公开(公告)号：US10123928B2

公开(公告)日：2018-11-13

申请号：US14208477

申请日：2014-03-13

Applicant: WISYS Technology Foundation, Inc.

Inventor： Jeffrey M. Leismer ,  Nadder D. Sahar

IPC: A61H1/02 ,  A63B69/00 ,  A61H23/02 ,  A63B21/005 ,  A63B23/035 ,  A63B23/04 ,  A63B24/00 ,  A63B21/00 ,  A63B71/00

Abstract: An apparatus for musculoskeletal stimulation allows independent electronic control of vibration parameters and overall biasing force so that an optimum combination of these parameters may be obtained regardless of the user's weight and without the need for adjustment of mechanical weights or springs.

公开(公告)号：US10112881B2

公开(公告)日：2018-10-30

申请号：US15327721

申请日：2015-07-21

Applicant: WiSys Technology Foundation, Inc.

Inventor： Cheng-Chen Huang ,  Aaron P. Monte

IPC: C07C43/23 ,  A61Q19/02 ,  A61K8/34

Abstract: The present invention provides a compound of Formula I, wherein R1 is not H when R2 is H and R2 is not H when R1 is H, further wherein R1 is CnH(2n+1)O, wherein n is 1-10, R2 is OH or CnH(2n+1)O, wherein n is 1-10, A, B and R1, R2, R5, R6, and R7 are separately and independently selected from a group consisting of H, alkyl, hydroxyl, halo, nitro and aryl groups, R11 is an alkyl or an aryl group and L is an optional linker or linking group, with x=0 or 1, i.e., if x=0, no linking group is present, or a salt or prodrug or derivative thereof that is a skin-lightening agent useful for the inhibition of melanin synthesis and/or the removal of existing melanin to function as a skin-lightening agent.

公开(公告)号：US09745621B2

公开(公告)日：2017-08-29

申请号：US15239155

申请日：2016-08-17

Applicant: WISYS Technology Foundation, Inc.

Inventor： Aric Martin Opdahl

IPC: G01N21/55 ,  C12Q1/68 ,  G01N21/64 ,  G01N21/552 ,  G01N21/03 ,  G01N21/27 ,  G01N21/17

CPC classification number: C12Q1/6837 ,  C12Q1/6825 ,  G01N21/0332 ,  G01N21/274 ,  G01N21/553 ,  G01N21/6428 ,  G01N21/648 ,  G01N2021/1731 ,  G01N2201/1211

Abstract: A system and method for sensitive measurements of molecular binding as a function of time and temperature provided by a surface plasmon resonance (SPR) instrument producing a stable temperature gradient over the sensor surface. Continuous monitoring of reflected light intensity from different locations of the sensor allows simultaneous measurement of time and temperature dependence of binding interactions.

公开(公告)号：US09382554B2

公开(公告)日：2016-07-05

申请号：US13952071

申请日：2013-07-26

Applicant: Toivo Kallas ,  Matthew Nelson ,  Eric Singsaas

Inventor： Toivo Kallas ,  Matthew Nelson ,  Eric Singsaas

IPC: C12P5/02 ,  C12P5/00 ,  C12N9/88 ,  C12N9/90

CPC classification number: C12P5/007 ,  C12N9/88 ,  C12N9/90 ,  C12P5/002 ,  C12P5/026 ,  C12Y205/01001 ,  C12Y402/03015 ,  C12Y402/03027 ,  C12Y503/03002 ,  Y02P20/52

Abstract: Methods of isoprenoid production are provided by the present invention. In particular, transgenic Synechococcus sp. PCC 7002 cyanobacteria and methods for producing isoprene and pinene using a host transgenic Synechococcus sp. PCC 7002 cyanobacterium are provided.

Abstract translation: 异戊二烯生产方法由本发明提供。 特别是转基因聚球藻 PCC 7002蓝细菌和使用宿主转基因聚球藻生产异戊二烯和蒎烯的方法。 提供PCC 7002蓝藻。

公开(公告)号：US09381564B2

公开(公告)日：2016-07-05

申请号：US14453285

申请日：2014-08-06

Applicant: WISYS TECHNOLOGY FOUNDATION, INC.

Inventor： Daniel S. McGuire ,  Eric E. Hellmstrom ,  Charles M. Olson

IPC: B22C1/10 ,  B22C9/04 ,  B22C9/10 ,  B22C1/22 ,  B22C1/26 ,  B22C9/02

CPC classification number: B22C1/10 ,  B22C1/22 ,  B22C1/26 ,  B22C9/02 ,  B22C9/04 ,  B22C9/10 ,  B33Y10/00 ,  B33Y80/00

Abstract: A printable refractory material is provided having a liquid and powder component configured for use in a 3-D powder printer, where the material forms hydraulic bonds when the liquid and powder components are combined. Methods of printing the refractory material and forming castings therefrom are also provided.

Abstract translation: 提供了一种可印刷耐火材料，其具有构造成用于3-D粉末打印机的液体和粉末组分，其中当液体和粉末组分组合时材料形成水力粘合。 还提供了打印耐火材料并由其形成铸件的方法。

公开(公告)号：US09084565B2

公开(公告)日：2015-07-21

申请号：US13561537

申请日：2012-07-30

Applicant: Andrea H. Mason ,  Leigh A. Mrotek Gorzek ,  David M. Kettner

Inventor： Andrea H. Mason ,  Leigh A. Mrotek Gorzek ,  David M. Kettner

IPC: A61B5/11

CPC classification number: A61B5/1124 ,  A61B5/11 ,  A61B5/1125 ,  A61B5/1128

Abstract: The invention relates to rehabilitation systems and methods for providing therapy to individuals who have suffered a stroke or other neurological insult. A rehabilitation system may comprise a depth sensing camera positioned to view a workspace into which a patient's hands may be located, a display system viewable by the patient, and an electronic computer executing a stored program to display a representation of a virtual space holding at least one virtual object, display a representation of at least one hand of the patient, and monitor a virtual manipulation of the virtual object by the patient's hand. Other embodiments may include virtual reality goggles, head motion tracking, various exercises and of varying difficulty, tracking metrics and recording for subsequent playback.

Abstract translation: 本发明涉及为遭受中风或其他神经损伤的个体提供治疗的康复系统和方法。 康复系统可以包括定位成查看患者的手可以位于其中的工作空间的深度感测照相机，患者可以看到的显示系统以及执行存储的程序以显示至少保持虚拟空间的表示的电子计算机 一个虚拟对象，显示患者的至少一只手的表示，并且通过患者的手监视虚拟对象的虚拟操纵。 其他实施例可以包括虚拟现实护目镜，头部运动跟踪，各种练习和不同难度，跟踪度量和用于随后重放的记录。

公开(公告)号：US09042975B2

公开(公告)日：2015-05-26

申请号：US13099068

申请日：2011-05-02

Applicant: William D. Gregory

Inventor： William D. Gregory

IPC: A61B5/05 ,  A61B5/053

CPC classification number: A61B5/053

Abstract: A device and method for accurately characterizing tissue impedance employs multiple electrodes at a plurality of separation distances to cancel the effects of front end loading leakage currents and electrode polarization to improve the accuracy of sensitive impedance measurements used to identify cancerous tissues. These measurements may be automated over a range of frequencies.

Abstract translation: 用于准确表征组织阻抗的装置和方法采用多个间隔距离处的多个电极来消除前端负载泄漏电流和电极极化的影响，以提高用于识别癌组织的敏感阻抗测量的精度。 这些测量可以在一定频率范围内自动化。

公开(公告)号：US08467865B2

公开(公告)日：2013-06-18

申请号：US12042425

申请日：2008-03-05

Applicant: William D. Gregory ,  Christopher W. Gregory

Inventor： William D. Gregory ,  Christopher W. Gregory

IPC: A61B5/05

CPC classification number: A61B5/0536 ,  A61B5/4312 ,  A61B5/4842 ,  A61B5/7282

Abstract: A method for characterizing tissues within a subject as cancerous or non-cancerous includes determining the electrical properties of the subject. The electrical properties of the subject are fit to a model and a characteristic frequency of each tissue is then calculated. Each tissue is finally characterized as cancerous or non-cancerous if its characteristic frequency lies above a threshold value.

Abstract translation: 用于将受试者内的组织表征为癌性或非癌性的方法包括确定受试者的电学性质。 受试者的电学性质适合于模型，然后计算每个组织的特征频率。 如果其特征频率高于阈值，则每个组织最终被表征为癌性或非癌性。

公开(公告)号：US08139343B2

公开(公告)日：2012-03-20

申请号：US13041808

申请日：2011-03-07

Applicant: Charles P. Gibson ,  Annamalai Karthikeyan

Inventor： Charles P. Gibson ,  Annamalai Karthikeyan

IPC: H01G9/00

CPC classification number: H01G9/02 ,  H01G9/155 ,  Y02E60/13 ,  Y02T10/7022

Abstract: An electrical energy storage device includes a first electrode; a second electrode; a separator; and an electrolyte; where the separator is an electronic insulator; the separator is positioned between the first and second electrodes; the separator includes a first surface proximal to the first electrode and a second surface proximal to the second electrode; the separator is configured to support an electric double layer at the first surface, the second surface, or at both the first surface and the second surface; and the device is an electrical energy storage device.

Abstract translation: 电能存储装置包括第一电极; 第二电极; 分隔符 和电解质; 其中分离器是电子绝缘体; 分离器位于第一和第二电极之间; 分离器包括靠近第一电极的第一表面和靠近第二电极的第二表面; 隔板构造成在第一表面，第二表面或第一表面和第二表面处支撑双电层; 并且该装置是电能存储装置。

公开(公告)号：US08052930B2

公开(公告)日：2011-11-08

申请号：US12417075

申请日：2009-04-02

Applicant: William D. Gregory

Inventor： William D. Gregory

IPC: G01N21/00

CPC classification number: G01N33/4836 ,  Y10T436/2575

Abstract: A device for characterizing ex vivo tissue employs a set of independent electrodes that may be used to scan the tissue by moving a voltage gradient across the tissue surface acquiring impedance spectrographs that may be mapped to an image.

Abstract translation: 用于表征离体组织的装置采用一组独立电极，其可以用于通过移动组织表面上的电压梯度来扫描组织，获得可映射到图像的阻抗光谱仪。