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    Methods for bypassing total or near-total obstructions in arteries or other anatomical conduits
    94.
    发明授权
    Methods for bypassing total or near-total obstructions in arteries or other anatomical conduits 有权
    绕过动脉或其他解剖导管中的全部或接近完全的障碍物的方法

    公开(公告)号：US06709444B1

    公开(公告)日：2004-03-23

    申请号：US09860147

    申请日：2001-05-17

    申请人： Joshua Makower

    发明人： Joshua Makower

    IPC分类号： A61M2500

    CPC分类号： A61M25/008 ,  A61B2017/00252 ,  A61B2017/22044 ,  A61B2017/22077 ,  A61B2017/22095 ,  A61F2/95 ,  A61M25/0053 ,  A61M25/0082 ,  A61M25/0084 ,  A61M2025/0081 ,  A61M2025/0092 ,  A61M2025/0197

    摘要： Methods for bypassing total or near-total obstructions in arteries or other anatomical conduits. A guidewire is advanced through the lumen of the artery or anatomical conduit upstream of the obstruction and past the obstruction. In navigating past the obstruction, this guidewire may advance through tissue that is located within the wall of the artery or anatomical conduit and/or through tissue that is located outside of the wall of the artery or anatomical conduit. After this guidewire has been advanced past the obstruction, a penetrating catheter that is equipped with an orientation element is advanced over that guidewire. The orientation element is then used to aim a penetrator back into the lumen of the obstructed artery or conduit, downstream of the obstruction. The penetrator is then advanced into the lumen of the obstructed artery or conduit, downstream of the obstruction, and a final guidewire is advanced through the penetrator and into the lumen of the artery or conduit downstream of the obstruction. The catheter (and the guidewire that was initially used to pass the obstruction) may then be removed, leaving the final guidewire in place. A balloon or other tract enlarging device may be used to dilate or otherwise enlarge the bypass tract through which the final guidewire extends. Also, a covered or uncovered stent may be placed within the tract to facilitate flow from the lumen of the artery or anatomical conduit upstream of the obstruction, through the newly created bypass tract and back into the lumen of the artery or anatomical conduit downstream of the obstruction.

    摘要翻译： 绕过动脉或其他解剖导管中的全部或接近完全的障碍物的方法。 导丝通过阻塞物上游的动脉或解剖导管的内腔前进通过障碍物。 在导航通过障碍物时，该导丝可以通过位于动脉或解剖导管的壁内的组织和/或通过位于动脉或解剖导管的壁外部的组织前进。 在该导丝已经超过障碍物之后，配备有取向元件的穿透导管在该导丝上前进。 然后使用定向元件将穿透器对准阻塞物下游的阻塞动脉或导管的内腔。 然后将穿透器推进到阻塞动脉或导管的内腔中，阻塞下游，并且最终导丝通过穿透器前进并进入阻塞下游的动脉或导管的内腔。 然后可以移除导管（以及最初用于通过障碍物的导丝），留下最终的导丝。 可以使用球囊或其它扩张装置来扩张或以其他方式扩大最终导丝通过其延伸的旁路管。 此外，覆盖或未覆盖的支架可以放置在管道内，以便于从阻塞物上游的动脉或解剖导管的内腔通过新产生的旁路管并且返回到动脉或解剖导管下游的解剖导管 梗阻。

    Method of making a hemostatic plug
    100.
    发明授权
    Method of making a hemostatic plug 失效
    制作止血栓的方法

    公开(公告)号：US5449375A

    公开(公告)日：1995-09-12

    申请号：US233450

    申请日：1994-04-26

    申请人： Claude A. Vidal ,  Russel J. Redmond ,  Joshua Makower

    发明人： Claude A. Vidal ,  Russel J. Redmond ,  Joshua Makower

    IPC分类号： A61B17/12 ,  A61B17/00 ,  A61B17/03 ,  A61L15/64

    CPC分类号： A61B17/0057 ,  A61B2017/00654

    摘要： A method of making a hemostatic plug for placement at a site where hemostatic treatment is indicated. The method comprises rolling a sheet of a hemostatic material a plurality of turns onto a generally cylindrical forming tool to thereby produce a rolled hemostatic plug having an opening therethrough along its longitudinal axis. In addition to employing one sheet of hemostatic material having a single density to form a plug, two sheets of hemostatic material having different densities can be rolled in tandem to each other on the forming tool, with one sheet overlapping an exposed wedge portion of the other sheet. The plugs thus formed can be longitudinally compressed if subsequent longitudinal expansion is desired. A typical placement site for which the plug is preferably employed is a puncture wound wherein an entry penetration of an artery and a tissue channel leading thereto are present.

    摘要翻译： 一种制备止血塞的方法，用于放置在指示止血治疗的部位。 该方法包括将止血材料的片材滚动到大致圆柱形的成形工具上，从而产生具有沿其纵向轴线穿过的开口的滚动止血塞。 除了使用一片具有单一密度的止血材料以形成塞子之外，具有不同密度的两片止血材料可以在成形工具上彼此串联地滚动，其中一片与另一层的暴露的楔形部分重叠 片。 如果需要随后的纵向膨胀，则如此形成的塞子可以被纵向压缩。 优选使用塞子的典型放置位置是穿刺伤口，其中存在通向其的动脉和组织通道的进入穿透。