公开(公告)号：US20240279580A1

公开(公告)日：2024-08-22

申请号：US18651331

申请日：2024-04-30

Applicant: Life Technologies Corporation

Inventor： Clinton C. Staheli ,  Nephi D. Jones ,  Michael E. Goodwin

IPC: C12M1/00 ,  B01D5/00 ,  B01D47/05 ,  B01F23/231 ,  B01F23/233 ,  B01F23/237 ,  B01F27/2121 ,  B01F27/88 ,  B01F27/90 ,  B01F27/91 ,  B01F35/10 ,  B01F35/51 ,  B01F35/513 ,  B01F35/90 ,  B01F35/92 ,  B01F101/44 ,  C12M1/02 ,  C12M1/06 ,  C12M1/12 ,  C12N1/10 ,  C12N1/12 ,  C12N1/14 ,  C12N1/20 ,  C12N5/00 ,  C12N5/04 ,  C12N5/10 ,  F28B1/02 ,  F28D21/00 ,  F28F3/12 ,  F28F21/06

CPC classification number: C12M23/14 ,  B01D5/0072 ,  B01D47/05 ,  B01F23/23125 ,  B01F23/233 ,  B01F27/2121 ,  B01F27/88 ,  B01F27/90 ,  B01F27/91 ,  B01F35/146 ,  B01F35/51 ,  B01F35/513 ,  B01F35/92 ,  C12M23/26 ,  C12M23/34 ,  C12M27/02 ,  C12M29/00 ,  C12M29/06 ,  C12M29/24 ,  C12M37/00 ,  C12M41/14 ,  C12M41/18 ,  C12N1/10 ,  C12N1/12 ,  C12N1/14 ,  C12N1/20 ,  C12N5/00 ,  C12N5/04 ,  F28B1/02 ,  F28F3/12 ,  F28F21/06 ,  F28F21/065 ,  B01F23/231151 ,  B01F23/231262 ,  B01F23/23362 ,  B01F23/23761 ,  B01F23/237611 ,  B01F23/237612 ,  B01F23/23762 ,  B01F23/23765 ,  B01F2035/98 ,  B01F2101/44 ,  C12N5/10 ,  F28D2021/0063 ,  F28F2255/02

Abstract: A bag assembly for use with a heat exchanger includes a flexible bag having of one or more sheets of polymeric material, the bag having a first end that bounds a first compartment and an opposing second end that bounds a second compartment, a support structure being disposed between the first compartment and the second compartment so that the first compartment is separated and isolated from the second compartment. A first inlet port, a first outlet port, and a first drain port are coupled with the flexible bag so as to communicate with the first compartment. A second inlet port, a second outlet port, and a second drain port are coupled with the flexible bag so as to communicate with the second compartment.

公开(公告)号：US20240044430A1

公开(公告)日：2024-02-08

申请号：US18485155

申请日：2023-10-11

Applicant: Life Technologies Corporation

Inventor： Ryan S. Beus ,  Brandon R. Burtenshaw ,  Eric Davis ,  Patrick L. Draper ,  Michael E. Goodwin ,  Brandon M. Knudsen ,  Jeremy K. Larsen ,  Kevin R. Pickup

IPC: F16L33/207 ,  F16L33/22 ,  B29C65/00 ,  B29C65/68 ,  B29C65/56 ,  A61M39/12

CPC classification number: F16L33/207 ,  F16L33/227 ,  B29C66/131 ,  B29C66/73753 ,  B29C65/68 ,  B29C65/565 ,  B29C66/1224 ,  A61M39/12 ,  B29C66/7392 ,  B29C66/5344 ,  B29C66/1222 ,  B29C66/12 ,  B29C66/7394 ,  B29C66/30321 ,  B29C66/7315 ,  B29C66/1122 ,  B29L2031/24

Abstract: A coupling assembly includes: a tubular compression collar having a tubular body made of a resiliently flexible polymeric material and having an interior surface and an opposing exterior surface; an end of a tube disposed within a throughway of the compression collar; and a tube fitting disposed within the passageway of the tube. The tube fitting includes: a tubular stem; a flange radially outwardly projecting from an exterior surface of the stem; and an annular barb encircling and radially outwardly projecting from the exterior surface of the stem, the annular barb including a frustoconical outside face that extends along and outwardly slopes away from the stem as the outside face extends toward the flange. The compression collar radially inwardly compresses the tube against the annular barb of the tube fitting so that a liquid tight seal is formed between the tube and the tube fitting.

公开(公告)号：US20230234732A1

公开(公告)日：2023-07-27

申请号：US18189994

申请日：2023-03-24

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael E. Goodwin ,  Jeremy K. Larsen ,  Patrick L. Draper ,  Brandon M. Knudsen

IPC: B65B1/04 ,  B65B3/00 ,  B65B3/02 ,  B65B3/04 ,  B65B51/02 ,  B65B51/22

CPC classification number: B65B1/04 ,  B65B3/003 ,  B65B3/02 ,  B65B3/04 ,  B65B51/02 ,  B65B51/225 ,  A61J1/10

Abstract: A fluid manifold system includes a first manifold having portions of opposing flexible sheets welded together to form a fluid flow path therebetween, a fluid inlet communicating with the fluid flow path. The fluid flow path of the first manifold includes: a primary flow path communicating with the fluid inlet of the first manifold; and a plurality of spaced apart secondary flow paths that branch off of the primary flow path. Each secondary flow path has a first end communicating with the primary flow path and an opposing second end, each secondary flow path having a diameter that is smaller than a diameter of the primary flow path. The fluid manifold system also includes a plurality of tubular connectors with each tubular connector being secured to the first manifold at the second end of a corresponding one of the secondary flow paths.

公开(公告)号：US11492582B2

公开(公告)日：2022-11-08

申请号：US16897925

申请日：2020-06-10

Applicant: Life Technologies Corporation

Inventor： Clinton C. Staheli ,  Nephi D. Jones ,  Michael E. Goodwin

IPC: C12M3/00 ,  B01L3/00 ,  C12M1/00 ,  B01D5/00 ,  C12M1/06 ,  C12M1/12 ,  F28F21/06 ,  B01F23/233 ,  B01F23/231 ,  B01F27/88 ,  B01F27/90 ,  B01F27/91 ,  B01F27/2121 ,  B01F35/51 ,  B01F35/92 ,  B01F35/10 ,  B01F35/513 ,  B01D47/05 ,  C12N1/10 ,  C12N1/12 ,  C12N1/14 ,  C12N1/20 ,  C12N5/00 ,  C12N5/04 ,  C12M1/02 ,  F28B1/02 ,  F28F3/12 ,  C12N5/10 ,  F28D21/00 ,  B01F23/237 ,  B01F35/90 ,  B01F101/44

Abstract: A bag assembly for use with a heat exchanger includes a flexible bag having of one or more sheets of polymeric material, the bag having a first end that bounds a first compartment and an opposing second end that bounds a second compartment, a support structure being disposed between the first compartment and the second compartment so that the first compartment is separated and isolated from the second compartment. A first inlet port, a first outlet port, and a first drain port are coupled with the flexible bag so as to communicate with the first compartment. A second inlet port, a second outlet port, and a second drain port are coupled with the flexible bag so as to communicate with the second compartment.

公开(公告)号：US20220288546A1

公开(公告)日：2022-09-15

申请号：US17805301

申请日：2022-06-03

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael E. Goodwin ,  Wade A. Cornia ,  Jacob D. Lee

IPC: B01F27/88 ,  C12M1/00 ,  C12M1/06 ,  B01F27/85 ,  B01F27/213 ,  B01F27/805 ,  B01F27/2121 ,  B01F33/501 ,  B01F33/502 ,  B01F35/513

Abstract: A tube management system includes an elongated rack extending between a first end and an opposing second end; an elongated first shaft having a first end and an opposing second end, the first shaft being secured to the rack; a securing structure secured to the first shaft; a collapsible bag bounding a chamber; and a tubular member projecting from the collapsible bag, wherein the securing structure at least partially encircles the tubular member.

公开(公告)号：US20220228686A1

公开(公告)日：2022-07-21

申请号：US17712501

申请日：2022-04-04

Applicant: Life Technologies Corporation

Inventor： Ryan S. Beus ,  Brandon R. Burtenshaw ,  Eric Davis ,  Patrick L. Draper ,  Michael E. Goodwin ,  Brandon M. Knudsen ,  Jeremy K. Larsen ,  Kevin R. Pickup

IPC: F16L33/207 ,  F16L33/22 ,  B29C65/00 ,  B29C65/68 ,  B29C65/56 ,  A61M39/12

Abstract: A coupling assembly includes: a tubular compression collar having a tubular body made of a resiliently flexible polymeric material and having an interior surface and an opposing exterior surface; an end of a tube disposed within a throughway of the compression collar; and a tube fitting disposed within the passageway of the tube. The tube fitting includes: a tubular stem; a flange radially outwardly projecting from an exterior surface of the stem; and an annular barb encircling and radially outwardly projecting from the exterior surface of the stem, the annular barb including a frustoconical outside face that extends along and outwardly slopes away from the stem as the outside face extends toward the flange. The compression collar radially inwardly compresses the tube against the annular barb of the tube fitting so that a liquid tight seal is formed between the tube and the tube fitting.

公开(公告)号：US11358107B2

公开(公告)日：2022-06-14

申请号：US16196882

申请日：2018-11-20

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael E. Goodwin ,  Wade A. Cornia ,  Jacob D. Lee

IPC: B01F7/16 ,  B01F7/00 ,  B01F13/00 ,  B01F15/00 ,  C12M1/00 ,  C12M1/06 ,  B01F27/88 ,  B01F27/85 ,  B01F27/213 ,  B01F27/805 ,  B01F27/2121 ,  B01F33/501 ,  B01F33/502 ,  B01F35/513 ,  B01F27/113 ,  B01F101/22

Abstract: A bioreactor system includes a support housing having an interior surface bounding a compartment. A rack is secured to the support housing in alignment with the opening. An elongated first shaft has a first end and an opposing second end, the first end of the first shaft being secured to the rack. A structure is secured to the first shaft at or towards the second end of the first shaft, the structure outwardly projecting away from the first shaft. A collapsible bag bounds a chamber and is at least partially disposed within the compartment of the support housing. A member projects from the collapsible bag and passes through the opening on the support housing, the structure supporting or restraining movement of the member.

公开(公告)号：US11175188B2

公开(公告)日：2021-11-16

申请号：US16715057

申请日：2019-12-16

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael E. Goodwin

IPC: G01K1/14 ,  C12M1/26 ,  C12M1/28 ,  C12M1/00 ,  C12M3/00 ,  C12M1/06 ,  C12M1/34 ,  G01N1/10

Abstract: A container system includes a flexible bag, a probe port, and a probe. The probe port includes an elongated tubular member having an interior surface bounding a first passageway extending between a first end and an opposing second end, the tubular member being made of a polymeric or elastomeric material and being flexible. The probe port also includes a flange coupled to the tubular member and radially outwardly projecting therefrom, the flange being secured to the flexible bag so that the first end of the tubular member projects into a chamber of the flexible bag while the second end of the first passageway of the tubular member is accessible from outside of the flexible bag. The probe can be received within the first passageway of the probe port.

公开(公告)号：US11148836B2

公开(公告)日：2021-10-19

申请号：US16385775

申请日：2019-04-16

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael E. Goodwin ,  Jeremy K. Larsen ,  Patrick L. Draper ,  Brandon M. Knudsen

IPC: B65B3/00 ,  B65B1/04 ,  B65B3/02 ,  B65B3/04 ,  B65B51/02 ,  B65B51/22 ,  A61J1/10

Abstract: A method of dispensing a fluid includes coupling a manifold to a fluid source, the manifold including at least portions of opposing flexible sheets welded together to form a fluid flow path therebetween; passing a fluid from the fluid source through the fluid flow path of the manifold and into a plurality of flexible bags coupled to the manifold; sealing closed each of the flexible bags; progressively collapsing the fluid flow path along a length of the manifold so as to force a portion of the fluid remaining within the fluid flow path into one of the flexible bags before all of the flexible bags are sealed closed; and removing each sealed bag from the manifold.

公开(公告)号：US10525425B2

公开(公告)日：2020-01-07

申请号：US14878299

申请日：2015-10-08

Applicant: LIFE TECHNOLOGIES CORPORATION

Inventor： Michael E. Goodwin ,  Jacob D. Lee ,  Whitt F. Woods ,  Patrick L. Draper

IPC: B01F7/16 ,  B01F3/04 ,  B01F7/00 ,  B01F7/22 ,  B01F13/00 ,  B01F15/00 ,  C12M1/00 ,  C12M1/06 ,  B65B1/02 ,  B65B3/04

Abstract: A method for processing a fluid includes removably securing a retention member to a vessel that bounds a chamber; inserting a collapsible bag within the chamber of the vessel; securing the bag to the retention member so that the bag is supported within the chamber of the vessel; and dispensing a fluid into a compartment of the collapsible bag supported within the chamber of the vessel. The fluid can be mixed within bag while the bag is disposed within the vessel.