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公开(公告)号：US20180005523A1
公开(公告)日：2018-01-04
申请号：US15196142
申请日：2016-06-29
IPC分类号： G08G1/0965 , G08G1/095 , G01C21/34 , G01C21/36 , G08G1/0968 , G08G1/0967
CPC分类号： G08G1/0965 , G01C21/3415 , G01C21/3691 , G01C21/3697 , G08G1/087 , G08G1/095 , G08G1/096716 , G08G1/096741 , G08G1/096775 , G08G1/096791 , G08G1/0968
摘要： An emergency vehicle route management method, system, and non-transitory computer readable medium, include analyzing a map to plot roads, a user including user data, and an emergency vehicle including emergency vehicle data on the map, determining an intersection of the roads within a predetermined radius of the emergency vehicle, and delivering an action for the user based on a road on a path of the emergency vehicle being determined by the determining to intersect with a road of the user.
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公开(公告)号：US20170224279A1
公开(公告)日：2017-08-10
申请号：US15018218
申请日：2016-02-08
IPC分类号： A61B5/00 , A61F2/07 , A61F2/24 , A61B8/06 , A61B7/04 , A61B5/07 , A61B8/04 , A61B8/02 , A61B5/0402 , A61F2/82 , A61B8/08
CPC分类号： A61B5/686 , A61B5/0022 , A61B5/026 , A61B5/0285 , A61B5/0402 , A61B5/076 , A61B5/6862 , A61B7/045 , A61B8/02 , A61B8/04 , A61B8/06 , A61B8/065 , A61B8/12 , A61B8/42 , A61B8/4444 , A61B8/4472 , A61B8/488 , A61B8/5223 , A61B2562/0219 , A61F2/07 , A61F2/24 , A61F2/2403 , A61F2/82
摘要： A system and method for monitoring a health status of a subject. The system comprises: a medical device implantable in the subject and having a passage or compartment through which blood flows through; a sensor device embedded at or near a surface of said passage within said medical device for generating signals suitable for measuring a Doppler shift effect occurring within said passage; and a control device coupled to said sensor device for measuring a liquid blood flow rate within said passage based on sensor generated signals outputs. The embedded sensor device comprises a first piezo-electric element configured to generate an acoustic excitation signal and a second piezo-electric element configured to receive said acoustic excitation signal. The second piezo-electric element emits a signal responsive to said acoustic excitation signal. Control device in real time compares a generated output signal with the input excitation signal to determine a Doppler frequency shift measurement.
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公开(公告)号：US09668991B1
公开(公告)日：2017-06-06
申请号：US14963521
申请日：2015-12-09
发明人： Amos Cahan
CPC分类号： A61K31/19 , A61K9/2846 , A61K9/286 , A61K9/2866 , A61K9/4816 , A61K9/4891
摘要： The present invention is directed to a colonic composition including a core having at least one short chain fatty acid selected from the group consisting of butyrate, acetate and propionate, and combinations thereof, or a pharmaceutically acceptable salt or ester thereof; wherein at least one of acetate or propionate is present in the core; and at least one digestion-resistant layer covering the core, the digestion-resistant layer disintegrating in the colon. The present invention is also directed to methods of treatment using the above composition.
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公开(公告)号：US11560484B2
公开(公告)日：2023-01-24
申请号：US16678076
申请日：2019-11-08
发明人： Amos Cahan , Hariklia Deligianni , Xin Ding , Mareva B. Fevre , James L. Hedrick , Pei-Yun S. Hsueh , Zhen Chang Liang , Nathaniel H. Park , Theodore G. van Kessel , Rudy J. Wojtecki , Yi Yan Yang
IPC分类号： C09D5/14 , A61M5/142 , C09D7/65 , B05D1/36 , C08G73/02 , A61C8/00 , A61F2/30 , B05D5/00 , A01N33/12 , A61B5/00 , A61F2/28 , A61L27/34 , A61L27/54 , A61L29/08 , A61L29/16 , A61M5/14 , A61M27/00 , A61N1/378 , B05D3/00 , C08J3/24 , B05D1/02 , A61F2/07 , A61B1/00 , A61N1/36 , A61B17/56 , A61M25/00 , A61F2/01 , A61F2/48 , A61F2/06 , A61F2/14 , A61F2/24 , A61F2/82 , A61N1/362 , C09D179/02
摘要： Antibacterial coatings and methods of making the antibacterial coatings are described herein. A first branched polyethylenimine (BPEI) layer is formed and a first glyoxal layer is formed on a surface of the BPEI layer. The first BPEI layer and the first glyoxal layer are cured to form a crosslinked BPEI coating. The first BPEI layer can be modified with superhydrophobic moieties, superhydrophilic moieties, or negatively charged moieties to increase the antifouling characteristics of the coating. The first BPEI layer can be modified with contact-killing bactericidal moieties to increase the bactericidal characteristics of the coating.
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公开(公告)号：US11371071B2
公开(公告)日：2022-06-28
申请号：US15671713
申请日：2017-08-08
发明人： Amos Cahan , Guy M. Cohen , Theodore G. van Kessel , Sufi Zafar
IPC分类号： C12Q1/02 , C12Q1/18 , G01N21/59 , G01N27/04 , G01N15/06 , C12M1/12 , C12M1/34 , C12M1/00 , C12M3/00 , C12M1/18
摘要： A structure for culturing cells includes growth medium regions on a surface of the structure. Each of the growth medium regions includes a growth medium surface configured to receive and promote growth in a cell that is being cultured. The structure includes a non-growth medium. The non-growth medium includes a non-growth medium surface configured to receive the cell that is being cultured.
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公开(公告)号：US11332772B2
公开(公告)日：2022-05-17
申请号：US16675347
申请日：2019-11-06
发明人： Amos Cahan , Guy M. Cohen , Theodore G. van Kessel , Sufi Zafar
IPC分类号： C12M1/34 , C12Q1/02 , C12Q1/18 , G01N21/59 , G01N27/04 , G01N15/06 , C12M1/12 , C12M1/00 , C12M3/00 , C12M1/18
摘要： A structure for culturing cells includes growth medium regions on a surface of the structure. Each of the growth medium regions includes a growth medium surface configured to receive and promote growth in a cell that is being cultured. The structure includes a non-growth medium. The non-growth medium includes a non-growth medium surface configured to receive the cell that is being cultured.
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公开(公告)号：US11197956B2
公开(公告)日：2021-12-14
申请号：US16691741
申请日：2019-11-22
发明人： Amos Cahan
摘要： Embodiments include methods and systems for maintaining glucose homeostasis. Systems can include a pump, a first reservoir including a homeostasis agent, an umbilical catheter capable of being advanced in the umbilical vein or in the falciform ligament, and a sensor. Systems can also include a biocompatible coating, a microprocessor in communication with the pump and the sensor, and a power supply. Methods can include implanting a pump and reservoir subcutaneously in a patient, advancing a catheter in the umbilical vein or in the falciform ligament, measuring a blood glucose level, pumping a homeostasis agent, and administering the homeostasis agent to the portal venous system.
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公开(公告)号：US11076246B2
公开(公告)日：2021-07-27
申请号：US16456175
申请日：2019-06-28
发明人： Amos Cahan , Katsuyuki Sakuma
摘要： Embodiments of the present invention are directed to a method of stimulating a cornea. A non-limiting example of the method includes capturing a sound with a microphone. A non-limiting example of the method also includes transducing the sound to an electric signal by a microprocessor. A non-limiting example of the method also includes stimulating a piezo-electric element adjacent to a receptor of the cornea, wherein the piezo-electric element is positioned on an eye lens with an electric signal. A non-limiting example of the method also includes mechanically stimulating a receptor of the cornea with the stimulated piezo-electric element.
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公开(公告)号：US11002614B2
公开(公告)日：2021-05-11
申请号：US16557158
申请日：2019-08-30
发明人： Amos Cahan , Guy M. Cohen , Lior Horesh , Raya Horesh
摘要： Low-cost techniques for sensing ambient temperatures in a container or package using phase change materials are provided. In one aspect, a temperature sensor is provided. The temperature sensor includes: at least one phase change material configured to transition from an amorphous state to a crystalline state upon exposure to temperatures above a predetermined threshold temperature for a given duration. A method of monitoring temperature exposure of a consumer good using the temperature sensor is also provided.
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公开(公告)号：US10973732B2
公开(公告)日：2021-04-13
申请号：US15838393
申请日：2017-12-12
发明人： Amos Cahan , Theodore G. van Kessel
摘要： Embodiments include systems, methods, and products for prevention and treatment of orthostatic hypotension, edema, and nocturia. Aspects include a tubular compression sleeve having an adjustable effective radius. Aspects also include a position sensor. Aspects also include an actuator in communication with the position sensor, wherein the actuator is capable of modifying the effective radius of the tubular compression sleeve.
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