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11.发明授权Hydrophilic polymeric coatings for medical articles with visualization moiety 有权具有可视化部分的医疗用品的亲水性聚合物涂层公开(公告)号：US08956682B2
公开(公告)日：2015-02-17
申请号：US13855260
申请日：2013-04-02
Applicant: SurModics, Inc.
Inventor： Nathan A. Lockwood , Bruce M. Jelle , Aleksey V. Kurdyumov
IPC: A61L33/00 , A61F2/00 , A61K9/14 , B05B5/00 , A01N35/00 , A61K31/12 , C09D5/22 , C09D5/00 , B05D3/06 , A61L29/08 , A61L29/14 , A61L29/18
CPC classification number: C09D5/22 , A61L29/085 , A61L29/14 , A61L29/18 , A61L2420/02 , B05D3/067 , C09D5/00 , Y10T428/31725 , Y10T428/31938 , C08L39/06
Abstract: The invention is directed to medical device coatings, such as coated guidewires and catheters, containing a visualization moiety providing color to the coating in ambient or applied light. The coating allows for visual or machine inspection of coating properties such as uniformity of coverage. In some embodiments the coatings include the visualization moiety and an activated UV photogroup, which is used to provide covalent bonding in the coating. The visualization moiety can be in particulate form and entrained in the coating, or can be covalently bonded to the hydrophilic polymer backbone. In other embodiments the visualization moiety includes a stilbene chemical group. Exemplary coatings include a hydrophilic vinyl pyrrolidone polymer, which can provide lubricity to the device surface, along with the colored properties.
Abstract translation: 本发明涉及医疗器械涂层，例如涂覆的导线和导管，其包含在环境或应用光下为涂层提供颜色的可视化部分。 涂层允许对涂层性能进行视觉或机器检查，例如覆盖的均匀性。 在一些实施方案中，涂层包括可视化部分和活化的UV光电子组，其用于在涂层中提供共价键合。 可视化部分可以是颗粒形式并夹带在涂层中，或者可以共价键合到亲水性聚合物主链上。 在其它实施方案中，可视化部分包括茋化学基团。 示例性涂层包括亲水性乙烯基吡咯烷酮聚合物，其可以提供对器件表面的润滑性以及着色性质。
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公开(公告)号：US20140200411A1
公开(公告)日：2014-07-17
申请号：US14152667
申请日：2014-01-10
Applicant: SurModics, Inc.
Inventor： Bruce M. Jelle , Aleksey V. Kurdyumov , Joseph Schmidt McGonigle , Robert W. Hergenrother , Nathan A. Lockwood , Joseph Ventura , Sean M. Stucke
CPC classification number: A61L31/10 , A61B2562/125 , A61L31/14 , A61N1/0404 , A61N1/05 , C07D495/04 , C07D519/00 , C08G61/02 , C08G61/124 , C08G61/126 , C08G73/0266 , C08G2261/1424 , C08G2261/1426 , C08G2261/1428 , C08G2261/143 , C08G2261/144 , C08G2261/145 , C08G2261/148 , C08G2261/3221 , C08G2261/3223 , C08G2261/3422 , C08G2261/43 , C08G2261/76 , C08G2261/77 , C08G2261/90 , C08G2261/94 , C09D5/24 , H01B1/127 , Y10T428/31507 , Y10T428/31533
Abstract: Disclosed herein are activatable conductive compositions and methods of making and using activatable conductive compositions. In particular, activatable conductive monomers polymers are described and electrically conductive coatings that include activatable conductive polymers.
Abstract translation: 本文公开了可激活的导电组合物和制备和使用可活化导电组合物的方法。 特别地，描述了可激活的导电单体聚合物和包括可激活的导电聚合物的导电涂层。
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13.发明申请公开(公告)号：US20130261566A1
公开(公告)日：2013-10-03
申请号：US13855260
申请日：2013-04-02
Applicant: SURMODICS, INC.
Inventor： Nathan A. Lockwood , Bruce M. Jelle , Aleksey V. Kurdyumov
CPC classification number: C09D5/22 , A61L29/085 , A61L29/14 , A61L29/18 , A61L2420/02 , B05D3/067 , C09D5/00 , Y10T428/31725 , Y10T428/31938 , C08L39/06
Abstract: The invention is directed to medical device coatings, such as coated guidewires and catheters, containing a visualization moiety providing color to the coating in ambient or applied light. The coating allows for visual or machine inspection of coating properties such as uniformity of coverage. In some embodiments the coatings include the visualization moiety and an activated UV photogroup, which is used to provide covalent bonding in the coating. The visualization moiety can be in particulate form and entrained in the coating, or can be covalently bonded to the hydrophilic polymer backbone. In other embodiments the visualization moiety includes a stilbene chemical group. Exemplary coatings include a hydrophilic vinyl pyrrolidone polymer, which can provide lubricity to the device surface, along with the colored properties.
Abstract translation: 本发明涉及医疗器械涂层，例如涂覆的导线和导管，其包含在环境或应用光下为涂层提供颜色的可视化部分。 涂层允许对涂层性能进行视觉或机器检查，例如覆盖的均匀性。 在一些实施方案中，涂层包括可视化部分和活化的UV光电子组，其用于在涂层中提供共价键合。 可视化部分可以是颗粒形式并夹带在涂层中，或者可以共价键合到亲水性聚合物主链上。 在其它实施方案中，可视化部分包括茋化学基团。 示例性涂层包括亲水性乙烯基吡咯烷酮聚合物，其可以提供对器件表面的润滑性以及着色性质。
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公开(公告)号：US11576774B2
公开(公告)日：2023-02-14
申请号：US16914950
申请日：2020-06-29
Applicant: Surmodics, Inc.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号：US20210015613A1
公开(公告)日：2021-01-21
申请号：US16914950
申请日：2020-06-29
Applicant: Surmodics, Inc.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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Patent Agency Ranking
公开(公告)号：US20170367824A1
公开(公告)日：2017-12-28
申请号：US15543704
申请日：2016-01-14
Applicant: SURMODICS, INC.
Inventor： Bruce M. Jelle , Joram Slager , Joseph S. McGonigle , Rick Murphy , Andrew G. Bach , Teryl L. Woodwick Sides , Ambereen Angamuthu , Sean Lundquist , Gary Opperman , Nathan A. Lockwood
CPC classification number: A61F2/2433 , A61M25/0102 , A61M25/0668 , A61M25/09041 , A61M25/10 , A61M2025/0681 , A61M2025/1081
Abstract: The disclosure provides insertion tools and articles that facilitate entry of a medical device, such as a balloon catheter, into the body. In embodiments the insertion tools have an elongate hollow body (50) that is able to protect a portion of a medical device, such as a balloon of a balloon catheter, during an insertion procedure. In one embodiment the insertion tool has an elongate hollow body (131), a tapered distal end (135), and a locking mechanism (133) at the proximal end which can secure a portion of a balloon catheter. An opening at the distal end can allow passage of the balloon in a folded uninflated state.
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公开(公告)号：US20170281907A1
公开(公告)日：2017-10-05
申请号：US15467554
申请日：2017-03-23
Applicant: Surmodics, Inc.
Inventor： Bruce M. Jelle , Joram Slager , Joseph Schmidt McGonigle , Nathan A. Lockwood
Abstract: Embodiments herein include an insertion tool for inserting a medical device into another medical device, such as a hemostasis sealing valve, and related methods. In an embodiment, an insertion tool includes a guide sheath and a protection tube. The guide sheath can include a flared proximal end. The guide sheath can further include a central lumen. The guide sheath can further include a locking notch disposed on the inner surface between the proximal end and the distal end. The protection tube can include a flared proximal end. A portion of the protection tube can be situated within the central lumen of the guide sheath. The flared proximal end of the protection tube can be sized to fit within the locking notch and can have an outer diameter larger than portions of the inner surface immediately adjacent to the locking notch. Other embodiments are also included herein.
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公开(公告)号：US09629945B2
公开(公告)日：2017-04-25
申请号：US14104208
申请日：2013-12-12
Applicant: SurModics, Inc.
Inventor： Aleksey V. Kurdyumov , Dale G. Swan , Nathan A. Lockwood , Bruce M. Jelle
IPC: C07C233/81 , C07C271/58 , C07C309/51 , A61L31/14 , A61L31/10 , C07D251/68 , C07C235/84 , C07C309/46 , A61B1/005 , C07D251/54 , A61B1/00
CPC classification number: A61L31/14 , A61B1/00135 , A61B1/005 , A61L31/10 , C07C235/84 , C07C309/46 , C07D251/54 , C07D251/68 , Y10T428/31942
Abstract: The invention is directed to latent reactive and polymerizable derivatives of fluorescent stilbene-based compounds. The compounds can be used to provide articles with a fluorescence property, such as medical devices (e.g., catheters). The fluorescent compounds can be used in association with polymers, or can be incorporated into polymers, and the polymers used in a coating composition on the article surface. The compounds allow for visual or machine inspection of coating properties such as uniformity of coverage.
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公开(公告)号：US20160089480A1
公开(公告)日：2016-03-31
申请号：US14860128
申请日：2015-09-21
Applicant: SurModics, Inc.
Inventor： Ralph A. Chappa , Nathan A. Lockwood , Joseph Schmidt McGonigle
CPC classification number: A61L29/14 , A61L29/049 , A61L29/085 , A61L31/041 , A61L31/10 , A61L31/14 , A61L2400/10 , A61L2420/06 , C08J3/203 , C08J2375/04 , C08J2429/10 , C08J2437/00 , C08L73/02 , C08L75/04
Abstract: Embodiments of the invention include medical device elements formed from polymers with lubricious properties. In an embodiment, a method of forming a medical device element is included. The method can include mixing a first polymeric component and a second polymeric component to form a polymer mixture. The method can further include forming the polymer mixture into the medical device element. The method can also include treating the polymer mixture with at least one of an acid or a base. In an embodiment, a medical device is included. The medical device can include a lubricious element, the lubricious element comprising a mixture of a first polymeric component and a second polymeric component. The second polymeric component can include a polymer that is treated with at least one of an acid or a base after formation of the element. Other embodiments are also included herein.
Abstract translation: 本发明的实施方案包括由具有光滑性质的聚合物形成的医疗装置元件。 在一个实施例中，包括形成医疗装置元件的方法。 该方法可以包括混合第一聚合物组分和第二聚合物组分以形成聚合物混合物。 该方法还可以包括将聚合物混合物形成到医疗装置元件中。 该方法还可以包括用酸或碱中的至少一种处理聚合物混合物。 在一个实施例中，包括医疗装置。 医疗装置可以包括润滑元件，润滑元件包括第一聚合物组分和第二聚合物组分的混合物。 第二聚合物组分可以包括在形成元素之后用至少一种酸或碱处理的聚合物。 本文还包括其它实施例。
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公开(公告)号：US20160022502A1
公开(公告)日：2016-01-28
申请号：US14819955
申请日：2015-08-06
Applicant: SurModics, Inc.
Inventor： Shawn Fuller , Bryan A. Claseman , Joram Slager , Jeffrey J. Missling , Gary Maharaj , Gary W. Opperman , Nathan A. Lockwood , Robert W. Hergenrother , Charles Olson
IPC: A61F13/00
CPC classification number: A61F13/00068 , A61F13/00021 , A61F13/00029 , A61F13/8405 , A61F2013/00153 , A61F2013/00327 , A61F2013/00331 , A61F2013/00357 , A61F2013/00557 , A61L15/22 , A61L15/44 , A61L15/60 , A61L2300/102 , A61L2300/208
Abstract: Embodiments of the invention include wound packing devices and methods of making and using the same. In an embodiment, the invention includes a wound packing device including a plurality of spacing elements capable of absorbing exudate, wherein the surface of the spacing elements resist colonization by microorganisms. The wound packing device can also include a connector connecting the plurality of spacing elements to one another. Other embodiments are also included herein.
Abstract translation: 本发明的实施例包括伤口包装装置及其制造和使用方法。 在一个实施方案中，本发明包括包含能够吸收渗出物的多个间隔元件的伤口包装装置，其中间隔元件的表面抵抗微生物的定居。 卷绕包装装置还可以包括将多个间隔元件彼此连接的连接器。 本文还包括其它实施例。
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