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    Array level Fourier ptychographic imaging
    112.
    发明授权
    Array level Fourier ptychographic imaging 有权

    公开(公告)号：US09829695B2

    公开(公告)日：2017-11-28

    申请号：US15007196

    申请日：2016-01-26

    Applicant: California Institute of Technology

    Inventor： Jinho Kim ,  Changhuei Yang

    IPC: G02B21/36 ,  G02B21/16 ,  G02B21/00 ,  G01N21/64

    CPC classification number: G02B21/365 ,  G01N21/6452 ,  G01N21/6456 ,  G01N21/6458 ,  G01N2021/6478 ,  G01N2201/0446 ,  G02B13/0095 ,  G02B21/0076 ,  G02B21/16 ,  G02B21/367 ,  H04N5/22541 ,  H04N5/2256 ,  H04N5/2258

    Abstract: In one aspect an imaging system includes: an illumination system including an array of light sources; an optical system including one or more lens arrays, each of the lens arrays including an array of lenses, each of the lenses in each of the one or more lens arrays in alignment with a corresponding set of light sources of the array of light sources; an imaging system including an array of image sensors, each of the image sensors in alignment with a corresponding lens or set of lenses of the one or more lens arrays, each of the image sensors configured to acquire image data based on the light received from the corresponding lens or set of lenses; a plate receiver system capable of receiving a multi-well plate including an array of wells, the plate receiver system configured to align each of the wells with a corresponding one of the image sensors; and a controller configured to control the illumination of the light sources and the acquisition of image data by the image sensors, the controller further configured to perform: an image acquisition process including a plurality of scans, each scan associated with a unique pattern of illumination, each of the image sensors configured to generate an image for a respective one of the wells during each scan; and an image reconstruction process during which the controller performs a fourier ptychographic operation to generate a reconstructed image for each of the wells based on the image data captured for the respective well during each of the scans.

    LIQUID AND PLATE SENSORS FOR MICROPLATE INJECTOR SYSTEM
    115.
    发明申请
    LIQUID AND PLATE SENSORS FOR MICROPLATE INJECTOR SYSTEM 有权
    液体和板式传感器用于微型注射器系统

    公开(公告)号：US20160169808A1

    公开(公告)日：2016-06-16

    申请号：US14566708

    申请日：2014-12-10

    Applicant: Molecular Devices, LLC

    Inventor： Josef J. Atzler ,  Michael Katzlinger ,  Georg Kronberger ,  Bernhard Schinwald

    IPC: G01N21/76

    CPC classification number: G01N21/76 ,  G01J3/02 ,  G01N21/15 ,  G01N21/253 ,  G01N21/763 ,  G01N27/223 ,  G01N35/028 ,  G01N2021/015 ,  G01N2021/155 ,  G01N2035/1025 ,  G01N2201/0225 ,  G01N2201/0245 ,  G01N2201/0446 ,  G01N2201/0806

    Abstract: In a sample analyzing apparatus, an injector assembly injects a reagent onto a sample, and luminescent light from the sample is transmitted to a detector. The assembly may be movable toward and away from the sample. The assembly may include one or more needles that communicate with one or more reservoirs supplying reagent or other liquids. The assembly may include a light guide for communicating with the detector. A cartridge may be provided in which the assembly, one or more reservoirs, and one or more pumps are disposed. The cartridge and/or the apparatus may be configured for enabling rinsing or priming to be done outside the apparatus. The cartridge and/or the apparatus may include one or more types of sensors configured for detecting, for example, the presence of liquid or bubbles in one or more locations of the apparatus and/or the cartridge.

    Abstract translation: 在样品分析装置中，注射器组件将试剂注射到样品上，并将来自样品的发光发射到检测器。 组件可以朝向和远离样品移动。 组件可以包括与供应试剂或其它液体的一个或多个储存器连通的一个或多个针。 组件可以包括用于与检测器通信的光导。 可以提供盒，其中设置组件，一个或多个储存器和一个或多个泵。 墨盒和/或设备可以被配置为使得能够在设备外进行冲洗或启动。 药筒和/或装置可以包括一种或多种类型的传感器，其被配置用于例如在装置和/或药筒的一个或多个位置中检测液体或气泡的存在。

    SYSTEM AND METHOD FOR DETERMINING A CONCENTRATION OF A COMPOUND IN A SOLVENT
    116.
    发明申请
    SYSTEM AND METHOD FOR DETERMINING A CONCENTRATION OF A COMPOUND IN A SOLVENT 有权
    用于测定溶剂中化合物浓度的系统和方法

    公开(公告)号：US20160161399A1

    公开(公告)日：2016-06-09

    申请号：US15046354

    申请日：2016-02-17

    Applicant: Engineered Medical Technologies

    Inventor： Bryan John Cowger ,  Megan Anzar Babb ,  Peichen Chang

    IPC: G01N21/33 ,  G01J1/42 ,  G01N21/01

    CPC classification number: G01N21/33 ,  G01J1/42 ,  G01N21/03 ,  G01N21/13 ,  G01N21/31 ,  G01N2021/0367 ,  G01N2021/1751 ,  G01N2201/0446 ,  G01N2201/062

    Abstract: The present describes a system and method for determining the concentration of tetrahydrocannabinol (THC) including a tray comprising a first analyte including an infusion of a solvent and cannabis, a light emitting element configured to illuminate the first analyte, a light receiving element configured to receive a first light transmitted through the first analyte, and a control circuit configured to calculate a concentration of tetrahydrocannabinol in the first analyte based at least in part on the first light.

    Abstract translation: 本发明描述了一种用于测定四氢大麻酚（THC）的浓度的系统和方法，所述系统和方法包括包含第一分析物的托盘，所述第一分析物包括溶剂和大麻的输注，被配置为照射所述第一分析物的发光元件，被配置为接收 透射通过第一分析物的第一光;以及控制电路，被配置为至少部分地基于第一光计算第一分析物中的四氢大麻酚的浓度。

    Microplate-reader with a controlled gas atmosphere and a corresponding method of controlling the gas atmosphere
    118.
    发明申请
    Microplate-reader with a controlled gas atmosphere and a corresponding method of controlling the gas atmosphere 审中-公开
    具有受控气体气氛的微孔板读数器和控制气体气体的相应方法

    公开(公告)号：US20160018429A1

    公开(公告)日：2016-01-21

    申请号：US14870673

    申请日：2015-09-30

    Applicant: TECAN Trading AG

    Inventor： Florian REINER ,  Harald GEBETHSROITHER ,  Josef GRASSL

    IPC: G01N35/02 ,  G01N21/25 ,  G01N21/64

    CPC classification number: G01N35/028 ,  B01L9/52 ,  C12M1/04 ,  C12M41/14 ,  C12M41/16 ,  C12Q1/02 ,  G01J3/12 ,  G01N21/253 ,  G01N21/6452 ,  G01N33/5005 ,  G01N2035/00356 ,  G01N2201/023 ,  G01N2201/0231 ,  G01N2201/0238 ,  G01N2201/0446 ,  G01N2201/06113

    Abstract: The invention relates to a microplate reader and a respective method, wherein the microplate reader comprises at least one measuring device and a holding device for accommodating at least one microplate and for positioning the samples-containing wells of this(these) microplate(s) in relation to the at least one measuring device. The at least one measuring device is used for detecting light which is emitted by samples in wells of a microplate inserted in this microplate reader and/or which is influenced by samples transilluminated by light in wells of a microplate inserted in this microplate reader. The microplate reader comprises a control unit for controlling the temperature of a gas atmosphere surrounding the wells containing the samples of microplates used in this microplate reader.

    Abstract translation: 本发明涉及一种酶标仪和相应的方法，其中该酶标仪包括至少一个测量装置和用于容纳至少一个微孔板的保持装置，并将该（微）微孔板的含样品的孔定位在 与至少一个测量装置的关系。 所述至少一个测量装置用于检测由插入该酶标板读数器中的微孔板的孔中的样品发出的光，和/或由插入该酶标板读数器中的微板的孔中的光透过的样品影响。 酶标仪包括用于控制包含在该酶标板读数器中使用的微孔板样品的孔周围的气体气氛的温度的控制单元。

    Illumination Systems
    120.
    发明申请
    Illumination Systems 审中-公开
    照明系统

    公开(公告)号：US20150185152A1

    公开(公告)日：2015-07-02

    申请号：US14420647

    申请日：2013-08-09

    Applicant: LIFE TECHNOLOGIES CORPORATION

    Inventor： Kevin Maher

    IPC: G01N21/64

    CPC classification number: G01N21/6486 ,  G01N21/6452 ,  G01N2021/6463 ,  G01N2201/0446 ,  G01N2201/062 ,  G01N2201/0631

    Abstract: A system for detecting emissions from a sample containing nucleotide molecules contains a sample holder, an optical illumination system, an optical sensor. The sample holder includes a plurality of spatially separated reaction sites configured to hold a sample containing nucleotide molecules. The optical illumination system comprising a radiant source configured to simultaneously illuminate two or more of the reaction sites. The illumination system includes a homogenizer. An output from the homogenizer has less variation in power, energy, irradiance, or intensity than the variation in power, energy, irradiance, or intensity of the source.

    Abstract translation: 用于检测含有核苷酸分子的样品的发射的系统包含样品架，光学照明系统，光学传感器。 样品架包括多个空间分离的反应位点，其配置成容纳含有核苷酸分子的样品。 光学照明系统包括被配置为同时照亮两个或更多个反应位点的辐射源。 照明系统包括均质器。 来自均化器的输出与功率，能量，辐照度或源的强度的变化相比，功率，能量，辐照度或强度的变化较小。

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