公开(公告)号：US20110154581A1

公开(公告)日：2011-06-30

申请号：US13044466

申请日：2011-03-09

Applicant: Manoj Kumar ,  Susan M. Madrid ,  Hugh C. McDonald ,  Ayrookaran J. Poulose ,  Thomas Rand ,  Huaming Wang

Inventor： Manoj Kumar ,  Susan M. Madrid ,  Hugh C. McDonald ,  Ayrookaran J. Poulose ,  Thomas Rand ,  Huaming Wang

IPC: D06L1/16 ,  C07H21/00 ,  C12N15/63 ,  C12N1/21 ,  C12N9/02 ,  C11D3/60

CPC classification number: C12N9/0006 ,  C07K2319/02 ,  C11D3/38654 ,  C12Y101/03

Abstract: The present invention provides compositions and methods for producing a polyol oxidase in micoroorganisms, and the use of polyol oxidases in cleaning compositions. The invention includes cleaning compositions that contain combinations of two or more POx oxidases, and cleaning compositions that contain combinations of two or more POx oxidases and a perhydrolase. In particular, the invention provides methods for expressing polyol oxidases in bacterial hosts for use in detergent applications for cleaning, bleaching and disinfecting.

Abstract translation: 本发明提供用于在微生物中生产多元醇氧化酶的组合物和方法，以及在清洁组合物中使用多元醇氧化酶。 本发明包括含有两种或更多种POx氧化酶的组合的清洁组合物和含有两种或更多种POx氧化酶和过水解酶的组合的清洁组合物。 特别地，本发明提供了用于在洗涤剂应用中用于清洁，漂白和消毒的细菌宿主中表达多元氧化酶的方法。

公开(公告)号：US20100273718A1

公开(公告)日：2010-10-28

申请号：US12519317

申请日：2007-12-03

Applicant: Manoj Kumar ,  David Wong

Inventor： Manoj Kumar ,  David Wong

IPC: A61K38/00 ,  C07K14/00 ,  C07K7/06 ,  C07K7/08 ,  A23J1/00 ,  A23L2/00 ,  A61K8/64 ,  A61Q19/10

CPC classification number: A23J3/343 ,  A23C9/1209 ,  A23C21/02 ,  A23L33/18 ,  A61K8/64 ,  A61Q19/02 ,  C12Y304/21019

Abstract: Hydrolyzate compositions comprising at least one milk protein or whey hydrolyzed with at least one proteolytic enzyme are provided. The hydrolyzates reduce the immunogenicity of the milk or whey protein in a subject predisposed to having an immune reaction to the protein. Methods for making the compositions are also provided, as food products and nonfood products comprising the compositions.

Abstract translation: 提供包含至少一种乳蛋白或用至少一种蛋白水解酶水解的乳清的水解物组合物。 水解物降低了倾向于对蛋白质具有免疫反应的受试者的乳或乳清蛋白的免疫原性。 还提供了制备组合物的方法，作为包含组合物的食品和非食品。

公开(公告)号：US07691806B2

公开(公告)日：2010-04-06

申请号：US11351712

申请日：2006-02-10

Applicant: Katherine D. Collier ,  William A. Cuevas ,  Manoj Kumar

Inventor： Katherine D. Collier ,  William A. Cuevas ,  Manoj Kumar

IPC: A61K38/00 ,  C07K14/00 ,  C07K17/00 ,  A23J1/00 ,  C07K16/00 ,  C07K1/00 ,  A61K51/00

CPC classification number: A61K8/64 ,  A61K38/00 ,  A61K47/59 ,  A61K47/64 ,  A61K2800/57 ,  A61Q13/00 ,  A61Q17/04 ,  C07K14/21 ,  C07K14/415 ,  C07K14/43504 ,  C07K14/43586 ,  C07K14/4716 ,  C07K14/4727 ,  C07K14/4741 ,  C07K14/78 ,  C07K2319/00 ,  C08H1/00 ,  C08H1/06

Abstract: Biomolecular conjugates are provided which comprise the conjugation product of a repeat sequence protein polymer and at least one active agent. Additional aspects provide methods for their manufacture and various industrial and consumer applications.

Abstract translation: 提供了包含重复序列蛋白质聚合物和至少一种活性剂的缀合产物的生物分子缀合物。 其他方面提供了其制造方法和各种工业和消费者应用。

公开(公告)号：US20090307743A1

公开(公告)日：2009-12-10

申请号：US12134933

申请日：2008-06-06

Applicant: Alain C. Azagury ,  Murthy V. Devarakonda ,  Nikolai Joukov ,  Manoj Kumar ,  Konstantinos Magoutis ,  Birgit M. Pfitzmann ,  Norbert G. Vogl

Inventor： Alain C. Azagury ,  Murthy V. Devarakonda ,  Nikolai Joukov ,  Manoj Kumar ,  Konstantinos Magoutis ,  Birgit M. Pfitzmann ,  Norbert G. Vogl

IPC: G06F21/00

CPC classification number: G06F21/604 ,  G06F2221/2101

Abstract: A method, system, computer program product, and computer program storage device for transforming a high-level policy associated with a high layer to a low-level policy associated with a low layer. Mapping between high-level objects in a high layer and low-level objects in a low layer is derived by an automated discovery tool. The high-level policy is mapped to the low-level policy according to the mapping (e.g., by substituting the high-level objects with the low-level objects and by performing a syntax transformation). In one embodiment, a low-level policy is transformed to a high-level policy according to the mapping. As exemplary embodiments, policy transformations in traffic shaping and data retention are disclosed.

Abstract translation: 一种用于将与高层相关联的高级策略变换为与低层相关联的低级策略的方法，系统，计算机程序产品和计算机程序存储设备。 高层的高层对象与低层对象之间的映射是通过自动发现工具得出的。 高级策略根据映射映射到低级策略（例如，通过用低级对象替换高级对象，并通过执行语法转换）。 在一个实施例中，根据映射将低级策略转换为高级策略。 作为示例性实施例，公开了流量整形和数据保持中的策略转换。

公开(公告)号：US20090280071A1

公开(公告)日：2009-11-12

申请号：US11860911

申请日：2007-09-25

Applicant: Manoj Kumar ,  William A. Cuevas

Inventor： Manoj Kumar ,  William A. Cuevas

IPC: A61K8/64 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q11/00 ,  A61Q15/00 ,  A61Q3/02 ,  A61Q3/04 ,  A61Q5/02 ,  A61Q9/02

CPC classification number: A61K8/0212 ,  A61K8/0229 ,  A61K8/64 ,  A61K38/1709 ,  A61K2800/28 ,  A61Q1/02 ,  A61Q1/04 ,  A61Q1/06 ,  A61Q1/10 ,  A61Q1/12 ,  A61Q3/00 ,  A61Q3/02 ,  A61Q5/006 ,  A61Q5/02 ,  A61Q5/12 ,  A61Q17/04 ,  A61Q19/00 ,  A61Q19/001 ,  A61Q19/002 ,  A61Q19/10

Abstract: A personal care composition is provided and includes an effective amount of a repeat sequence protein polymer. The personal care composition may be a hair care composition, a skin care composition, a nail care composition, a cosmetic composition, or an over-the-counter pharmaceutical composition.

Abstract translation: 提供个人护理组合物并且包括有效量的重复序列蛋白质聚合物。 个人护理组合物可以是护发组合物，护肤组合物，指甲护理组合物，化妆品组合物或非处方药物组合物。

公开(公告)号：US07617122B2

公开(公告)日：2009-11-10

申请号：US10230910

申请日：2002-08-28

Applicant: Manoj Kumar ,  Parul A Mittal ,  Natwar Modani ,  Amit Anil Nanavati ,  Biplav Srivastava

Inventor： Manoj Kumar ,  Parul A Mittal ,  Natwar Modani ,  Amit Anil Nanavati ,  Biplav Srivastava

IPC: G06Q30/00

CPC classification number: G06Q30/02 ,  G06Q30/0201 ,  G06Q30/0239 ,  G06Q30/0254 ,  G06Q30/0255 ,  G06Q30/0259 ,  G06Q30/0263 ,  G06Q30/0271

Abstract: Selecting one or more marketing messages for optimal display at marketing locations in a marketing environment is performed on the basis of information relating to a user to whom the messages are to be displayed, the marketing messages, and the marketing locations. Dynamic selection and display of marketing messages in this manner can be advantageously performed for online environments for which relevant information is readily accessed and used as a basis for selection and display of marketing messages.

Abstract translation: 在营销环境中的营销位置选择一个或多个营销消息以最佳展示是基于与要显示消息的用户相关的信息，营销消息和营销位置来执行的。 以这种方式动态地选择和显示营销消息可以有利地执行用于相关信息容易被访问并用作营销消息的选择和显示的基础的在线环境。

公开(公告)号：US20090217571A1

公开(公告)日：2009-09-03

申请号：US12091913

申请日：2005-10-28

Applicant: Mahendra Pratap Singh ,  Manoj Kumar ,  Wadhava Ram Kalsi ,  Alex Cheru Pulikottil ,  Rakesh Sarin ,  Deepak Kumar Tuli ,  Ravinder Kumar Malhotra ,  Ram Prakash Verma ,  Brij Mohan Bansal

Inventor： Mahendra Pratap Singh ,  Manoj Kumar ,  Wadhava Ram Kalsi ,  Alex Cheru Pulikottil ,  Rakesh Sarin ,  Deepak Kumar Tuli ,  Ravinder Kumar Malhotra ,  Ram Prakash Verma ,  Brij Mohan Bansal

IPC: C10L1/18 ,  C10G32/00

CPC classification number: C10G32/00 ,  C10G21/16 ,  C10G27/04 ,  C10G27/12 ,  C10G53/04 ,  C10G53/14 ,  C10G2400/02 ,  C10G2400/04 ,  C10G2400/06

Abstract: Disclosed herein is a method for producing ultra-low-sulfur content hydrocarbon fuel and product thereof. The method comprises selective biocatalytic oxidation of sulfur containing compounds present in the fuels employing enzyme lipase as biocatalyst in presence of controlled and incremental amount of hydrogen peroxide and carboxylic acid without using water or any co-factor for the reactivity of said enzymes.

Abstract translation: 本文公开了一种生产超低硫含量烃燃料的方法及其产物。 该方法包括在控制和增量的过氧化氢和羧酸的存在下，使用酶脂肪酶作为生物催化剂，存在于燃料中的含硫化合物的选择性生物催化氧化，而不使用水或任何辅因子用于所述酶的反应性。

公开(公告)号：US20080293611A1

公开(公告)日：2008-11-27

申请号：US11875788

申请日：2007-10-19

Applicant: Manoj Kumar ,  Susan M. Madrid ,  Hugh C. McDonald ,  Ayrookaran J. Poulose ,  Thomas Rand ,  Huaming Wang

Inventor： Manoj Kumar ,  Susan M. Madrid ,  Hugh C. McDonald ,  Ayrookaran J. Poulose ,  Thomas Rand ,  Huaming Wang

IPC: C11D7/42 ,  C12N15/11 ,  C12N15/00 ,  C12N1/20 ,  C12P21/04

CPC classification number: C12N9/0006 ,  C07K2319/02 ,  C11D3/38654 ,  C12Y101/03

Abstract: The present invention provides compositions and methods for producing a polyol oxidase in micoroorganisms, and the use of polyol oxidases in cleaning compositions. The invention includes cleaning compositions that contain combinations of two or more POx oxidases, and cleaning compositions that contain combinations of two or more POx oxidases and a perhydrolase. In particular, the invention provides methods for expressing polyol oxidases in bacterial hosts for use in detergent applications for cleaning, bleaching and disinfecting.

Abstract translation: 本发明提供用于在微生物中生产多元醇氧化酶的组合物和方法，以及在清洁组合物中使用多元醇氧化酶。 本发明包括含有两种或更多种POx氧化酶的组合的清洁组合物和含有两种或更多种POx氧化酶和过水解酶的组合的清洁组合物。 特别地，本发明提供了用于在洗涤剂应用中用于清洁，漂白和消毒的细菌宿主中表达多元氧化酶的方法。

公开(公告)号：US07419795B2

公开(公告)日：2008-09-02

申请号：US10842929

申请日：2004-05-10

Applicant: Timothy C. Dodge ,  Manoj Kumar ,  M. Harunur Rashid ,  Fernando Valle

Inventor： Timothy C. Dodge ,  Manoj Kumar ,  M. Harunur Rashid ,  Fernando Valle

IPC: G01N33/53

CPC classification number: C12P7/58 ,  C07K14/24 ,  C12P7/60

Abstract: The present invention relates to engineering metabolic pathways in bacterial host cells which results in enhanced carbon flow for the production of ascorbic acid (ASA) intermediates. In particular, the invention relates to increasing the production of ASA intermediates in bacterial cells by enhancing the availability of gluconate resulting from the inactivation of endogenous gluconate transporter genes.

Abstract translation: 本发明涉及在细菌宿主细胞中工程代谢途径，其导致用于生产抗坏血酸（ASA）中间体的增强的碳流。 特别地，本发明涉及通过增加由内源性葡萄糖酸转运蛋白基因失活产生的葡萄糖酸盐的可利用性来增加细菌细胞中ASA中间体的产生。

公开(公告)号：US07328185B1

公开(公告)日：2008-02-05

申请号：US09721093

申请日：2000-11-22

Applicant: Manish Gupta ,  Anant D. Jhingran ,  Manoj Kumar ,  Karthikeyan Seetharaman

Inventor： Manish Gupta ,  Anant D. Jhingran ,  Manoj Kumar ,  Karthikeyan Seetharaman

IPC: G06Q40/00

CPC classification number: G06Q40/00 ,  G06Q10/02 ,  G06Q40/04

Abstract: A method and apparatus for generating bids for bidding agents in an auction. Bids are sorted by decreasing bid amount for regular bids and upper limit for order bids to form a sorted set of bids, wherein each bid includes a quantity and wherein the bids include order bids. A first bid is identified requesting a quantity in which an unallocatable portion is present. A number of order bids is selected from the bids, wherein the number of order bids are higher in the sorted set of bids than the first bid and have an allocation requirement less than the unallocatable portion of the of the first bid. A price is set for the order bids higher than the first bid and not in the aforementioned selected bids.

Abstract translation: 一种用于在拍卖中为出价代理人生成出价的方法和装置。 出价根据定期出价的出价金额和订单出价的上限进行排序，以形成一组排序的出价，其中每个出价包括数量，其中出价包括订单出价。 标识出第一个出价，要求其中存在不可分配部分的数量。 从出价中选择多个订单出价，其中订单出价的数量在排序的出价集合中比第一投标更高，并且分配要求小于第一投标的不可分配部分。 订单出价高于第一个出价的价格，而不是在上述选定的出价中。