公开(公告)号：US09415416B2

公开(公告)日：2016-08-16

申请号：US14052986

申请日：2013-10-14

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Laura Melton Kalvass

IPC: B05C11/00 ,  B05B13/04 ,  A61F2/82 ,  B05D1/00

CPC classification number: B05C11/00 ,  A61F2/82 ,  A61L2420/02 ,  B05B13/0442 ,  B05D1/002

Abstract: A systems and method for reducing coating defects on a stent may involve a support apparatus comprising wire cage for carrying a stent. The support apparatus may have no structure that extends inside the stent. A support apparatus may include a plurality of wires that pass through the stent but do not pass through the midplane of the stent. A support apparatus may contact only the proximal ends of the stent. The method may involve keeping the stent in motion during a spray coating process to prevent the stent from having a point remain in continuous contact with a support apparatus.

Abstract translation: 用于减少支架上的涂层缺陷的系统和方法可以涉及包括用于承载支架的线架的支撑装置。 支撑装置可以没有在支架内延伸的结构。 支撑装置可以包括穿过支架但不穿过支架的中平面的多根线。 支撑装置可以仅接触支架的近端。 该方法可以包括在喷雾涂覆过程期间保持支架运动，以防止支架保持与支撑装置的连续接触。

公开(公告)号：US09408949B2

公开(公告)日：2016-08-09

申请号：US14476623

申请日：2014-09-03

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Syed F. A. Hossainy ,  Yiwen Tang ,  Eugene T. Michal ,  Thierry Glauser ,  Stephen D. Pacetti ,  Jessica DesNoyer

IPC: A61F13/00 ,  A61L31/10 ,  A61L31/14 ,  A61L31/16 ,  A61L29/08 ,  A61L31/08 ,  A61L27/28 ,  A61L27/34

CPC classification number: A61L31/10 ,  A61F2250/0067 ,  A61L27/28 ,  A61L27/34 ,  A61L29/08 ,  A61L29/085 ,  A61L31/08 ,  A61L31/148 ,  A61L31/16 ,  A61L2420/00 ,  A61L2420/02 ,  A61L2420/06 ,  C08L67/04

Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid.

Abstract translation: 公开了用于可植入医疗装置的涂层及其制造方法，所述涂层包含乳酸聚合物。

公开(公告)号：US20160213501A1

公开(公告)日：2016-07-28

申请号：US15064262

申请日：2016-03-08

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Yunbing Wang

IPC: A61F2/915 ,  B22D27/00 ,  B22D21/00 ,  B22D25/02 ,  B23K26/38 ,  B23K26/40

CPC classification number: A61F2/915 ,  A61F2/82 ,  A61F2210/0004 ,  A61F2210/0009 ,  A61F2240/001 ,  A61F2250/003 ,  A61F2310/00041 ,  A61L31/022 ,  A61L31/086 ,  A61L31/088 ,  A61L31/10 ,  A61L31/124 ,  A61L31/148 ,  A61L2300/416 ,  A61L2300/606 ,  A61L2400/18 ,  B22D21/007 ,  B22D25/02 ,  B22D27/00 ,  B23K26/38 ,  B23K26/40 ,  B23K2103/15 ,  C23C8/00 ,  C23C8/10 ,  C23C8/42 ,  C23C8/80 ,  C23C26/00 ,  C23C28/04 ,  C23C28/30 ,  C23C30/00

Abstract: Stents or scaffolds made from magnesium or magnesium alloys including additives or barrier coatings that modify the corrosion rate of the stent are disclosed. Methods of forming barrier coatings that modify the corrosion rate of the stent are disclosed.

公开(公告)号：US09345815B2

公开(公告)日：2016-05-24

申请号：US14311174

申请日：2014-06-20

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen R. Dugan ,  Jessica R. DesNoyer ,  Stephen D. Pacetti ,  Bozena Zofia Maslanka

IPC: A61F2/06 ,  A61L31/14 ,  A61F2/86 ,  A61F2/958 ,  A61L31/10 ,  A61L31/16 ,  A61L29/14

CPC classification number: A61L31/10 ,  A61F2/844 ,  A61F2/86 ,  A61F2/915 ,  A61F2/958 ,  A61F2002/91533 ,  A61F2002/91583 ,  A61L29/14 ,  A61L31/14 ,  A61L31/16 ,  A61L2300/426 ,  A61L2400/10 ,  A61L2420/02 ,  A61L2420/08

Abstract: A medical assembly is disclosed comprises a stent and a catheter having a balloon, wherein the coefficient of friction and/or the adhesion at the stent/balloon interface are reduced.

Abstract translation: 所公开的医疗组件包括支架和具有气囊的导管，其中减小了支架/球囊界面处的摩擦系数和/或粘附力。

公开(公告)号：US09220815B2

公开(公告)日：2015-12-29

申请号：US13963792

申请日：2013-08-09

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti

IPC: C08L27/12 ,  C08L23/04 ,  A61L31/04 ,  A61L31/10 ,  A61L31/16 ,  C08F214/18 ,  C08F295/00 ,  C09D127/16 ,  A61K31/436

CPC classification number: A61L31/048 ,  A61K31/436 ,  A61L31/10 ,  A61L31/16 ,  A61L2300/416 ,  C08F214/18 ,  C08F295/00 ,  C09D127/16 ,  C08L27/12 ,  A61K31/10

Abstract: It is provided a polymer blend that contains a polymer formed of fluorinated monomers and hydrocarbon monomers and another biocompatible polymer.

Abstract translation: 提供了一种聚合物共混物，其包含由氟化单体和烃单体形成的聚合物和另一种生物相容性聚合物。

公开(公告)号：US20150359648A1

公开(公告)日：2015-12-17

申请号：US14307440

申请日：2014-06-17

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Xiao Ma ,  Mary Beth Kossuth ,  James P. Oberhauser ,  Stephen D. Pacetti ,  Manish Gada

IPC: A61F2/90 ,  A61L31/04 ,  A61L31/06 ,  A61L31/14 ,  A61F2/91

CPC classification number: A61F2/90 ,  A61F2/91 ,  A61L31/041 ,  A61L31/06 ,  A61L31/148

Abstract: Bioresorbable polymer vascular scaffolds made of combinations of polylactide and polycaprolactone having a high molecular weight polymer, thin struts in a selected range and sufficient radial strength to support a vessel upon deployment. The scaffolds have degradation behavior of molecular weight, radial strength, and mass that are conducive to healing of a vessel including providing patency to a vessel, reduction of radial strength, breaking up, and resorbing to allow return of the vessel to a natural state.

Abstract translation: 由具有高分子量聚合物的聚丙交酯和聚己内酯的组合制成的可生物再吸收的聚合物血管支架，在选定范围内的薄支柱和足够的径向强度以在部署时支撑血管。 支架具有有助于血管愈合的分子量，径向强度和质量的降解行为，包括向容器提供通畅性，降低径向强度，分解和再吸收以允许血管返回到自然状态。

公开(公告)号：US20150282969A1

公开(公告)日：2015-10-08

申请号：US14702525

申请日：2015-05-01

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Stephen D. Pacetti

IPC: A61F2/958 ,  A61F2/06

CPC classification number: A61F2/958 ,  A61F2/06 ,  A61F2/07 ,  A61F2/82 ,  A61F2002/9522 ,  A61F2240/001 ,  A61L31/022 ,  A61L31/048 ,  A61L31/16 ,  A61L2300/416 ,  A61L2420/06 ,  B05C11/00 ,  B21D39/048 ,  Y10T29/49863 ,  Y10T29/49865 ,  Y10T29/49925 ,  Y10T29/49927 ,  Y10T29/53996

Abstract: A method for crimping a bioabsorbable stent in a humid environment is disclosed.

Abstract translation: 公开了一种在潮湿环境下卷曲生物可吸收支架的方法。

公开(公告)号：US09090745B2

公开(公告)日：2015-07-28

申请号：US14081287

申请日：2013-11-15

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Stephen D. Pacetti ,  Mikael Trollsas

IPC: A61F2/00 ,  A61F13/00 ,  A61K38/00 ,  A61F2/04 ,  C08G81/00 ,  A61L29/04 ,  A61L29/16 ,  A61L31/04 ,  A61L31/16 ,  A61K31/436 ,  A61L31/06

CPC classification number: A61L31/10 ,  A61K31/436 ,  A61L29/041 ,  A61L29/16 ,  A61L31/048 ,  A61L31/06 ,  A61L31/16 ,  A61L2300/606 ,  A61L2420/00 ,  C08G81/00

Abstract: The present invention is directed to polymeric materials made of biodegradable, bioabsorbable triblock copolymers and implantable devices (e.g., drug-delivery stents) containing such polymeric materials. The polymeric materials may also contain at least one therapeutic substance. The polymeric materials are formulated so as to improve the mechanical and adhesion properties, degradation, biocompatibility and drug permeability of such materials and, thus, implantable devices formed of such materials.

公开(公告)号：US09072665B2

公开(公告)日：2015-07-07

申请号：US13737842

申请日：2013-01-09

Applicant: Abbott Cardiovascular Systems Inc.

Inventor： Florian N. Ludwig ,  Syed F. A. Hossainy ,  Stephen D. Pacetti

IPC: A61K9/127 ,  A61K9/51 ,  A61K9/00 ,  A61K47/48 ,  B82Y5/00

CPC classification number: A61K9/0087 ,  A61K47/6907 ,  A61K47/6911 ,  A61K47/6913 ,  A61K47/6915 ,  A61K47/6935 ,  B82Y5/00

Abstract: A composition that includes nanoparticles with binding affinity for platelets, and methods for using this composition to treat vascular disease are disclosed.

Abstract translation: 公开了包含对血小板具有结合亲和力的纳米颗粒的组合物，以及使用该组合物治疗血管疾病的方法。

公开(公告)号：US09044312B2

公开(公告)日：2015-06-02

申请号：US14268834

申请日：2014-05-02

Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.

Inventor： Stephen D. Pacetti

IPC: A61F2/82 ,  A61F2/06 ,  B21D39/04 ,  A61F2/958 ,  B05C11/00 ,  A61F2/95

CPC classification number: A61F2/958 ,  A61F2/06 ,  A61F2/07 ,  A61F2/82 ,  A61F2002/9522 ,  A61F2240/001 ,  A61L31/022 ,  A61L31/048 ,  A61L31/16 ,  A61L2300/416 ,  A61L2420/06 ,  B05C11/00 ,  B21D39/048 ,  Y10T29/49863 ,  Y10T29/49865 ,  Y10T29/49925 ,  Y10T29/49927 ,  Y10T29/53996

Abstract: An apparatus is disclosed including a workspace for receiving a stent and a delivery device for the stent; a source for exposing the stent in the workspace to a plasticizing agent, vapor, or moisture, wherein the stent can be reduced in diameter in the workspace while under exposure of the plasticizing agent, vapor or moisture; and a device for reducing the diameter of the stent in the workspace to position the stent on or within the delivery device.

Abstract translation: 公开了一种包括用于接收支架的工作空间和用于支架的输送装置的装置; 用于将工作空间中的支架暴露于塑化剂，蒸汽或水分的源，其中在塑化剂，蒸气或水分暴露的同时，支架可以在工作空间中直径减小; 以及用于在工作空间中减小支架的直径以将支架定位在输送装置上或内部的装置。