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    Nanoscale particles having an iron oxide-containing core enveloped by at least two shells
    13.
    发明授权
    Nanoscale particles having an iron oxide-containing core enveloped by at least two shells 失效
    具有包含至少两个壳的含氧化铁芯的纳米级颗粒

    公开(公告)号：US06979466B2

    公开(公告)日：2005-12-27

    申请号：US10391356

    申请日：2003-03-17

    Applicant: Christoph Lesniak ,  Thomas Schiestel ,  Helmut Schmidt ,  Andreas Jordan

    Inventor： Christoph Lesniak ,  Thomas Schiestel ,  Helmut Schmidt ,  Andreas Jordan

    IPC: A61K9/16 ,  A61K41/00 ,  A61P35/00 ,  A61K9/51

    CPC classification number: A61K41/0052

    Abstract: The invention relates to nanoscale particles suited especially for use in tumor therapy by hyperthermia. Said particles comprise a (preferably superparamagnetic) iron oxide-containing core and at least two shells surrounding said core. The (innermost) shell adjoining the core is an envelope which comprises groups capable of forming cationic groups and is broken down by human or animal tissue at such a slow rate as to allow for association of the core surrounded by said envelope with the surface of cells and/or for absorption of said core into the inside of cells. The outer shell(s) consist(s) of species having neutral and/or anionic groups which allow the nanoscale particles to appear to the outside as having a neutral or negative charge and which are broken down by human or animal tissue more rapidly than the innermost shell—and in so doing uncover the shells underneath—but still sufficiently slowly so as to ensure that the nanoscale particles are adequately distributed in a tissue infiltrated with same particles in a particular point.

    Abstract translation: 本发明涉及特别适用于通过高热治疗肿瘤治疗的纳米级颗粒。 所述颗粒包含（优选超顺磁性）含氧化铁的芯和围绕所述芯的至少两个壳。 与核心相邻的（最内侧）壳是包含能够形成阳离子基团并且以如此慢的速率被人或动物组织分解以允许由所述包膜包围的核与细胞表面缔合的基团 和/或用于将所述核吸收到细胞内部。 外壳由具有中性和/或阴离子基团的物质组成，其允许纳米级颗粒以外面的形式出现在外部，具有中性或负电荷，并且比人或动物组织更快地分解 最内层的壳体，并且在其中露出壳下面，但是仍然足够缓慢，以便确保纳米级颗粒在特定的点上适当地分布在渗透有相同颗粒的组织中。

    Corner key for connecting profiles together and frame work assembly
    14.
    发明申请
    Corner key for connecting profiles together and frame work assembly 审中-公开
    用于将轮廓连接在一起和框架工作组件的角键

    公开(公告)号：US20050115178A1

    公开(公告)日：2005-06-02

    申请号：US10501460

    申请日：2002-01-14

    Applicant: Helmut Schmidt

    Inventor： Helmut Schmidt

    IPC: E06B3/96 ,  E06B3/964 ,  E04B1/00

    CPC classification number: E06B3/9641 ,  E06B3/9616 ,  E06B3/9636

    Abstract: A corner key (10) for connecting profiles (12, 14) together and a frame work assembly formed of such corner keys (10) and (profiles (12, 14). Each profile (12, 14) has an anchoring channel (16, 18), a drainage and venting passage (20, 22) and a securing bore (24, 26). The corner key (10) has two adjacent inner corner faces (28, 30), two adjacent outer corner faces (32, 34), and opposite inner and outer side corner faces (36, 38). Tabs (40, 42) on the inner corner faces (28, 30) guide the coupling of the profiles (12, 14). Fasteners (48, 50) are inserted through the outer corner faces (32, 34) in corner key bores (44, 46) and in the bores (24, 26) of the profiles (12, 14). A drainage and venting passage (52) in the corner key (10) communicates with the drainage and venting passages (20, 22) of the profiles (12, 14).

    Abstract translation: 用于将轮廓（12,14）连接在一起的角键（10）和由这些角键（10）和（轮廓（12,14））形成的框架工作组件。每个轮廓（12,14）具有锚定通道 ，18），排水和排气通道（20,22）和固定孔（24,26），角键（10）具有两个相邻的内角面（28,30），两个相邻的外角面（32， 内侧角面（28,30）上的突片（40,42）引导型材（12,14）的连接，紧固件（48,50） ）通过角形键孔（44,46）中的外角面（32,34）和型材（12,14）的孔（24,26）中插入，排水通道（52） 角键（10）与轮廓（12,14）的排水通道（20,22）连通。

    Nanocomposite material for the production of index of refraction gradient films
    15.
    发明申请
    Nanocomposite material for the production of index of refraction gradient films 有权
    用于生产折射率梯度膜的纳米复合材料

    公开(公告)号：US20050101698A1

    公开(公告)日：2005-05-12

    申请号：US10500194

    申请日：2003-01-03

    Applicant: Takamasa Harada ,  Fumio Kita ,  Andreas Zimmermann ,  Ulrike Dellwo ,  Martin Mennig ,  Peter Oliveira ,  Helmut Schmidt ,  Heike Schneider

    Inventor： Takamasa Harada ,  Fumio Kita ,  Andreas Zimmermann ,  Ulrike Dellwo ,  Martin Mennig ,  Peter Oliveira ,  Helmut Schmidt ,  Heike Schneider

    IPC: G03H1/02 ,  B32B27/18 ,  C08J7/04 ,  C08K3/00 ,  C08K9/04 ,  C08L83/04 ,  C08L101/00 ,  C09D4/02 ,  C09D7/12 ,  C09D163/00 ,  C09D183/06 ,  C09D183/07 ,  C09D201/00 ,  G02B1/04 ,  G02B3/00 ,  C08K9/10

    CPC classification number: C08L83/06 ,  C08K3/013 ,  C09D183/06 ,  G02B1/04 ,  G03H2260/12 ,  C08L2666/04

    Abstract: The invention relates to solid or gel-type nanocomposite material which can be polymerised, containing a) 4.9 95.9 wt. % of a soluble polymer; b) 4-95 wt. % of a partially or totally condensed silane selected from the group of epoxyalkoxysilanes, alkoxysilanes and alkylalkoxysilanes, the silane having an inorganic condensation degree of between 33-100% and an organic conversion degree of between 0-95%; c) 0-60 wt. % of an acrylate; d) 0.1-50 wt. % of surface modified nanometric particles selected from the group of oxides, sulphides, selenides, tellurides, halogenides, carbides, arsenides, antimonides, nitrides, phosphides, carbonates, carboxylates, phosphates, sulphates, silicates, titanates, zirconates, aluminates, stannates, plumbates and a mixed oxides; e) 0-50 wt.-% of a plasticiser, f) 0-5 wt. % of a thermal or photochemical cross-linking initiator, sensitizer, auxiliary wetting agent, adhesive agent, antioxidant, stabiliser, colouring agent, photochrome material and thermochrome material in relation to the total weight (dry weight) of the nanocomposite material.

    Abstract translation: 本发明涉及可以聚合的固体或凝胶型纳米复合材料，其包含a）4.9 95.9wt。 ％的可溶性聚合物; b）4-95wt。 选自环氧烷氧基硅烷，烷氧基硅烷和烷基烷氧基硅烷的部分或全部冷凝的硅烷的％，硅烷的无机缩合度在33-100％之间，有机转化度在0-95％之间; c）0-60wt。 ％的丙烯酸酯; d）0.1-50wt。 选自氧化物，硫化物，硒化物，碲化物，卤化物，碳化物，砷化物，锑化物，氮化物，磷化物，碳酸盐，羧酸盐，磷酸盐，硫酸盐，硅酸盐，钛酸盐，锆酸盐，铝酸盐，锡酸盐，铅酸铅的表面改性纳米颗粒的％ 和混合氧化物; e）0-50重量％的增塑剂，f）0-5重量％ 相对于纳米复合材料的总重量（干重），热或光化学交联引发剂，敏化剂，辅助润湿剂，粘合剂，抗氧化剂，稳定剂，着色剂，感光材料和热变色材料的％。

    Coating composition, based on organically modified inorganic condensates
    17.
    发明授权
    Coating composition, based on organically modified inorganic condensates 失效
    涂料组合物，基于有机改性无机缩合物

    公开(公告)号：US06790532B1

    公开(公告)日：2004-09-14

    申请号：US10111175

    申请日：2002-04-18

    Applicant: Andreas Gier ,  Martin Mennig ,  Helmut Schmidt

    Inventor： Andreas Gier ,  Martin Mennig ,  Helmut Schmidt

    IPC: B32B904

    CPC classification number: C09D183/08 ,  C03C17/30 ,  C09D183/14 ,  Y10T428/31663

    Abstract: A coating composition comprises a polycondensate obtained by reacting a prehydrolysate based on at least on epoxide-containing hydrolysable silane; at least one amine component selected from a prehydrolysate based on at least one amino-containing hydrolysable silane and an amine compound containing at least two amino groups; and an amino group protective reagent. The coating composition is particulary suitable for coating glass, glass ceramic, ceramic, and plastic, and permits an increase in strength and protection against damage.

    Abstract translation: 涂料组合物包含通过基于至少含有环氧化物的可水解硅烷使预水解产物反应获得的缩聚物; 至少一种胺组分，其选自基于至少一种含氨基的可水解硅烷的预水解产物和含有至少两个氨基的胺化合物; 和氨基保护试剂。 涂料组合物特别适用于涂覆玻璃，玻璃陶瓷，陶瓷和塑料，并且允许增加强度和防止损坏。

    Nanostructured forms and layers and method for producing them using stable water-soluble precursors
    19.
    发明授权
    Nanostructured forms and layers and method for producing them using stable water-soluble precursors 有权
    纳米结构形式和层以及使用稳定的水溶性前体制备它们的方法

    公开(公告)号：US06620514B1

    公开(公告)日：2003-09-16

    申请号：US09647971

    申请日：2000-10-06

    Applicant: Ertugrul Arpac ,  Gerhard Jonschker ,  Hermann Schirra ,  Helmut Schmidt

    Inventor： Ertugrul Arpac ,  Gerhard Jonschker ,  Hermann Schirra ,  Helmut Schmidt

    IPC: B32B904

    CPC classification number: C09D4/00 ,  C03C1/008 ,  C03C14/00 ,  C03C17/009 ,  C03C2214/12 ,  C09D183/04 ,  Y10T428/2995 ,  Y10T428/31663 ,  C08G77/04 ,  C08G77/00 ,  C08L2666/54

    Abstract: A process for preparing a composition for producing nanostructured mouldings and layers comprises contacting an aqueous and/or alcoholic sol of a compound of an element selected from silicon sand metals of the main groups and transition groups of the Periodic Table with species possessing hydrolysable alkoxy groups and comprising at least one organically modified alkoxysilane or a precondensate derived therefrom, under conditions which lead to (further) hydrolysis of the species, and subsequent removal of the alcohol formed and any alcohol already present originally. The process is characterized in that the alcohol is removed in an amount such that the residual alcohol content of the composition is not more than 20% by weight.

    Abstract translation: 制备纳米结构模制品和层的组合物的方法包括使选自主体的硅砂金属和周期表的过渡基团的元素的化合物的水溶液和/或醇溶胶与具有可水解烷氧基的物质接触， 包括至少一种有机改性的烷氧基硅烷或由其衍生的预缩合物，在导致（进一步）水解该物质的条件下，随后除去所形成的醇和任何已经存在的醇。 该方法的特征在于，以使得组合物的残余醇含量不超过20重量％的量除去醇。

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