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公开(公告)号:US20180066095A1
公开(公告)日:2018-03-08
申请号:US15549268
申请日:2016-03-17
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Andrew W. Vail , Jerald K. Rasmussen , John J. Schmidt , Ali E. Ozcam , Jonathan F. Hester , Gregory M. Jellum
IPC: C08F255/02 , G01N1/40 , C12Q1/68 , C12N15/10
CPC classification number: C08F255/02 , C08F220/00 , C12N15/101 , C12N15/1017 , C12Q1/6806 , D06M14/28 , D06M15/263 , D06M15/267 , D06M15/273 , D06M15/3562 , G01N1/4077 , G01N2001/4088
Abstract: A method of purifying a biological composition includes: disposing loose cationic ligand-functionalized staple fibers and a biological composition within a mixing volume of a vessel; agitating the biological composition and the loose cationic ligand-functionalized staple fibers while they are in intimate contact with each other within the mixing volume to provide modified fibers and a purified biological composition; and separating at least a portion of the purified biological composition from the modified fibers and any loose cationic ligand-functionalized staple fibers with which it is in contact. The loose cationic ligand-functionalized staple fibers have a modified surface layer comprising a grafted acrylic polymer comprising 10 to 100 percent by weight of a cationically-ionizable monomer unit. An article for purifying a biological composition includes: a vessel having a mixing volume disposed therein; and the loose cationic ligand-functionalized staple fibers disposed within the mixing volume.
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公开(公告)号:US20240059731A1
公开(公告)日:2024-02-22
申请号:US17766356
申请日:2020-11-24
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Kristopher E. Richardson , Daniel J. O'Neal , Jerald K. Rasmussen , Andrew W. Vail
Abstract: Described herein is a method of purifying a target molecule from an aqueous biological composition, the method comprising: (a) contacting a cationic polymer and the aqueous biological composition to form a mixture comprising a bio-polymer complex and the target molecule in a liquid, wherein the bio-polymer complex has an average particle diameter of at least 45 micrometers, (b) adding the mixture to a filtering volume of a vessel, wherein the vessel comprises loosely packed staple fibers; (c) allowing the mixture to separate through the loosely packed staple fiber; and (d) collecting a filtrate comprising the target molecule.
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公开(公告)号:US11421261B2
公开(公告)日:2022-08-23
申请号:US15733271
申请日:2018-12-17
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Kelvin J. Witcher , Francois Ahimou , Naiyong Jing , Tonya D. Bonilla , Joshua D. Erickson , Hsi-Chou Liu , Andrew W. Vail
Abstract: A method is provided. The method includes providing an article, the article including a nonwoven substrate having a copolymer grafted thereto, the copolymer including interpolymerized monomer units of a quaternary ammonium-containing ligand monomers; an amide monomer; an oxy monomer; and a coating on the nonwoven substrate, the coating including a plurality of test microorganisms, an enzyme or a second substrate; and contacting the article with a detection medium for a period of time.
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公开(公告)号:US20190338335A1
公开(公告)日:2019-11-07
申请号:US16475258
申请日:2017-12-20
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Assumpta A. G. Bennaars-Eiden , Tonya D. Bonilla , Jodi L. Connell , John J. Schmidt , Andrew W. Vail , Federica Sgolastra
Abstract: An article is provided. The article comprises a nonwoven substrate having a copolymer grafted thereto, and a dried coating adhered to the substrate. The copolymer comprises interpolymerized monomer units of a quaternary ammonium-containing ligand monomer, an amide monomer, and an oxy monomer. The coating comprises a plurality of test microorganisms. Optionally, the coating further comprises a water-soluble or water-dispersible polymeric binding agent. A process challenge device comprising a body having a hollow channel with said article fixed disposed therein is also provided. Methods of using the article or the process challenge device for determining the efficacy of a disinfection process are also provided.
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公开(公告)号:US10087405B2
公开(公告)日:2018-10-02
申请号:US14896145
申请日:2014-06-20
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Steven P. Swanson , Jerald K. Rasmussen , George W. Griesgraber , Andrew W. Vail , Andrew S. Waller
Abstract: A wipe article includes a substrate, a cationic coating disposed on a surface of the substrate, distributed throughout the substrate, or both. The cationic coating contains a guanidinyl-containing polymer that is crosslinked and bound to the substrate. The substrate includes sponge, nonwoven fabric, or woven fabric. The wipes are useful for removing microorganisms from a microorganism-contaminated surface and also for reducing re-contamination of the cleaned surface or transfer to another surface of the removed microorganisms.
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公开(公告)号:US20160115430A1
公开(公告)日:2016-04-28
申请号:US14896145
申请日:2014-06-20
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Steven P. Swanson , Jerald K. Rasmussen , George W. Griesgraber , Andrew W. Vail , Andrew S. Waller
CPC classification number: C11D17/049 , A01N47/44 , A47L13/17 , B08B1/00 , B08B1/006 , A01N25/10 , A01N25/34
Abstract: A wipe article includes a substrate, a cationic coating disposed on a surface of the substrate, distributed throughout the substrate, or both. The cationic coating contains a guanidinyl-containing polymer that is crosslinked and bound to the substrate. The substrate includes sponge, nonwoven fabric, or woven fabric. The wipes are useful for removing microorganisms from a microorganism-contaminated surface and also for reducing re-contamination of the cleaned surface or transfer to another surface of the removed microorganisms.
Abstract translation: 擦拭物品包括基底,设置在基底的表面上的阳离子涂层,分布在整个基底上,或两者。 阳离子涂层含有交联并与基底结合的含胍基的聚合物。 基材包括海绵,无纺织物或机织织物。 擦拭物可用于从微生物污染的表面除去微生物并且还用于减少清洁表面的再污染或转移到除去的微生物的另一表面。
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公开(公告)号:US20240066162A1
公开(公告)日:2024-02-29
申请号:US18259602
申请日:2022-02-15
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Andrew W. Vail , Saurabh Batra , Jodi L. Connell , Robert A. Schmitz
IPC: A61L2/18 , A01N25/10 , A01N25/34 , A47L13/17 , D04H1/4291 , D04H1/4382 , D04H3/16
CPC classification number: A61L2/18 , A01N25/10 , A01N25/34 , A47L13/17 , D04H1/4291 , D04H1/43838 , D04H3/16 , A61L2202/15 , D10B2321/022 , D10B2401/022 , D10B2401/04 , D10B2509/00
Abstract: Described herein is a nonwoven wipe comprising a plurality of polyolefin fibers, wherein the plurality of polyolefin fibers have an average fiber diameter of at least 200 nm and at most 3.5 micrometers, and wherein the plurality of polyolefin fibers have a basis weight of at least 20 and no more than 100 grams per square meter. Such nonwoven wipes can be used with an aqueous solution, optionally comprising an active ingredient, to decontaminate a surface. Also disclosed herein in a decontamination kit providing the same and a method of decontaminating a surface.
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公开(公告)号:US20240010674A1
公开(公告)日:2024-01-11
申请号:US18251412
申请日:2021-11-08
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Kristopher E. Richardson , Daniel J. O'Neal , Jerald K. Rasmussen , Andrew W. Vail , Alexei M. Voloshin
CPC classification number: C07K1/32 , C07K1/34 , C07K1/36 , C07K16/065 , B01D39/1623 , B01D71/56 , B01D37/00 , B01D2239/0618 , B01D2239/0622 , B01D2239/1233 , B01D2239/1266 , B01D2239/1216
Abstract: Described herein is a method of purifying a target molecule from an aqueous biological composition, the method comprising: (a) contacting a cationic polymer and the aqueous biological composition to form a mixture, the mixture comprising a bio-polymer complex and the target non-binding molecule in a liquid, wherein the bio-polymer complex has an average particle diameter of at least 50 micrometers; (b) providing a filtering unit comprising (i) a housing having an inlet and an outlet, (ii) a porous, continuous filter medium which is fluidly connected to the inlet and the outlet, and (iii) a collection region upstream from the porous, continuous filter medium; (c) adding the mixture to the inlet; and (d) allowing the mixture to separate in the filtering unit, whereby the bio-polymer complex collects in the collection region and the target non-binding molecule passes through the filter medium, and wherein the majority of flow of the liquid through the porous, continuous filter medium is not substantially parallel with the direction of gravity.
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公开(公告)号:US20230302178A1
公开(公告)日:2023-09-28
申请号:US18023112
申请日:2021-08-26
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Andrew W. Vail , Robert A. Schmitz
IPC: A61L2/18
CPC classification number: A61L2/18 , A61L2101/18
Abstract: A method of removing pathogens from a surface is described. In particular, a method including providing a wipe including guanidinyl-containing polymer coating, providing a liquid disinfectant having an associated disinfection time t for at least one pathogen is described. The method may help provide safe levels of disinfection even with a significant associated error in dwell time.
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公开(公告)号:US11629371B2
公开(公告)日:2023-04-18
申请号:US16475258
申请日:2017-12-22
Applicant: 3M INNOVATIVE PROPERTIES COMPANY
Inventor: Assumpta A. G. Bennaars-Eiden , Tonya D. Bonilla , Jodi L. Connell , John J. Schmidt , Andrew W. Vail , Federica Sgolastra
IPC: G01N15/06 , C12Q1/22 , A61L2/28 , C11D17/04 , A47L13/17 , A61L2/00 , D06M14/26 , D06M14/00 , A01N47/44
Abstract: An article is provided. The article comprises a nonwoven substrate having a copolymer grafted thereto, and a dried coating adhered to the substrate. The copolymer comprises interpolymerized monomer units of a quaternary ammonium-containing ligand monomer, an amide monomer, and an oxy monomer. The coating comprises a plurality of test microorganisms. Optionally, the coating further comprises a water-soluble or water-dispersible polymeric binding agent. A process challenge device comprising a body having a hollow channel with said article fixed disposed therein is also provided. Methods of using the article or the process challenge device for determining the efficacy of a disinfection process are also provided.
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