公开(公告)号：USD741993S1

公开(公告)日：2015-10-27

申请号：US29480088

申请日：2014-01-23

Applicant: SEKISUI MEDICAL CO., LTD. ,  SEKISUI TECHNO MOLDING CO., LTD.

Designer： Satoru Tominaga ,  Takashi Yosida ,  Takuya Yotani ,  Hiroaki Taira ,  Yuriko Yamada

公开(公告)号：USD741472S1

公开(公告)日：2015-10-20

申请号：US29480097

申请日：2014-01-23

Applicant: SEKISUI MEDICAL CO., LTD.

Designer： Takuya Yotani ,  Hiroaki Taira ,  Yuriko Yamada ,  Hideki Muraki

公开(公告)号：US10550426B2

公开(公告)日：2020-02-04

申请号：US14771936

申请日：2014-03-07

Applicant: SEKISUI MEDICAL CO., LTD. ,  MIE UNIVERSITY

Inventor： Takuya Yotani ,  Tsutomu Nobori

IPC: C12Q1/68 ,  C12Q1/6848 ,  C12Q1/686 ,  C12Q1/6827 ,  G01N30/96

Abstract: Provided is a rapid and simple method of detecting methylated DNA. The method of detecting methylated DNA includes the following steps of: (1) treating sample DNA with a hydrogen sulfite; (2) amplifying the sample DNA treated with the hydrogen sulfite by PCR; and (3) subjecting the resultant PCR amplification product to ion-exchange chromatography.

公开(公告)号：US09778232B2

公开(公告)日：2017-10-03

申请号：US14775402

申请日：2014-03-11

Applicant: Sekisui Medical Co., Ltd.

Inventor： Takuya Yotani ,  Takayuki Oka ,  Hideki Muraki

IPC: G01N30/60 ,  G01N30/16 ,  G01N30/88

CPC classification number: G01N30/6026 ,  G01N30/16 ,  G01N30/6004 ,  G01N30/603 ,  G01N30/6047 ,  G01N30/6052 ,  G01N30/606 ,  G01N2030/8822

Abstract: A cylindrical column body (101) holds a filler. A pair of end caps (105, 106) covers both ends of the column body (101) and has a flow hole for a carrier liquid (111, 112) arranged in the center thereof. An end surface on the side of a large diameter portion (113a, 114a) of a pair of columnar joint members (113, 114) contacts an end surface of the pair of end caps (105, 106) and also has a communication hole (115, 116) arranged in the center thereof. A sealing member (117, 118) is arranged on a contact surface between the end cap (105, 106) and the joint member (113, 114). A bottomed cylindrical case (121) accommodates the pair of end caps (105, 106) and a large diameter portion of the pair of joint members (113, 114) in an engaged state. A cover member (124) is detachably installed on a side of an opening of the case (121).

公开(公告)号：US09689848B2

公开(公告)日：2017-06-27

申请号：US15026175

申请日：2014-09-30

Applicant: SEKISUI MEDICAL CO., LTD.

Inventor： Takuya Yotani ,  Yuriko Nemoto ,  Hideki Muraki

IPC: B01D15/22 ,  G01D11/24 ,  G01N30/60 ,  B65D41/04 ,  B65D53/02

CPC classification number: G01N30/6047 ,  B01D15/20 ,  B65D41/0407 ,  B65D53/02 ,  G01N30/6004

Abstract: Provided is a chromatography column stored in a storage container. The storage container for the column includes: a container body for storing the chromatography column; and a cover threadedly engaging with the container body. A groove for threaded engagement with the cover is formed in an inner wall of the container body. Sealing members are arranged on an inner bottom surface of the container body and a lower surface of the cover, respectively. When the container body and the cover are threadedly engaged with each other, the cover enters the container body to cause the sealing members on the inner bottom surface of the container body and the lower surface of the cover to press both a lower surface and an upper surface of the column, to thereby fix the column inside the container body and seal a fluid passage hole of the column.

公开(公告)号：US20160223501A1

公开(公告)日：2016-08-04

申请号：US15026175

申请日：2014-09-30

Applicant: SEKISUI MEDICAL CO., LTD.

Inventor： Takuya Yotani ,  Yuriko Nemoto ,  Hideki Muraki

IPC: G01N30/60 ,  B65D53/02 ,  B65D41/04

CPC classification number: G01N30/6047 ,  B01D15/20 ,  B65D41/0407 ,  B65D53/02 ,  G01N30/6004

Abstract: Provided is a chromatography column stored in a storage container. The storage container for the column includes: a container body for storing the chromatography column; and a cover threadedly engaging with the container body. A groove for threaded engagement with the cover is formed in an inner wall of the container body. Sealing members are arranged on an inner bottom surface of the container body and a lower surface of the cover, respectively. When the container body and the cover are threadedly engaged with each other, the cover enters the container body to cause the sealing members on the inner bottom surface of the container body and the lower surface of the cover to press both a lower surface and an upper surface of the column, to thereby fix the column inside the container body and seal a fluid passage hole of the column.

Abstract translation: 提供存储在存储容器中的色谱柱。 该柱的储存容器包括：用于储存色谱柱的容器体; 以及与容器主体螺纹接合的盖。 在容器主体的内壁上形成有用于与盖接合的槽。 密封构件分别设置在容器主体的内底表面和盖的下表面上。 当容器主体和盖子彼此螺纹接合时，盖子进入容器主体，使密封件在容器主体的内底表面和盖的下表面上压下下表面和上部 从而将柱固定在容器主体内并密封柱的流体通道孔。

公开(公告)号：USD741994S1

公开(公告)日：2015-10-27

申请号：US29480090

申请日：2014-01-23

Applicant: SEKISUI MEDICAL CO., LTD. ,  SEKISUI TECHNO MOLDING CO., LTD.

Designer： Satoru Tominaga ,  Takashi Yosida ,  Takuya Yotani ,  Hiroaki Taira ,  Yuriko Yamada

公开(公告)号：USD719671S1

公开(公告)日：2014-12-16

申请号：US29480094

申请日：2014-01-23

Applicant: Sekisui Medical Co., Ltd.

Designer： Masato Nishikawa ,  Takayuki Oka ,  Takuya Yotani

公开(公告)号：US09889447B2

公开(公告)日：2018-02-13

申请号：US14908073

申请日：2014-07-25

Applicant: SEKISUI MEDICAL CO., LTD. ,  SEKISUI TECHNO MOLDING CO., LTD.

Inventor： Yuriko Nemoto ,  Hiroaki Taira ,  Takuya Yotani ,  Satoru Tominaga

IPC: A61J1/06 ,  B01L3/00 ,  G01N21/00 ,  G01N1/10 ,  G01N35/10 ,  G01N30/02 ,  G01N30/88

CPC classification number: B01L3/52 ,  B01L3/523 ,  B01L3/527 ,  B01L2200/025 ,  B01L2200/026 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/0609 ,  B01L2300/0672 ,  B01L2300/0809 ,  B01L2300/12 ,  B01L2300/123 ,  G01N30/02 ,  G01N35/1002 ,  G01N35/1079 ,  G01N2030/027 ,  G01N2030/8822

Abstract: Provided are a reagent supply method and device capable of using up a reagent in a container without a remnant to the extent possible, and supplying the reagent to an analysis device without mixing air bubbles even when the remaining amount of the reagent is extremely small. The reagent supply device includes: at least one reagent container including: a container body for storing a liquid reagent; and a reagent supply port arranged on the container body; and a support member for supporting the at least one reagent container so that the reagent supply port is positioned on a lower side of the container body. The reagent supply port is sealed by a plug including at least one nozzle penetration portion. The at least one nozzle penetration portion is formed of a material having a Shore hardness of from A5° to A90°.

公开(公告)号：US09841406B2

公开(公告)日：2017-12-12

申请号：US14786397

申请日：2014-04-22

Applicant: Sekisui Medical Co., Ltd.

Inventor： Takuya Yotani ,  Hiroaki Taira ,  Takayuki Oka ,  Hideki Muraki

IPC: G01N30/20 ,  G01N35/10 ,  G01N33/49

CPC classification number: G01N30/20 ,  G01N33/491 ,  G01N35/1097 ,  G01N2030/201 ,  G01N2030/202 ,  G01N2030/207

Abstract: A switching valve includes: (A) a rotor including: (1) a center pipe connection port, (2) a first in-valve flow path in communication with the center pipe connection port, and (3) an arc-like second in-valve flow path; (B) a stator including: (4) a first pipe connection port group which is brought into communication independently with the center pipe connection port via the first in-valve flow path when the rotor is turned, and (5) a second pipe connection port group which is brought into mutual communication via the second in-valve flow path when the rotor is turned; and (C) an arrangement of the rotor and the stator satisfying the following relationship: the state of communication or non-communication among the second pipe connection port group via the second in-valve flow path is switched in accordance with the state of communication between the first pipe connection port group and the center pipe connection port.