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公开(公告)号：US12042284B2
公开(公告)日：2024-07-23
申请号：US15878313
申请日：2018-01-23
Applicant: MEDTRONIC MINIMED, INC.
Inventor： Jia Yao , Daniel E. Pesantez , Anuradha Biswas Bhatia , Akhil Srinivasan , Guangping Zhang , Andrea Varsavsky , Raghavendhar Gautham
IPC: A61B5/1486 , A61B5/145 , A61L31/04 , A61L31/14 , C09D5/16 , C12Q1/00 , C12Q1/26 , C12Q1/54 , A61B5/00
CPC classification number: A61B5/14865 , A61B5/1451 , A61B5/14532 , A61L31/04 , A61L31/14 , C09D5/1681 , C12Q1/006 , C12Q1/26 , C12Q1/54 , A61B5/41 , A61L2400/18
Abstract: Embodiments of the invention provide optimized polymeric surfaces adapted for use with implantable medical devices as well as methods for making and using such polymeric surfaces. These polymer surfaces have a constellation of features that function to inhibit or avoid an inflammatory immune response generated by implantable medical devices. Typical embodiments of the invention include an implantable glucose sensor used in the management of diabetes having a polymer surface with the disclosed constellation of features.
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公开(公告)号：US10588575B2
公开(公告)日：2020-03-17
申请号：US15422329
申请日：2017-02-01
Applicant: Medtronic Minimed, Inc.
Inventor： Rebecca K. Gottlieb , Ying Luo , Raghavendhar Gautham , Bradley Liang , Anirban Roy , Kenneth W. Cooper , Rajiv Shah , Barry Keenan
IPC: A61B5/00 , A61M5/172 , A61B5/145 , A61B5/1495 , A61B5/1473
Abstract: Disclosed are a system and method for determining a metric and/or indicator of a reliability of a blood glucose sensor in providing glucose measurements. In one aspect, the metric and/or indicator may be computed based, at least in part, on an observed trend associated with signals generated by the blood glucose sensor.
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公开(公告)号：US10327680B2
公开(公告)日：2019-06-25
申请号：US14980205
申请日：2015-12-28
Applicant: MEDTRONIC MINIMED, INC.
Inventor： Keith Nogueira , Taly G. Engel , Raghavendhar Gautham , Xiaolong Li , Bradley C. Liang , Rajiv Shah , Jaeho Kim , Mike C. Liu , Andy Y. Tsai , Jeffrey Nishida
IPC: A61B5/00 , A61B5/145 , A61B5/1486
Abstract: Electrochemical impedance spectroscopy (EIS) may be used in conjunction with continuous glucose monitoring (CGM) to enable identification of valid and reliable sensor data, as well implementation of Smart Calibration algorithms.
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14.发明授权公开(公告)号：US10156543B2
公开(公告)日：2018-12-18
申请号：US13778630
申请日：2013-02-27
Applicant: MEDTRONIC MINIMED, INC.
Inventor： Ning Yang , Raghavendhar Gautham , Rajiv Shah
IPC: A61B5/05 , G01N27/416 , G01R35/00 , A61B5/145 , A61B5/1473 , A61B5/00 , A61B5/053 , A61B5/1495 , G01N33/66 , A61B5/1459 , A61M5/158 , A61B5/1486 , A61M5/142 , G01N27/02 , G01N33/96 , G01N33/49 , A61M5/172
Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.
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公开(公告)号：US20170143276A1
公开(公告)日：2017-05-25
申请号：US15422329
申请日：2017-02-01
Applicant: Medtronic Minimed, Inc.
Inventor： Rebecca K. Gottlieb , Ying Luo , Raghavendhar Gautham , Bradley Liang , Anirban Roy , Kenneth W. Cooper , Rajiv Shah , Barry Keenan
IPC: A61B5/00 , A61M5/172 , A61B5/1495 , A61B5/145 , A61B5/1473
CPC classification number: A61B5/7221 , A61B5/14503 , A61B5/14532 , A61B5/1473 , A61B5/1495 , A61B5/4839 , A61B5/6849 , A61B5/7275 , A61B5/743 , A61M5/1723 , A61M2005/1726 , A61M2205/3303 , A61M2230/201
Abstract: Disclosed are a system and method for determining a metric and/or indicator of a reliability of a blood glucose sensor in providing glucose measurements. In one aspect, the metric and/or indicator may be computed based, at least in part, on an observed trend associated with signals generated by the blood glucose sensor.
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Patent Agency Ranking
16.发明授权公开(公告)号：US09625415B2
公开(公告)日：2017-04-18
申请号：US15154560
申请日：2016-05-13
Applicant: MEDTRONIC MINIMED, INC.
Inventor： Ning Yang , Raghavendhar Gautham , Bradley C. Liang , Rajiv Shah
IPC: A61B5/1495 , G01N27/416 , G01N27/02 , G01R35/00 , A61B5/145 , A61B5/1473 , G01N33/66 , A61B5/1459 , A61M5/158 , A61B5/1486 , A61B5/00 , A61B5/053 , A61M5/172 , A61M5/142
CPC classification number: G01N27/4163 , A61B5/0537 , A61B5/0538 , A61B5/14503 , A61B5/14532 , A61B5/1459 , A61B5/1473 , A61B5/14865 , A61B5/1495 , A61B5/4839 , A61B5/6849 , A61B5/6852 , A61B5/7203 , A61B5/7221 , A61B5/7225 , A61B5/7242 , A61B5/746 , A61B2562/0214 , A61B2562/04 , A61M5/14244 , A61M5/14276 , A61M5/1582 , A61M5/1723 , A61M2005/1726 , G01N27/026 , G01N27/028 , G01N27/416 , G01N33/49 , G01N33/66 , G01N33/96 , G01R35/00 , G01R35/005
Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.
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17.发明授权公开(公告)号：US09357958B2
公开(公告)日：2016-06-07
申请号：US13778416
申请日：2013-02-27
Applicant: MEDTRONIC MINIMED, INC.
Inventor： Ning Yang , Raghavendhar Gautham , Bradley C. Liang , Rajiv Shah
IPC: A61B5/1495 , G01N27/02 , G01R35/00 , A61B5/145 , A61B5/1473 , G01N33/66 , A61B5/1459 , A61M5/158 , A61B5/1486 , G01N27/416 , A61B5/00 , A61B5/053 , A61M5/172 , A61M5/142
CPC classification number: G01N27/4163 , A61B5/0537 , A61B5/0538 , A61B5/14503 , A61B5/14532 , A61B5/1459 , A61B5/1473 , A61B5/14865 , A61B5/1495 , A61B5/4839 , A61B5/6849 , A61B5/6852 , A61B5/7203 , A61B5/7221 , A61B5/7225 , A61B5/7242 , A61B5/746 , A61B2562/0214 , A61B2562/04 , A61M5/14244 , A61M5/14276 , A61M5/1582 , A61M5/1723 , A61M2005/1726 , G01N27/026 , G01N27/028 , G01N27/416 , G01N33/49 , G01N33/66 , G01N33/96 , G01R35/00 , G01R35/005
Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.
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18.发明申请公开(公告)号：US20150316499A1
公开(公告)日：2015-11-05
申请号：US14267739
申请日：2014-05-01
Applicant: MEDTRONIC MINIMED, INC.
Inventor： Steven C. Jacks , Raghavendhar Gautham , Bradley C. Liang , Megan E. Little , Daniel E. Pesantez , Rajiv Shah
IPC: G01N27/327 , C23C28/00 , C25D3/52 , C25D5/18
CPC classification number: G01N27/416 , A61B5/1451 , A61B5/14532 , A61B2562/02 , A61B2562/125 , C23C28/00 , C25D3/52 , C25D3/567 , C25D5/18 , C25D7/00 , G01N27/30 , G01N27/327
Abstract: A physiological characteristic sensor, a method for forming a physiological characteristic sensor, and a method for forming a platinum deposit having a rough surface are presented here. The method for forming a physiological characteristic sensor includes immersing a sensor electrode in a platinum electrolytic bath. Further, the method includes performing an electrodeposition process by sequentially applying a pulsed signal to the sensor electrode and applying a non-pulsed continuous signal to the sensor electrode to form a platinum deposit on the sensor electrode.
Abstract translation: 这里呈现生理特征传感器，形成生理特征传感器的方法和形成具有粗糙表面的铂沉积物的方法。 用于形成生理特征传感器的方法包括将传感器电极浸入铂电解槽中。 此外，该方法包括通过向传感器电极顺序施加脉冲信号并向传感器电极施加非脉冲连续信号以在传感器电极上形成铂沉积物来执行电沉积处理。
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19.发明授权公开(公告)号：US11938303B2
公开(公告)日：2024-03-26
申请号：US18066212
申请日：2022-12-14
Applicant: MEDTRONIC MINIMED, INC.
Inventor： Steven C. Jacks , Peter Ajemba , Akhil Srinivasan , Jacob E. Pananen , Sarkis Aroyan , Pablo Vazquez , Tri T. Dang , Ashley N. Sullivan , Raghavendhar Gautham
CPC classification number: A61M5/1723 , A61B5/14532 , A61B5/1495 , A61M5/14244 , A61B5/4839 , A61B2560/0223 , A61B2560/0238 , A61M2005/14208 , G16H20/17
Abstract: Techniques disclosed herein relate to determining a calibrated measurement value indicative of a physiological condition of a patient using sensor calibration data and a performance model. In some embodiments, the techniques involve obtaining one or more electrical signals from a sensing element of a sensing arrangement, where the one or more electrical signals are influenced by a physiological condition in a body of a patient. The techniques also involve obtaining calibration data associated with the sensing element from a data storage element of the sensing arrangement, converting the one or more electrical signals into one or more calibrated measurement parameters using the calibration data, obtaining a performance model associated with the sensing element, obtaining personal data associated with the patient, and determining, using the performance model and based on the personal data and the one or more calibrated measurement parameters, a calibrated output value indicative of the physiological condition.
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20.发明申请公开(公告)号：US20230110585A1
公开(公告)日：2023-04-13
申请号：US18066212
申请日：2022-12-14
Applicant: MEDTRONIC MINIMED, INC.
Inventor： Steven C. Jacks , Peter Ajemba , Akhil Srinivasan , Jacob E. Pananen , Sarkis Aroyan , Pablo Vazquez , Tri T. Dang , Ashley N. Sullivan , Raghavendhar Gautham
IPC: A61M5/172 , A61B5/145 , A61M5/142 , A61B5/1495
Abstract: Techniques disclosed herein relate to determining a calibrated measurement value indicative of a physiological condition of a patient using sensor calibration data and a performance model. In some embodiments, the techniques involve obtaining one or more electrical signals from a sensing element of a sensing arrangement, where the one or more electrical signals are influenced by a physiological condition in a body of a patient. The techniques also involve obtaining calibration data associated with the sensing element from a data storage element of the sensing arrangement, converting the one or more electrical signals into one or more calibrated measurement parameters using the calibration data, obtaining a performance model associated with the sensing element, obtaining personal data associated with the patient, and determining, using the performance model and based on the personal data and the one or more calibrated measurement parameters, a calibrated output value indicative of the physiological condition.
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