Coating solution for glucose sensing membrane and method of manufacturing optical glucose sensor chip
    11.
    发明授权
    Coating solution for glucose sensing membrane and method of manufacturing optical glucose sensor chip 有权
    用于葡萄糖感测膜的涂层溶液和制造光学葡萄糖传感器芯片的方法

    公开(公告)号:US07651864B2

    公开(公告)日:2010-01-26

    申请号:US11283861

    申请日:2005-11-22

    CPC分类号: G01N33/523 C12Q1/54 G01N31/22

    摘要: A method of preparing a coating solution for a glucose sensing membrane, the method comprising preserving a first solution containing an oxidizing enzyme or a reducing enzyme of glucose and a reagent for generating a substance for coloring a coloring agent dissolved in a buffer solution, preserving a second solution containing a mixed solution of an alcohol solution of the coloring agent and a solution of a membrane-forming polymer compound, and mixing the first solution and the second solution.

    摘要翻译: 一种制备葡萄糖感测膜的涂布溶液的方法,所述方法包括保存含有葡萄糖的氧化酶或还原酶的第一溶液和用于产生溶解在缓冲溶液中的着色剂着色物质的试剂,保存 第二溶液,其含有着色剂的醇溶液和成膜高分子化合物的溶液的混合溶液,并混合第一溶液和第二溶液。

    Method for Measuring Sample, Package for Sensor Chips, and Mechanism for Fixing Sensor Chips
    14.
    发明申请
    Method for Measuring Sample, Package for Sensor Chips, and Mechanism for Fixing Sensor Chips 审中-公开
    用于测量样品,传感器芯片封装的方法和用于固定传感器芯片的机构

    公开(公告)号:US20090064802A1

    公开(公告)日:2009-03-12

    申请号:US12206032

    申请日:2008-09-08

    IPC分类号: G01N33/00 H01L29/00 B23P19/00

    CPC分类号: G01N33/5438 Y10T29/53178

    摘要: A method for measuring samples includes fitting and mounting, onto a transfer stage, a chip pallet for transporting sensor chips; fitting a positioning hole of a chip package onto a positioning pin; pulling a bottom plate of the chip package off the chip package, so as to simultaneously transfer the housed sensor chips onto the transfer stage; pulling upward the chip pallet so as to simultaneously transfer, onto the chip pallet, the sensor chips on the transfer stage; and mounting the chip pallet having the sensor chips mounted thereon onto a measuring device, and measuring samples.

    摘要翻译: 一种用于测量样品的方法包括:在传送台上安装和安装用于传送传感器芯片的芯片托盘; 将芯片封装的定位孔装配到定位销上; 将芯片封装的底板从芯片封装中拉出,以便将所容纳的传感器芯片同时传送到转移台上; 将芯片托盘向上拉,以便同时将转印台上的传感器芯片转移到芯片托盘上; 并将安装有传感器芯片的芯片托盘安装在测量装置上,并测量样品。

    TEST ELEMENT, TEST KIT, TEST DEVICE, AND TEST METHOD
    15.
    发明申请
    TEST ELEMENT, TEST KIT, TEST DEVICE, AND TEST METHOD 审中-公开
    测试元件,测试套件,测试设备和测试方法

    公开(公告)号:US20120064559A1

    公开(公告)日:2012-03-15

    申请号:US13207690

    申请日:2011-08-11

    IPC分类号: C12Q1/28 C12Q1/26 C12M1/34

    摘要: According to one embodiment, a test element includes a base, a pair of optical element units, an optical waveguide unit, a detection unit and a holding unit. The base has transparency. The pair of optical element units are arranged away from each other on a major surface of the base. The optical waveguide unit is provided on the major surface of the base. The detection unit is provided on a major surface of the optical waveguide unit of between the optical element units. The major surface of the optical waveguide unit is an opposite side which touches the base. The holding unit is in a frame shape, and one end of the holding unit being is provided to protrude from a major surface of the detection unit. The detection unit includes a color former and a film-formed body holding the color former.

    摘要翻译: 根据一个实施例,测试元件包括基座,一对光学元件单元,光波导单元,检测单元和保持单元。 基地有透明度。 一对光学元件单元在基座的主表面上彼此远离布置。 光波导单元设置在基座的主表面上。 检测单元设置在光学元件单元之间的光波导单元的主表面上。 光波导单元的主表面是与基座接触的相对侧。 保持单元是框架形状,并且保持单元的一端设置成从检测单元的主表面突出。 检测单元包括着色剂和保持着色剂的成膜体。

    Optical waveguide type antibody chip and method of measuring antigen concentration
    16.
    发明授权
    Optical waveguide type antibody chip and method of measuring antigen concentration 有权
    光波导型抗体芯片及抗原浓度测定方法

    公开(公告)号:US07829327B2

    公开(公告)日:2010-11-09

    申请号:US12047670

    申请日:2008-03-13

    IPC分类号: G01N33/551 G01N33/552

    摘要: An optical waveguide type antibody chip includes a transparent substrate, an incident-side optical element and an emitting-side optical element placed at a distance from each other on a primary face of the substrate, a water repellent resin film formed on the primary face of the substrate including an optical waveguide layer formed between the optical elements, the water repellent resin film includes a reaction hole having exposed the optical waveguide layer on its bottom and a frame-shaped trench surrounding the reaction hole, a rectangular frame-shaped cell wall which is fixed in the trench of the water repellent resin film and which forms a cell capable of infusion and discharge of a specimen solution together with the reaction hole, and an antibody immobilization layer formed on the bottom of the reaction hole, the surface of the antibody immobilization layer being masked with at least a buffer agent and a salt.

    摘要翻译: 光波导型抗体芯片包括在基板的主面上彼此相隔一定距离放置的透明基板,入射侧光学元件和发光侧光学元件,形成在基板的主面上的防水树脂膜 所述基板包括形成在所述光学元件之间的光波导层,所述防水树脂膜包括在其底部露出光波导层的反应孔和围绕所述反应孔的框状沟槽,矩形框状电池壁, 固定在防水树脂膜的沟槽中,并且形成能够与反应孔一起输注和排出样品溶液的电池,以及形成在反应孔底部的抗体固定层,抗体表面 固定层用至少缓冲剂和盐掩蔽。

    ANTIBODY CHIP, ANTIGEN MEASURING APPARATUS AND LIQUID DISCHARGING METHOD
    17.
    发明申请
    ANTIBODY CHIP, ANTIGEN MEASURING APPARATUS AND LIQUID DISCHARGING METHOD 审中-公开
    抗体芯片,抗原测量装置和液体排出方法

    公开(公告)号:US20070218545A1

    公开(公告)日:2007-09-20

    申请号:US11566857

    申请日:2006-12-05

    IPC分类号: C12M1/34

    摘要: It is an object to provide an antibody chip and a light source measuring apparatus which are excellent in a reproducibility and a workability of a measurement and can easily be utilized. A light source measuring apparatus (1) includes, as a main structure, a concentration measuring device (2), an antibody chip (3) and a cell washing device (4). The concentration measuring device (2) serves to measure a concentration of an antigen in a specimen solution taken by the antibody chip (3) The cell washing device (4) has solution injecting means constituted by an injecting pump (44), an injecting tube (45), a first solution vessel (46), a second solution vessel (47) and a solution selecting valve (48) and solution discharging means constituted by a plurality of discharging pumps (51), a discharging tube (52), an intake end (52a) and the like. In a state in which a container cover (8) is opened, an inner part of a cell (39) of the antibody chip (3) having an antibody fixing layer formed on a main surface of a substrate (37) on a chip carrier (7) is washed to stabilize the antibody fixing layer without the solution remaining in the cell.

    摘要翻译: 本发明的目的是提供一种测量重现性和可加工性优异的抗体芯片和光源测量装置,并且可以容易地利用。 作为主要结构的光源测量装置(1)包括浓度测定装置(2),抗体芯片(3)和细胞清洗装置(4)。 浓度测定装置(2)用于测定由抗体芯片(3)取出的试样溶液中的抗原浓度。细胞洗涤装置(4)具有由注射泵(44),注射管 (45),第一溶液容器(46),第二溶液容器(47)和溶液选择阀(48)以及由多个排出泵(51),排放管(52),排出管 进气端(52a)等。 在容器盖(8)打开的状态下,具有抗体固定层的抗体芯片(3)的电池(39)的内部部分形成在芯片载体上的基板(37)的主表面上 (7)洗涤以稳定抗体固定层,而不将溶液保留在细胞中。

    OPTICAL SENSOR
    18.
    发明申请
    OPTICAL SENSOR 审中-公开
    光传感器

    公开(公告)号:US20110236266A1

    公开(公告)日:2011-09-29

    申请号:US13039748

    申请日:2011-03-03

    IPC分类号: G01N21/00 G01N1/10

    摘要: According to one embodiment, an optical sensor includes an optical waveguide module and a specimen area. The specimen area is provided adjacent to the optical waveguide module, and is configured to hold a specimen. The specimen area includes a sensing area and a precipitation area. An optical change occurs in the sensing area. A precipitate of the specimen is precipitated in the precipitation area. The precipitation area is placed at a different position from a position of the sensing area which is attached to the optical waveguide module.

    摘要翻译: 根据一个实施例,光学传感器包括光波导模块和样本区域。 样本区域设置在光波导模块的附近,并且被配置为保持样本。 样本区域包括感测区域和降水区域。 在感应区域发生光学变化。 样品沉淀物沉淀在沉淀区域。 降水区域位于与附接到光波导模块的感测区域的位置不同的位置。

    OPTICAL WAVEGUIDE TYPE ANTIBODY CHIP AND METHOD OF MEASURING ANTIGEN CONCENTRATION
    19.
    发明申请
    OPTICAL WAVEGUIDE TYPE ANTIBODY CHIP AND METHOD OF MEASURING ANTIGEN CONCENTRATION 有权
    光波导型抗体芯片和测量抗原浓度的方法

    公开(公告)号:US20080227126A1

    公开(公告)日:2008-09-18

    申请号:US12047670

    申请日:2008-03-13

    IPC分类号: G01N33/543

    摘要: An optical waveguide type antibody chip includes a transparent substrate, an incident-side optical element and an emitting-side optical element placed at a distance from each other on a primary face of the substrate, a water repellent resin film formed on the primary face of the substrate including an optical waveguide layer formed between the optical elements, the water repellent resin film includes a reaction hole having exposed the optical waveguide layer on its bottom and a frame-shaped trench surrounding the reaction hole, a rectangular frame-shaped cell wall which is fixed in the trench of the water repellent resin film and which forms a cell capable of infusion and discharge of a specimen solution together with the reaction hole, and an antibody immobilization layer formed on the bottom of the reaction hole, the surface of the antibody immobilization layer being masked with at least a buffer agent and a salt.

    摘要翻译: 光波导型抗体芯片包括在基板的主面上彼此相隔一定距离放置的透明基板,入射侧光学元件和发光侧光学元件,形成在基板的主面上的防水树脂膜 所述基板包括形成在所述光学元件之间的光波导层,所述防水树脂膜包括在其底部露出光波导层的反应孔和围绕所述反应孔的框状沟槽,矩形框状电池壁, 固定在防水树脂膜的沟槽中,并且形成能够与反应孔一起输注和排出样品溶液的电池,以及形成在反应孔底部的抗体固定层,抗体表面 固定层用至少缓冲剂和盐掩蔽。

    Oxygen-enriched air producing device and oxygen-enriched air producing method
    20.
    发明授权
    Oxygen-enriched air producing device and oxygen-enriched air producing method 有权
    富氧空气生产装置和富氧空气生产方法

    公开(公告)号:US09254493B2

    公开(公告)日:2016-02-09

    申请号:US14003700

    申请日:2012-05-08

    摘要: The invention is characterized in: forming a magnetic field inside a flow channel tube, the tube wall of which is formed from a material that is nonmagnetic and which, when the pressure outside the flow channel tube is lower than the pressure inside the flow channel tube, passes a portion of the air flowing inside the tube through the tube wall and discharges same to the outside thereof; supplying air to the flow channel tube so that at least a region of laminar flow is formed inside the flow channel tube; and reducing the pressure outside the flow channel tube to a prescribed pressure.

    摘要翻译: 本发明的特征在于:在流道管内形成磁场,其管壁由非磁性的材料形成,当流道管外部的压力低于流道管内的压力时 使流过管内的空气的一部分通过管壁,并将其排出到其外部; 向所述流路管供给空气,使得在所述流路管内形成至少一层层流区域; 并将流道管外的压力降低到规定的压力。