440

    申请日:2008-07-17

    IPC分类号: H05K1/09 H05K1/16 H05K1/11

    摘要: A wiring board of the present invention (1) is arranged so that: pads (30) arranged in a plurality of rows include: first-row pads (30a) connected to first metal wires (10a) among metal wires (10); and second-row pads (30b) connected to second metal wires (10b) among the metal wires (10), the first metal wires (10a) being longer than the second metal wires (10b); and that each of the first connecting lines (10a) is formed so as to be separated from a corresponding one of the second-row pads (30b) by at least an insulating layer, and so as to extend not through a region between the corresponding second-row pad (30b) and a second-row pad (30b) adjacent to the corresponding second-row pad (30b), but through a region below the corresponding second-row pad (30b).

    摘要翻译: 本发明的布线基板(1)的布置方式为:排列成多行的焊盘(30)包括:与金属线(10)之间的第一金属线(10a)连接的第一排焊盘(30a) 和连接到金属线(10)中的第二金属线(10b)的第二排焊盘(30b),第一金属线(10a)比第二金属线(10b)长; 并且所述第一连接线(10a)中的每一个形成为与至少一个绝缘层与所述第二排焊盘(30b)中的相应一个焊盘相隔离,并且不延伸通过所述第二焊盘 第二排衬垫(30b)和与相应的第二排衬垫(30b)相邻的第二排衬垫(30b),但是通过相应的第二排衬垫(30b)下方的区域。

    Aptamer against midkine and use thereof
    97.
    发明授权
    Aptamer against midkine and use thereof 有权
    适应中期因子和使用它

    公开(公告)号:US08080649B2

    公开(公告)日:2011-12-20

    申请号:US12312519

    申请日:2007-11-14

    IPC分类号: C07H21/02 C07H21/04 C12N15/11

    摘要: Provided is a high-quality aptamer against midkine.An aptamer possessing an inhibitory activity against midkine; a complex comprising an aptamer possessing a binding activity or inhibitory activity against midkine and a functional substance (for example, affinity substances, substances for labeling, enzymes, drug delivery vehicles, drugs and the like); a pharmaceutical drug, cell migration inhibitor, diagnostic reagent, labeling agent and the like comprising an aptamer possessing a binding activity or inhibitory activity against midkine, or a complex comprising the aptamer and a functional substance; a cell migration inhibitor, a diagnostic reagent, a labeling agent and the like.

    摘要翻译: 提供了针对midkine的高品质适配体。 具有抑制中期因子活性的适体; 包含具有对midkine的结合活性或抑制活性的适体和功能性物质(例如亲和性物质,标记物质,酶,药物递送载体,药物等)的配合物的复合物。 包含对midkine具有结合活性或抑制活性的适体的药物,细胞迁移抑制剂,诊断试剂,标记试剂等,或包含适体和功能性物质的复合物; 细胞迁移抑制剂,诊断试剂,标记试剂等。

    Power management device, control system, and control method
    99.
    发明授权
    Power management device, control system, and control method 失效
    电源管理装置,控制系统和控制方法

    公开(公告)号:US07677215B2

    公开(公告)日:2010-03-16

    申请号:US11785225

    申请日:2007-04-16

    IPC分类号: F02N11/08

    摘要: A power management device comprises a start management control unit having a starter hold control function for actuating a starter motor and holding the actuation based on an operating signal from a button switch, a first terminating unit for terminating cranking hold when receiving a starter stop instruction signal sent from an engine control device when it is determined that an engine reached a complete explosion, a second terminating unit for terminating cranking hold when it is determined that the engine reached a complete explosion based on an engine revolution signal sent from the engine control device, and a forced terminating unit for forcefully terminating cranking hold when cranking hold cannot be terminated by those terminating units.

    摘要翻译: 电源管理装置包括起动管理控制单元,其具有起动器保持控制功能,用于启动起动电动机并且基于来自按钮开关的操作信号保持动作;第一终端单元,用于当接收到起动器停止指令信号时终止启动保持 当确定发动机达到完全爆炸时,从发动机控制装置发送的第二终端单元,用于当基于从发动机控制装置发送的发动机转速信号确定发动机达到完全爆炸时终止起动保持的第二终止单元, 并且当启动保持时强制终止起动保持的强制终端单元不能被那些终端单元终止。

    APTAMER AGAINST MIDKINE AND USE THEREOF
    100.
    发明申请
    APTAMER AGAINST MIDKINE AND USE THEREOF 有权
    APTAMER反对MIDKINE及其使用

    公开(公告)号:US20100004432A1

    公开(公告)日:2010-01-07

    申请号:US12312519

    申请日:2007-11-14

    IPC分类号: C12N15/12

    摘要: Provided is a high-quality aptamer against midkine.An aptamer possessing an inhibitory activity against midkine; a complex comprising an aptamer possessing a binding activity or inhibitory activity against midkine and a functional substance (for example, affinity substances, substances for labeling, enzymes, drug delivery vehicles, drugs and the like); a pharmaceutical drug, cell migration inhibitor, diagnostic reagent, labeling agent and the like comprising an aptamer possessing a binding activity or inhibitory activity against midkine, or a complex comprising the aptamer and a functional substance; a cell migration inhibitor, a diagnostic reagent, a labeling agent and the like.

    摘要翻译: 提供了针对midkine的高品质适配体。 具有抑制中期因子活性的适体; 包含具有对midkine的结合活性或抑制活性的适体和功能性物质(例如亲和性物质,标记物质,酶,药物递送载体,药物等)的配合物的复合物。 包含对midkine具有结合活性或抑制活性的适体的药物,细胞迁移抑制剂,诊断试剂,标记试剂等,或包含适体和功能性物质的复合物; 细胞迁移抑制剂,诊断试剂,标记试剂等。