公开(公告)号：US20170241127A1

公开(公告)日：2017-08-24

申请号：US15506905

申请日：2015-09-25

Applicant: STC.UNM

Inventor： Timothy Jack Ross

IPC: E04B1/41 ,  E04B1/26

CPC classification number: E04B1/40 ,  E04B1/26 ,  E04B1/2604 ,  E04B2001/266 ,  E04B2001/2668 ,  E04B2001/268 ,  E04B2001/2684

Abstract: The present invention provides a construction system for connecting bamboo segments or poles together, where the segments or poles have non-uniform diameters. The system includes elbow connectors, sleeve connectors, T-shaped connectors and six cavity connectors. Also, part of the connectors include connector segments including an opening defined by a plurality of opposingly located arms separated by one or more channels, and at least one hoop-compression clamp adapted to be positioned around the arms. The arms and hoop-compression clamp cooperate to compress the arms against the bamboo segment to secure bamboo segment within the connector opening.

公开(公告)号：US20170199205A1

公开(公告)日：2017-07-13

申请号：US15463274

申请日：2017-03-20

Applicant: STC.UNM

Inventor： Ke Jian Liu ,  Wenlan Liu ,  Graham Timmins ,  Rong Pan

IPC: G01N33/68

CPC classification number: G01N33/6893 ,  G01N2333/4703 ,  G01N2800/2871 ,  G01N2800/52

Abstract: Methods and apparatus for determining blood brain barrier (BBB)damage and treating patients who may have suffered from BBB damage due to an ischemic event are provided. The methods and apparatus involve detecting the presence of cleaved occludin fragments in a sample of blood. According to some embodiments, the method further provides determining the degree of BBB damage based on the concentration of occludin fragments in the sample. In further embodiments the present disclosure provides kits for detecting the presence of occludin fragments in a blood sample.

公开(公告)号：US09655553B2

公开(公告)日：2017-05-23

申请号：US14850221

申请日：2015-09-10

Applicant: STC.UNM

Inventor： John B. Plumley ,  Erin D. Milligan ,  Marek Osinski

IPC: A61B5/1455 ,  G01N33/58 ,  A61B5/1459 ,  A61B5/00 ,  A61B5/1473

CPC classification number: A61B5/1455 ,  A61B5/1459 ,  A61B5/14735 ,  A61B5/4058 ,  A61B5/6852 ,  A61B5/6877 ,  A61B2562/0233 ,  A61B2562/0285 ,  G01N33/588

Abstract: The invention provides a quantum dot (QD) modified optical fiber-based biosensor which characterizes matrix metalloproteinase (MMP) enzyme activity at pain signaling sites in the central nervous system (CNS) in vivo. Related systems and peptide biomarker screening methods are also provided.

公开(公告)号：US09653793B2

公开(公告)日：2017-05-16

申请号：US14373974

申请日：2013-03-15

Applicant: STC.UNM

Inventor： Youssef A Tawk ,  Christos G Christodoulou ,  Joseph Costantine ,  Maria Elizabeth Zamudio Moreno

IPC: H01Q1/50 ,  H01Q15/24 ,  H01Q13/08 ,  H01Q1/24

CPC classification number: H01Q1/50 ,  H01Q1/24 ,  H01Q13/085 ,  H01Q15/24

Abstract: Embodiments relate to systems and methods for a frequency reconfigurable filtenna system. Implementations incorporate a reconfigurable band-pass filter within the feeding line of an antenna structure. The combination of the filter and the antenna may be referred to as a “filtenna”. Implementations integrate both the band-pass filter and the antenna within the same substrate, permitting easier, more efficient and more compact integration in the transceiver hardware. Moreover, by using this configuration, the biasing of the switching elements are not present in the radiating plane of the antenna. This reduces the negative effect of the biasing lines on the antenna radiation performance, as we!! as provides a tunable filtered antenna radiation characteristic.

公开(公告)号：US20170108375A1

公开(公告)日：2017-04-20

申请号：US15317592

申请日：2015-06-09

Applicant: STC.UNM

Inventor： Steven R.J. BRUECK ,  Alexander NEUMANN ,  Payman ZARKESH-HA

IPC: G01J1/06 ,  G01J3/18 ,  G01J1/44 ,  H01L27/144 ,  G02B6/124 ,  H01L31/103 ,  H01L31/02 ,  H01L31/0216 ,  G02B6/122 ,  G02B6/12 ,  G01J3/28 ,  H01L31/0232

CPC classification number: G01J1/06 ,  G01J1/44 ,  G01J3/0218 ,  G01J3/0259 ,  G01J3/18 ,  G01J3/1895 ,  G01J3/2803 ,  G01J2001/448 ,  G02B6/12004 ,  G02B6/122 ,  G02B6/124 ,  G02B2006/12061 ,  G02B2006/12107 ,  G02B2006/12138 ,  H01L27/1446 ,  H01L31/02019 ,  H01L31/02164 ,  H01L31/02327 ,  H01L31/103

Abstract: A 2-D sensor array includes a semiconductor substrate and a plurality of pixels disposed on the semiconductor substrate. Each pixel includes a coupling region and a junction region, and a slab waveguide structure disposed on the semiconductor substrate and extending from the coupling region to the region. The slab waveguide includes a confinement layer disposed between a first cladding layer and a second cladding layer. The first cladding and the second cladding each have a refractive index that is lower than a refractive index of the confinement layer. Each pixel also includes a coupling structure disposed in the coupling region and within the slab waveguide. The coupling structure includes two materials having different indices of refraction arranged as a grating defined by a grating period. The junction region comprises a p-n junction in communication with electrical contacts for biasing and collection of carriers resulting from absorption of incident radiation.

公开(公告)号：US20170096456A1

公开(公告)日：2017-04-06

申请号：US15358786

申请日：2016-11-22

Applicant: STC.UNM

Inventor： Bryce Chackerian ,  David S. Peabody

IPC: C07K14/005 ,  C12N7/00 ,  A61K39/12

CPC classification number: C07K14/005 ,  A61K39/12 ,  A61K47/6901 ,  A61K2039/5258 ,  A61K2039/55566 ,  C12N7/00 ,  C12N2710/20023 ,  C12N2710/20034 ,  C12N2795/18123

Abstract: The invention provides immunotherapeutic and prophylactic bacteriophage viral-like particle (VLPs) which are useful in the treatment and prevention of human papillomavirus (HPV) infections and related disorders, including cervical cancer and persistent infections associated with HPV. Related compositions (e.g. vaccines), nucleic acid constructs, and therapeutic methods are also provided. VLPs and related compositions of the invention induce high titer antibody responses against HPV L2 and protect against HPV challenge in vivo. VLPs, VLP-containing compositions, and therapeutic methods of the invention induce an immunogenic response against HPV infection, confer immunity against HPV infection, protect against HPV infection, and reduce the likelihood of infection by HPV infection.

公开(公告)号：US09579381B2

公开(公告)日：2017-02-28

申请号：US14426543

申请日：2013-09-06

Applicant: STC.UNM

Inventor： Graham Timmins ,  Seong Won Choi

IPC: A61K31/4409 ,  A61K41/00

CPC classification number: A61K41/0052 ,  A61K31/4409

Abstract: The invention provides method of treating a subject suffering from, or at risk of developing, a Mycobacterium infection by administering to the subject a therapeutically-effective amount of isotopically labeled isoniazid and/or ethionamide, or an analog, derivative or prodrug thereof, and exposing the subject to a magnetic field.

Abstract translation: 本发明提供了通过向受试者施用治疗有效量的同位素标记的异烟肼和/或乙硫异烟胺或其类似物，衍生物或前药，以及暴露于受试者的方法，治疗患有或有发展为分枝杆菌感染风险的受试者 受到磁场的影响。

公开(公告)号：US20160314603A1

公开(公告)日：2016-10-27

申请号：US15103977

申请日：2014-12-15

Applicant: STC.UNM

Inventor： Cesar Carranza ,  Marios Stephanou Pattichis ,  Daniel Llamocca Obregon

IPC: G06T11/00 ,  G06F17/14

CPC classification number: G06T11/006 ,  G06F17/14 ,  G06F17/141 ,  G06K9/00973 ,  G06T2211/428

Abstract: A fast and a scalable approach for computing the forward and inverse DPRT that uses: (i) a parallel array of fixed-point adder trees to compute the additions, (ii) circular shift registers to remove the need for accessing external memory components, (iii) an image block-based approach to DPRT computation that can fit the proposed architecture to available resources, and (iv) fast transpositions that are computed in one or a few clock cycles that do not depend on the size of the input image.

Abstract translation: 用于计算正向和反向DPRT的快速和可扩展的方法，其使用：（i）用于计算加法的定点加法器树的并行阵列，（ii）循环移位寄存器以消除访问外部存储器组件的需要， iii）基于图像块的DPRT计算方法，其可以将所提出的架构适合于可用资源，以及（iv）在不依赖于输入图像的大小的一个或几个时钟周期内计算的快速转置。

公开(公告)号：US09435804B2

公开(公告)日：2016-09-06

申请号：US13967259

申请日：2013-08-14

Applicant: Board of Regents of the Nevada System of Higher Education, on behalf of the University of Nevada ,  STC.UNM ,  Regents of the University of Minnesota

Inventor： Thomas Kozel ,  William Murphy ,  Suzanne Brandt ,  Bruce R Blazar ,  Julie A Lovchik ,  Peter Thorkildson ,  Ann Percival ,  C. Rick Lyons

IPC: G01N33/53 ,  A61K39/07 ,  A01K39/02 ,  G01N33/569

CPC classification number: G01N33/56911 ,  A61K39/07 ,  A61K39/3955 ,  A61K2039/505 ,  A61K2039/54 ,  A61K2039/55566 ,  A61K2039/575 ,  A61K2039/6081 ,  C07K16/1278 ,  C07K16/2878 ,  C07K2317/75 ,  C07K2317/92 ,  G01N2333/32 ,  A61K2300/00

Abstract: Compositions and methods for the detection, prevention, or treatment of anthrax or other infectious diseases. In one aspect, the present invention provides methods for immunizing humans or animals against Bacillus anthracis or other capsulated pathogens. The methods include administering a capsular polypeptide of a pathogen of interest and a CD40 agonist to a human or animal. The capsular polypeptide or the CD40 agonist is administered in such an amount or frequency that an immunoprotective response can be elicited in the human or animal against the pathogen of interest. In another aspect, the present invention provides methods of using passive immunization with anti-capsular polypeptide antibodies to prevent or treat infections caused by Bacillus anthracis or other pathogens. In yet another aspect, the present invention provides methods useful for diagnosis of anthrax by detection of capsular polypeptide in serum or other biological samples.

Abstract translation: 用于检测，预防或治疗炭疽或其他传染病的组合物和方法。 一方面，本发明提供了用于免疫人或动物针对炭疽芽孢杆菌或其他包裹的病原体的方法。 所述方法包括向人或动物施用目的病原体的荚膜多肽和CD40激动剂。 荚膜多肽或CD40激动剂以可以在人或动物中针对感兴趣的病原体引起免疫保护反应的量或频率施用。 另一方面，本发明提供了使用被动免疫与抗荚膜多肽抗体来预防或治疗由炭疽芽孢杆菌或其他病原体引起的感染的方法。 另一方面，本发明提供了通过检测血清或其他生物样品中的荚膜多肽来诊断炭疽的方法。

公开(公告)号：US09430842B1

公开(公告)日：2016-08-30

申请号：US14334446

申请日：2014-07-17

Applicant: STC.UNM

Inventor： Majeed M. Hayat ,  Sanjay Krishna ,  Sebastian Eugenio Godoy

IPC: G06T7/00 ,  G06K9/62 ,  G06K9/46 ,  G06T7/40

CPC classification number: G06T7/0085 ,  G06K9/4604 ,  G06K9/4638 ,  G06K9/4652 ,  G06K9/6268 ,  G06K9/6289 ,  G06K2009/4657 ,  G06T7/13 ,  G06T2207/10036 ,  G06T2207/10048 ,  G06T2207/30184

Abstract: Apparatus, systems, and methods fusing material classification with spatio-spectral edge detection in spectral imagery can be used in a variety of applications. In various embodiments, a classifier can be applied to neighboring pixels in data for an image to determine, based on material changes, if the neighboring pixels are correlated to two different materials with respect to a candidate location for an edge. Results of the classification can be used with a spatio-spectral mask to accept or reject the candidate location as an edge. Additional apparatus, systems, and methods are disclosed.

Abstract translation: 将光谱图像中的物质分类与空间光谱边缘检测融合的装置，系统和方法可用于各种应用。 在各种实施例中，分类器可以应用于用于图像的数据中的相邻像素，以基于材料变化来确定相邻像素是否相对于边缘的候选位置与两种不同的材料相关联。 可以使用分类结果与空间光谱掩模接受或拒绝候选位置作为边缘。 公开了附加装置，系统和方法。