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    STRUCTURES INCORPORATING CONFORMATIONALLY FLEXIBLE CONJUGATED POLYMERS AND METHODS OF USE
    11.
    发明申请
    STRUCTURES INCORPORATING CONFORMATIONALLY FLEXIBLE CONJUGATED POLYMERS AND METHODS OF USE 有权
    具有连续柔性结合聚合物的结构和使用方法

    公开(公告)号：US20110183439A1

    公开(公告)日：2011-07-28

    申请号：US13075172

    申请日：2011-03-29

    Applicant: Guillermo C. Bazan ,  Bin Liu

    Inventor： Guillermo C. Bazan ,  Bin Liu

    IPC: G01N33/543 ,  C08F283/00

    CPC classification number: H01B1/122 ,  C08G61/02 ,  C08G61/10 ,  C08G61/123 ,  C08G61/126 ,  C08G73/02 ,  C08G73/08 ,  C40B40/04

    Abstract: Methods, compositions and articles of manufacture involving conformationally flexible conjugated polymers are provided. A structure is provided comprising the conformationally flexible conjugated polymer bound to or associated with at least one member of a binding pair comprising a sensor molecule and a target molecule or the complex they form. The conformationally flexible conjugated polymer comprises at least one angled linker having bonds to its two adjacent polymeric units which form an angle of less than about 155° with respect to one another. Methods of use of such structures and solutions comprising them are also provided.

    Abstract translation: 提供涉及构象柔性共轭聚合物的方法，组合物和制品。 提供了包含结构柔性共轭聚合物结构或与至少一个包含传感器分子和靶分子或其形成的复合物的结合对成员相关联的结构。 构象柔性的共轭聚合物包括至少一个成角度的连接体，其具有与其两个相邻的聚合物单元的键合，其相对于彼此形成小于约155°的角度。 还提供了使用这种结构的方法和包括它们的溶液。

    Conformationally flexible cationic conjugated polymers
    12.
    发明授权
    Conformationally flexible cationic conjugated polymers 有权
    构象柔性阳离子共轭聚合物

    公开(公告)号：US07914984B2

    公开(公告)日：2011-03-29

    申请号：US11561893

    申请日：2006-11-21

    Applicant: Guillermo C Bazan ,  Bin Liu

    Inventor： Guillermo C Bazan ,  Bin Liu

    IPC: C08F297/02

    CPC classification number: H01B1/122 ,  C08G61/02 ,  C08G61/10 ,  C08G61/123 ,  C08G61/126 ,  C08G73/02 ,  C08G73/08 ,  C40B40/04

    Abstract: Methods, compositions and articles of manufacture involving cationic conjugated conformationally flexible polymers are provided. A method for the synthesis of cationic water-soluble polymers with linkages along the polymer main chain structure which disrupt the ability of the polymers to form extended-rod structures is provided. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

    Abstract translation: 提供涉及阳离子共轭构象柔性聚合物的方法，组合物和制品。 提供了一种用于合成阳离子水溶性聚合物的方法，所述聚合物具有沿聚合物主链结构的连接，其破坏聚合物形成延伸棒结构的能力。 这种聚合物可用于制造新的光电器件和开发高效生物传感器。 本发明还涉及这些聚合物在测定方法中的应用。

    Methods for assaying a sample for an aggregant
    14.
    发明授权
    Methods for assaying a sample for an aggregant 有权
    测定聚集体样品的方法

    公开(公告)号：US07666594B2

    公开(公告)日：2010-02-23

    申请号：US11344942

    申请日：2006-01-31

    Applicant: Guillermo C. Bazan ,  Bin Liu

    Inventor： Guillermo C. Bazan ,  Bin Liu

    IPC: C12Q1/68 ,  G01N33/53

    CPC classification number: G01N21/6486 ,  C08G61/02 ,  C08G61/123 ,  C12Q1/6818 ,  C12Q1/6825 ,  G01N33/542 ,  G01N33/54373 ,  Y10T436/143333 ,  C12Q2565/113 ,  C12Q2563/173 ,  C12Q2565/101

    Abstract: This invention relates to an aggregation sensor useful for the detection and analysis of aggregants in a sample, and methods, articles and compositions relating to such a sensor. The sensor comprises first and second optically active units, where energy may be transferred from an excited state of the first optically active unit to the second optically active unit. The second optically active unit is present in a lesser amount, but its relative concentration is increased upon aggregation, increasing its absorption of energy from the first optically active units. This increase in energy transfer can be detected in variety of formats to produce an aggregation sensing system for various aggregants, including for quantitation. Other variations of the inventions are described further herein.

    Abstract translation: 本发明涉及可用于检测和分析样品中的聚集体的聚集传感器，以及与这种传感器相关的方法，制品和组合物。 传感器包括第一和第二光学有源单元，其中能量可以从第一光学活性单元的激发状态转移到第二光学活性单元。 第二光学活性单元以较小的量存在，但是其聚集时其相对浓度增加，从而增加其从第一光学活性单元的能量吸收。 可以以各种格式检测能量转移的这种增加，以产生用于各种聚合物的聚集感测系统，包括用于定量。 本文进一步描述了本发明的其它变型。

    Methods and compositions for assaying a sample for an aggregant
    16.
    发明授权
    Methods and compositions for assaying a sample for an aggregant 有权
    用于测定聚集体样品的方法和组合物

    公开(公告)号：US08546081B2

    公开(公告)日：2013-10-01

    申请号：US13367358

    申请日：2012-02-06

    Applicant: Guillermo C. Bazan ,  Bin Liu

    Inventor： Guillermo C. Bazan ,  Bin Liu

    IPC: C12Q1/68 ,  G01N33/53

    CPC classification number: G01N21/6486 ,  C08G61/02 ,  C08G61/123 ,  C12Q1/6818 ,  C12Q1/6825 ,  G01N33/542 ,  G01N33/54373 ,  Y10T436/143333 ,  C12Q2565/113 ,  C12Q2563/173 ,  C12Q2565/101

    Abstract: This invention relates to an aggregation sensor useful for the detection and analysis of aggregants in a sample, and methods, articles and compositions relating to such a sensor. The sensor comprises first and second optically active units, where energy may be transferred from an excited state of the first optically active unit to the second optically active unit. The second optically active unit is present in a lesser amount, but its relative concentration is increased upon aggregation, increasing its absorption of energy from the first optically active units. This increase in energy transfer can be detected in variety of formats to produce an aggregation sensing system for various aggregants, including for quantitation. Other variations of the inventions are described further herein.

    Abstract translation: 本发明涉及可用于检测和分析样品中的聚集体的聚集传感器，以及与这种传感器相关的方法，制品和组合物。 传感器包括第一和第二光学有源单元，其中能量可以从第一光学活性单元的激发状态转移到第二光学活性单元。 第二光学活性单元以较小的量存在，但是其聚集时其相对浓度增加，从而增加其从第一光学活性单元的能量吸收。 可以以各种格式检测能量转移的这种增加，以产生用于各种聚合物的聚集感测系统，包括用于定量。 本文进一步描述了本发明的其它变型。

    Conformationally flexible cationic conjugated polymers
    17.
    发明授权
    Conformationally flexible cationic conjugated polymers 有权
    构象柔性阳离子共轭聚合物

    公开(公告)号：US07144950B2

    公开(公告)日：2006-12-05

    申请号：US10666333

    申请日：2003-09-17

    Applicant: Guillermo C. Bazan ,  Bin Liu

    Inventor： Guillermo C. Bazan ,  Bin Liu

    IPC: C08F36/04 ,  C08F283/14 ,  C08L47/00

    CPC classification number: H01B1/122 ,  C08G61/02 ,  C08G61/10 ,  C08G61/123 ,  C08G61/126 ,  C08G73/02 ,  C08G73/08 ,  C40B40/04

    Abstract: Methods, compositions and articles of manufacture involving cationic conjugated conformationally flexible polymers are provided. A method for the synthesis of cationic water-soluble polymers with linkages along the polymer main chain structure which disrupt the ability of the polymers to form extended-rod structures is provided. Such polymers may serve in the fabrication of novel optoelectronic devices and in the development of highly efficient biosensors. The invention further relates to the application of these polymers in assay methods.

    Abstract translation: 提供涉及阳离子共轭构象柔性聚合物的方法，组合物和制品。 提供了一种用于合成阳离子水溶性聚合物的方法，所述聚合物具有沿聚合物主链结构的连接，其破坏聚合物形成延伸棒结构的能力。 这种聚合物可用于制造新的光电器件和开发高效生物传感器。 本发明还涉及这些聚合物在测定方法中的应用。

    Card box
    18.
    外观设计
    Card box 有权

    公开(公告)号：USD1046613S1

    公开(公告)日：2024-10-15

    申请号：US29863052

    申请日：2022-12-15

    Applicant: Bin Liu

    Designer： Bin Liu

    Abstract: FIG. 1 is a front and top perspective view of a card box showing my new design;
    FIG. 2 is a front view thereof;
    FIG. 3 is a rear view thereof;
    FIG. 4 is a left view thereof;
    FIG. 5 is a right view thereof;
    FIG. 6 is a top view thereof;
    FIG. 7 is a bottom view thereof;
    FIG. 8 is a partially exploded perspective view thereof, showing a top portion removed, and a middle portion and a bottom portion partially assembled;
    FIG. 9 is an exploded perspective view thereof, showing a top, middle and a bottom portion; and,
    FIG. 10 is an exploded perspective view thereof.

    Semiconductor devices having gate structures and methods of manufacturing the same
    20.
    发明授权
    Semiconductor devices having gate structures and methods of manufacturing the same 有权
    具有栅极结构的半导体器件及其制造方法

    公开(公告)号：US09590099B2

    公开(公告)日：2017-03-07

    申请号：US14859447

    申请日：2015-09-21

    Applicant: Bin Liu ,  Sun-Min Kim ,  Shigenobu Maeda

    Inventor： Bin Liu ,  Sun-Min Kim ,  Shigenobu Maeda

    IPC: H01L29/66 ,  H01L29/78 ,  H01L29/08 ,  H01L29/161 ,  H01L29/167 ,  H01L29/423 ,  H01L29/51 ,  H01L29/786 ,  H01L29/10 ,  H01L29/06 ,  H01L21/324

    CPC classification number: H01L29/7833 ,  H01L21/324 ,  H01L29/0649 ,  H01L29/0847 ,  H01L29/1054 ,  H01L29/161 ,  H01L29/167 ,  H01L29/42364 ,  H01L29/513 ,  H01L29/66545 ,  H01L29/785 ,  H01L29/78684 ,  H01L29/78696

    Abstract: Semiconductor devices are provided including an active layer, a gate structure, a spacer, and a source/drain layer. The active layer is on the substrate and includes germanium. The active layer includes a first region having a first germanium concentration, and a second region on both sides of the first region. The second region has a top surface getting higher from a first portion of the second region adjacent to the first region toward a second portion of the second region far from the first region, and has a second germanium concentration less than the first germanium concentration. The gate structure is formed on the first region of the active layer. The spacer is formed on the second region of the active layer, and contacts a sidewall of the gate structure. The source/drain layer is adjacent to the second region of the active layer.

    Abstract translation: 提供了包括有源层，栅极结构，间隔物和源极/漏极层的半导体器件。 有源层在基底上，包括锗。 有源层包括具有第一锗浓度的第一区域和位于第一区域两侧的第二区域。 第二区域具有从与第一区域相邻的第二区域的第一部分朝向远离第一区域的第二区域的第二部分更高的顶表面，并且具有小于第一锗浓度的第二锗浓度。 栅极结构形成在有源层的第一区域上。 间隔物形成在有源层的第二区域上，并与门结构的侧壁接触。 源极/漏极层与有源层的第二区域相邻。

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