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公开(公告)号:US11883295B2
公开(公告)日:2024-01-30
申请号:US16935555
申请日:2020-07-22
发明人: Brian S. Conklin
CPC分类号: A61F2/2496 , A61B5/1076 , A61B5/6869 , A61F2/2445 , A61F2/2472 , A61B5/107 , A61B5/6852 , A61B90/06 , A61B2090/0807 , A61F2250/001 , A61F2250/0097
摘要: A dynamic, adjustable annuloplasty ring sizer can include an adjustable ring replica, which can be adjusted through a range of sizes corresponding to available prosthetic annuloplasty repair ring sizes. Actuation of an adjustment trigger on a handle portion of the ring sizer can displace tension wires that extend through a malleable shaft and through a plurality of articulating segments that form the ring replica. Displacement of the tension wires causes flexion of the joints between adjacent articulating segments, thereby reducing the overall size of the ring replica. Releasing the tension wires can allow an elastic extension wire to act on the ring replica, enlarging the ring replica to its maximum, at-rest size. In this manner, the appropriate size of annuloplasty ring prosthesis can be determined with a single device, without requiring a plurality of static ring sizers that require individual insertion and placement for the conventional trial-and-error sizing methods.
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公开(公告)号:US20230293294A1
公开(公告)日:2023-09-21
申请号:US18324900
申请日:2023-05-26
发明人: Brian S. Conklin , Qinggang Zeng
IPC分类号: A61F2/24
CPC分类号: A61F2/2418 , A61F2/2409 , A61F2/2433 , A61F2210/0004 , A61F2210/0057 , A61F2220/0075 , A61F2230/0052 , A61F2230/0054 , A61F2230/0067 , A61F2250/001 , A61F2250/0012 , A61F2250/0018 , A61F2250/0021 , A61F2250/0039 , A61F2250/0048 , A61F2250/0089
摘要: A hybrid prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be expanded post implant in order to receive and/or support an expandable prosthetic heart valve therein (a valve-in-valve procedure). The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible for delivery and expandable post-implant to facilitate a valve-in-valve procedure.
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公开(公告)号:US11717404B2
公开(公告)日:2023-08-08
申请号:US16936364
申请日:2020-07-22
发明人: Brian S. Conklin , Derrick Johnson
CPC分类号: A61F2/2427 , A61B17/00234 , A61B2017/00398 , A61B2017/00407 , A61B2017/00477 , A61F2/2418 , A61F2/9517
摘要: Valve holders and introducers for delivering a prosthetic heart valve to an implant site are in various embodiments configured to facilitate insertion of prosthetic valves through small incisions or access sites on a patient's body. The valve holders can also be configured to reduce or eliminate the occurrence of suture looping or other damage to the prosthetic valve during implantation. A valve holder according to embodiments of the invention includes features that reduce or eliminate mistakes during implantation of the prosthetic valves, such as a removable activator dial and a removable handle that prevent implantation of the valve prior to proper deployment or adjustment of the holder. An introducer is provided which can facilitate passing of a prosthetic valve between adjacent ribs of a patient. Valve holders and introducers according to the various embodiments can be used in minimally invasive procedures, such as thoracotomy procedures.
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公开(公告)号:US11707280B2
公开(公告)日:2023-07-25
申请号:US17404931
申请日:2021-08-17
IPC分类号: A61B17/10 , A61B17/068 , A61B17/064 , A61B17/122 , A61B17/128
CPC分类号: A61B17/10 , A61B17/064 , A61B17/068 , A61B17/128 , A61B17/1222 , A61B17/105 , A61B2017/0645 , A61B2017/0649
摘要: Devices and methods for deploying self-cinching surgical clips. A device can access at least two layers of tissue or material from only one side of the tissue or material and puncture through the two layers of tissue or material. The various configurations of clips disclosed herein can be made of a superelastic material such as Nitinol, and have a constrained and a relaxed state, and no sharp edges or tips so as to reduce tissue irritation following deployment. The clip can be disposed within the housing of the delivery device and held in a constrained state until deployment wherein the clip assumes its relaxed state, where the ends of the clip can be brought into close approximation, thereby securing the layers of tissue or material together.
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公开(公告)号:US11690714B2
公开(公告)日:2023-07-04
申请号:US16914255
申请日:2020-06-26
发明人: Brian S. Conklin , Qinggang Zeng
IPC分类号: A61F2/24
CPC分类号: A61F2/2418 , A61F2/2409 , A61F2/2433 , A61F2210/0004 , A61F2210/0057 , A61F2220/0075 , A61F2230/0052 , A61F2230/0054 , A61F2230/0067 , A61F2250/001 , A61F2250/0012 , A61F2250/0018 , A61F2250/0021 , A61F2250/0039 , A61F2250/0048 , A61F2250/0089
摘要: A hybrid prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be expanded post implant in order to receive and/or support an expandable prosthetic heart valve therein (a valve-in-valve procedure). The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible for delivery and expandable post-implant to facilitate a valve-in-valve procedure.
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公开(公告)号:US20230181320A1
公开(公告)日:2023-06-15
申请号:US18167720
申请日:2023-02-10
发明人: Louis A. Campbell , Rodolfo Rodriguez , Da-Yu Chang , Gregory Bak-Boychuk , Brian S. Conklin , Amy E. Munnelly
IPC分类号: A61F2/24
CPC分类号: A61F2/2448 , A61F2250/0029 , A61F2250/0036
摘要: A mitral repair annuloplasty ring that will accommodate implantation of a transcatheter valve therein for a valve-in-ring reoperation. The ring has a semi-rigid core with features that allow the ring to better conform to the cylindrical geometry of a transcatheter valve when implanted. The inner core defines a continuous peripheral D-shape with a substantially straight anterior side diametrically across from a more rounded posterior side with arcuate lateral sides therebetween. Segments of the ring core are subject to differing rates of bending due to variable radial thicknesses or radial slits opening to both inner and outer edges around the core periphery. One or more expansion joints may also be used to create the more circular final expanded shape. A plastically expandable sealing sleeve may surround the transcatheter valve for sealing gaps between the valve and annuloplasty ring.
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公开(公告)号:US20230157820A1
公开(公告)日:2023-05-25
申请号:US18150133
申请日:2023-01-04
发明人: Da-Yu Chang , Amy E. Munnelly , Van Huynh , Avina Gupta , Brian S. Conklin , Sooji Van Echten , Kurt Kelly Reed , Amanda Grace Sall
IPC分类号: A61F2/24
CPC分类号: A61F2/2427 , A61F2/2409 , A61F2/2412 , A61F2/2418 , A61F2220/0075
摘要: A prosthetic heart valve has a plurality of valve leaflets that control directional flow of blood through a heart and a stent structure having a plurality of commissure posts supporting the valve leaflets. The stent structure has a covering over the plurality of commissure posts and has a sewing ring at an inflow end of the stent structure. Each of the plurality of commissure posts has a tip and a suture loop is attached to the covering at a location adjacent to or on the tip of the commissure post. Each suture loop provides a passage for a suture to pass through between the covering and the suture loop.
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公开(公告)号:US11654020B2
公开(公告)日:2023-05-23
申请号:US16666331
申请日:2019-10-28
IPC分类号: A61F2/24
CPC分类号: A61F2/2418 , A61F2/2409 , A61F2210/0057 , A61F2220/0075 , A61F2230/0069 , A61F2250/001 , A61F2250/006 , A61F2250/0018 , A61F2250/0048 , A61F2250/0097
摘要: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander. An inflow stent frame is expandable for anchoring the valve in place, and may have an outflow end that is collapsible to a limited degree for delivery and expandable post-implant to facilitate valve-in-valve (ViV) procedures. The hybrid heart valves eliminate earlier structural bands, which both reduces manufacturing time and facilitates ViV procedures.
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公开(公告)号:US11571299B2
公开(公告)日:2023-02-07
申请号:US16921901
申请日:2020-07-06
发明人: Hengchu Cao , Brian S. Conklin , Paul A. Schmidt , Grace Myong Kim , James A. Davidson , Hoa Trinh Tran , Kristy Luong Tam
IPC分类号: A61F2/24
摘要: Disclosed prosthetic valves can comprise a sewing ring configured to secure the valve to an implantation site. Some disclosed valves comprise a resiliently collapsible frame having a neutral configuration and a collapsed deployment configuration. Some disclosed frames can self-expand to the neutral configuration when released from the collapsed deployment configuration. Collapsing a disclosed valve can provide convenient access to the sewing ring, such as for securing the valve to the implantation site, as well as for the insertion of the valve through relatively small surgical incisions.
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公开(公告)号:US11554012B2
公开(公告)日:2023-01-17
申请号:US17806928
申请日:2022-06-14
发明人: Da-Yu Chang , Amy E. Munnelly , Van Huynh , Avina Gupta , Brian S. Conklin , Sooji Van Echten , Kurt Kelly Reed , Amanda Grace Sall
IPC分类号: A61F2/24
摘要: A prosthetic heart valve has a plurality of valve leaflets that control directional flow of blood through a heart and a stent structure having a plurality of commissure posts supporting the valve leaflets. The stent structure has a covering over the plurality of commissure posts and has a sewing ring at an inflow end of the stent structure. Each of the plurality of commissure posts has a tip and a suture loop is attached to the covering at a location adjacent to or on the tip of the commissure post. Each suture loop provides a passage for a suture to pass through between the covering and the suture loop.
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