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34 条记录 (耗时 0.054 秒)

    CRYSTAL POLYMORPH OF HYDROXYNOREPHEDRIN DERIVATIVE HYDROCHLORIDE
    11.
    发明申请
    CRYSTAL POLYMORPH OF HYDROXYNOREPHEDRIN DERIVATIVE HYDROCHLORIDE 失效
    羟基吗啡衍生化氢氯化物的晶体聚合物

    公开(公告)号：US20090069421A1

    公开(公告)日：2009-03-12

    申请号：US11912407

    申请日：2006-04-24

    申请人： Kiyoshi Kasai ,  Michio Toda

    发明人： Kiyoshi Kasai ,  Michio Toda

    IPC分类号： A61K31/216 ,  C07C229/34 ,  A61P13/00

    CPC分类号： C07C217/60

    摘要： The present invention provides a novel crystal polymorph of ethyl (−)-2-[4-[2-[[1S,2R]-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-2,5-dimethylphenoxyacetate hydrochloride which can be determined by characteristic diffraction peaks of the powder X-ray diffraction or the like, and obtained from ethyl (−)-2-[4-[2-[[1S,2R]-2-hydroxy-2-(4-hydroxyphenyl)-1-methylethyl]amino]ethyl]-2,5-dimethylphenoxyacetate by a specific method.

    摘要翻译： 本发明提供了（ - ） - 2- [4- [2 - [[1S，2R] -2-羟基-2-（4-羟基苯基）-1-甲基乙基]氨基]乙基] 可以通过粉末X射线衍射等的特征衍射峰确定，并由（ - ） - 2- [4- [2 - [[1S，2R] -2- 羟基-2-（4-羟基苯基）-1-甲基乙基]氨基]乙基] -2,5-二甲基苯氧基乙酸酯。

    Magnetic carrier, preparation thereof, and method of extraction of nucleic acid
    13.
    发明授权
    Magnetic carrier, preparation thereof, and method of extraction of nucleic acid 失效
    磁性载体，其制备方法和提取核酸的方法

    公开(公告)号：US06503762B1

    公开(公告)日：2003-01-07

    申请号：US09702758

    申请日：2000-11-01

    申请人： Syoichi Yamauchi ,  Kiyoshi Kasai

    发明人： Syoichi Yamauchi ,  Kiyoshi Kasai

    IPC分类号： G01N33553

    CPC分类号： B01J20/28016 ,  B01J20/103 ,  B01J20/28004 ,  B01J20/28009 ,  B01J20/28057 ,  B01J20/28069 ,  B01J20/28078 ,  B01J20/286 ,  B01J20/3204 ,  B01J20/3257 ,  B01J20/3263 ,  B01J20/327 ,  B01J2220/54 ,  C12Q1/6806 ,  Y10S428/90 ,  Y10T428/2993

    摘要： A novel magnetic carrier is provided which comprises particulate silica containing a magnetic material, having polyacrylamide on the surface thereof in an amount ranging from 0.3 to 5 mmol/g in terms of monomeric acrylamide. A process for producing the magnetic carrier is also provided in which the surface of particulate silica containing a magnetic material is treated with a coupling agent, and the treated particulate silica is reacted with acrylamide and/or polyacrylamide. The magnetic carrier is useful for extraction of nucleic acid. The magnetic carrier can be produced readily by controlling the shape, the particle diameter, and the pore diameter, and is excellent in strength and adsorption efficiency. The extraction of a nucleic acid can be automated by use of the magnetic carrier.

    摘要翻译： 提供了一种新的磁性载体，其包含含有磁性材料的颗粒状二氧化硅，其表面上的聚丙烯酰胺的量为单体丙烯酰胺换算为0.3-5mmol / g。 还提供一种制备磁性载体的方法，其中用偶联剂处理含有磁性材料的颗粒状二氧化硅的表面，并将经处理的颗粒状二氧化硅与丙烯酰胺和/或聚丙烯酰胺反应。 磁性载体可用于提取核酸。 通过控制形状，粒径和孔径可以容易地制造磁性载体，并且强度和吸附效率优异。 可以通过使用磁性载体自动提取核酸。

    Magnetic polymer particle and process for manufacturing the same
    14.
    发明授权
    Magnetic polymer particle and process for manufacturing the same 失效
    磁性聚合物颗粒及其制造方法

    公开(公告)号：US5814687A

    公开(公告)日：1998-09-29

    申请号：US791745

    申请日：1997-01-30

    申请人： Kiyoshi Kasai ,  Masayuki Hattori ,  Kakun Han

    发明人： Kiyoshi Kasai ,  Masayuki Hattori ,  Kakun Han

    IPC分类号： A61K47/30 ,  C08F2/44 ,  C08K3/22 ,  C08L31/02 ,  C08L31/04 ,  C08L33/04 ,  C08L33/14 ,  H01F1/44 ,  C08K7/16

    CPC分类号： H01F1/445 ,  C08K3/22 ,  C08K2003/2268 ,  C08K2003/2272 ,  C08K2003/2275

    摘要： Novel magnetic polymer particles which resists precipitation in an aqueous medium. The novel magnetic polymer particles can be widely used as carriers for diagnostics and immobilized enzymes, carriers for bacterial isolation, carriers for cell segregation, carriers for isolation and purification of ribonucleic acids and proteins, carriers for drug deliveries, and are usable as material for magnetic toners, magnetic inks, and magnetic coatings. The process for manufacturing the magnetic polymer particles comprising; dispersing a monomer mixture including a hydrophobic monomer containing more than 50% by weight of (meth)acrylic ester and a superparamagnetic substance in an aqueous medium to prepare an suspension, and polymerizing the monomers.

    摘要翻译： 抗水性介质中的沉淀的新型磁性聚合物颗粒。 新型磁性聚合物颗粒可广泛用作诊断和固定化酶的载体，用于细菌分离的载体，用于细胞分离的载体，用于分离和纯化核糖核酸和蛋白质的载体，用于药物递送的载体，并且可用作磁性材料 调色剂，磁性油墨和磁性涂料。 制造磁性聚合物颗粒的方法包括： 将包含超过50重量％的（甲基）丙烯酸酯和超顺磁性物质的疏水性单体的单体混合物在水性介质中分散以制备悬浮液，并使单体聚合。

    Process for preparing polymer particles
    15.
    发明授权
    Process for preparing polymer particles 失效
    制备聚合物颗粒的方法

    公开(公告)号：US5189107A

    公开(公告)日：1993-02-23

    申请号：US489215

    申请日：1990-03-06

    申请人： Kiyoshi Kasai ,  Fujio Sakurai ,  Hiroshi Tadenuma

    发明人： Kiyoshi Kasai ,  Fujio Sakurai ,  Hiroshi Tadenuma

    IPC分类号： C08F2/18 ,  C08F2/00 ,  C08F2/22 ,  C08F2/24 ,  C08F2/44 ,  C08F291/00

    CPC分类号： C08F291/00 ,  Y10S525/902

    摘要： Polymer particles prepared by polymerizing polymerizable monomers by seed polymerization, with far more excellent polymerization stability than conventional seed polymerization processes, in the presence of a polymer emulsion comprising low molecular weight polymer particles, radically polymerizable in an aqueous system. The polymer particles are present in an amount of 0.5-30 parts by weight (on solid basis) per 100 parts by weight of polymerizable monomers, have a weight average molecular weight of 500-10,000 and are prepared by emulsion polymerization or soap-free polymerization. The seed polymerization is carried out by initially charging less than 30% by weight of said polymerizable monomers to the polymerization mixture, and after the polymerization conditions are established, by continuously or intermittently adding the remaining portion of said polymerizable monomers to the reaction system.

    摘要翻译： 在聚合物乳液存在下，通过在聚合反应中聚合可聚合单体而制备的聚合物颗粒，其聚合稳定性比常规种子聚合方法具有更好的聚合稳定性，该聚合物乳液包含在水性体系中可自由基聚合的低分子量聚合物颗粒。 聚合物颗粒的存在量为每100重量份可聚合单体0.5-30重量份（基于固体），重均分子量为500-10,000，并通过乳液聚合或无皂聚合制备 。 通过首先将少于30重量％的所述可聚合单体加入到聚合混合物中进行种子聚合，并且在聚合条件建立之后，通过将剩余部分的所述可聚合单体连续或间歇地加入到反应体系中来进行。

    Actuator
    16.
    发明授权
    Actuator 失效
    执行器

    公开(公告)号：US4862029A

    公开(公告)日：1989-08-29

    申请号：US145861

    申请日：1988-01-20

    申请人： Kiyoshi Kasai ,  Naomichi Sakai ,  Tomoyuki Oikawa ,  Kenji Uchino ,  Takaaki Tsukidate ,  Hiroshi Asakura ,  Hiroshi Yamamura ,  Hiroya Nagata

    发明人： Kiyoshi Kasai ,  Naomichi Sakai ,  Tomoyuki Oikawa ,  Kenji Uchino ,  Takaaki Tsukidate ,  Hiroshi Asakura ,  Hiroshi Yamamura ,  Hiroya Nagata

    IPC分类号： C04B35/465 ,  C04B35/486 ,  C04B35/491 ,  H01L41/187

    CPC分类号： C04B35/465 ,  C04B35/486 ,  C04B35/491 ,  H01L41/094 ,  H01L41/1876

    摘要： An actuator of the present invention is composed of a monomorph-type piezoelectric ceramic. The monomorph-type piezoelectric ceramic is a BaTiO.sub.3 -based ceramic, a PZT based ceramic having Nb, Sb, La, Mn, Nd and Bi, BaTiO.sub.3 --SrTiO.sub.3 -based ceramic containing SrTiO.sub.3 by 20 to 35 mole %, K(Nb, Ta)O.sub.3 -based ceramic, or a ceramic represented by a general formula: [Pb, (A.sub.1/2 B.sub.1/2)](Zr.sub.1-n, Cn)O.sub.3 where A is a monovalent element such as Li, Na, K, Rb, Cs or the like, B is a trivalent element such as Bi, La, Y, Sb, Ga or the like, A and B being both replaceable solid-meltable elements for Pb, C is an element such as Ti, Sn or the like that is a replaceable solid-meltable element for Zr, and n is from 0 to 0.8.

    摘要翻译： 本发明的致动器由单晶型压电陶瓷构成。 单晶型压电陶瓷是一种BaTiO3系陶瓷，具有Nb，Sb，La，Mn，Nd和Bi，BaTiO3-SrTiO3系陶瓷的PZT系陶瓷，含有20〜35摩尔％的SrTiO 3，K（Nb，Ta ）或由通式[Pb，（A1 / 2B1 / 2）]（Zr1-n，Cn）O3表示的陶瓷，其中A是Li，Na，K，Rb等的一价元素， Cs等，B是Bi，La，Y，Sb，Ga等的三价元素，A和B都是Pb的可固态可固化元素，C是Ti，Sn等元素 其是用于Zr的可替换的固体可熔性元素，n为0至0.8。

    Process for preparing high-purity .alpha.-type silicon nitride
    17.
    发明授权
    Process for preparing high-purity .alpha.-type silicon nitride 失效
    制备高纯度α型氮化硅的方法

    公开(公告)号：US4346068A

    公开(公告)日：1982-08-24

    申请号：US222671

    申请日：1981-01-05

    申请人： Kiyoshi Kasai ,  Yoshitaka Kubota ,  Takaaki Tsukidate

    发明人： Kiyoshi Kasai ,  Yoshitaka Kubota ,  Takaaki Tsukidate

    IPC分类号： C01B21/068

    CPC分类号： C01B21/068 ,  C01P2002/72 ,  C01P2004/03 ,  C01P2004/61

    摘要： High-purity .alpha.-type silicon nitride comprised of a granular crystal having an .alpha.-phase content of at least 95%, a nitrogen content of at least 38% by weight and an average particle size of not larger than 3 .mu.m is provided. This high-purity .alpha.-type silicon nitride is prepared by heating a nitrogen-containing silane compound at a temperature of at least about 1,300.degree. C. in a heating furnace comprised of a material containing a metal having a melting point exceeding 1,600.degree. C. and capable of being bonded with oxygen at the heating temperature.

    摘要翻译： 提供了由具有至少95％的α-相含量，至少38重量％的氮含量和不大于3μm的平均粒径的粒状晶体构成的高纯度α型氮化硅。 这种高纯度α型氮化硅通过在包含熔点超过1600℃的金属的加热炉中在至少约1300℃的温度下加热含氮硅烷化合物来制备。 并且能够在加热温度下与氧结合。