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公开(公告)号：US09757061B2
公开(公告)日：2017-09-12
申请号：US14842276
申请日：2015-09-01
Applicant: DexCom, Inc.
Inventor： Mark Shults , Rathbun K. Rhodes , Stuart J. Updike , James H. Brauker
IPC: A61B5/05 , A61B5/1486 , A61B5/145
CPC classification number: A61B5/14532 , A61B5/0002 , A61B5/0031 , A61B5/145 , A61B5/14503 , A61B5/14865 , A61B5/1495 , A61B5/150022 , A61B5/6846
Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.
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公开(公告)号：US09750460B2
公开(公告)日：2017-09-05
申请号：US15488190
申请日：2017-04-14
Applicant: DexCom, Inc.
Inventor： Paul V. Goode , James H. Brauker , Arpurv U. Kamath , James Patrick Thrower , Victoria Carr-Brendel
IPC: A61B5/00 , A61B5/05 , A61B5/145 , A61B5/1486 , A61B5/1495
CPC classification number: A61B5/7203 , A61B5/0004 , A61B5/0031 , A61B5/14532 , A61B5/14539 , A61B5/14542 , A61B5/1473 , A61B5/14865 , A61B5/1495 , A61B5/7225 , A61B5/7257 , A61B5/726 , A61B5/7278 , A61B5/742 , A61B5/7475 , A61B2560/0223 , A61B2562/0247 , A61B2562/0271 , A61B2562/08
Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.
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公开(公告)号：US20170150910A1
公开(公告)日：2017-06-01
申请号：US15429022
申请日：2017-02-09
Applicant: DexCom, Inc.
Inventor： James R. Petisce , Mark A. Tapsak , Peter C. Simpson , Victoria Carr-Brendel , James H. Brauker
IPC: A61B5/1473 , A61B5/1486 , A61B5/145
CPC classification number: A61B5/1473 , A61B5/145 , A61B5/14503 , A61B5/14532 , A61B5/14546 , A61B5/1468 , A61B5/14735 , A61B5/14865
Abstract: The present invention relates generally to systems and methods for increasing oxygen availability to implantable devices. The preferred embodiments provide a membrane system configured to provide protection of the device from the biological environment and/or a catalyst for enabling an enzymatic reaction, wherein the membrane system includes a polymer formed from a high oxygen soluble material. The high oxygen soluble polymer material is disposed adjacent to an oxygen-utilizing source on the implantable device so as to dynamically retain high oxygen availability to the oxygen-utilizing source during oxygen deficits. Membrane systems of the preferred embodiments are useful for implantable devices with oxygen-utilizing sources and/or that function in low oxygen environments, such as enzyme-based electrochemical sensors and cell transplantation devices.
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公开(公告)号：US20170076068A1
公开(公告)日：2017-03-16
申请号：US15362571
申请日：2016-11-28
Applicant: DexCom, Inc.
Inventor： John Michael Dobbles , Apurv Ullas Kamath , Aarthi Mahalingam , James H. Brauker
CPC classification number: A61M5/1723 , A61B5/0031 , A61B5/14532 , A61B5/14546 , A61M5/003 , A61M5/14244 , A61M5/14276 , A61M5/178 , A61M5/20 , A61M5/30 , A61M11/00 , A61M15/00 , A61M15/0065 , A61M15/0068 , A61M15/008 , A61M15/0083 , A61M35/00 , A61M2005/14296 , A61M2205/3569 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/587 , A61M2205/8206 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H40/63
Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.
Abstract translation: 提供了用于集成包括接收器14，药物输送装置16，控制器模块和任选的单点葡萄糖监测器18的连续葡萄糖传感器12的系统和方法。 集成可以是手动，半自动化和/或完全自动化。
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公开(公告)号：US09463277B2
公开(公告)日：2016-10-11
申请号：US14144360
申请日：2013-12-30
Applicant: DexCom, Inc.
Inventor： John Michael Dobbles , Apurv Ullas Kamath , Aarthi Mahalingam , James H. Brauker
IPC: A61M5/172 , A61B5/145 , A61M5/142 , G06F19/00 , A61B5/00 , A61M5/00 , A61M5/178 , A61M5/30 , A61M11/00 , A61M15/00
CPC classification number: A61M5/1723 , A61B5/0031 , A61B5/14532 , A61B5/14546 , A61M5/003 , A61M5/14244 , A61M5/14276 , A61M5/178 , A61M5/20 , A61M5/30 , A61M11/00 , A61M15/00 , A61M15/0065 , A61M15/0068 , A61M15/008 , A61M15/0083 , A61M35/00 , A61M2005/14296 , A61M2205/3569 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/587 , A61M2205/8206 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H40/63
Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.
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Patent Agency Ranking
公开(公告)号：US20140303465A1
公开(公告)日：2014-10-09
申请号：US14281697
申请日：2014-05-19
Applicant: DexCom, Inc.
Inventor： Peter C. Simpson , James H. Brauker
IPC: A61B5/145 , A61B5/1486
CPC classification number: A61B5/14532 , A61B5/0031 , A61B5/1486 , A61B5/14865 , B33Y80/00 , C12Q1/001 , C12Q1/006
Abstract: Disclosed herein is an analyte sensing biointerface that comprises a sensing electrode incorporated within a non-conductive matrix comprising a plurality of passageways extending through the matrix to the sensing electrode. Also disclosed herein are methods of manufacturing a sensing biointerface and methods of detecting an analyte within tissue of a host using an analyte sensing biointerface.
Abstract translation: 本文公开了一种分析物感测生物界面，其包括结合在非导电矩阵内的感测电极，其包括穿过矩阵延伸到感测电极的多个通道。 本文还公开了制造感测生物接口的方法和使用分析物感测生物接口来检测主体组织内的分析物的方法。
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公开(公告)号：US20140275900A1
公开(公告)日：2014-09-18
申请号：US14290842
申请日：2014-05-29
Applicant: DexCom, Inc.
Inventor： Mark Shults , James H. Brauker , Victoria Carr-Brendel , Mark Tapsak , Dubravka Markovic
IPC: A61B5/1486 , A61B5/145
CPC classification number: A61B5/14865 , A61B5/14532 , A61L31/10 , A61L31/14 , A61L31/146 , A61L31/16 , A61L2300/00 , B33Y80/00 , G01N33/48707
Abstract: A biointerface membrane for an implantable device including a nonresorbable solid portion with a plurality of interconnected cavities therein adapted to support tissue ingrowth in vivo, and a bioactive agent incorporated into the biointerface membrane and adapted to modify the tissue response is provided. The bioactive agents can be chosen to induce vascularization and/or prevent barrier cell layer formation in vivo, and are advantageous when used with implantable devices wherein solutes are transported across the device-tissue interface.
Abstract translation: 一种用于可植入装置的生物界面膜，其包括不可再吸收的固体部分，其具有适于在体内支持组织向内生长的多个相互连接的空腔，以及并入生物界面膜中并适于修饰组织反应的生物活性剂。 可以选择生物活性剂以诱导血管形成和/或预防体内阻隔细胞层形成，并且当与其中溶质被输送穿过装置 - 组织界面的可植入装置一起使用时是有利的。
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公开(公告)号：US20140128803A1
公开(公告)日：2014-05-08
申请号：US14144360
申请日：2013-12-30
Applicant: DexCom, Inc.
Inventor： John Michael Dobbles , Apurv Ullas Kamath , Aarthi Mahalingam , James H. Brauker
IPC: A61M5/172
CPC classification number: A61M5/1723 , A61B5/0031 , A61B5/14532 , A61B5/14546 , A61M5/003 , A61M5/14244 , A61M5/14276 , A61M5/178 , A61M5/20 , A61M5/30 , A61M11/00 , A61M15/00 , A61M15/0065 , A61M15/0068 , A61M15/008 , A61M15/0083 , A61M35/00 , A61M2005/14296 , A61M2205/3569 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/587 , A61M2205/8206 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H40/63
Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.
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公开(公告)号：US20140052092A1
公开(公告)日：2014-02-20
申请号：US14063790
申请日：2013-10-25
Applicant: DexCom, Inc.
Inventor： John Michael Dobbles , Apurv Ullas Kamath , Aarthi Mahalingam , James H. Brauker
IPC: A61M5/172
CPC classification number: A61M5/1723 , A61B5/0031 , A61B5/14532 , A61B5/14546 , A61M5/003 , A61M5/14244 , A61M5/14276 , A61M5/178 , A61M5/20 , A61M5/30 , A61M11/00 , A61M15/00 , A61M15/0065 , A61M15/0068 , A61M15/008 , A61M15/0083 , A61M35/00 , A61M2005/14296 , A61M2205/3569 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/587 , A61M2205/8206 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H40/63
Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.
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公开(公告)号：US20140052091A1
公开(公告)日：2014-02-20
申请号：US14063753
申请日：2013-10-25
Applicant: DexCom, Inc.
Inventor： John Michael Dobbles , Apurv Ullas Kamath , Aarthi Mahalingam , James H. Brauker
IPC: A61M5/172
CPC classification number: A61M5/1723 , A61B5/0031 , A61B5/14532 , A61B5/14546 , A61M5/003 , A61M5/14244 , A61M5/14276 , A61M5/178 , A61M5/20 , A61M5/30 , A61M11/00 , A61M15/00 , A61M15/0065 , A61M15/0068 , A61M15/008 , A61M15/0083 , A61M35/00 , A61M2005/14296 , A61M2205/3569 , A61M2205/50 , A61M2205/502 , A61M2205/52 , A61M2205/581 , A61M2205/582 , A61M2205/587 , A61M2205/8206 , A61M2230/201 , G06F19/00 , G06F19/3468 , G16H40/63
Abstract: Systems and methods for integrating a continuous glucose sensor 12, including a receiver 14, a medicament delivery device 16, a controller module, and optionally a single point glucose monitor 18 are provided. Integration may be manual, semi-automated and/or fully automated.
Abstract translation: 提供了用于集成包括接收器14，药物输送装置16，控制器模块和任选的单点葡萄糖监测器18的连续葡萄糖传感器12的系统和方法。 集成可以是手动，半自动化和/或完全自动化。
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