公开(公告)号：US09034346B2

公开(公告)日：2015-05-19

申请号：US13357033

申请日：2012-01-24

Applicant: Kathleen M. Miller ,  Gregory T. Sydney ,  Kurt Geitz ,  Peter L. Dayton ,  Ronald A. Sahatjian

Inventor： Kathleen M. Miller ,  Gregory T. Sydney ,  Kurt Geitz ,  Peter L. Dayton ,  Ronald A. Sahatjian

IPC: A61L2/232 ,  A61L29/16 ,  A61L31/16

CPC classification number: A61L2/232 ,  A61L29/16 ,  A61L31/16 ,  A61L2300/202 ,  A61L2300/206 ,  A61L2300/21 ,  A61L2300/404 ,  A61L2300/45 ,  Y10T428/1334 ,  Y10T428/1352 ,  Y10T428/1372 ,  Y10T428/1379 ,  Y10T428/1386 ,  Y10T428/1393

Abstract: Disclosed are implantable or insertable medical devices that provide resistance to microbial growth on and in the environment of the device and resistance to microbial adhesion and biofilm formation on the device. In particular, the invention discloses implantable or insertable medical devices that comprise at least one biocompatible matrix polymer region, an antimicrobial agent for providing resistance to microbial growth and a microbial adhesion/biofilm synthesis inhibitor for inhibiting the attachment of microbes and the synthesis and accumulation of biofilm on the surface of the medical device. Also disclosed are methods of manufacturing such devices under conditions that substantially prevent preferential partitioning of any of said bioactive agents to a surface of the biocompatible matrix polymer and substantially prevent chemical modification of said bioactive agents.

Abstract translation: 公开了可植入或可插入的医疗装置，其在装置的环境和环境中提供对微生物生长的抵抗力，并且抵抗微生物附着和在装置上的生物膜形成。 特别地，本发明公开了可植入或可插入的医疗装置，其包括至少一个生物相容性基质聚合物区域，用于提供对微生物生长的抗性的抗微生物剂和用于抑制微生物附着的微生物粘附/生物膜合成抑制剂以及合成和积累 生物膜在医疗器械的表面上。 还公开了在基本上防止任何所述生物活性剂优先分配到生物相容性基质聚合物的表面并基本上防止所述生物活性剂的化学修饰的条件下制造这种装置的方法。

公开(公告)号：US20090281374A1

公开(公告)日：2009-11-12

申请号：US12352179

申请日：2009-01-12

Applicant: Gary Leanna ,  Kurt Geitz ,  Oscar R. Carrillo, JR. ,  Kevin Richardson

Inventor： Gary Leanna ,  Kurt Geitz ,  Oscar R. Carrillo, JR. ,  Kevin Richardson

IPC: A61B1/00

CPC classification number: A61B1/00149 ,  A61B1/00006 ,  A61B1/00018 ,  A61B1/00082 ,  A61B1/00087 ,  A61B1/00094 ,  A61B1/00096 ,  A61B1/00147 ,  A61B1/005 ,  A61B1/273 ,  A61B17/00234 ,  A61B2017/00778 ,  A61B2017/00986 ,  A61B2017/3488

Abstract: A device for accessing tissue within a body lumen comprises an elongated body portion defining a lumen and an anchoring mechanism including an expanding structure on a distal portion of the elongated body portion. The anchoring mechanism moves the expanding structure from an insertion configuration in which the expanding structure is constricted against the device to an operative configuration in a body in which the expanding structure expands away from the device without altering a length of the anchoring mechanism in combination with a control mechanism for selectively engaging the anchoring mechanism.

Abstract translation: 用于访问体腔内的组织的装置包括限定内腔的细长主体部分和包括在细长主体部分的远侧部分上的扩张结构的锚定机构。 锚固机构将膨胀结构从其中膨胀结构收缩的插入构型移动到主体中的可操作构造，其中，膨胀结构从该装置远离该装置而不改变锚定机构的长度与一个 用于选择性地接合锚定机构的控制机构。

公开(公告)号：US20080312751A1

公开(公告)日：2008-12-18

申请号：US12216789

申请日：2008-07-10

Applicant: Charles H. Pugsley ,  Marcia McBride-Sakal ,  Kurt Geitz

Inventor： Charles H. Pugsley ,  Marcia McBride-Sakal ,  Kurt Geitz

IPC: A61F2/02 ,  A61B17/08

CPC classification number: A61F13/00063 ,  A61F13/0213 ,  A61F13/0226 ,  A61F13/0253 ,  A61L15/40 ,  A61L15/64

Abstract: Endoluminally delivered tissue patches and related systems and methods for delivering the tissue patches for treating lesions of the alimentary tract are disclosed. A tissue patch includes a substrate, a tissue implant attached to the substrate, and a protective liner covering at least a portion of the tissue implant. A method includes providing a tissue patch having a tissue implant attached to a substrate and a protective liner covering at least a portion of the tissue implant. The tissue patch is formed into a contracted state and inserted into a lumen containing the lesion. The tissue patch then is positioned in the vicinity of the lesion. After removing the protective liner to reveal the tissue implant, the tissue implant is placed in the lesion.

Abstract translation: 公开了用于递送用于治疗消化道病变的组织贴片的内给药组织贴片和相关系统和方法。 组织贴片包括衬底，附着到衬底的组织植入物和覆盖组织植入物的至少一部分的保护衬垫。 一种方法包括提供具有附着到基底的组织植入物和覆盖组织植入物的至少一部分的保护性衬里的组织贴片。 组织贴片形成收缩状态并插入含有病变的内腔。 然后将组织贴片定位在病变附近。 在去除保护衬垫以露出组织植入物之后，将组织植入物放置在病变体内。

公开(公告)号：US20080188890A1

公开(公告)日：2008-08-07

申请号：US11946790

申请日：2007-11-28

Applicant: Barry Weitzner ,  Paul J. Smith ,  Kurt Geitz

Inventor： Barry Weitzner ,  Paul J. Smith ,  Kurt Geitz

IPC: A61B17/00

CPC classification number: A61B34/74 ,  A61B1/00039 ,  A61B1/00087 ,  A61B1/0014 ,  A61B1/00147 ,  A61B1/00154 ,  A61B1/00165 ,  A61B1/00183 ,  A61B1/0052 ,  A61B1/0057 ,  A61B1/018 ,  A61B1/04 ,  A61B1/12 ,  A61B1/3132 ,  A61B10/06 ,  A61B17/00234 ,  A61B17/0218 ,  A61B17/0469 ,  A61B17/29 ,  A61B17/320016 ,  A61B34/10 ,  A61B34/70 ,  A61B34/71 ,  A61B90/11 ,  A61B2017/00212 ,  A61B2017/00287 ,  A61B2017/003 ,  A61B2017/00323 ,  A61B2017/00331 ,  A61B2017/0034 ,  A61B2017/00353 ,  A61B2017/00362 ,  A61B2017/00398 ,  A61B2017/00469 ,  A61B2017/00973 ,  A61B2017/0225 ,  A61B2017/2905 ,  A61B2017/2906 ,  A61B2017/3445 ,  A61B2017/3447 ,  A61B2090/0811 ,  A61B2090/374

Abstract: Described herein are multi-part instrument systems and methods of use. The instrument can include an inner and outer body member where the inner body member is adapted to dock with the outer body member. When docked, driving the outer body member via a manipulation section can control the inner body. In use, an inner body member can be removed and replaced by a different inner body member to change the tool end effector. Alternatively, driving a manipulation section of the inner body member can control the outer body member. The outer body member can be disposable while the inner body member is reusable.

Abstract translation: 这里描述的是多部分仪器系统和使用方法。 仪器可以包括内部和外部本体构件，其中内部主体构件适于与外部本体构件对接。 当对接时，通过操纵部驱动外身构件可以控制内体。 在使用中，可以移除内部主体构件并由不同的内部主体构件替换以改变工具端部执行器。 或者，驱动内主体部件的操作部可以控制外主体部件。 外部本体构件可以是一次性的，而内部主体构件是可重复使用的。

公开(公告)号：US20070270941A1

公开(公告)日：2007-11-22

申请号：US11436067

申请日：2006-05-17

Applicant: F. Anthony Headley ,  Kurt Geitz

Inventor： F. Anthony Headley ,  Kurt Geitz

IPC: A61F2/06

CPC classification number: A61F2/90 ,  A61F2210/0004 ,  A61L31/022 ,  A61L31/06 ,  A61L31/148 ,  A61L31/16 ,  C08L67/04

Abstract: According to an aspect of the present invention, a stent is provided, which contains at least one filament that has a longitudinal axis and comprises a bioabsorbable polymeric material. Polymer molecules within the bioabsorbable polymeric material are provided with a helical orientation which is aligned with respect to the longitudinal axis of the filament. The stent is at least partially bioabsorbed by a patient upon implantation or insertion of the stent into the patient.

Abstract translation: 根据本发明的一个方面，提供了一种支架，其包含至少一根具有纵轴并且包含生物可吸收聚合材料的细丝。 生物可吸收聚合物材料内的聚合物分子被提供有相对于长丝的纵向轴线对齐的螺旋取向。 在将支架植入或插入患者体内时，支架至少部分地被患者生物吸收。

公开(公告)号：US20070197871A1

公开(公告)日：2007-08-23

申请号：US11359897

申请日：2006-02-21

Applicant: Kurt Geitz ,  Brian Tinkham

Inventor： Kurt Geitz ,  Brian Tinkham

IPC: A61B1/00

CPC classification number: A61B1/0057 ,  A61B1/00066 ,  A61B1/00098 ,  A61B1/00133 ,  A61B1/0052 ,  A61B1/018

Abstract: Embodiments of the invention include a medical device for accessing a patient's body portion and used for diagnosis and treatment of medical conditions. Embodiments of the invention may include a particular endoscopic positioning mechanism for placing an endoscope and an additional treatment device within desired body portions in order to assist in diagnosis and treatment of anatomical diseases and disorders. In particular, a medical device according to an embodiment of the invention includes a positioning mechanism configured for movement through at least two degrees of freedom.

Abstract translation: 本发明的实施例包括用于访问患者身体部分并用于诊断和治疗医疗状况的医疗装置。 本发明的实施例可以包括特定的内窥镜定位机构，用于将内窥镜和附加治疗装置放置在期望的身体部分内，以帮助诊断和治疗解剖疾病和病症。 具体地，根据本发明的实施例的医疗装置包括配置成通过至少两个自由度移动的定位机构。

公开(公告)号：US20050288566A1

公开(公告)日：2005-12-29

申请号：US11120436

申请日：2005-05-02

Applicant: Joseph Levendusky ,  Robert Rioux ,  Kurt Geitz ,  Scott Dodson ,  Robert Rauker

Inventor： Joseph Levendusky ,  Robert Rioux ,  Kurt Geitz ,  Scott Dodson ,  Robert Rauker

IPC: A61B1/273 ,  A61B5/04 ,  A61B18/14 ,  A61N1/30

CPC classification number: A61B1/2736 ,  A61B18/1477 ,  A61B18/1492 ,  A61B2018/00083 ,  A61B2018/00482 ,  A61B2018/00702 ,  A61B2018/00875 ,  A61B2018/1497

Abstract: An apparatus for use with a radio frequency generator and an indifferent electrode to treat tissue in a mammalian body includes a needle having a distal portion and being adapted for coupling to the radio frequency generator and a layer of insulating material extending around the needle but exposing a part of the distal portion of the needle. The exposed part of the needle is sized as a function of the thicknesses of the plurality of layers of tissue to facilitate placement of the distal portion of the needle in the plurality of layers by measuring impedance between the needle and the indifferent electrode.

Abstract translation: 用于射频发生器和无关电极以处理哺乳动物体内的组织的装置包括具有远端部分并适于耦合到射频发生器的针和围绕针延伸的一层绝缘材料， 针的远端部分的一部分。 针的暴露部分的大小根据组织的多个层的厚度而变化，以便于通过测量针和无关电极之间的阻抗来将针的远端部分放置在多个层中。

公开(公告)号：US06576005B1

公开(公告)日：2003-06-10

申请号：US09671586

申请日：2000-09-28

Applicant: Kurt Geitz

Inventor： Kurt Geitz

IPC: A61F206

CPC classification number: A61F2/95 ,  A61F2002/9511

Abstract: A stent deployment device for deploying a stent within a body cavity comprises an endoscope having a protective cap, a flexible stent, a sheath, and a flexible, elongated member. The protective cap is mounted on the distal end of the endoscope providing a protected surface for retaining the stent. The flexible stent is circumferentially compressed over the perimeter of the cap, and the sheath is then releasably wrapped around the stent to hold it in a compressed configuration over the cap. The flexible, elongated member, such as a wire extending through a working channel of the endoscope, is attached to either the sheath directly or to a releasing device for the sheath. After the endoscopic device is inserted in a body cavity, the flexible, elongated member is pulled through the working channel to release the sheath and deploy the stent into a desired body opening in the body cavity. After deployment of the stent, the sheath can be left in the body cavity for subsequent retrieval or retracted through the endoscopic device.

Abstract translation: 用于在体腔内部署支架的支架展开装置包括具有保护帽，柔性支架，护套和柔性细长构件的内窥镜。 保护盖安装在内窥镜的远端，提供用于保持支架的保护表面。 柔性支架在盖的周边上周向地压缩，然后将护套可释放地缠绕在支架上以将其保持在帽的压缩构型上。 柔性细长构件，例如延伸穿过内窥镜的工作通道的线，直接附接到护套或用于护套的释放装置。 在将内窥镜装置插入体腔内之后，将柔性的细长构件拉过工作通道以释放护套并将支架展开到体腔中所需的体开口中。 在展开支架之后，护套可以留在体腔中以便随后取出或通过内窥镜装置缩回。

公开(公告)号：US08974622B2

公开(公告)日：2015-03-10

申请号：US13335637

申请日：2011-12-22

Applicant: Claude Clerc ,  Gerald Fredrickson ,  Ralph Barry ,  Paul Norton ,  Kurt Geitz ,  Mike Madden

Inventor： Claude Clerc ,  Gerald Fredrickson ,  Ralph Barry ,  Paul Norton ,  Kurt Geitz ,  Mike Madden

IPC: B32B38/08 ,  A61L31/10 ,  B29C41/08 ,  B29C70/70 ,  B29K83/00 ,  B29K627/18 ,  B29L31/00

CPC classification number: B29C69/00 ,  A61L31/10 ,  B29C41/085 ,  B29C70/70 ,  B29K2021/00 ,  B29K2083/00 ,  B29K2627/18 ,  B29L2031/753 ,  B29L2031/758 ,  C08L27/18 ,  C08L83/04

Abstract: A medical device consists of a stent having a first surface and a second surface parallel to the first surface; a single expanded polytetrafluoroethylene (ePTFE) layer contacting the first surface of the stent; and an elastomeric layer applied to at least one surface of the stent. In at least one embodiment, the elastomeric layer is silicone. In at least one embodiment, the medical device is manufactured by positioning the ePTFE layer such that a first surface of the ePTFE layer contacts a first surface of the stent to form a stent-ePTFE assembly; and applying an elastomeric solution to the first surface of the ePTFE layer and at least one surface of the stent.

Abstract translation: 医疗装置由具有平行于第一表面的第一表面和第二表面的支架构成; 与支架的第一表面接触的单个膨胀聚四氟乙烯（ePTFE）层; 以及应用于支架的至少一个表面的弹性体层。 在至少一个实施方案中，弹性体层是有机硅。 在至少一个实施例中，通过定位ePTFE层使得ePTFE层的第一表面接触支架的第一表面以形成支架ePTFE组件来制造医疗装置; 以及将弹性体溶液施加到所述ePTFE层的第一表面和所述支架的至少一个表面。

公开(公告)号：US20120310226A1

公开(公告)日：2012-12-06

申请号：US13562150

申请日：2012-07-30

Applicant: Michael Fourkas ,  Steven Walak ,  Kurt Geitz ,  Kristine Tatsutani

Inventor： Michael Fourkas ,  Steven Walak ,  Kurt Geitz ,  Kristine Tatsutani

IPC: A61B18/02

CPC classification number: A61B18/02 ,  A61B19/54 ,  A61B90/39 ,  A61B2017/00084 ,  A61B2017/22051 ,  A61B2018/0022 ,  A61B2018/0212 ,  A61B2019/5437 ,  A61B2090/3937

Abstract: A cryogenic tissue ablation instrument includes an elongate flexible body with a proximal supply port for coupling with a pressurized coolant, a supply lumen in communication with the proximal supply port, and an expandable balloon carried on the elongate body. A dispersion member coupled to the elongate body has an interior lumen in communication with the supply lumen, the dispersion member having one or more coolant dispersion apertures sized and located such that a pressurized flowable coolant will enter the balloon interior in the form of a liquid spray that contacts and provides substantially uniform cooling of the balloon.

Abstract translation: 低温组织消融器具包括细长的柔性体，其具有用于与加压的冷却剂联接的近端供应口，与近端供应口连通的供应腔，以及承载在细长体上的可膨胀气囊。 耦合到细长主体的分散部件具有与供应内腔连通的内腔，分散部件具有一个或多个冷却剂分配孔，其尺寸和位置使得加压的可流动的冷却剂将以液体喷雾的形式进入气囊内部 其接触并提供气囊的基本上均匀的冷却。