公开(公告)号：US20240018952A1

公开(公告)日：2024-01-18

申请号：US18465810

申请日：2023-09-12

Applicant: Cytiva Sweden AB

Inventor： Andreas Torbjorn Lundin ,  Klas Marteleur ,  Mats Lundkvist ,  Andreas Marcstrom ,  David Gronowitz

IPC: F04B1/047 ,  F04B43/02

CPC classification number: F04B1/047 ,  F04B43/026 ,  F04B43/02

Abstract: A multiple cavity reciprocating positive displacement pump comprising plural pump cavities each including at least one pair of one-way valves the at least one pair including an inlet valve and an outlet valve, the pump being characterised in that respective inlet valves are in fluid communication with a common inlet and respective outlet valves are in fluid communication with a common outlet. The multiple cavities may include diaphragm arranged in a radial configuration for more uniform pressure output.

公开(公告)号：US11815075B2

公开(公告)日：2023-11-14

申请号：US16645022

申请日：2018-09-06

Applicant: Cytiva Sweden AB

Inventor： Andreas Torbjorn Lundin ,  Klas Marteleur ,  Mats Lundkvist ,  Andreas Marcstrom ,  David Gronowitz

IPC: F04B1/047 ,  F04B43/02

CPC classification number: F04B1/047 ,  F04B43/02 ,  F04B43/026

Abstract: A multiple cavity reciprocating positive displacement pump (200) comprises a plurality of pump cavities (222), each pump cavity (222) including at least an inlet valve (228) and an outlet valve (231), wherein respective inlet valves (228) are in fluid communication with a common inlet (224) and respective outlet valves (231) are in fluid communication with a common outlet (238), and wherein the pump cavities (222) are arranged about a pump axis (AR) and around said common inlet (224) and said common outlet (238).

公开(公告)号：US11280722B2

公开(公告)日：2022-03-22

申请号：US17056543

申请日：2019-05-29

Applicant: Cytiva Sweden AB

Inventor： Hanno Ehring ,  Mats Lundkvist ,  David Carl Martin Bergman ,  Andreas Marcstrom

IPC: G01N21/00 ,  G01N21/05 ,  G01N21/03 ,  G01N21/85

Abstract: Disclosed is an optical flow cell (300′) comprising: a housing (910) forming; an enclosed and elongated fluid channel (920) arranged along a first axis (923); a first light guide (961) and a second light guide (962) generally concentrically arranged along a second axis (970) and on opposite side walls of the fluid channel, said first and second light guides having ends (961c,962c) removed in situ to provide a sensing gap (d).

公开(公告)号：US11224827B2

公开(公告)日：2022-01-18

申请号：US16348581

申请日：2017-11-10

Applicant: Cytiva Sweden AB

Inventor： Mats Lundkvist ,  Daniel Salomonsson

IPC: B01D15/22 ,  B32B1/08 ,  B32B3/06 ,  B32B7/12 ,  B32B27/08 ,  B32B27/30 ,  B32B27/32 ,  B32B37/12 ,  B32B37/18 ,  G01N30/60 ,  G01N30/02

Abstract: Disclosed is a chromatography column cylinder (200) formed from a polymer composite comprising an outer layer (220) and inner layer (210) intended to be in direct contact with the intended contents of the cylinder in a volume (202), wherein the outer layer supports the inner layer, for example when there is negative pressure in the volume (202). In one embodiment, one of said layers is molded directly onto a surface of the other layer such that there is no gap between the two layers. Disclosed also is a method for forming a chromatography column cylinder.

公开(公告)号：US20210222681A1

公开(公告)日：2021-07-22

申请号：US16645022

申请日：2018-09-06

Applicant: Cytiva Sweden AB

Inventor： Andreas Torbjorn Lundin ,  Klas Marteleur ,  Mats Lundkvist ,  Andreas Marcstrom ,  David Gronowitz

IPC: F04B1/047 ,  F04B43/02

Abstract: A multiple cavity reciprocating positive displacement pump (200) comprises a plurality of pump cavities (222), each pump cavity (222) including at least an inlet valve (228) and an outlet valve (231), wherein respective inlet valves (228) are in fluid communication with a common inlet (224) and respective outlet valves (231) are in fluid communication with a common outlet (238), and wherein the pump cavities (222) are arranged about a pump axis (AR) and around said common inlet (224) and said common outlet (238).

公开(公告)号：US12072344B2

公开(公告)日：2024-08-27

申请号：US18131043

申请日：2023-04-05

Applicant: Cytiva Sweden AB

Inventor： Johan Blomberg ,  Mats Lundkvist

IPC: G01N35/10 ,  B01D15/10 ,  B01D29/60 ,  G01N30/24 ,  G01N30/38 ,  G01N30/88 ,  B01D15/08 ,  B01D17/12 ,  G01N30/02 ,  G01N35/00

CPC classification number: G01N35/1097 ,  B01D15/10 ,  B01D29/60 ,  G01N30/24 ,  G01N30/38 ,  G01N30/88 ,  B01D15/08 ,  B01D17/12 ,  B01D2201/54 ,  G01N2030/027 ,  G01N2030/8804 ,  G01N2030/8881 ,  G01N2035/00326 ,  Y10T137/6416 ,  Y10T137/6525 ,  Y10T137/6851 ,  Y10T137/85986 ,  Y10T137/87885

Abstract: Automated fluid handling system comprising a housing and two or more fluid handling units arranged as interchangeable modular components with an external fluidics section and an internal non fluidics section, and wherein the housing comprises a liquid handling panel with two or more of component positions for receiving said interchangeable modular components such that the external fluidics section is separated from the non fluidics section by the liquid handling panel.

公开(公告)号：US11686712B2

公开(公告)日：2023-06-27

申请号：US17727375

申请日：2022-04-22

Applicant: CYTIVA SWEDEN AB

Inventor： Stefan Dargy ,  Olle Bjernulf ,  Mats Lundkvist

IPC: G01N30/80 ,  G01N35/10 ,  G01N35/02 ,  G01N30/02 ,  G01N35/04

CPC classification number: G01N30/80 ,  G01N35/025 ,  G01N35/1011 ,  G01N2030/027 ,  G01N2035/0439

Abstract: Disclosed is a fraction collector for dispensing liquids into plural receptacles (P1,P2) arranged in a two dimensional array. The fraction collector comprises a table (22) for supporting said receptacles, and an arm supported above the table, in tum supporting a liquid dispenser (35), the fraction collector arm is rotatable about an arm axis (C) and the liquid dispenser is movable along the arm on a carriage 34 (FIG. 2). Thereby, the dispenser is low cost and is repositionable simply above the receptacles as a result of said rotation and as a result of said movement along the arm, without occupying too much laboratory bench space.

公开(公告)号：US11650219B2

公开(公告)日：2023-05-16

申请号：US16788836

申请日：2020-02-12

Applicant: CYTIVA SWEDEN AB

Inventor： Johan Blomberg ,  Mats Lundkvist

IPC: G01N35/10 ,  B01D15/10 ,  G01N30/88 ,  B01D29/60 ,  G01N30/24 ,  G01N30/38 ,  B01D15/08 ,  B01D17/12 ,  G01N35/00 ,  G01N30/02

CPC classification number: G01N35/1097 ,  B01D15/10 ,  B01D29/60 ,  G01N30/24 ,  G01N30/38 ,  G01N30/88 ,  B01D15/08 ,  B01D17/12 ,  B01D2201/54 ,  G01N2030/027 ,  G01N2030/8804 ,  G01N2030/8881 ,  G01N2035/00326 ,  Y10T137/6416 ,  Y10T137/6525 ,  Y10T137/6851 ,  Y10T137/85986 ,  Y10T137/87885

Abstract: Automated fluid handling system comprising a housing and two or more fluid handling units arranged as interchangeable modular components with an external fluidics section and an internal non fluidics section, and wherein the housing comprises a liquid handling panel with two or more of component positions for receiving said interchangeable modular components such that the external fluidics section is separated from the non fluidics section by the liquid handling panel.

公开(公告)号：US12017215B2

公开(公告)日：2024-06-25

申请号：US16486736

申请日：2018-02-27

Applicant: Cytiva Sweden AB

Inventor： Tuomo Valtteri Frigard ,  Robert Magnusson ,  Mats Lundkvist ,  Karl Axel Jakob Liderfelt ,  Helena Nordvarg ,  Andreas Torbjorn Lundin ,  Peter Arne Reffner

IPC: B01L3/00 ,  B01D15/10 ,  B01D61/14

CPC classification number: B01L3/502715 ,  B01D15/10 ,  B01D61/145 ,  B01L3/502738 ,  B01L3/502761 ,  B01D2311/2626 ,  B01D2315/16 ,  B01L2200/028 ,  B01L2200/0647 ,  B01L2300/0627 ,  B01L2300/0809 ,  B01L2300/0864 ,  B01L2400/06

Abstract: Disclosed is a modular bio-processing unit (100) comprising: a housing (110) having one or more internal fluid paths (101), the housing having at least one inlet and at least one outlet (5,10,15,20,25,30,35,40,45,50,55,60,65,70), each in fluid communication with the fluid path or one or more of the fluid paths; one or more sensor elements (120,150,170,190) operatively associated with the or each path, said sensor(s) elements including elements of one or more of: a flow sensor, a flow rate sensor, a conductivity sensor, a pressure sensor, a pH sensor, and a light absorbance sensor such as a UV spectroscopic concentration sensor; one or more fluid flow inducing components (140) operatively associated with the or each fluid path; and plural valves (180) for preventing or reducing flow in the or each path, the housing, inlet(s), outlet(s), flow inducing component(s) and valve(s) being arranged to operate together as a bio-processing unit within or substantially within the housing.

公开(公告)号：US20230347262A1

公开(公告)日：2023-11-02

申请号：US17997874

申请日：2021-06-21

Applicant: CYTIVA SWEDEN AB

Inventor： Mats Lundkvist ,  Tomas Yngve Agren ,  Erik Nilsson ,  Sebastian Skoglund

IPC: B01D15/24

CPC classification number: B01D15/247

Abstract: The invention relates to a fraction collector apparatus (100) comprising: a support system (1, 2), a carrier (42) moveably supported by the support system (1, 2), an extension arm (3) connected to the carrier (42), at least one dispensing head (31) for dispensing droplets and moveably connected to the extension arm (3), wherein the dispensing head (31) and (carrier 42) are configured to move relative to the support system in a first plane, a tray area (11) designed to support at least one rack (6, 7), wherein the at least one rack (6, 7) is designed to hold at least one collection vessel (12, 14), wherein motion of said carrier (42) is achieved by a linear bearing Y-slide unit (41) wherein the linear bearing Y-slide unit (41) is arranged underneath a linear bearing Y-rail (40) and wherein the carrier (42) is attached to the linear bearing Y-slide unit (41).