公开(公告)号：US09956262B2

公开(公告)日：2018-05-01

申请号：US14893366

申请日：2014-05-23

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) ,  UNIVERSITE DE RENNES 1 ,  UNIVERSITE DE BRETAGNE OCCIDENTALE

Inventor： Florie Desriac ,  Yannick Fleury ,  Patrick Le Chevalier ,  Delphine Destoumieux ,  Matthieu Simon

IPC: A61K35/741 ,  A61K38/12 ,  C07K7/56 ,  C11D3/28 ,  C11D3/32 ,  C11D3/38 ,  C11D3/48 ,  C12R1/01 ,  A23K10/18 ,  A23K20/195 ,  A23K50/80 ,  A61K35/74 ,  C07K7/64 ,  A61K38/00 ,  A61K35/00

CPC classification number: A61K38/12 ,  A23K10/18 ,  A23K20/195 ,  A23K50/80 ,  A61K35/74 ,  A61K35/741 ,  A61K38/00 ,  A61K2035/11 ,  C07K7/56 ,  C07K7/64 ,  C11D3/28 ,  C11D3/32 ,  C11D3/381 ,  C11D3/48 ,  C12R1/01 ,  Y02A40/818

Abstract: The present invention relates to an isolated bacterium from the genus Pseudoalteromonas for its use as a probiotic, the use of said strain as a preservative, cyclolipopeptides which may be obtained from this bacterium, a composition comprising at least such a cyclolipopeptide, as well as to their uses.

公开(公告)号：US20180112165A1

公开(公告)日：2018-04-26

申请号：US15559947

申请日：2016-03-18

Applicant: Inria Institut National De Recherche En Informatique Et En Automatique ,  Centre De La Recherche Scientifique (C.N.R.S.) ,  Universite Pierre Et Marie Curie (Paris 6)

Inventor： Francis MAIRET ,  Olivier BERNARD ,  Antoine SCIANDRA ,  Eric PRUVOST ,  Charlotte COMBE

IPC: C12M1/00

Abstract: The invention relates to a bioreactor comprising a tank containing a culture medium in which a cell culture composed of algae cells is dispersed. The cell culture of algae has a concentration greater than 0.1 g/L in the culture medium, and each algal cell has a minimum absorption in a specific range of wavelengths of light. The bioreactor comprises a light source that is capable of emitting incident light in the direction of the tank, 60% of the photons of the incident light having a wavelength which is included in said specific range of wavelengths of light. The invention also relates to the use of the bioreactor for the production of biomass.

公开(公告)号：US09938545B2

公开(公告)日：2018-04-10

申请号：US14906056

申请日：2014-07-21

Applicant: FERMENTALG ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) ,  COMMISARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES

Inventor： Pierre Calleja ,  Marina Leterrier ,  Eric Marechal

IPC: C12P7/64 ,  C12N1/12 ,  C12N15/82 ,  C12N15/74 ,  C12P19/34 ,  C12N9/14 ,  C12N9/10

CPC classification number: C12P7/6463 ,  C12N1/12 ,  C12N9/1029 ,  C12N9/14 ,  C12N15/82 ,  C12Y203/01051

Abstract: The present invention relates to a genetically engineered algae strain in which the expression of the CGI-58 gene or homologous gene thereof is silenced. The present invention further relates to a method of triacylglycerol accumulation using said genetically engineered diatom and/or diatom strain.

公开(公告)号：US09896461B2

公开(公告)日：2018-02-20

申请号：US14412888

申请日：2013-07-08

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) ,  ECOLE NATIONALE SUPERIEURE DE CHIMIE DE MONTPELLIER ,  UNIVERSITE MONTPELLIER 2, SCIENCES ET TECHNIQUES

Inventor： Michel Wong Chi Man ,  Xavier Cattoën ,  Kristyna Bürglova ,  Jana Hodacova

IPC: C07F7/18 ,  C07F9/40 ,  C07F9/6518

CPC classification number: C07F7/1804 ,  C07F9/4006 ,  C07F9/6518

Abstract: The invention concerns a mono- or polyfunctional polysilylated organosilane compound, and the method for preparing same.

公开(公告)号：US20170351080A1

公开(公告)日：2017-12-07

申请号：US15539457

申请日：2015-12-23

Applicant: Commissariat à l'énergie atomique et aux énergies alternatives ,  Centre national de la recherche scientifique (C.N.R.S)

Inventor： Bruno ROBERT ,  Andrew GALL ,  Dmitrij FROLOV ,  Rienk VAN GRONDELLE

IPC: G02B21/36 ,  G02B21/00

CPC classification number: G02B21/365 ,  G02B21/0036 ,  G02B21/0072 ,  G02B21/0076 ,  G02B21/008 ,  G02B21/367

Abstract: Method for obtaining an super-resolution image (22) of an object (5), based upon an optical microscope (21) including a support plate (6) for bearing the object, an illumination source (1) for focusing an illumination beam (14) onto a target region of the support plate, a digital camera (9) including a matrix of sensors, comprising: capturing, by the digital camera, a first image of the target region; extracting, from the first image, a first block of pixel values provided by a sub-matrix (B0) of the matrix of sensors; displacing, by a sub-diffraction limited distance, the support plate by the displacement block along a displacement axis; capturing, by the digital camera, a second image of the target region; extracting, from the second image, a second block of pixel values provided by the sub-matrix (B0) of the matrix of sensors; storing said first and second blocks of pixel values as a first and second blocks of pixel values to be placed right next each other in the super-resolution image along the image axis (X, Y) corresponding to the displacement axis.

公开(公告)号：US20170121298A1

公开(公告)日：2017-05-04

申请号：US15318662

申请日：2015-06-11

Applicant: SYRAL BELGIUM NV ,  UNIVERSITÉ CLAUDE BERNARD LYON 1 ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)

Inventor： Charlotte GOZLAN ,  Nicolas DUGUET ,  Marc LEMAIRE ,  Andreas REDL

IPC: C07D307/20 ,  C11D1/66 ,  C10M129/20

CPC classification number: C07D307/20 ,  A61K8/4973 ,  A61Q19/00 ,  B01F17/0021 ,  C07C43/10 ,  C07H3/10 ,  C07H15/04 ,  C10M129/20 ,  C10M2207/044 ,  C11D1/662

Abstract: A composition of monoanhydro-hexitol monoalkyl ether isomers bearing an alkyl ether radical (OR) at C-3, C-5 or C-6 of the monoanhydro-hexitol, in which the alkyl group (R) is a linear or branched, cyclic or noncyclic hydrocarbon-based group comprising between 4 to 18 carbon atoms, the process for obtaining such a composition and the use thereof as a nonionic surfactant, emulsifier, lubricant, antimicrobial agent or dispersant.

公开(公告)号：US20170029768A1

公开(公告)日：2017-02-02

申请号：US15106714

申请日：2014-12-19

Applicant: KALLISTEM ,  UNIVERSITÉ CLAUDE BERNARD LYON 1 ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) ,  INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE (INRA) ,  ECOLE NORMALE SUPERIEURE DE LYON

Inventor： Marie-Hélène PERRARD ,  Philippe DURAND ,  Laurent DAVID

IPC: C12N5/076 ,  C12N5/075

CPC classification number: C12N5/061 ,  C12N5/0609 ,  C12N2500/05 ,  C12N2500/25 ,  C12N2500/38 ,  C12N2501/31 ,  C12N2501/385 ,  C12N2501/392 ,  C12N2533/72

Abstract: The present invention relates to a process for in vitro spermatogenesis from male germinal tissue comprising conducting maturation of testicular tissue comprising germ cells in a bioreactor which is made of a biomaterial and comprises at least one cavity wherein the germinal tissue is placed, and recovering elongated spermatids and/or spermatozoa.

Abstract translation: 本发明涉及一种用于从雄性生发组织进行体外精子发生的方法，包括在由生物材料制成的生物反应器中包含生殖细胞的睾丸组织的导入成熟并且包括至少一个其中放置生发组织的空腔，并且恢复细长的精子细胞 和/或精子。

公开(公告)号：US20160376300A1

公开(公告)日：2016-12-29

申请号：US15039796

申请日：2014-11-26

Applicant: INSTITUT POLYTECHNIQUE DE BORDEAUX ,  UNIVERSITÉ DE BORDEAUX ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S)

Inventor： Stéphane GRELIER ,  GEORGES KOUMBA YOYA

IPC: C07G1/00 ,  C12P7/22 ,  C12N9/02

CPC classification number: C07G1/00 ,  C12N9/0061 ,  C12P7/22 ,  C12P7/40 ,  C12Y110/03002

Abstract: A method for depolymerization of lignin includes oxidizing non-phenolic lignin by putting into presence, in at least one solvent, non-phenolic lignin, laccase, redox mediator and a source of oxygen, whereby a mixture including oxidized non-phenolic lignin is obtained, and further includes depolymerization of the oxidized non-phenolic lignin thereby obtained, by adding an oxidizer. The non-phenolic lignin is obtained from phenolic lignin by functionalization of phenol functions of the phenolic lignin.

Abstract translation: 一种木质素解聚方法包括通过在至少一种溶剂，非酚类木质素，漆酶，氧化还原介体和氧源中放置氧化非酚类木质素，由此获得包含氧化的非酚性木质素的混合物， 并且还包括通过添加氧化剂使由此获得的氧化的非酚性木质素解聚。 非酚类木质素通过官能化酚类木质素的酚官能团从酚类木质素获得。

公开(公告)号：US09499559B2

公开(公告)日：2016-11-22

申请号：US14898475

申请日：2014-06-13

Applicant: SYRAL BELGIUM NV ,  UNIVERSITÉ CLAUDE BERNARD LYON 1 ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)

Inventor： Charlotte Gozlan ,  Nicolas Duguet ,  Marc Lemaire ,  Yves Queneau ,  Andreas Redl

IPC: C07D493/04 ,  C07D407/04

CPC classification number: C07D493/04 ,  C07D407/04

Abstract: Long-chain alkyl cyclic acetals made from sugars are obtainable by a method that comprises the steps consisting of: dehydrating a hexitol in a monoanhydrohexitol substrate; reacting the monoanhydrohexitol substrate obtained with an alkyl aldehyde reagent containing 5 to 18 carbon atoms, by means of an acetalization reaction with a substrate/reagent ratio of between 5:1 and 1:1, or with a derivative of an alkyl aldehyde reagent containing 5 to 18 carbon atoms, by means of a transacetalization reaction with a substrate/reagent ratio of between 1:1 and 1:3, in the presence of acid catalyst and in an environment that is free of solvent or that consists of non-aqueous polar solvent; collecting the long-chain alkyl acetal of hexitan from the mixture obtained.

公开(公告)号：US09464025B2

公开(公告)日：2016-10-11

申请号：US14410905

申请日：2013-06-28

Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S) ,  UNIVERSITE CLAUDE BERNARD LYON 1

Inventor： Nadine Essayem ,  Gilbert Sapaly ,  Marion Eternot ,  Franck Rataboul

IPC: C07C67/00 ,  C10L1/16 ,  C10L1/19

CPC classification number: C07C67/00 ,  C10L1/1608 ,  C10L1/19 ,  C10L2200/0469 ,  C10L2270/023 ,  C10L2270/026 ,  Y02P20/544 ,  C07C69/716

Abstract: A method for preparing at least one ester of levulinic acid from a biomass includes steps of impregnating the biomass by an organic or inorganic acid, and putting the acidified biomass in contact with a supercritical fluid including at least one olefin.

Abstract translation: 从生物质制备乙酰丙酸的至少一种酯的方法包括以下步骤：通过有机或无机酸浸渍生物质，并将酸化的生物质与包含至少一种烯烃的超临界流体接触。