Compositions for coloring the skin based on indole derivatives
    131.
    发明授权
    Compositions for coloring the skin based on indole derivatives 失效
    基于吲哚衍生物着色皮肤的组合物

    公开(公告)号:US4956174A

    公开(公告)日:1990-09-11

    申请号:US21931

    申请日:1987-03-05

    CPC classification number: A61Q19/04 A61K8/492

    Abstract: Cosmetic composition designed to impart to the skin a coloring which is substantially similar to the pigmentation resulting from natural tanning, characterized in that it contains, in a cosmetically acceptable medium suitable for topical application, at least one compound of the formula: ##STR1## in which R.sub.1 denotes a hydrogen atom, a lower alkyl group or a residue --SiR.sub.9 R.sub.10 R.sub.11, R.sub.2 and R.sub.3, which may be identical or different, denote a hydrogen atom, a lower alkyl group, a carboxyl group, a lower alkoxycarbonyl group or a group --COOSiR.sub.9 R.sub.10 R.sub.11 ; R.sub.4 and R.sub.5 which may be identical or different, denote a hydrogen atom, a linear or branched C.sub.1 -C.sub.20 alkyl group, a formyl group, a linear or branched C.sub.2 -C.sub.20 acyl group, a linear or branched C.sub.3 -C.sub.20 alkenoyl group, a group R.sub.6 OSO.sub.2 --, a group --SiR.sub.9 R.sub.10 R.sub.11, a group --P(O)(OR.sub.6).sub.2 or an aralkyl group, or alternatively R.sub.4 and R.sub.5, with the oxygen atoms to which they are attached, form a ring optionally containing a carbonyl group when at least one of the groups, R.sub.1, R.sub.2 or R.sub.3 is other than hydrogen or alternatively a thiocarbonyl group, a residue >P(O)OR.sub.6, a group >CR.sub.7 R.sub.8 or a methylene group, R.sub.6 denoting a hydrogen atom or a lower alkyl group, R.sub.7 denoting a hydrogen atom or a lower alkyl group, R.sub.8 denoting a lower alkoxy group or a mono- or dialkylamino group and R.sub.9, R.sub.10 or R.sub.11, which may be identical or different, denoting linear or branched lower alkyl groups, at least one of the substituents R.sub.1, R.sub.2, R.sub.3, R.sub.4 and R.sub.5 being other than hydrogen; and the corresponding salts with alkali metals, alkaline earth metals, ammonium or amines.

    Abstract translation: 化妆品组合物被设计成赋予皮肤一种基本上类似于由天然鞣制引起的色素沉着的着色,其特征在于其在适合局部应用的化妆品可接受的介质中包含至少一种下式的化合物: I),其中R 1表示氢原子,低级烷基或残基-SiR 9 R 10 R 11,R 2和R 3可以相同或不同,表示氢原子,低级烷基,羧基,低级烷氧基羰基或 一组-COOSiR9R10R11; 可以相同或不同的R 4和R 5表示氢原子,直链或支链C 1 -C 20烷基,甲酰基,直链或支链C 2 -C 20酰基,直链或支链C 3 -C 20链烯酰基, 基团R6OSO2-,基团-SiR9R10R11,基团-P(O)(OR6)2或芳烷基,或者R4和R5与它们所连接的氧原子形成任选含有羰基的环, R 1,R 2或R 3中的至少一个不是氢或硫代羰基,残基> P(O)OR 6,基团> CR 7 R 8或亚甲基,R 6表示氢原子或低级烷基 ,R7表示氢原子或低级烷基,R8表示低级烷氧基或单或二烷基氨基,R9,R10或R11可以相同或不同,表示直链或支链的低级烷基,至少一个 的取代基R 1,R 2,R 3,R 4和R 5不是氢; 和与碱金属,碱土金属,铵或胺的相应的盐。

    Quaternized polymer for use as a cosmetic agent in cosmetic compositions
for the hair and skin
    132.
    发明授权
    Quaternized polymer for use as a cosmetic agent in cosmetic compositions for the hair and skin 失效
    用作头发和皮肤的化妆品组合物中的化妆品的季铵化聚合物

    公开(公告)号:US4948579A

    公开(公告)日:1990-08-14

    申请号:US545770

    申请日:1983-10-26

    Abstract: A quaternized polymer for use as a cosmetic agent, has recurring units of the formula ##STR1## wherein R is lower alkyl or --CH.sub.2 --CH.sub.2 OH;R' is an aliphatic, alicyclic or arylaliphatic radical containing a maximum of 20 carbon atoms, or R and R' together with the nitrogen atom to which they are attached form a heterocycle capable of containing a heteroatom other than nitrogen;A is a divalent group selected from(1) o-, m- or p-xylylidene of the formula ##STR2## (2) ##STR3## wherein x, y and t are whole numbers ranging from 0 to 11 such that the sum (x+y+t) is greater than or equal to 0 and lower than 18, and E and K represent hydrogen or an aliphatic radical having less than 18 carbon atoms,(3) --(CH.sub.2).sub.n --S--(CH.sub.2).sub.n --,(4) --(CH.sub.2).sub.n --O--(CH.sub.2).sub.n --,(5) --(CH.sub.2).sub.n --S--S--(CH.sub.2).sub.n --,(6) --(CH.sub.2).sub.n --SO--(CH.sub.2).sub.n --,(7) --(CH.sub.2).sub.n --SO.sub.2 --(CH.sub.2).sub.n -- and(8) ##STR4## wherein n is equal to 2 or 3; B represents a divalent group selected from(1) o-, m- or p-xylylidene of the formula ##STR5## (2) ##STR6## wherein D and G represent hydrogen or an aliphatic radical having less than 18 carbon atoms and v, z, and u are whole numbers ranging from 0 to 11, with two of v, z and u simultaneously being capable of being 0, such that the sum (v+z+u) is greater than or equal to 1 and lower than 18 and such that the sum (v+z+u) is greater than 1 when the sum (x+y+t) is equal to 0,(3) ##STR7## and (4) --(CH.sub.2).sub.n --O--(CH.sub.2).sub.n -- wherein n is 2 or 3; andX.crclbar. is an anion derived from an organic or mineral acid. The quaternized polymer is employed in cosmetic compositions for the hair and skin.

    Abstract translation: 用作化妆剂的季铵化聚合物具有下式的重复单元:其中R是低级烷基或-CH 2 -CH 2 OH; R'是含有最多20个碳原子的脂族,脂环族或芳基脂族基团,或者R和R'与它们所连接的氮原子一起形成能够含有氮以外的杂原子的杂环; A是选自(1)式(2)的(1)邻 - ,间 - 或对 - 亚二甲苯基的二价基团,其中x,y和t是0至11的整数,使得 x + y + t)大于或等于0且低于18,并且E和K表示氢或具有少于18个碳原子的脂族基团,(3) - (CH2)nS-(CH2)n-, (4) - (CH2)nO-(CH2)n-,(5) - (CH2)nSS-(CH2)n-,(6) - (CH2)n-SO-(CH2)n-,(7) - (CH 2)n -SO 2 - (CH 2)n - 和(8)其中n等于2或3; B表示选自(1)式(2)的(1)邻 - ,间 - 或对 - 亚二甲苯基的二价基团,其中D和G表示氢或具有少于18个碳原子的v, z和u是从0到11的整数,v,z和u中的两个同时能够为0,使得和(v + z + u)大于或等于1并低于18 并且当和(x + y + t)等于0时,和(4) - (CH2)nO-(CH2)的和(v + z + u) 其中n为2或3; 而X( - )是衍生自有机或无机酸的阴离子。 季铵化聚合物用于头发和皮肤的化妆品组合物中。

    Polyaminoamides which filter ultraviolet radiation, process for their
preparation and their use in the protection of the skin and hair
    137.
    发明授权
    Polyaminoamides which filter ultraviolet radiation, process for their preparation and their use in the protection of the skin and hair 失效
    过滤紫外线辐射的聚氨基酰胺,其制备过程及其在保护皮肤和头发中的用途

    公开(公告)号:US4866159A

    公开(公告)日:1989-09-12

    申请号:US899888

    申请日:1986-08-25

    Abstract: Polyaminoamides of formula: ##STR1## in which A.sub.1 represents a divalent radical of structure: ##STR2## in which a and b=0 or 1 ##STR3## in which c and d=0 or 1 or ##STR4## B.sub.1 represents: (1) in the proportions of 60 to 100% (in moles), the radical ##STR5## in which x.sub.1 =2 and n.sub.1 =1 or 2, or alternatively, x.sub.1 =3 and n.sub.1 =1 and e=0 or 1(2) in the proportions of 0 to 40% (in moles), the radical (II) above in which x.sub.1 =2 and n.sub.1 =0 or the radical ##STR6## (3) in the proportions of 0 to 20% (in moles), the radical--NH--(CH.sub.2).sub.6 --NH--;in radicals A.sub.1 and B.sub.1, Y represents a residue of an ultraviolet radiation-absorbing molecule, anda+b+c+d+e.gtoreq.1,it being understood that when a, b, c, d or e are zero, the nitrogen atom is then bound to a hydrogen atom;the ratio m/p is between 0.05 and 0.5;A.sub.2 represents a bivalent radical which has one of the following structures: ##STR7## B.sub.2 represents: (1) in the proportions of 60 to 100% (in moles), the radical ##STR8## in which x.sub.2 =2 and n.sub.2 =2 or 3, or alternatively, x.sub.2 =3 and n.sub.2 =2(2) in the proportions of 0 to 40% (in moles), the radical (III) above in which x.sub.2 =2 and n.sub.2 =1 or the radical ##STR9## (3) in the proportions of 0 to 20% (in moles), the radical--NH--(CH.sub.2).sub.6 --NH--process for their preparation and their use as sunlight filters for hair and skin.

    Abstract translation: 其中A 1表示结构如下的二价基团:其中a和b = 0或1 其中c和d = 0或1或的下式的聚氨基酰胺: > B1表示:(1)以60至100%(以摩尔计)的比例,其中x1 = 2和n1 = 1或2,或者备选地,x1 = 3且n1 = 1的基团(II) 和以0至40%(以摩尔数计)的比例为e = 0或1(2),其中x1 = 2和n1 = 0的上述基团(II)或基团的比例(3) 0至20%(以摩尔计),基团-NH-(CH 2)6 -NH-; 在基团A1和B1中,Y表示紫外线吸收分子的残基,+ b + c + d + e> / = 1,应理解当a,b,c,d或e为零时, 然后氮原子与氢原子结合; 比率m / p在0.05和0.5之间; A2表示具有以下结构之一的二价基团:B2表示:(1)以60至100%(以摩尔数计)的比例,基团( III),其中x2 = 2和n2 = 2或3,或者以0至40%(以摩尔数计)的比例,x2 = 3和n2 = 2(2),上述基团(III),其中x2 = 2和n2 = 1或基团(3)以0至20%(以摩尔计)的比例,用于其制备的自由基-NH-(CH 2)6 -NH-方法及其用作阳光过滤器 头发和皮肤。

    Dyeing compositions for keratinous fibres, especially for human hair,
containing oxidation dye precursors and heterocyclic couplers
    138.
    发明授权
    Dyeing compositions for keratinous fibres, especially for human hair, containing oxidation dye precursors and heterocyclic couplers 失效
    含有氧化染料前体和杂环成色剂的角质纤维特别是人毛的染色组合物

    公开(公告)号:US4865617A

    公开(公告)日:1989-09-12

    申请号:US92720

    申请日:1987-09-03

    CPC classification number: C07D317/66 A61K8/4973 A61Q5/10 C07D317/46

    Abstract: The invention relates to a dyeing composition for keratinous fibres containing, in a cosmetically acceptable solvent medium, at least one para-type oxidation dye precursor in combination with at least one heterocyclic coupler of formula: ##STR1## in which R denotes a hydrogen atom, a C.sub.1 -C.sub.4 radical, a C.sub.2 -C.sub.4 hydroxyalkyl radical, a C.sub.3 to C.sub.6 polyhydroxyalkyl radical, or a C.sub.2 -C.sub.6 alkoxyalkyl radical, Z, independently of R, denotes a C.sub.1 to C.sub.4 alkyl radical, a C.sub.2 to C.sub.4 hydroxyalkyl radical, a C.sub.3 to C.sub.6 polyhydroxyalkyl radical, a C.sub.2 -C.sub.6 alkoxyalkyl radical or a trifluoroethyl radical, R.sub.1 and R.sub.2 independently of each other denote a hydrogen atom or a C.sub.1 to C.sub.4 alkyl radical, or one of the addition salts of the compound of formula (I) with an inorganic acid, a process for the oxidation dyeing of hair using this composition as well as the new couplers of formula (I) where Z is other than methyl when R.sub.1, R.sub.2 and R=H, the process for their preparation, the new intermediate compounds of formula: ##STR2## and the process for their preparation.

    Abstract translation: 本发明涉及一种用于角蛋白纤维的染色组合物,其在化妆品可接受的溶剂介质中含有至少一种对位型氧化染料前体与至少一种下式的杂环偶联剂:其中R表示 氢原子,C 1 -C 4基团,C 2 -C 4羟基烷基,C 3至C 6多羟基烷基或C 2 -C 6烷氧基烷基,Z独立地表示C 1至C 4烷基,C 2至C 4羟基烷基 自由基,C3至C6多羟基烷基,C2-C6烷氧基烷基或三氟乙基,R1和R2彼此独立地表示氢原子或C1至C4烷基,或式(I)化合物的加成盐之一 (I)的无机酸,使用该组合物进行毛发氧化染色的方法以及式(I)的新型成色剂,其中当R1,R2和R = H时Z不同于甲基,其制备方法 ,新的中间体化合物:

    3-amino-4-nitrophenols, the process for preparation thereof and their
use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols
    140.
    发明授权
    3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols 失效
    3-氨基-4-硝基苯酚,其制备方法及其在染色角质纤维中的用途,以及新的中间体4,5-二硝基酚

    公开(公告)号:US4740622A

    公开(公告)日:1988-04-26

    申请号:US850695

    申请日:1986-04-11

    CPC classification number: A61K8/418 A61Q5/065 C07C205/37 C07D317/62 C09B51/00

    Abstract: New 3-amino-4-nitrophenols, the process for preparation thereof and their use in dyeing keratinous fibres, and new intermediate 4,5-dinitrophenols.The present invention relates to a 3-amino-4-nitrophenol of formula: ##STR1## where Z denotes --CH.sub.2 --W, W denoting hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 hydroxyalkyl, C.sub.2 -C.sub.6 polyhydroxyalkyl, (C.sub.1 -C.sub.3)alkoxy(C.sub.1 -C.sub.6)alkyl or (C.sub.1 -C.sub.3)hydroxyalkoxy(C.sub.1 -C.sub.6)alkyl and R denotes hydrogen, C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 hydroxyalkyl, C.sub.2 -C.sub.6 polyhydroxyalkyl or (C.sub.1 -C.sub.3)alkoxy(C.sub.1 -C.sub.6)alkyl, the process for preparation thereof and the intermediate compound of formula: ##STR2## in which Z' denotes CH.sub.2 --W, W denoting C.sub.1 -C.sub.6 hydroxyalkyl, C.sub.2 -C.sub.6 polyhydroxyalkyl, (C.sub.1 -C.sub.3)alkoxy-(C.sub.1 -C.sub.6)alkyl or (C.sub.1 -C.sub.3)hydroxyalcoxy(C.sub.1 -C.sub.6)alkyl.The dyes (I) are useful in direct dyeing of keratinous fibres, in particular human hair.

    Abstract translation: 新的3-氨基-4-硝基苯酚,其制备方法及其在染色角质纤维中的用途,以及新的中间体4,5-二硝基酚。 本发明涉及下式的3-氨基-4-硝基苯酚:其中Z表示-CH 2 -W,W表示氢,C 1 -C 6烷基,C 1 -C 6羟烷基,C 2 -C 6多羟基烷基(( C1-C3)烷氧基(C1-C6)烷基或(C1-C3)羟基烷氧基(C1-C6)烷基,R表示氢,C1-C6烷基,C1-C6羟基烷基,C2-C6多羟基烷基或(C1-C3) (C 1 -C 6)烷基,其制备方法和下式的中间体化合物:其中Z'表示CH2-W,W表示C1-C6羟基烷基,C2-C6多羟基烷基,(C1- C3)烷氧基 - (C1-C6)烷基或(C1-C3)羟基烷氧基(C1-C6)烷基。 染料(I)可用于直角染色角质纤维,特别是人类头发。

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