公开(公告)号：US07713709B2

公开(公告)日：2010-05-11

申请号：US11724983

申请日：2007-03-16

Applicant: Joleen White ,  Lisa Argento Flay ,  Erik Foehr ,  Gary Taniguchi ,  William S. Prince ,  Bin Zhao

Inventor： Joleen White ,  Lisa Argento Flay ,  Erik Foehr ,  Gary Taniguchi ,  William S. Prince ,  Bin Zhao

IPC: G01N33/53

CPC classification number: G01N33/6854 ,  G01N33/573 ,  G01N2333/924

Abstract: The present invention relates to methods for screening body fluids or tissues for antibodies, including neutralizing and isotype-specific antibodies, against lysosomal enzymes administered as part of enzyme replacement therapy.

Abstract translation: 本发明涉及用于针对作为酶替代疗法的一部分而施用的溶酶体酶筛选用于抗体的体液或组织的方法，包括中和和同种型特异性抗体。

公开(公告)号：US20100053915A1

公开(公告)日：2010-03-04

申请号：US12510782

申请日：2009-07-28

Applicant: XIAO-ZHOU WANG ,  ZHEN-GANG DING ,  BIN ZHAO ,  LEI WANG

Inventor： XIAO-ZHOU WANG ,  ZHEN-GANG DING ,  BIN ZHAO ,  LEI WANG

IPC: H05K5/00

CPC classification number: H01R12/7005 ,  G06K13/08

Abstract: An exemplary chip card holder used in a portable electronic device for holding a chip card is provided. The chip card holder includes a body member, a card receiving space disposed on the body member, an elastic piece and a releasing piece. The elastic piece is disposed at one end of the card receiving space and is configured for elastically resisting against the chip card to provide a pushing force to the chip card. The releasing piece is releasably disposed at the other end of the card receiving space opposite to the elastic piece and being configured to hold and release the chip card. The chip card locking device has simple structure and is easy to operate to lock or unlock the chip card.

Abstract translation: 提供了用于保持芯片卡的便携式电子设备中使用的示例性芯片卡保持器。 芯片卡座包括本体构件，设置在主体构件上的卡片容纳空间，弹性片和释放片。 弹性片设置在卡接收空间的一端，并且被配置为弹性抵抗芯片卡以向芯片卡提供推力。 释放片被可释放地设置在与弹性片相对的卡片接收空间的另一端，并被配置为保持和释放芯片卡。 芯片卡锁定装置结构简单，易于操作以锁定或解锁芯片卡。

公开(公告)号：US20090315481A1

公开(公告)日：2009-12-24

申请号：US12363294

申请日：2009-01-30

Applicant: Bin Zhao

Inventor： Bin Zhao

IPC: H05B37/02

CPC classification number: H05B33/0815 ,  H05B33/0857

Abstract: Disclosed are example open channel detection techniques at a light emitting diode (LED) driver of an LED system. The LED driver does not enable its LED channels before normal operation so as to inhibit current flow through the LED channels during start-up. While the LED channels are disabled, the LED driver compares the voltages at the LED channel inputs with a predetermined voltage to determine whether an operational LED string of an associated LED panel is connected to the LED channel. In the event that an LED channel is determined to be an “open” channel, the LED driver further disables the LED channel for the following normal operational mode. Otherwise, if the LED channel is determined to be connected to an operational LED string, the LED driver enables the LED channel for the normal operational mode, during which the LED channel can be selectively activated for light output subject to display data for the LED panel.

Abstract translation: 公开了LED系统的发光二极管（LED）驱动器处的示例性开放通道检测技术。 LED驱动器在正常操作之前不能使能其LED通道，以便在启动期间禁止通过LED通道的电流。 当LED通道被禁用时，LED驱动器将LED通道输入端的电压与预定电压进行比较，以确定相关LED面板的工作LED串是否连接到LED通道。 在LED通道确定为“开路”通道的情况下，LED驱动器进一步禁用LED通道用于以下正常操作模式。 否则，如果LED通道被确定为连接到可操作的LED串，则LED驱动器使得LED通道能够进入正常操作模式，在此期间LED通道可以选择性地激活以进行LED输出的显示数据 。

公开(公告)号：US07584370B2

公开(公告)日：2009-09-01

申请号：US11473351

申请日：2006-06-22

Applicant: Bin Zhao

Inventor： Bin Zhao

IPC: G06F1/26 ,  H03K17/00

CPC classification number: H03K19/018557 ,  H03K17/063 ,  H03K17/102 ,  H03K17/687

Abstract: A semiconductor network is interposed between first and second multiple-port interfaces each having high-voltage, intermediate-voltage and ground ports to form a switch assembly. The assembly includes a primary switch circuit, a support network, internal and external-port circuits and internal and external-port control circuits. The primary switch circuit is coupled to high-voltage ports of the multiple-port interfaces and to the support network. The internal and external-port circuits are coupled to intermediate-voltage ports of the multiple-port interfaces, the internal and external-port control circuits and the support network. The internal-port control circuit is coupled to the internal-port circuit, the support network and a ground port of a first multiple-port interface. The external-port control circuit is coupled to the external-port circuit, the support network and a ground port of the second multiple-port interface. The assembly has a low-leakage current in both open and closed states when exposed to a range of high voltages.

Abstract translation: 半导体网络介于第一和第二多端口接口之间，每个端口具有高电压，中间电压和接地端口以形成开关组件。 组件包括主开关电路，支撑网络，内部和外部端口电路以及内部和外部端口控制电路。 主开关电路耦合到多端口接口的高压端口和支持网络。 内部和外部端口电路耦合到多端口接口的中压端口，内部和外部端口控制电路和支持网络。 内部端口控制电路耦合到内部端口电路，支持网络和第一多端口接口的接地端口。 外部端口控制电路耦合到外部端口电路，支持网络和第二多端口接口的接地端口。 当暴露于一定范围的高电压时，组件在打开和关闭状态都具有低漏电流。

公开(公告)号：US20070279023A1

公开(公告)日：2007-12-06

申请号：US11448651

申请日：2006-06-06

Applicant: Bin Zhao

Inventor： Bin Zhao

IPC: G05F1/00

CPC classification number: H02M3/07

Abstract: According to one exemplary embodiment, a voltage up-conversion circuit includes a modulated voltage generator circuit, where the modulated voltage generator circuit is configured to receive an input voltage and generate a modulated voltage, and where the modulated voltage generator circuit includes at least one transistor. The voltage up-conversion circuit further includes a switching circuit coupled to the modulated voltage generator circuit, where the switching circuit is configured to couple the modulated voltage to a load capacitor when the modulated voltage is at a high level and decouple the modulated voltage to the load capacitor when the modulated voltage is at a low level. In the voltage up-conversion circuit, the load capacitor reaches a voltage greater a breakdown voltage of the at least one transistor in the modulated voltage generator circuit. The breakdown voltage can be a reliability breakdown voltage.

Abstract translation: 根据一个示例性实施例，电压上变换电路包括调制电压发生器电路，其中调制电压发生器电路被配置为接收输入电压并产生调制电压，并且其中调制电压发生器电路包括至少一个晶体管 。 电压上变换电路还包括耦合到调制电压发生器电路的开关电路，其中开关电路被配置为当调制电压处于高电平时将调制电压耦合到负载电容器，并将调制电压去耦到 当调制电压处于低电平时加载电容。 在电压上变换电路中，负载电容器达到调制电压发生器电路中至少一个晶体管的击穿电压更大的电压。 击穿电压可以是可靠性击穿电压。

公开(公告)号：US20050086556A1

公开(公告)日：2005-04-21

申请号：US10987245

申请日：2004-11-12

Applicant: Min Zhu ,  Bin Zhao

Inventor： Min Zhu ,  Bin Zhao

IPC: H04L1/22 ,  H04L29/06 ,  H04L29/08 ,  H04L29/14 ,  G06F15/16

CPC classification number: H04L1/22 ,  H04L67/1002 ,  H04L67/1008 ,  H04L67/1012 ,  H04L67/1029 ,  H04L67/1031 ,  H04L69/40

Abstract: A distributed collaborative computer system is provided that comprises a plurality of server computers interconnected via a high-speed link. Client computers can connect to any available server computer and start or join a conference hosted on either the server computer to which the client computer is connected or any other server in the system. As a result, the system and method of the present invention is easily scalable to support an arbitrary number of participants to a conference by merely adding the appropriate number of server computers to the system. In addition, by replicating the conference information on more than one server computer, the single point of failure limitation is eliminated. In fact, if a server hosting or participating in a conference malfunctions, the failure is detected by other server computers and the client computer is able to reconnect to the conference through a new server computer.

Abstract translation: 提供了一种分布式协同计算机系统，其包括通过高速链路互连的多个服务器计算机。 客户端计算机可以连接到任何可用的服务器计算机，并启动或加入在与客户端计算机连接的服务器计算机或系统中的任何其他服务器上托管的会议。 结果，本发明的系统和方法可以容易地扩展，以通过仅仅将适当数量的服务器计算机添加到系统来支持会议的任意数量的参与者。 另外，通过在多台服务器计算机上复制会议信息，消除了单点故障限制。 事实上，如果托管或参与会议的服务器发生故障，则其他服务器计算机检测到故障，客户端计算机能够通过新的服务器计算机重新连接到会议。

公开(公告)号：US20050013869A1

公开(公告)日：2005-01-20

申请号：US10622316

申请日：2003-07-18

Applicant: Cheng Chaw ,  Yi-Yan Yang ,  Shabbir Moochhala ,  Donna Tan ,  Bin Zhao

Inventor： Cheng Chaw ,  Yi-Yan Yang ,  Shabbir Moochhala ,  Donna Tan ,  Bin Zhao

IPC: A61K9/16 ,  A61K9/22 ,  A61K9/50

CPC classification number: A61K9/1647

Abstract: The invention provides microparticles for sustained release formulation for physostigmine, pyridostigmine and other therapeutically active carbamates. The microparticles comprise the active compound and a biodegradable polymer such as polyester, poly(phosphate), poly(anhydride), poly(ortho ester), or mixture thereof. In one embodiment, the polymer is poly(d,l-lactide-co-glycolide). The desired release pattern of the active compound may be readily attained by varying the type and amount of the polymer used, including by using a mixture of two polymers, one of which is more hydrophobic. The invention also provides a method of preparing the microparticles and in one embodiment, the microparticles may be prepared by spray drying.

Abstract translation: 本发明提供用于毒扁豆黄素，吡斯的明和其他治疗活性氨基甲酸酯的持续释放制剂的微粒。 微粒包括活性化合物和可生物降解的聚合物如聚酯，聚（磷酸酯），聚（酸酐），聚（原酸酯）或其混合物。 在一个实施方案中，聚合物是聚（d，l-丙交酯 - 共 - 乙交酯）。 通过改变所用聚合物的类型和量可以容易地获得所需的活性化合物的释放模式，包括通过使用两种聚合物的混合物，其中一种是更疏水的。 本发明还提供了制备微粒的方法，在一个实施方案中，微粒可以通过喷雾干燥制备。

公开(公告)号：US06821485B2

公开(公告)日：2004-11-23

申请号：US10071846

申请日：2002-02-08

Applicant: David J. Beebe ,  Jeffrey S. Moore ,  Bin Zhao

Inventor： David J. Beebe ,  Jeffrey S. Moore ,  Bin Zhao

IPC: B01L302

CPC classification number: B82Y30/00 ,  B01L3/5027 ,  B01L3/502707 ,  B01L2300/089 ,  B01L2400/0672 ,  Y10T436/11 ,  Y10T436/117497 ,  Y10T436/118339 ,  Y10T436/2575

Abstract: A flow of liquids is carried out on a microscale utilizing surface effects to guide the liquid on flow paths to maintain laminar flow. No sidewall confining structure is required, minimizing resistance to flow and allowing laminar flow to be maintained at high flow rates. The guiding structure has flow guiding stripes formed on one or both of facing base and cover surfaces which are wettable by a selected liquid to direct the liquid from a source location to a destination location. The regions adjacent to the guiding stripes on the base and cover surfaces are non-wettable. The smooth interface between the gas and liquid along the flowing stream allows gas-liquid reactions to take place as a function of diffusion across the interface without mixing of the gas and liquid. Liquid-liquid flows may also be guided with such structures.

Abstract translation: 使用表面效应在微尺度上进行液体流动以将液体引导到流动路径上以保持层流。 不需要侧壁约束结构，使流动阻力最小化，并允许层流维持在高流速。 引导结构具有形成在一个或两个相对的基底和盖表面上的流动引导条纹，其可被选定的液体润湿以将液体从源位置引导到目的地位置。 在基部和盖表面上与引导条相邻的区域是不可润湿的。 沿着流动流动的气体和液体之间的平滑界面允许气 - 液反应作为扩散跨越界面而发生，而不会混合气体和液体。 液 - 液流也可以用这种结构引导。

公开(公告)号：US06740985B1

公开(公告)日：2004-05-25

申请号：US09716350

申请日：2000-11-20

Applicant: Bin Zhao

Inventor： Bin Zhao

IPC: H01L2348

CPC classification number: H01L24/05 ,  H01L24/03 ,  H01L2224/02166 ,  H01L2224/04042 ,  H01L2224/05093 ,  H01L2224/05556 ,  H01L2224/05647 ,  H01L2224/45124 ,  H01L2224/45144 ,  H01L2224/48647 ,  H01L2224/48747 ,  H01L2924/00014 ,  H01L2924/01005 ,  H01L2924/01006 ,  H01L2924/01013 ,  H01L2924/01014 ,  H01L2924/01015 ,  H01L2924/01019 ,  H01L2924/01023 ,  H01L2924/01027 ,  H01L2924/01029 ,  H01L2924/01033 ,  H01L2924/01039 ,  H01L2924/01063 ,  H01L2924/01068 ,  H01L2924/01073 ,  H01L2924/01074 ,  H01L2924/01079 ,  H01L2924/01082 ,  H01L2924/01084 ,  H01L2924/04953 ,  H01L2924/05042 ,  H01L2924/14 ,  H01L2924/30105 ,  H01L2924/00

Abstract: A copper bonding pad is directly supported by a copper via pad structure, the copper via pad structure having substantially the same geometry and dimensions as the copper bonding pad. The combination of the copper bonding pad and the copper via pad structure results in an increase in effective thickness of the copper bonding pad. Due to this effective increase in the bonding pad thickness, the bonding pad is more tolerant to the potential dishing problem caused by the CMP process. Additional metal pad structures and via pad structures are used below the bonding pad. The additional metal pad structures and via pad structures comprise alternating segments of interconnect metal and dielectric fillers, and alternating segments of via metal and dielectric fillers, respectively. The alternating segments of interconnect metal and dielectric fillers and the alternating segments of via metal and dielectric fillers prevent or reduce the potential dishing problem that otherwise exists in damascene and CMP processing. The alternating segments of interconnect metal and dielectric fillers and the alternating segments of via metal and dielectric fillers are arranged such that there are a number of columns of solid metal support under the bonding pad. The columns of solid metal support significantly improve the poor mechanical support otherwise provided by the low dielectric constant materials that are presently used in fabrication of modern copper integrated circuits. The columns of solid metal support also improve thermal conductivity of the bonding pad.

Abstract translation: 铜焊盘由铜通孔焊盘结构直接支撑，铜通孔焊盘结构具有与铜焊盘基本上相同的几何形状和尺寸。 铜焊盘和铜通孔焊盘结构的组合导致铜焊盘的有效厚度的增加。 由于焊盘厚度的这种有效增加，焊盘更能承受由CMP工艺引起的潜在的凹陷问题。 在焊盘下面使用附加的金属焊盘结构和通孔焊盘结构。 附加的金属焊盘结构和通孔焊盘结构分别包括互连金属和介电填料的交替段，以及通孔金属和电介质填料的交替段。 互连金属和电介质填料的交替段和通孔金属和电介质填料的交替段防止或减少在镶嵌和CMP加工中存在的潜在凹陷问题。 互连金属和电介质填料的交替段和通孔金属和电介质填料的交替段布置成使得在接合焊盘下方有许多固体金属支撑柱。 固体金属载体的柱显着地改善了目前用于制造现代铜集成电路的低介电常数材料提供的差的机械支撑。 固体金属载体的柱也提高了焊盘的导热性。

公开(公告)号：US06684006B2

公开(公告)日：2004-01-27

申请号：US10021472

申请日：2001-12-07

Applicant: Bin Zhao

Inventor： Bin Zhao

IPC: G02B628

CPC classification number: G02B6/2938 ,  G02B6/29353 ,  G02B6/29355 ,  G02B6/29386 ,  H04J14/02

Abstract: A dispersion mitigating interleaver assembly has a first unbalanced Mach-Zehnder interferometer (MZI) assembly which includes first and second output ports and which has first transmission vs. wavelength curve and a first dispersion vs. wavelength curve. The dispersion mitigating interleaver assembly also includes a second unbalanced MZI assembly which has a second transmission vs. wavelength curve and a second dispersion vs. wavelength curve. The second unbalanced MZI assembly receives an output from one of the first and second output ports of the first unbalanced MZI assembly. The second transmission vs. wavelength curve is substantially the same as the first transmission vs. wavelength curve and the second dispersion vs. wavelength curve is substantially opposite with respect to the first dispersion vs. wavelength curve, such that dispersion is substantially cancelled by the cooperation of the first and second unbalanced MZI assemblies.

Abstract translation: 分散减轻交错器组件具有第一不平衡马赫 - 曾德干涉仪（MZI）组件，其包括第一和第二输出端口，并且具有第一透射与波长曲线以及第一色散与波长曲线。 色散减轻交错器组件还包括第二不平衡MZI组件，其具有第二透射与波长曲线和第二色散相对于波长曲线。 第二不平衡MZI组件从第一不平衡MZI组件的第一和第二输出端口之一接收输出。 第二透射率与波长曲线基本上与第一透射率相对于波长曲线相同，并且第二色散对波长曲线相对于第一色散相对于波长曲线基本相反，使得色散基本上被合作消除 的第一和第二不平衡MZI组件。