NANOPOROUS GOLD NANOPARTICLES AS HIGH-PAYLOAD MOLECULAR CARGOS, PHOTOTHERMAL/PHOTODYNAMIC THERAPEUTIC AGENTS, AND ULTRAHIGH SURFACE-TO-VOLUME PLASMONIC SENSORS
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    发明申请
    NANOPOROUS GOLD NANOPARTICLES AS HIGH-PAYLOAD MOLECULAR CARGOS, PHOTOTHERMAL/PHOTODYNAMIC THERAPEUTIC AGENTS, AND ULTRAHIGH SURFACE-TO-VOLUME PLASMONIC SENSORS 有权
    纳米金纳米粒子作为高载体分子载体,光热/光化学治疗剂和超声波表面等离子体传感器

    公开(公告)号:US20140104606A1

    公开(公告)日:2014-04-17

    申请号:US13796201

    申请日:2013-03-12

    申请人: Wei-Chuan Shih

    发明人: Wei-Chuan Shih

    IPC分类号: G01N21/65 B22F9/16

    摘要: A nanoporous gold disk (NPGD) as a novel surface-enhanced Raman spectroscopy (SERS) substrate. NPGD has SERS enhancement factor similar to that of gold nanoshells, but allows, for example, at least three times more benzenethiol molecules to be attached to its surface due to large surface-to-volume ratio. The high capacity enables the rapid detection of attomole-level benzenethiol molecules with relatively high detector temperatures. Additionally, a fabrication process to make NPGD with controlled size and highly reproducible SERS activities.

    摘要翻译: 作为新型表面增强拉曼光谱(SERS)底物的纳米多孔金盘(NPGD)。 NPGD具有与金纳米壳相似的SERS增强因子,但由于表面体积比大,允许例如至少三次苯硫醇分子附着于其表面。 高容量能够以相对较高的检测器温度快速检测阿托莫尔级苯硫酚分子。 此外,制造过程使得NPGD具有受控的尺寸和高度可重现的SERS活动。