公开(公告)号：US09974896B2

公开(公告)日：2018-05-22

申请号：US14642847

申请日：2015-03-10

Applicant: Medtronic, Inc.

Inventor： Bryant J. Pudil ,  SuPing Lyu ,  Eric Grovender ,  Christopher M. Hobot ,  Martin T. Gerber

IPC: B01D11/00 ,  A61M1/16 ,  C01B25/45 ,  B01J39/09

CPC classification number: A61M1/1696 ,  B01J39/09 ,  C01B25/45

Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing combinations of acids, bases and salts through a module containing a rechargeable sorbent material such as zirconium phosphate in order to replace ions bound to the zirconium phosphate with hydrogen and sodium ions. The method allows for a customizable zirconium phosphate, with control over the ratios of sodium to hydrogen on the recharged zirconium phosphate.

公开(公告)号：US11759557B2

公开(公告)日：2023-09-19

申请号：US17034250

申请日：2020-09-28

Applicant: Medtronic, Inc.

Inventor： Martin Gerber ,  John Burnes ,  SuPing Lyu ,  Venkatesh R. Manda ,  Bryant Pudil

IPC: A61M1/16 ,  A61B5/00 ,  A61M1/00 ,  A61B5/053 ,  G16H20/17 ,  G16H40/63 ,  A61B5/145 ,  A61M1/34 ,  A61M1/36 ,  A61M1/14 ,  B01D61/00 ,  B01D61/32 ,  A61B5/0295 ,  A61B5/0537 ,  B01D65/02 ,  G16Z99/00 ,  G16H20/40 ,  A61B5/026 ,  A61M1/28

CPC classification number: A61M1/1603 ,  A61B5/0031 ,  A61B5/026 ,  A61B5/0295 ,  A61B5/053 ,  A61B5/0537 ,  A61B5/145 ,  A61B5/14503 ,  A61B5/14535 ,  A61B5/14539 ,  A61B5/14546 ,  A61B5/4836 ,  A61B5/4848 ,  A61B5/6866 ,  A61M1/00 ,  A61M1/14 ,  A61M1/16 ,  A61M1/1601 ,  A61M1/1605 ,  A61M1/1607 ,  A61M1/1613 ,  A61M1/28 ,  A61M1/34 ,  A61M1/342 ,  A61M1/3403 ,  A61M1/361 ,  A61M1/3607 ,  A61M1/3609 ,  A61M1/3612 ,  B01D61/00 ,  B01D61/32 ,  B01D65/02 ,  G16H20/17 ,  G16H20/40 ,  G16H40/63 ,  G16Z99/00 ,  A61B2560/0223 ,  A61M2205/04 ,  A61M2205/18 ,  A61M2205/33 ,  A61M2205/3303 ,  A61M2205/3306 ,  A61M2205/3313 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/3375 ,  A61M2205/3523 ,  A61M2205/50 ,  A61M2205/52 ,  A61M2205/60 ,  A61M2205/70 ,  A61M2230/00 ,  A61M2230/005 ,  A61M2230/20 ,  A61M2230/207 ,  A61M2230/208 ,  A61M2230/65 ,  B01D2321/12 ,  B01D2321/40

Abstract: Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patient parameters. By comparing the patient's past responses to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.

公开(公告)号：US10967112B2

公开(公告)日：2021-04-06

申请号：US15693535

申请日：2017-09-01

Applicant: Medtronic, Inc.

Inventor： Martin Gerber ,  John Burnes ,  SuPing Lyu ,  VenKatesh R. Manda ,  Bryant Pudil

IPC: A61M1/16 ,  A61B5/145 ,  A61B5/00 ,  A61M1/34 ,  A61M1/36 ,  A61M1/00 ,  A61M1/14 ,  A61B5/0295 ,  A61B5/053 ,  A61B5/026 ,  A61M1/28 ,  B01D61/00 ,  B01D61/32 ,  B01D65/02 ,  A61B5/0537 ,  G06F19/00

Abstract: Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patient parameters. By comparing the patient's past responses to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.

公开(公告)号：US20210008265A1

公开(公告)日：2021-01-14

申请号：US17034250

申请日：2020-09-28

Applicant: Medtronic, Inc.

Inventor： Martin Gerber ,  John Burnes ,  SuPing Lyu ,  VenKatesh R. Manda ,  Bryant Pudil

IPC: A61M1/16 ,  A61B5/145 ,  A61B5/00 ,  A61M1/34 ,  A61M1/36 ,  A61M1/00 ,  A61M1/14 ,  B01D61/00 ,  B01D61/32 ,  A61B5/0295 ,  A61B5/053 ,  B01D65/02 ,  A61B5/026 ,  A61M1/28

Abstract: Methods for monitoring patient parameters and blood fluid removal system parameters include identifying those system parameters that result in improved patient parameters or in worsened patient parameters. By comparing the patient's past responses to system parameters or changes in system parameters, a blood fluid removal system may be able to avoid future use of parameters that may harm the patient and may be able to learn which parameters are likely to be most effective in treating the patient in a blood fluid removal session.

公开(公告)号：US10722636B2

公开(公告)日：2020-07-28

申请号：US14887216

申请日：2015-10-19

Applicant: Medtronic, Inc.

Inventor： Thomas D. Kelly ,  SuPing Lyu ,  Bryant J. Pudil ,  Thomas E. Meyer

IPC: A61M1/34 ,  A61M1/16

Abstract: Systems and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The dialysis circuit and an extracorporeal circuit for circulating blood are in fluid communication through the dialysis membrane. The flux of fluid moving between the extracorporeal circuit and the dialysis circuit is modified by the rate at which the control pump is operating such that a rate of ultrafiltration and convective clearance can be controlled. The system provides for the monitoring of an inlet and outlet conductivity of the sorbent cartridge to provide a facility to quantify or monitor the removal of urea by the sorbent cartridge.

公开(公告)号：US20160038666A1

公开(公告)日：2016-02-11

申请号：US14887216

申请日：2015-10-19

Applicant: Medtronic, Inc.

Inventor： Thomas D. Kelly ,  SuPing Lyu ,  Bryant J. Pudil ,  Thomas E. Meyer

IPC: A61M1/34 ,  A61M1/16

CPC classification number: A61M1/3482 ,  A61M1/1696 ,  A61M2202/0021 ,  A61M2202/0413

Abstract: Systems and methods for the performance of kidney replacement therapy having or using a dialyzer, control components, sorbent cartridge and fluid reservoirs configured to be of a weight and size suitable to be worn or carried by an individual requiring treatment are disclosed. The system for performing kidney replacement therapy has a controlled compliance dialysis circuit, where a control pump controls the bi-directional movement of fluid across a dialysis membrane. The dialysis circuit and an extracorporeal circuit for circulating blood are in fluid communication through the dialysis membrane. The flux of fluid moving between the extracorporeal circuit and the dialysis circuit is modified by the rate at which the control pump is operating such that a rate of ultrafiltration and convective clearance can be controlled. The system provides for the monitoring of an inlet and outlet conductivity of the sorbent cartridge to provide a facility to quantify or monitor the removal of urea by the sorbent cartridge.