公开(公告)号：US20190126166A1

公开(公告)日：2019-05-02

申请号：US16306306

申请日：2017-05-05

申请人： IFP Energies nouvelles

发明人： Frederic AUGIER ,  Aude ROYON-LEBEAUD ,  Damien LEINEKUGEL LE COCQ ,  Alexandre VONNER

IPC分类号： B01D15/18 ,  B01D15/14 ,  B01D15/22 ,  C07C7/12 ,  C10G25/00

摘要： The present invention describes a device for distributing incoming fluid or for collecting fluid being discharged from a column forming part of an assembly of N columns in series intended to be used in a simulated moving bed separation process. The present device can be used to very substantially reduce the non-selective volumes at each column, while at the same time providing the flow with good synchronicity.

公开(公告)号：US20190079062A1

公开(公告)日：2019-03-14

申请号：US16125427

申请日：2018-09-07

申请人： Genentech, Inc.

发明人： Cadapakam VENKATRAMANI ,  Mohammad AL-SAYAH

IPC分类号： G01N30/46 ,  B01D15/32 ,  B01D15/40 ,  G01N30/88 ,  B01D15/18 ,  G01N30/74 ,  B01D15/38 ,  B01D15/14

摘要： Provided are two-dimensional chromatography systems and methods for separating and/or analyzing complex mixtures of organic compounds. In particularly, a two-dimensional reversed-phase liquid chromatography (RPLC)—supercritical fluid chromatography (SFC) system is described including a trapping column at the interface which collects the analytes eluted from the first dimension chromatography while letting the RPLC mobile phase pass through. The peaks of interest from the RPLC dimension column are effectively focused as sharp concentration pulses on the trapping column, which is subsequently injected onto the second dimension SFC column. The system can be used for simultaneous achiral and chiral analysis of pharmaceutical compounds. The first dimension RPLC separation provides the achiral purity result, and the second dimension SFC separation provides the chiral purity result (enantiomeric excess).

公开(公告)号：US20190038996A1

公开(公告)日：2019-02-07

申请号：US16154639

申请日：2018-10-08

申请人： GE Healthcare BioProcess R&D AB

发明人： KLAUS GEBAUER

IPC分类号： B01D15/14 ,  G01N30/46 ,  B01D15/18 ,  G01N30/60 ,  B01D15/22 ,  G01N30/88

摘要： A parallel assembly (2; 11; 51) of chromatography column modules (3a,b,c; 13a,b,c; 53a,b,c, 90a, b), the assembly having one common assembly inlet (15; 55) and one common assembly outlet (17; 57), each column module comprising a bed space (29) filled with chromatography medium and each column module comprises integrated fluid conduits which when the column module is connected with other column modules are adapted to connect the bed space (29) of the column module with the assembly inlet (15; 55) and the assembly outlet (17; 57), wherein the total length and/or volume of the fluid conduit from the assembly inlet to one bed space together with the length and/or volume of the fluid conduit from the same bed space to the assembly outlet is substantially the same for all bed spaces and modules installed in the parallel assembly.

公开(公告)号：US10183238B2

公开(公告)日：2019-01-22

申请号：US14383241

申请日：2013-03-05

申请人： Waters Technologies Corporation

发明人： Michael R. Jackson ,  James E. Usowicz ,  Lucas O. Tiziani ,  Joseph A. Jarrell ,  Douglas P. Wittmer

IPC分类号： B01D15/08 ,  B01D15/14 ,  B01D15/40 ,  F04B15/08 ,  G01N1/40 ,  G01N30/10 ,  G01N30/38 ,  G01N30/72 ,  G01N30/74 ,  G01N30/88 ,  H01J49/04 ,  G01N30/02 ,  F04B53/10 ,  G01N30/24

摘要： A method includes passing a mobile phase fluid flow comprising liquefied CO2 through a separation column; then introducing a makeup fluid flow into the mobile phase fluid flow to form a mixed fluid flow; and then splitting the mixed fluid flow.

公开(公告)号：US20190015762A1

公开(公告)日：2019-01-17

申请号：US16134319

申请日：2018-09-18

申请人： MTN Group, LLC

发明人： Mark S. Denton ,  Jeffrey T. Prince

IPC分类号： B01D15/22 ,  C02F1/42 ,  G21F9/12 ,  B01D15/36 ,  B01D15/18 ,  B01D15/14

CPC分类号： B01D15/22 ,  B01D15/14 ,  B01D15/1871 ,  B01D15/361 ,  C02F1/42 ,  C02F2101/006 ,  C02F2103/06 ,  C02F2103/10 ,  C02F2103/34 ,  C02F2301/08 ,  C02F2303/18 ,  G21F9/12

摘要： Surface or submersible sluiceable systems are disclosed for use in removing hazardous contaminants or radioactive isotopes from a fluid stream, such as a fluid stream from the primary coolant loop or secondary loop of a nuclear reactor system, or a fluid stream from a spent-fuel pool or pond or hazardous or radioactive contaminants in ground water. Generally, this surface or submersible sluiceable system is adapted to be utilized in a surface skid or submersed in the fluid stream, and additionally the vessels are adapted to be sluiced and reused after use, resulting in a potentially stabilized, non-leaching final waste product with a substantially reduced volume for storage or disposal. The system can be utilized with standard ion exchange beads or preferably with inorganic granular media.

公开(公告)号：US10052566B2

公开(公告)日：2018-08-21

申请号：US14759029

申请日：2014-12-02

申请人： MERCK PATENT GMBH

发明人： Guenter Hauke ,  Sebastien Marie ,  Leticia Garcia Diez ,  Michael Ukelis ,  Andreas Beirau ,  Michael Haeberl

IPC分类号： B01D15/22 ,  B01D15/14 ,  B01D15/08 ,  B01D15/20 ,  C09K19/34 ,  C09K19/54 ,  C09K19/04 ,  C09K19/30

CPC分类号： B01D15/22 ,  B01D15/08 ,  B01D15/14 ,  B01D15/206 ,  B01D2201/302 ,  B01D2201/304 ,  B01D2201/347 ,  C09K19/3003 ,  C09K19/3066 ,  C09K19/3402 ,  C09K19/542 ,  C09K2019/0448 ,  C09K2019/0466 ,  C09K2019/3004 ,  C09K2019/3009 ,  C09K2019/301 ,  C09K2019/3016 ,  C09K2019/3027 ,  C09K2019/3422 ,  C09K2019/548 ,  C09K2219/00

摘要： A purification device (1), for the purification of a liquid-crystal mixture, has a flow chamber (2) which has an inlet opening (3) and an outlet opening (4), arranged opposite the inlet opening, in order to be able to introduce the liquid-crystal mixture into the flow chamber (2) and discharge it from the latter, and at least one flow distribution element (5) which is arranged in the flow chamber (2) in the region of the inlet opening (3), and at least one filter element (6) which is arranged in the region of the outlet opening (4), where a length of the flow chamber (2) measured in the flow direction is at least a factor of 2 greater than a greatest internal dimension of the flow chamber (2) transverse to the flow direction.

公开(公告)号：US20180145349A1

公开(公告)日：2018-05-24

申请号：US15819240

申请日：2017-11-21

申请人： TOYODA GOSEI CO., LTD.

发明人： Naoki YAMAGUCHI ,  Kosuke KUSABA ,  Tatsuya OJIO

IPC分类号： H01M8/04044 ,  B01D15/36 ,  B01D15/14 ,  H01M8/04029

CPC分类号： H01M8/04044 ,  B01D15/14 ,  B01D15/362 ,  B01D15/363 ,  H01M8/04029 ,  H01M2008/1095 ,  H01M2250/20

摘要： An ion exchanger used in a cooling system of a fuel cell system, includes: a communicating tube portion including a first flow path which allows coolant introduced from one side to pass therethrough to the other side; a case portion which is provided to communicate with the communicating tube portion; and a storage body which is assembled to the case portion, has a second flow path in which a part of the coolant branches and flows from the communicating tube portion, and is merged with the communicating tube portion again, and stores an ion exchange resin in the second flow path, wherein: an assembled state of the storage body with respect to the case portion is changeable into a plurality of kinds; and a proportion of the coolant that flows to the second flow path is changeable by changing the assembled state of the storage body.

公开(公告)号：US20180117496A1

公开(公告)日：2018-05-03

申请号：US15788894

申请日：2017-10-20

申请人： TOYOTA BOSHOKU KABUSHIKI KAISHA

发明人： Junko OHIRA

IPC分类号： B01D15/36 ,  H01M8/04029 ,  H01M8/04007 ,  B01D15/14 ,  B01J47/12

CPC分类号： B01D15/361 ,  B01D15/14 ,  B01D15/1885 ,  B01J47/024 ,  B01J47/12 ,  H01M8/04029 ,  H01M8/04044 ,  H01M8/04074 ,  H01M2250/20

摘要： An ion exchanger includes a housing, which includes an inlet and an outlet for a coolant and is open upwardly, and a cartridge mounted within the housing so as to be removable upwardly out of the housing. The cartridge includes a first case and a second case respectively located above and below the inlet and the outlet and capable of containing an ion exchange resin. The first case includes a first flow entrance, which is in fluid communication with the inlet of the housing, and a first flow exit, which is in fluid communication with the outlet of the housing. The second case includes a second flow entrance in fluid communication with the inlet of the housing and a second flow exit in fluid communication with the outlet of the housing.

公开(公告)号：US20180100836A1

公开(公告)日：2018-04-12

申请号：US15834252

申请日：2017-12-07

申请人： ALPS ELECTRIC CO., LTD.

发明人： Yoshimune SUZUKI ,  Setsuo Ishibashi ,  Yoshihiro Taguchi ,  Satoshi Kawamura ,  Junko Ito ,  Minaguchi Hiroyoshi

IPC分类号： G01N30/32 ,  B01D15/14 ,  B01D15/18 ,  B01D15/22 ,  G01N30/60 ,  B01J20/281

CPC分类号： G01N30/32 ,  B01D15/14 ,  B01D15/1885 ,  B01D15/22 ,  G01N30/482 ,  G01N30/6047 ,  G01N2030/027

摘要： A flow passage unit has a column for used in a liquid chromatograph and a support body that supports the column. The column has: a porous stationary phase; a porous pressure adjusting part disposed at least at the flow-in end of the stationary phase, a liquid entering the flow-in end, the pressure adjusting part being harder than the stationary phase; and a covering part that covers the stationary phase and pressure adjusting part. The support body has a first plate and a second plate that are mutually joined, the support body forming a column holding part and a liquid flow passage, the column holding part holding the column between the first plate and the second plate, the liquid flow passage communicating with the column holding part. Pressure applied from the first plate and second plate to the pressure adjusting part is higher than pressure applied to the stationary phase.

公开(公告)号：US20170320901A1

公开(公告)日：2017-11-09

申请号：US15526139

申请日：2015-11-12

申请人： GE Healthcare Limited

发明人： Xavier Franci ,  Steve Lignon ,  Audrey Marie Lange ,  Nicolas Verbrugge

IPC分类号： C07H5/02 ,  B01D15/42 ,  B01J47/022 ,  B01J41/20 ,  A61K51/04 ,  B01J41/09 ,  B01D15/36 ,  B01D15/18 ,  B01D15/14 ,  C07H1/06 ,  B01J41/04

CPC分类号： C07H5/02 ,  A61K51/0497 ,  B01D15/14 ,  B01D15/1885 ,  B01D15/363 ,  B01D15/424 ,  B01J41/04 ,  B01J41/09 ,  B01J41/20 ,  B01J47/022 ,  C07B59/00 ,  C07B2200/05 ,  C07H1/06

摘要： The present invention provides a new chemical process, a new cassette configuration, and new software for the automated production of multiple batches of an [18F]labelled compound on a single cassette. The invention allows one synthesizer in one hot cell to produce sequentially a plurality of batches of [18F]-labelled PET tracer in the same day. In particular, the present invention provides a novel arrangement useful for the trapping of [18F]fluoride and recovery of [18O]water.