公开(公告)号：US08473023B2

公开(公告)日：2013-06-25

申请号：US12625470

申请日：2009-11-24

Applicant: Seth J. Worley ,  Shiva Sharareh

Inventor： Seth J. Worley ,  Shiva Sharareh

IPC: A61B5/04 ,  A61B18/14

CPC classification number: A61M25/0068 ,  A61B18/1492 ,  A61B2017/00867 ,  A61B2018/00375 ,  A61B2018/1435 ,  A61M25/003 ,  A61M25/007 ,  A61M25/0071 ,  A61M25/008 ,  A61M25/0082 ,  A61M25/0147 ,  A61M2025/004 ,  A61M2025/0161 ,  C08L2201/12

Abstract: A catheter for mapping and/or ablating continuous linear or circumferential lesions at the intersection of a generally flat structure, such as the left atrium, and the ostium of generally cavernous regions of the heart, including pulmonary vein and the pulmonary venous antrum, comprises a catheter body with an intermediate section that is connected to a tip assembly by a highly flexible section. The intermediate section has at its distal end a preformed section, e.g., a curve, the intermediate section being deflectable in a direction opposite to the curve. The highly flexible section presets the tip assembly at an off-axis and/or off-plane angles from the preformed section. Accordingly, the preformed section is adapted to sit in the region and the preset angles of the ablation assembly enable contact with surrounding tissue. A high bending modulus enables the flexible section absorb displacement force applied to the ablation assembly, such as when the tip assembly encounters uneven tissue surface, without displacing the curve from the region. The tip assembly can be irrigated as enabled by a plurality of irrigation ports, a coil electrode, and a porous covering to disperse fluid over the outer surface of the tip assembly.

公开(公告)号：US08435237B2

公开(公告)日：2013-05-07

申请号：US12356650

申请日：2009-01-21

Applicant: Timothy J. Bahney

Inventor： Timothy J. Bahney

IPC: A61B18/18 ,  A61B17/24 ,  A61B17/26

CPC classification number: A61B18/1482 ,  A61B17/221 ,  A61B17/32056 ,  A61B18/10 ,  A61B18/1492 ,  A61B2017/00269 ,  A61B2017/00287 ,  A61B2017/00353 ,  A61B2017/00867 ,  A61B2018/00601 ,  A61B2018/00642 ,  A61B2018/1407 ,  A61B2018/141 ,  A61B2018/144 ,  A61F2002/30095 ,  A61F2210/0023 ,  C08L2201/12

Abstract: An endoscopic electrosurgical instrument is presented for encapsulating and resecting biologic tissue, such as a polyp, from an anatomical structure, such as a lumen. The instrument includes an encapsulation assembly which includes a snare coupled to an electrically non-conductive, shrinkable pouch in a drawstring-like configuration. The encapsulation assembly may be folded within the elongated cylindrical housing of the endoscopic instrument, positioned within the patient at the surgical site, and deployed for use. Once positioned over the polyp, the snare is tightened around the peduncle thereof, and the pouch is activated, thereby shrinking and encapsulating the polyp. The polyp may then be resected using conventional or electrosurgical techniques. The disclosed instrument may include surgical tools and/or electrosurgical electrodes for performing surgical procedures. The disclosed system may reduce the occurrence of undesirable arcing and may aid retrieval of resected tissue.

公开(公告)号：US08389100B2

公开(公告)日：2013-03-05

申请号：US12905513

申请日：2010-10-15

Applicant: Moshe Rock ,  Veronica Hunt ,  Brian Durant ,  David Gilbert

Inventor： Moshe Rock ,  Veronica Hunt ,  Brian Durant ,  David Gilbert

IPC: D02G3/04 ,  B32B33/00

CPC classification number: D01D5/22 ,  A41D31/0033 ,  C08L2201/12 ,  D01D5/32 ,  D01F8/06 ,  D02G3/045 ,  D04B21/04 ,  D10B2321/021 ,  D10B2321/022 ,  D10B2401/046 ,  Y10T428/23957 ,  Y10T428/2929 ,  Y10T442/3065 ,  Y10T442/3089 ,  Y10T442/3122 ,  Y10T442/3976

Abstract: A textile fabric has at least one raised surface incorporating multicomponent fibers formed of at least a first polymer and a second polymer disposed in side-by-side relationship. The first polymer and the second polymer exhibit differential thermal elongation, which causes the multicomponent fibers to bend or curl and reversibly recover in response to changes in temperature, thereby adjusting insulation performance of the textile fabric in response to ambient conditions.

Abstract translation: 纺织品织物具有至少一个凸起表面，该凸起表面包含由至少第一聚合物和以并排关系设置的第二聚合物形成的多组分纤维。 第一聚合物和第二聚合物表现出不同的热延伸率，这导致多组分纤维响应于温度变化而弯曲或卷曲并且可逆地恢复，由此响应于环境条件调节纺织织物的绝缘性能。

公开(公告)号：US08365833B2

公开(公告)日：2013-02-05

申请号：US12732617

申请日：2010-03-26

Applicant: Nicholas Carrejo ,  Michael H. Johnson

Inventor： Nicholas Carrejo ,  Michael H. Johnson

IPC: E21B23/00

CPC classification number: E21B41/00 ,  C08L2201/12 ,  C09K3/1021 ,  E21B43/08 ,  E21B43/108 ,  F03G7/065 ,  Y10T29/49865 ,  Y10T156/1005

Abstract: Wellbore devices for use in filtration, wellbore isolation, production control, lifecycle management and wellbore construction may include at least a first and a second shape-memory material each having a an altered geometric position and each an original geometric position. Each shape-memory material may include a polyurethane material held in the altered geometric run-in position at a temperature below glass transition temperature (Tg), where the Tgs and/or the respective slope changes of the first and second polyurethane materials are different. Once the wellbore device is in place downhole and the first and second shape-memory materials are subjected to temperatures above their Tgs, the materials will deploy and expand to recovered geometric positions at or near their original geometric positions to perform their filtration, isolation, control or other function. These deployments or expansions may occur at different times or rates.

Abstract translation: 用于过滤，井眼隔离，生产控制，生命周期管理和井眼结构的井筒装置可以包括至少第一和第二形状记忆材料，每个具有改变的几何位置和每个原始几何位置。 每种形状记忆材料可以包括在低于玻璃化转变温度（Tg）的温度下保持在改变的几何入口位置的聚氨酯材料，其中第一和第二聚氨酯材料的Tg和/或相应的斜率变化是不同的。 一旦井眼装置在井下就位，并且第一和第二形状记忆材料经受高于其Tg的温度，则材料将在其原始几何位置处或附近展开并扩展至恢复的几何位置，以执行其过滤，隔离，控制 或其他功能。 这些部署或扩展可能会发生在不同的时间或速度。

公开(公告)号：US08357153B2

公开(公告)日：2013-01-22

申请号：US12522721

申请日：2008-01-11

Applicant: Nagy Habib

Inventor： Nagy Habib

IPC: A61B18/14

CPC classification number: A61B18/082 ,  A61B18/1492 ,  A61B2017/00867 ,  A61B2018/00214 ,  A61B2018/00267 ,  A61B2018/1435 ,  A61B2018/1467 ,  A61B2018/1495 ,  C08L2201/12

Abstract: Devices suitable for insertion into a hollow anatomical structure within a patient for the purpose of ablating tissue within or surrounding the hollow structure so as to induce occlusion of the hollow structure are provided. The devices are in the form of guidewires with functional tips, that comprise at least one heating module, at their distal ends. The devices of the invention are suitable for occluding hollow anatomical structures selected from vasculature or from non-vascular ducts and tubes, via percutaneous, laparoscopic or endoscopic routes of access. Methods of using the devices in the treatment of patients are also described.

Abstract translation: 提供了适于插入到患者体内的中空解剖结构中的装置，用于在中空结构内或周围消融组织以引起中空结构的闭塞。 这些装置是具有功能尖端的导线的形式，其在其远端包括至少一个加热模块。 本发明的装置适合于通过经皮，腹腔镜或内窥镜进入途径闭塞从脉管系统或非血管导管和管中选择的中空解剖结构。 还描述了在患者治疗中使用该装置的方法。

公开(公告)号：US20130018111A1

公开(公告)日：2013-01-17

申请号：US13635797

申请日：2011-03-18

Applicant: Xian Jun Loh ,  Jun Li

Inventor： Xian Jun Loh ,  Jun Li

IPC: C08G81/00 ,  A61K47/34

CPC classification number: C08G81/00 ,  A61K47/34 ,  A61L27/14 ,  A61L27/50 ,  A61L27/58 ,  A61L29/04 ,  A61L29/14 ,  A61L29/148 ,  A61L31/04 ,  A61L31/14 ,  A61L31/148 ,  A61L2400/16 ,  B29C61/003 ,  C08G18/4277 ,  C08G18/61 ,  C08G18/73 ,  C08G63/08 ,  C08G63/664 ,  C08G77/16 ,  C08G77/458 ,  C08G2230/00 ,  C08G2261/126 ,  C08G2280/00 ,  C08K5/57 ,  C08L87/005 ,  C08L2201/12 ,  C09D187/005

Abstract: This invention relates to shape memory block copolymers comprising: at least one switching segment having a Ttrans from 10 to 70° C.; and at least one soft segment, wherein at least one of the switching segments is linked to at least one of the soft segments by at least one linkage, and wherein the copolymer transforms from a first shape to a second shape by application of a first stimulus and the copolymer transforms back to the first shape from the second shape by application of a second stimulus. The shape memory block copolymers may be biocompatible and biodegradable.

Abstract translation: 本发明涉及形状记忆嵌段共聚物，其包含：至少一个具有10-70℃的Ttrans的切换区段; 和至少一个软链段，其中所述切换段中的至少一个通过至少一个键连接到所述软链段中的至少一个，并且其中所述共聚物通过施加第一刺激从第一形状转变为第二形状 并且共聚物通过施加第二刺激从第二形状转变回第一形状。 形状记忆嵌段共聚物可以是生物相容的和可生物降解的。

公开(公告)号：US20120215305A1

公开(公告)日：2012-08-23

申请号：US13397945

申请日：2012-02-16

Applicant: Le Le ,  Jason Tran ,  Jesus Flores ,  Kelly Mac

Inventor： Le Le ,  Jason Tran ,  Jesus Flores ,  Kelly Mac

IPC: A61F2/24

CPC classification number: A61F2/2448 ,  A61B18/1492 ,  A61B18/18 ,  A61B18/20 ,  A61B2017/00867 ,  A61B2018/00821 ,  A61B2218/002 ,  A61F2/2445 ,  A61F2210/0038 ,  A61F2250/0001 ,  A61F2250/0004 ,  C08L2201/12

Abstract: An adjustable implantable medical device and adjustment device are described. In some embodiments, the adjustment device includes a lead with a distal end modified to permit better engagement and securement to the described implantable devices. In some embodiments, the contact of the lead is bent. Some embodiments include a coil that engages and secures the lead to the implantable device. Some embodiments include a suture line to aid in securing the lead to the implantable device.

Abstract translation: 描述了一种可调式可植入医疗装置和调节装置。 在一些实施例中，调节装置包括具有被修改以允许更好地接合和固定到所描述的可植入装置的远端的引线。 在一些实施例中，引线的接触是弯曲的。 一些实施例包括将引线接合并固定到可植入装置的线圈。 一些实施例包括有助于将引线固定到可植入装置的缝合线。

公开(公告)号：US20120211413A1

公开(公告)日：2012-08-23

申请号：US13029729

申请日：2011-02-17

Applicant: Randall V. Guest ,  Michael H. Johnson ,  Kirk J. Huber

Inventor： Randall V. Guest ,  Michael H. Johnson ,  Kirk J. Huber

IPC: B01D35/00 ,  C08K3/38 ,  B29C43/00 ,  C08K3/34 ,  C08L77/10 ,  B29C71/00 ,  C08L61/16 ,  C08K3/08

CPC classification number: B01D29/0093 ,  B01D29/111 ,  B29C43/003 ,  B29C61/0608 ,  B29L2031/14 ,  C08K3/08 ,  C08K3/34 ,  C08K3/38 ,  C08L77/10 ,  C08L2201/12

Abstract: A shape memory structure includes, an elastic material, and a viscoelastic material commingled with the elastic material. The shape memory structure is reformable from a first shape to a second shape upon exposure to a change in environment that softens the viscoelastic material thereby allowing the shape memory structure to creep under stress stored in the elastic material.

Abstract translation: 形状记忆结构包括弹性材料和与弹性材料混合的粘弹性材料。 形状记忆结构在暴露于软化环境的环境变化时可从第一形状重新形成为第二形状，从而允许形状记忆结构在存储在弹性材料中的应力下蠕变。

公开(公告)号：US20120204387A1

公开(公告)日：2012-08-16

申请号：US13453630

申请日：2012-04-23

Applicant: James M. Carlson ,  Shyam S.V. Kuppurathanam ,  Fred T. Parker ,  Rebecca Sue Todd

Inventor： James M. Carlson ,  Shyam S.V. Kuppurathanam ,  Fred T. Parker ,  Rebecca Sue Todd

IPC: D06C7/00 ,  D03D41/00

CPC classification number: A61F2/90 ,  A61F2/06 ,  A61F2/07 ,  A61F2002/075 ,  A61F2210/0014 ,  A61L31/022 ,  A61L31/041 ,  A61L31/14 ,  A61L2400/16 ,  C08L2201/12 ,  D02G3/12 ,  D02G3/448 ,  D03D3/02 ,  D03D13/004 ,  D03D13/008 ,  D03D15/00 ,  D03D15/08 ,  D10B2101/20 ,  D10B2321/021 ,  D10B2321/022 ,  D10B2321/042 ,  D10B2331/04 ,  D10B2331/10 ,  D10B2401/046 ,  D10B2401/061 ,  D10B2509/06

Abstract: The disclosure relates to a woven fabric for use in an implantable medical device. The woven fabric comprises shape memory element strands woven with textile strands. At least one of the shape memory element strands has at least one float of at least five textile strands between binding points.

Abstract translation: 本公开涉及用于可植入医疗装置的机织织物。 机织织物包括用织物股线编织的形状记忆元件股。 形状记忆元件股线中的至少一个在结合点之间具有至少一个至少五个纺织股线的浮子。

公开(公告)号：US20120203160A1

公开(公告)日：2012-08-09

申请号：US13501599

申请日：2010-10-12

Applicant: Malik Y. Kahook ,  Naresh Mandava ,  Robin Shandas ,  Bryan Rech

Inventor： Malik Y. Kahook ,  Naresh Mandava ,  Robin Shandas ,  Bryan Rech

IPC: A61F9/007

CPC classification number: A61F9/00781 ,  A61K9/0051 ,  A61L2400/16 ,  A61L2430/16 ,  C08L2201/12

Abstract: The present invention provides ocular implants adapted to reside in Schlemm's canal for reducing intraocular pressure of an eye and methods for using the same. In some embodiments the ocular implants comprise a thin rod adapted and configured to extend in a curved volume in Schlemm's canal. The thin rod comprises a plurality of wave-shaped segments such that a sufficient number and amount of wave-shaped segments extend to the inner wall of the trabecular meshwork and to the outer wall of Schlemm's canal thereby keeping Schlemm's canal open.

Abstract translation: 本发明提供适于驻留在施莱姆氏管中以减少眼睛眼内压的眼部植入物及其使用方法。 在一些实施例中，眼部植入物包括适于和构造成在Schlemm管中以弯曲体积延伸的细杆。 细杆包括多个波形段，使得足够数量的波形段延伸到小梁网的内壁和Schlemm管的外壁，从而保持施莱姆管的开放。