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    NANO-ELECTRO-MECHANICAL LABELS AND ENCODER
    181.
    发明申请
    NANO-ELECTRO-MECHANICAL LABELS AND ENCODER 审中-公开

    公开(公告)号：US20190188546A1

    公开(公告)日：2019-06-20

    申请号：US16011509

    申请日：2018-06-18

    Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.

    Inventor： Roozbeh Tabrizian ,  Swarup Bhunia

    IPC: G06K19/04 ,  G06K1/12 ,  H01L41/09 ,  H01L41/314 ,  H01L41/187

    Abstract: Data is encoded for identification and labeling using a multitude of nano-electro-mechanical structures formed on a substrate. The number of such structures, their shapes, choice of materials, the spacing therebetween and the overall distribution of the structures result in a vibrational pattern or an acoustic signature that uniquely corresponds to the encoded data. A first group of the structures is formed in conformity with the design rules of a fabrication process used to manufacture the device that includes the structures. A second group of the structures is formed so as not to conform to the design rules and thereby to undergo variability as a result of the statistical variations that is inherent in the fabrication process.

    LOW COST DISPOSABLE MEDICAL SENSOR FABRICATED ON GLASS, PAPER OR PLASTICS
    183.
    发明申请
    LOW COST DISPOSABLE MEDICAL SENSOR FABRICATED ON GLASS, PAPER OR PLASTICS 审中-公开

    公开(公告)号：US20190170738A1

    公开(公告)日：2019-06-06

    申请号：US16206493

    申请日：2018-11-30

    Applicant: University of Florida Research Foundation, Inc.

    Inventor： Fan Ren ,  Stephen J. Pearton

    IPC: G01N33/543 ,  G01N33/68 ,  H01L29/20 ,  H01L29/778

    Abstract: Various examples are provided for low cost disposable medical sensors fabricated on glass, paper or plastics, and applications thereof. In one example, a medical sensor includes a base structure comprising a functionalized sensing area; and a transistor disposed on the base structure adjacent to the functionalized sensing area. In another example, a medical sensor includes a base structure comprising a functionalized sensing area disposed on a first electrode pad and a reference sensing area disposed on a second electrode pad separated from the first electrode pad; and a transistor having a gate electrically coupled to the second electrode pad of the base structure. A gate pulse applied to the functionalized sensing can produce a drain current corresponding to an amount of a target present in a sample disposed on the base structure.

    rAAV vectors and methods for transduction of photoreceptors and RPE cells
    184.
    发明授权
    rAAV vectors and methods for transduction of photoreceptors and RPE cells 有权

    公开(公告)号：US10308957B2

    公开(公告)日：2019-06-04

    申请号：US15123515

    申请日：2015-03-04

    Applicant: University of Florida Research Foundation, Inc.

    Inventor： Shannon E. Boye ,  Sanford L. Boye ,  Mavis Agbandje-McKenna ,  Arun Srivastava

    IPC: C12N15/86 ,  C07K14/005 ,  A61K48/00 ,  A61K9/00 ,  A61K9/51

    Abstract: Disclosed are capsid-modified rAAV particles and expression vectors, as well as compositions and pharmaceutical formulations that comprise them. Also disclosed are methods of preparing and using novel capsid-protein-mutated particle or rAAV vector constructs in a variety of diagnostic and therapeutic applications including, inter alia, as delivery agents for diagnosis, treatment, or amelioration of one or more diseases, disorders, or dysfunctions of the mammalian eye. Also disclosed are methods for subretinal delivery of therapeutic gene constructs to mammalian photoreceptors and retinal pigment epithelial cells, as well as use of the disclosed compositions in the manufacture of medicaments for a variety of in vitro and/or in vivo applications including the treatment of a variety of inherited retinal diseases.

    TEXTURIZED INSECTICIDAL FORMULATION
    187.
    发明申请
    TEXTURIZED INSECTICIDAL FORMULATION 审中-公开

    公开(公告)号：US20190142003A1

    公开(公告)日：2019-05-16

    申请号：US16097934

    申请日：2017-05-25

    Applicant: Philip G. KOEHLER ,  Roberto M. PERERIA ,  Christopher D. BATICH ,  University of Florida Research Foundation, Inc.

    Inventor： Philip G. Koehler ,  Roberto M. Pereira ,  Christopher D. Batich

    IPC: A01N43/40 ,  A01N53/00

    Abstract: Compositions, formulas, methods of making, mixing and applying insecticide formulations to different surfaces such as but not limited to interior surfaces of ovitraps, on walls and on chips and tiles to produce a texturized surface to allow for better transfer of the insecticidal active ingredients to insects, such as mosquitoes and the like, which land on or crawl on the surfaces, resulting in faster insect mortality rates. The texture of the insecticidal residue provides better transfer of the insecticidal active ingredients to insects that land on or crawl on the surface, resulting in faster insect mortality. The textured residue also enhances desirable surface characteristics for landing of mosquitoes and potentially other insects.

    Methods and compositions for terpenoid tricycloalkane synthesis
    188.
    发明授权
    Methods and compositions for terpenoid tricycloalkane synthesis 有权

    公开(公告)号：US10287239B1

    公开(公告)日：2019-05-14

    申请号：US15981833

    申请日：2018-05-16

    Applicant: University of Florida Research Foundation, Inc.

    Inventor： Alexander James Grenning ,  Sarah Scott

    IPC: C07C253/30 ,  C07C255/31 ,  C07C255/47 ,  C07D227/04

    Abstract: In one aspect, the disclosure relates to methods for preparation of intermediates useful for the preparation of terpenoid cores. In a further aspect, the disclosed methods pertain to the preparation of compounds comprising a terpenoid core or scaffold, such as 6/7/5 tricycloalkanes. The disclosed methods utilize abundant starting materials and simple reaction sequences that can be used to tunably and scalably assemble common terpenoid cores. In various aspects, the present disclosure pertains to compounds prepared using the disclosed methods. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present disclosure.

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