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27 条记录 (耗时 0.034 秒)

    Saturable light absorber structure and a device incorporating the structure for regenerating a wavelength division multiplexed signal
    11.
    发明授权
    Saturable light absorber structure and a device incorporating the structure for regenerating a wavelength division multiplexed signal 失效
    可饱和光吸收体结构和结合有再生波分复用信号的结构的装置

    公开(公告)号：US07158725B2

    公开(公告)日：2007-01-02

    申请号：US10207887

    申请日：2002-07-31

    申请人： Alexandre Shen ,  Denis Leclerc

    发明人： Alexandre Shen ,  Denis Leclerc

    IPC分类号： H04B10/16 ,  H04J14/02

    CPC分类号： G02F1/3523 ,  B82Y20/00 ,  G02B2006/12126 ,  G02F1/01725 ,  G02F2203/15

    摘要： The invention relates to a saturable light absorber adapted to receive different focused spectral components, wherein the structure of said saturable light absorber comprises microcavities integrated into a substrate and each associated with a respective one of said spectral components, each microcavity comprising a saturable absorber layer delimited by a top reflector and a bottom reflector and being disposed and having dimensions such that it receives only the focused spectral component associated with it.

    摘要翻译： 本发明涉及适于接收不同聚焦光谱分量的可饱和光吸收体，其中所述可饱和光吸收体的结构包括集成到衬底中的每一个与相应的所述光谱分量相关联的微腔，每个微腔包括限定的饱和吸收层 通过顶部反射器和底部反射器设置并具有使其仅接收与其相关联的聚焦光谱分量的尺寸。

    Positive feedback device for processing an optical signal
    14.
    发明授权
    Positive feedback device for processing an optical signal 失效
    用于处理光信号的正反馈装置

    公开(公告)号：US5265111A

    公开(公告)日：1993-11-23

    申请号：US841710

    申请日：1992-02-26

    申请人： Jose Chesnoy ,  Jean-Michel Gabriagues ,  Denis Leclerc

    发明人： Jose Chesnoy ,  Jean-Michel Gabriagues ,  Denis Leclerc

    IPC分类号： H04B10/04 ,  G02F3/02 ,  H01S5/06 ,  H01S5/062 ,  H01S5/068 ,  H04B10/06 ,  H04B10/14 ,  H01S3/10

    CPC分类号： H01S5/068 ,  H01S5/0601 ,  G02F3/026 ,  H01S5/06223

    摘要： A photodiode (26) receives an optical input signal (P1) and an internal optical signal (P2) and supplies in response thereto an internal electrical signal (I2), which in turn controls a laser (4) which effects amplification and supplies the internal optical signal and an output signal (P3). The feedback loop formed by this photodiode and laser leads to a strong non-linearity in the variation of the output signal as a function of the input signal. The invention is useful especially in optical fiber telecommunications systems.

    摘要翻译： 光电二极管（26）接收光输入信号（P1）和内部光信号（P2），并响应于内部电信号（I2）供应光电输入信号（I2），内部电信号（I2）进而控制实现放大的内部激光器（4） 光信号和输出信号（P3）。 由该光电二极管和激光器形成的反馈环路作为输入信号的函数导致输出信号变化的强非线性。 本发明特别适用于光纤通信系统。

    VIRUS-LIKE PARTICLES AND PROCESS FOR PREPARING SAME
    16.
    发明申请
    VIRUS-LIKE PARTICLES AND PROCESS FOR PREPARING SAME 有权
    类似病毒的颗粒及其制备方法

    公开(公告)号：US20140255439A1

    公开(公告)日：2014-09-11

    申请号：US14117365

    申请日：2012-05-01

    申请人： Denis Leclerc ,  Pierre Savard

    发明人： Denis Leclerc ,  Pierre Savard

    IPC分类号： A61K39/12

    CPC分类号： A61K39/12 ,  A61K39/39 ,  C12N2760/10011 ,  C12N2760/16111 ,  C12N2770/26023 ,  C12N2770/26034 ,  C12N2770/26042 ,  Y02A50/403 ,  Y02A50/407 ,  Y02A50/478

    摘要： An in vitro process of preparing virus-like particles (VLPs) from recombinant papaya mosaic virus coat protein and ssRNA, which allows for large scale production of VLPs in high yields, is provided. Also provided are VLPs comprising ssRNA prepared by the in vitro process. The VLPs can be used as adjuvants and when fused to an antigen, as vaccines. The use of the VLPs for stimulation of the innate immune response is also provided.

    摘要翻译： 提供了从重组番木瓜花叶病毒外壳蛋白和ssRNA制备病毒样颗粒（VLPs）的体外方法，其允许以高产量大规模生产VLP。 还提供了通过体外方法制备的包含ssRNA的VLP。 作为疫苗，VLP可以用作佐剂，当与抗原融合时。 还提供了VLP用于刺激先天免疫应答的用途。

    Immunogenic Affinity-Conjugated Antigen Systems Based on Papaya Mosaic Virus and Uses Thereof
    18.
    发明申请
    Immunogenic Affinity-Conjugated Antigen Systems Based on Papaya Mosaic Virus and Uses Thereof 审中-公开
    基于番木瓜花叶病毒的免疫原性亲和共轭抗原系统及其用途

    公开(公告)号：US20100047264A1

    公开(公告)日：2010-02-25

    申请号：US12514970

    申请日：2007-10-25

    申请人： Denis Leclerc

    发明人： Denis Leclerc

    IPC分类号： A61K39/12 ,  C07K14/005 ,  C07H21/04 ,  C12N7/00

    CPC分类号： C12N7/00 ,  A61K39/0275 ,  A61K39/12 ,  A61K39/29 ,  A61K2039/5256 ,  A61K2039/5258 ,  A61K2039/55516 ,  A61K2039/55566 ,  A61K2039/55572 ,  A61K2039/6075 ,  C07K14/005 ,  C07K2319/20 ,  C12N2770/24222 ,  C12N2770/24234 ,  C12N2770/24251 ,  C12N2770/26023 ,  Y02A50/482

    摘要： An affinity-conjugated antigen system (ACAS) comprising one or more antigens conjugated via a plurality of affinity moieties to a papaya mosaic virus (PapMV) or virus-like particle (VLP) derived from the coat protein of PapMV is provided. The affinity moieties are molecules or compounds that are capable of specifically binding to the antigen(s) of interest and which can be attached, for example by chemical or genetic means, to the coat protein of the PapMV or PapMV VLP. The ACAS can optionally further comprise one or more additional antigens, which may be the same as, or different to, the conjugated antigen(s) comprised by the ACAS. Also provided are immunogenic compositions, including vaccines, comprising an ACAS. The immunogenic compositions are useful in the treatment, including prevention, of various diseases and disorders for which a humoral and/or cellular response in the animal is required.

    摘要翻译： 提供了包含通过多个亲和部分缀合的一种或多种抗原与来自PapMV的外壳蛋白的木瓜花叶病毒（PapMV）或病毒样颗粒（VLP））的亲和共轭抗原系统（ACAS）。 亲和部分是能够特异性结合感兴趣的抗原并且可以例如通过化学或遗传方式与PapMV或PapMV VLP的外壳蛋白连接的分子或化合物。 ACAS可以任选地进一步包含一个或多个另外的抗原，其可以与由ACAS组成的缀合的抗原相同或不同。 还提供了包含ACAS的免疫原性组合物，包括疫苗。 免疫原性组合物可用于治疗需要动物体液和/或细胞应答的各种疾病和病症，包括预防。

    Hybrid interface synchronization method and driver-client model for high availability systems
    19.
    发明授权
    Hybrid interface synchronization method and driver-client model for high availability systems 有权
    混合接口同步方法和高可用性系统的驱动程序 - 客户端模型

    公开(公告)号：US07590760B1

    公开(公告)日：2009-09-15

    申请号：US10156556

    申请日：2002-05-24

    申请人： Donald Banks ,  Vijay Savla ,  Timothy Donahue ,  Balachander Chandrasekaran ,  Denis Leclerc

    发明人： Donald Banks ,  Vijay Savla ,  Timothy Donahue ,  Balachander Chandrasekaran ,  Denis Leclerc

    IPC分类号： G06F15/16 ,  G06F15/173 ,  G06F11/00

    CPC分类号： G06F11/2097 ,  G06F11/2028 ,  G06F11/2038 ,  H04L41/0663

    摘要： A system and method for supporting a “hitless” switchover from an Active to a Standby processor uses a hybrid synchronization of interface states to allow applications that have been modified to have HA aware features and non-modified applications to function on the system. An interface description data block on the Standby RP is synchronized to the interface description data block on the Active RP and is maintained in a shadow state when the Active RP controls the system. In the event of a switchover between the RPs the interface description data block on the Standby RP is copied from the shadow state to a real state and applications on the Standby RP are notified of a status change.

    摘要翻译： 用于支持从主动到待机处理器的“无间断”切换的系统和方法使用接口状态的混合同步，以允许经过修改的应用程序具有HA感知功能和未修改的应用程序在系统上运行。 备用RP上的接口描述数据块与Active RP上的接口描述数据块同步，并在Active RP控制系统时保持在阴影状态。 在RP之间切换时，备用RP上的接口描述数据块从影子状态复制到实际状态，备用RP上的应用程序通知状态变化。

    Semiconductor optical component and a method of fabricating it
    20.
    发明授权
    Semiconductor optical component and a method of fabricating it 有权
    半导体光学元件及其制造方法

    公开(公告)号：US06777768B2

    公开(公告)日：2004-08-17

    申请号：US10233398

    申请日：2002-09-04

    申请人： Léon Goldstein ,  Christophe Ougier ,  Denis Leclerc ,  Jean Decobert

    发明人： Léon Goldstein ,  Christophe Ougier ,  Denis Leclerc ,  Jean Decobert

    IPC分类号： H01L310232

    CPC分类号： H01S5/50 ,  H01S5/1064 ,  H01S5/3054 ,  H01S5/3215

    摘要： A semiconductor optical component is disclosed which includes a semiconductor material confinement layer containing acceptor dopants such that the doping is p-type doping. The confinement layer is deposited on another semiconductor layer and defines a plane parallel to the other semiconductor layer. Furthermore, the p-type doping concentration of the confinement layer has at least one gradient significantly different from zero in one direction in the plane. A method of fabricating the component is also disclosed.

    摘要翻译： 公开了一种半导体光学部件，其包括含有受主掺杂剂的半导体材料限制层，使得掺杂为p型掺杂。 限制层沉积在另一个半导体层上并限定平行于另一个半导体层的平面。 此外，限制层的p型掺杂浓度在平面中具有至少一个与零在一个方向上不同的梯度。 还公开了一种制造该部件的方法。