公开(公告)号：US20070128731A1

公开(公告)日：2007-06-07

申请号：US11634694

申请日：2006-12-06

申请人： Subodh Deshmukh ,  Mahmoud Mirmehrabi

发明人： Subodh Deshmukh ,  Mahmoud Mirmehrabi

IPC分类号： G01N25/20

CPC分类号： C07D498/18 ,  C07D498/14 ,  C07H17/08 ,  G01N25/4866

摘要： Methods for purifying rapamycin are described. Methods for measuring particle quality, median particle size, and crystallinity of samples containing rapamycin or a derivative thereof are also provided.

摘要翻译： 描述了雷帕霉素的纯化方法。 还提供了用于测量含有雷帕霉素或其衍生物的样品的颗粒质量，中值粒径和结晶度的方法。

公开(公告)号：US07188001B2

公开(公告)日：2007-03-06

申请号：US10353186

申请日：2003-01-27

申请人： Steven J. Young ,  Gregory T. A. Kovacs ,  M. Allen Northrup ,  Kurt E. Petersen ,  William A. McMillan ,  Konstantin Othmer ,  Lee A. Christel

发明人： Steven J. Young ,  Gregory T. A. Kovacs ,  M. Allen Northrup ,  Kurt E. Petersen ,  William A. McMillan ,  Konstantin Othmer ,  Lee A. Christel

IPC分类号： G05B21/00 ,  G01N25/20 ,  G01N21/00

CPC分类号： B01L7/52 ,  G05B13/021 ,  G05D23/1913 ,  Y10T436/12

摘要： A system for controlling the temperature of a reaction mixture comprises at least one heating device for heating the mixture and a power regulator for regulating the amount of power supplied to the heating device. A controller in communication with the power regulator includes program instructions for heating the reaction mixture by setting a variable target temperature that initially exceeds a desired setpoint temperature for the mixture. When the heating device reaches a threshold temperature, the variable target temperature is decreased to the desired setpoint temperature. In another embodiment, the controller includes an adaptive control program for dynamically adjusting the duration or intensity of power pulses provided to the heating device.

摘要翻译： 用于控制反应混合物的温度的系统包括至少一个用于加热混合物的加热装置和用于调节供应给加热装置的功率量的功率调节器。 与功率调节器通信的控制器包括用于通过设定最初超过混合物的期望设定点温度的可变目标温度来加热反应混合物的程序指令。 当加热装置达到阈值温度时，可变目标温度降低到所需的设定点温度。 在另一个实施例中，控制器包括用于动态调整提供给加热装置的功率脉冲的持续时间或强度的自适应控制程序。

公开(公告)号：US20060239328A1

公开(公告)日：2006-10-26

申请号：US11110701

申请日：2005-04-21

申请人： Chikayoshi Sumi

发明人： Chikayoshi Sumi

IPC分类号： G01N25/20

CPC分类号： G01N25/18

摘要： A thermal property measurement apparatus capable of directly measuring thermal conductivity distribution in a ROI within a target only by measuring the temperature distribution that already exists in the ROI without generating other temperature fields artificially. The thermal property measurement apparatus includes a temperature detector for measuring temperatures at plural positions in the ROI, a distance controller for controlling a distance between the temperature detector and the target, a scanner for changing a relative position therebetween, a stage for putting the object thereon, a recorder for recording measured temperature data, position data and time data, a determination unit for determining whether at least one of thermal conductive phenomena and convection phenomena is dealt with or not, a processor for calculating thermal conductivity distribution in the ROI from the recorded data and temporal changeable references of the thermal conductivity in the ROI, and a controller.

摘要翻译： 一种热能测量装置，其能够通过测量已经存在于ROI中的温度分布直接测量目标内的ROI中的导热率分布，而不产生人为的其他温度场。 热性能测量装置包括用于测量ROI中的多个位置的温度的温度检测器，用于控制温度检测器和目标之间的距离的距离控制器，用于改变其间的相对位置的扫描仪，用于将物体放置在其上的台 用于记录测量的温度数据，位置数据和时间数据的记录器，用于确定是否处理热传导现象和对流现象中的至少一个的确定单元，用于从记录的所述ROI计算所述ROI中的热导率分布的处理器 ROI中的热导率的数据和时间可变参考，以及控制器。

公开(公告)号：US07048434B2

公开(公告)日：2006-05-23

申请号：US10247048

申请日：2002-09-17

申请人： Alex Tregub ,  Mansour Moinpour ,  David Fryer

发明人： Alex Tregub ,  Mansour Moinpour ,  David Fryer

IPC分类号： G01N25/20

CPC分类号： G01N25/4846

摘要： Thermally analysis of layers and multiple layer structures used in the semiconductor processing arts is disclosed. A modulated calorimetric analysis may be used to determine a thermal signature that characterizes the chemical properties of a sample of material. The signature may include one or more thermal properties such as heat capacities. The signature may be used to compare and infer the suitability of a material for use in an integrated circuit manufacturing process. A thermal signature for a material that is not known to be suitable for manufacturing integrated circuits may be compared with a thermal signature for a standard material that is known to be suitable in order to determine whether the aforementioned material is suitable. Multiple layer structures may also be analyzed, compared, and inferred, and approaches for determining thermal signatures for any individual layer of the multiple layer structure are disclosed.

摘要翻译： 公开了半导体加工领域中使用的层和多层结构的热分析。 可以使用调制的量热分析来确定表征材料样品的化学性质的热特征。 签名可以包括一个或多个热性质，例如热容量。 签名可用于比较和推断用于集成电路制造过程中的材料的适用性。 可以将不知道适合于制造集成电路的材料的热学特征与已知适合于确定上述材料是否合适的标准材料的热学特征进行比较。 还可以分析，比较和推断多层结构，并且公开了用于确定多层结构的任何单独层的热特征的方法。

公开(公告)号：US20050287033A1

公开(公告)日：2005-12-29

申请号：US11019107

申请日：2004-12-22

申请人： Kevin Thurbide

发明人： Kevin Thurbide

IPC分类号： G01N21/72 ,  G01N25/20 ,  G01N30/68

CPC分类号： G01N21/72

摘要： A micro counter-current flame detector is provided that is both sensitive for photometric and ionization detection for gas chromatography (GC). In the detector, a stainless steel capillary (0.01″ i.d.) supplying oxygen functions as a burner, which supports a compact flame that burns in a counter-flowing excess of hydrogen. In the “micro Flame Photometric Detector” (μFPD) response mode, the background emission level is reduced by over an order of magnitude compared to previous experiments using a fused silica capillary burner, resulting in greatly improved detection limits. The device can successfully operate as both a selective and universal GC detector. Results indicate that this micro counter-current flame method yields comparable performance to conventional Flame Photometric and Flame Ionization Detectors.

摘要翻译： 提供了一种对气相色谱（GC）进行光度和电离检测敏感的微型逆流火焰探测器。 在检测器中，供应氧气的不锈钢毛细管（0.01“i.d.”）作为燃烧器起作用，其支持紧凑的火焰，其以反向流过的氢气燃烧。 在“微火焰光度检测器”（muFPD）响应模式中，与使用熔融石英毛细管燃烧器的先前实验相比，背景排放水平降低超过一个数量级，从而大大提高了检测限。 该装置可以成功地作为选择性和通用GC检测器进行操作。 结果表明，这种微型逆流火焰法与传统的火焰光度和火焰离子化检测器产生可比性能。

公开(公告)号：US06913383B2

公开(公告)日：2005-07-05

申请号：US10459112

申请日：2003-06-09

申请人： Urs Jörimann ,  Thomas Hütter

发明人： Urs Jörimann ,  Thomas Hütter

IPC分类号： G01N25/20 ,  G01N25/48 ,  G01K17/00 ,  G01N25/00

CPC分类号： G01N25/4833 ,  G01N25/4866

摘要： A method and apparatus for thermally investigating a material by driving the material through a temperature profile composed of isothermal and non-isothermal segments is disclosed, which enable determination of a kinetic component in a measured heat flow signal caused by the exposure of the material to the temperature profile.

摘要翻译： 公开了一种用于通过驱动材料通过由等温和非等温段组成的温度曲线来热研究材料的方法和装置，其能够确定由材料暴露于所述材料引起的测量的热流信号中的动力学分量 温度曲线。

公开(公告)号：US20050141587A1

公开(公告)日：2005-06-30

申请号：US10504359

申请日：2003-02-11

申请人： Peter Muhlig ,  Thomas Klupsch ,  Rolf Hilgenfeld ,  Hans-Jurgen Kiel ,  Axel Walter

发明人： Peter Muhlig ,  Thomas Klupsch ,  Rolf Hilgenfeld ,  Hans-Jurgen Kiel ,  Axel Walter

IPC分类号： G01K17/00 ,  G01N25/02 ,  G01N25/20 ,  G01N25/48 ,  G01N25/00 ,  G01J5/00

CPC分类号： G01N25/02 ,  G01K17/006 ,  G01N25/4846

摘要： The invention relates to a device for measuring quantities of heat while simultaneously measuring the evaporation kinetics and/or condensation kinetics of the most minute amounts of liquid in order to determine thermodynamic parameters. The aim of the invention is to determine low thermal outputs, which are absorbed or released by the sample, as well as small differences between thermal outputs with regard to a reference measurement of the same magnitude. To this end, a most minute amount of liquid is located inside a measuring chamber having a constant temperature and air humidity. At least one thermal sensor is provided for repeatedly measuring the thermal radiation emitted from the most minute amount of liquid. A measuring means serves to determine the time-dependent change in the most minute amount of liquid. A computer is assigned to the measuring chamber in order to register, display, evaluate and/or subsequently process the measured values.

摘要翻译： 本发明涉及一种用于测量热量的装置，同时测量最微量的液体的蒸发动力学和/或冷凝动力学，以便确定热力学参数。 本发明的目的是确定由样品吸收或释放的低热输出以及相对于相同量值的参考测量的热输出之间的小差异。 为此，最小量的液体位于具有恒定温度和空气湿度的测量室内。 提供至少一个热传感器用于重复测量从最微量的液体发射的热辐射。 测量装置用于确定最微量的液体的时间依赖性变化。 计算机被分配到测量室以便注册，显示，评估和/或随后处理测量值。

公开(公告)号：US06901349B2

公开(公告)日：2005-05-31

申请号：US10644717

申请日：2003-08-20

申请人： Jun Nagasawa

发明人： Jun Nagasawa

IPC分类号： G01N25/20 ,  G01N25/00 ,  G01V13/00 ,  G21C17/112 ,  G01N27/18 ,  G06F19/00

CPC分类号： G01V13/00

摘要： An analysis apparatus has a measurement head for measuring characteristics of a sample, a calibration conditions file comprising at least one calibration condition obtained by carrying out device calibration for the measurement head in advance, and a measurement head controller for designating one of the calibration conditions within the calibration conditions file. Measurement sequence data comprised of a sequence of measurement steps has measurement conditions for carrying out measurements by the measurement head and the calibration conditions designated by the measurement head controller. A measurement device refers to each measurement step of the measurement sequence data and carries out measurement after inputting the measurement conditions and the calibration conditions for each measurement step to the measurement head.

摘要翻译： 分析装置具有用于测量样本特性的测量头，包括通过预先对测量头进行设备校准获得的至少一个校准条件的校准条件文件，以及用于指定校准条件之一的测量头控制器 校准条件文件。 由测量步骤序列组成的测量序列数据具有用于通过测量头进行测量的测量条件和由测量头控制器指定的校准条件。 测量装置是指测量序列数据的每个测量步骤，并且在将测量条件和每个测量步骤的校准条件输入到测量头之后进行测量。

公开(公告)号：US06881584B1

公开(公告)日：2005-04-19

申请号：US09441493

申请日：1999-11-17

申请人： James Martin Lenhard ,  Mark Andrew Paulik

发明人： James Martin Lenhard ,  Mark Andrew Paulik

IPC分类号： A61B5/00 ,  A61B5/103 ,  G01N25/72 ,  G01N33/483 ,  G01N25/20

CPC分类号： A61B5/444 ,  A61B5/0059 ,  A61B5/015 ,  A61B5/415 ,  A61B5/416 ,  A61B5/445 ,  A61B5/7425 ,  A61B2503/40

摘要： The present invention relates, in general, to thermography and, in particular, to a method of using infrared thermography to monitor physiological and molecular events that elicit a thermogenic response in animals (including humans), plants, tissues, cells and cell-free systems. The present method can be used for screening, identifying, and ranking drug candidates for multiple diseases, disorders and conditions.

公开(公告)号：US06846455B1

公开(公告)日：2005-01-25

申请号：US09796738

申请日：2001-03-02

申请人： Christopher F. Carney ,  Fred L. Ferguson ,  John R. Reader ,  Weidong Liu ,  Jay A. Crosby

发明人： Christopher F. Carney ,  Fred L. Ferguson ,  John R. Reader ,  Weidong Liu ,  Jay A. Crosby

IPC分类号： B25J15/00 ,  B25J15/12 ,  G01N25/20 ,  G01N35/00 ,  G01N35/02 ,  G05B19/04

CPC分类号： B25J15/12 ,  G01N25/20 ,  G01N35/0099 ,  G01N35/025 ,  G01N2035/00207 ,  G01N2035/00356

摘要： The invention relates to an automatic sampler device. According to one aspect, the automatic sampler includes a cell having a sample platform and a reference platform; a sample tray; and a sample arm. The sample tray has wells into which sample pans and reference pans are inserted. The geometry of the automatic sampler device permits the sample platform, the reference platform, and the wells in the sample tray to be accessed by the sample arm along a common arc. According to another aspect, the automatic sampler device includes a sample tray with wells, a sample arm, and a gripper device. The gripper device has gripping fingers. The gripping fingers open or close in a manner that tends to center objects grasped by the gripper device. According to another aspect, the automatic sampler device includes a sample tray with wells, a sample arm, and a gripper device. The sample arm has an optical sensor and an electrical sensor. The optical sensor and electrical sensor can be used to detect a pan grasped by the gripper device. According to another aspect, the automatic sampler device includes a sample tray with wells, a sample arm, and a gripper device. The gripper advice is capable of grasping pans of different sizes.

摘要翻译： 本发明涉及一种自动取样装置。 根据一个方面，自动采样器包括具有采样平台和参考平台的单元; 样品托盘 和样品臂。 样品盘具有插入样品平底锅和参考平底锅的孔。 自动取样器装置的几何形状允许样品平台，参考平台和样品托盘中的孔沿着共同弧由样品臂进入。 根据另一方面，自动取样器装置包括具有孔的样品盘，样品臂和夹持装置。 夹持装置具有夹持指状物。 夹持指状物以使夹持装置夹持的物体趋于中心的方式打开或关闭。 根据另一方面，自动取样器装置包括具有孔的样品盘，样品臂和夹持装置。 样品臂具有光学传感器和电传感器。 光学传感器和电传感器可用于检测由夹具装置抓住的盘。 根据另一方面，自动取样器装置包括具有孔的样品盘，样品臂和夹持装置。 夹具建议能够抓住不同尺寸的平底锅。