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211 条记录 (耗时 0.042 秒)

    METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS
    101.
    发明申请
    METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS 审中-公开

    公开(公告)号：US20190336605A1

    公开(公告)日：2019-11-07

    申请号：US16514066

    申请日：2019-07-17

    申请人： Immunolight, LLC.

    发明人： Frederic A. BOURKE, JR.

    IPC分类号： A61K41/00 ,  A61K31/37 ,  A61F7/00 ,  A61K45/06 ,  A61K31/35 ,  A61K31/714 ,  A61N5/06 ,  A61H23/00 ,  A61K31/366 ,  A61N2/02 ,  A61K47/02 ,  A61N5/10

    摘要： Methods for the treatment of a cell proliferation disorder in a subject, involving: (1) administering to the subject at least one activatable pharmaceutical agent that is capable of effecting a predetermined cellular change when activated, either alone or in combination with at least one energy modulation agent; and (2) applying an initiation energy from an initiation energy source to the subject, wherein the applying activates the activatable agent in situ, thus causing the predetermined cellular change to occur, wherein the predetermined cellular change treats the cell proliferation disorder, preferably by causing an increase or decrease in rate of cell proliferation, and a kit for performing the method, a computer implemented system for performing the method, a pharmaceutical composition useful in the method and a method for causing an autovaccine effect in a subject using the method.

    ADHESIVE BONDING COMPOSITION AND ELECTRONIC COMPONENTS PREPARED FROM THE SAME
    105.
    发明申请
    ADHESIVE BONDING COMPOSITION AND ELECTRONIC COMPONENTS PREPARED FROM THE SAME 审中-公开

    公开(公告)号：US20190157234A1

    公开(公告)日：2019-05-23

    申请号：US16252060

    申请日：2019-01-18

    申请人： Immunolight, LLC.

    发明人： Zakaryae FATHI ,  James Clayton ,  Harold Walder ,  Frederic A. Bourke, JR.

    IPC分类号： H01L23/00 ,  C09J9/02 ,  C09J163/00 ,  C09J11/02

    摘要： A curable resin or adhesive composition includes at least one monomer, a photoinitiator capable of initiating polymerization of the monomer when exposed to light, and at least one energy converting material, preferably a phosphor, capable of producing light when exposed to radiation (typically X-rays). The material is particularly suitable for bonding components at ambient temperature in situations where the bond joint is not accessible to an external light source. An associated method includes: placing a polymerizable adhesive composition, including a photoinitiator and energy converting material, such as a down-converting phosphor, in contact with at least two components to be bonded to form an assembly; and, irradiating the assembly with radiation at a first wavelength, capable of conversion (down-conversion by the phosphor) to a second wavelength capable of activating the photoinitiator, to prepare items such as inkjet cartridges, wafer-to-wafer assemblies, semiconductors, integrated circuits, and the like.

    ADHESIVE BONDING COMPOSITION AND ELECTRONIC COMPONENTS PREPARED FROM THE SAME
    107.
    发明申请
    ADHESIVE BONDING COMPOSITION AND ELECTRONIC COMPONENTS PREPARED FROM THE SAME 审中-公开

    公开(公告)号：US20180269174A1

    公开(公告)日：2018-09-20

    申请号：US15459907

    申请日：2017-03-15

    申请人： Immunolight, LLC

    发明人： Zakaryae FATHI ,  James CLAYTON ,  Harold WALDER ,  Frederic A. BOURKE, JR.

    IPC分类号： H01L23/00 ,  C09J9/02 ,  C09J11/02 ,  C09J163/00

    CPC分类号： H01L24/29 ,  C09J9/02 ,  C09J11/02 ,  C09J163/00 ,  H01L2224/2929

    摘要： A curable resin or adhesive composition includes at least one monomer, a photoinitiator capable of initiating polymerization of the monomer when exposed to light, and at least one energy converting material, preferably a phosphor, capable of producing light when exposed to radiation (typically X-rays). The material is particularly suitable for bonding components at ambient temperature in situations where the bond joint is not accessible to an external light source. An associated method includes: placing a polymerizable adhesive composition, including a photoinitiator and energy converting material, such as a down-converting phosphor, in contact with at least two components to be bonded to form an assembly; and, irradiating the assembly with radiation at a first wavelength, capable of conversion (down-conversion by the phosphor) to a second wavelength capable of activating the photoinitiator, to prepare items such as inkjet cartridges, wafer-to-wafer assemblies, semiconductors, integrated circuits, and the like.

    Modulating a biological activity of a target structure by energy generation in-situ within a medium
    108.
    发明授权
    Modulating a biological activity of a target structure by energy generation in-situ within a medium 有权

    公开(公告)号：US09993661B2

    公开(公告)日：2018-06-12

    申请号：US15649956

    申请日：2017-07-14

    申请人： IMMUNOLIGHT, LLC.

    发明人： Frederic A. Bourke, Jr. ,  Harold Walder

    IPC分类号： A61N5/06 ,  A61N5/10 ,  A61K41/00

    CPC分类号： A61N5/062 ,  A61K41/0085 ,  A61N5/0622 ,  A61N5/1077 ,  A61N2005/0661 ,  A61N2005/1091 ,  A61N2005/1098

    摘要： A system and method for light stimulation within a medium. Products, compositions, systems, and methods for modifying a target structure which mediates or is associated with a biological activity, including treatment of conditions, disorders, or diseases mediated by or associated with a target structure, such as a virus, cell, subcellular structure or extracellular structure. The methods may be performed in situ in a non-invasive manner by application of an initiation energy to a subject thus producing an effect on or change to the target structure directly or via a modulation agent. The methods may further be performed by application of an initiation energy to a subject in situ to activate a pharmaceutical agent directly or via an energy modulation agent, thus producing an effect on or change to the target structure. Kits containing products or compositions formulated or configured and systems for use in practicing these methods.