公开(公告)号：US20240302359A1

公开(公告)日：2024-09-12

申请号：US18666008

申请日：2024-05-16

Applicant: Meso Scale Technologies, LLC.

Inventor： Jeff Debad

IPC: G01N33/53 ,  G01N21/66 ,  G01N35/02

CPC classification number: G01N33/5308 ,  G01N21/66 ,  G01N35/02 ,  G01N2201/0484 ,  G01N2800/28

Abstract: The present invention relates to assays, methods, and kits to assess traumatic brain injury (TBI) in a subject. The present invention also relates to ultrasensitive assays for GFAP, tau, CKBB, IL-1β, IL-2, IL-6, IL-10, IL-22, IP-10, TNFα, TSLP, NFL, and/or NFH.

公开(公告)号：US20230288331A1

公开(公告)日：2023-09-14

申请号：US18180228

申请日：2023-03-08

Applicant: ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY

Inventor： Shaopeng WANG ,  Yunlei ZHAO ,  Guangzhong MA

IPC: G01N21/51 ,  B82Y15/00

CPC classification number: G01N21/51 ,  B82Y15/00 ,  G01N2201/0461 ,  G01N2201/0484 ,  G01N2201/067

Abstract: Provided herein are methods of determining molecular binding kinetics on particles, such as magnetic nanoparticles. In some embodiments, the methods include introducing an incident light from a light source toward a sample container that comprises a particle-bound biomolecule-ligand composition comprising a plurality of particle-bound biomolecules and a plurality of ligands that binds, or is capable of binding, to biomolecules of the plurality of particle-bound biomolecules, detecting light scattered from particle-bound biomolecule-ligand complexes in the particle-bound biomolecule-ligand composition over a duration to produce a set of imaging data using the detector, and determining size or volume changes of one or more of the particle-bound biomolecule-ligand complexes during at least a portion of the duration from the set of imaging data to thereby determine the molecular binding kinetics on the particles. Related systems and computer readable media are also provided.

公开(公告)号：US20230266236A1

公开(公告)日：2023-08-24

申请号：US18173035

申请日：2023-02-22

Applicant: Hyperspectral Corp.

Inventor： Euan Mowat ,  Matthew Theurer ,  Sarah Rachel Hernandez ,  Mario Martinez

IPC: G01N21/31 ,  G01N21/27

CPC classification number: G01N21/314 ,  G01N21/274 ,  G01N2021/317 ,  G01N2201/12784 ,  G01N2201/0484 ,  G01N2201/061 ,  G01N2021/0125

Abstract: An example system includes a light intensity measuring apparatus couplable to a food processing apparatus and a computing system. The light intensity measuring apparatus includes a chamber configured to receive a water sample from the food processing apparatus, a light source, a detector configured to detect light that has passed through the water sample and measure multiple times intensities of wavelengths of the light to obtain multiple sets of measured intensities of wavelengths, and a communication module configured to provide the multiple sets of measured intensities of wavelengths. The computing system may receive the multiple sets of measured intensities, process the multiple sets to obtain a set of values, apply a first set of decision trees to the set of values to obtain a first result indicating a positive or negative foodborne pathogen detection, generate a notification indicating either the positive of negative detection, and provide the notification.

公开(公告)号：US20060006237A1

公开(公告)日：2006-01-12

申请号：US11174296

申请日：2005-07-01

Applicant: Debra Sillman ,  Xiangyang Zhou ,  Chetan Jadhaw ,  Herbert Cattell ,  Jayati Ghosh

Inventor： Debra Sillman ,  Xiangyang Zhou ,  Chetan Jadhaw ,  Herbert Cattell ,  Jayati Ghosh

IPC: G06F17/00

CPC classification number: G01N21/6452 ,  G01N33/52 ,  G01N33/582 ,  G01N33/68 ,  G01N2201/0484

Abstract: Methods for programming an array scanner to scan a plurality of biopolymer arrays are provided. In the subject methods, individual scanning parameters for at least two different arrays of the plurality of arrays to be scanned are selected and input into the array scanner prior to scanning the plurality arrays. The programmed scanner then scans the plurality of arrays according to the pre-selected scanning parameters Also provided are scanners programmed according to the subject methods, as well as computer programming that provides for programming of scanners according to the subject methods. The subject methods and compositions find use in a variety of different applications, including both genomics and proteomics applications.

Abstract translation: 提供了对阵列扫描器进行编程以扫描多个生物聚合物阵列的方法。 在主题方法中，在扫描多个阵列之前，选择要扫描的多个阵列的至少两个不同阵列的各个扫描参数并将其输入阵列扫描器。 编程的扫描仪然后根据预先选择的扫描参数扫描多个阵列。还提供了根据主题方法编程的扫描器以及根据主题方法提供对扫描仪的编程的计算机编程。 主题方法和组合物可用于各种不同的应用，包括基因组学和蛋白质组学应用。

公开(公告)号：US06913200B2

公开(公告)日：2005-07-05

申请号：US10301471

申请日：2002-11-20

Applicant: Debra Ann Sillman ,  Xiangyang Zhou ,  Chetan D Jadhaw ,  Herbert F. Cattell ,  Jayati Ghosh

Inventor： Debra Ann Sillman ,  Xiangyang Zhou ,  Chetan D Jadhaw ,  Herbert F. Cattell ,  Jayati Ghosh

IPC: G01N21/64 ,  G01N33/52 ,  G01N33/58 ,  G01N33/68 ,  G06F17/00 ,  G06F7/10 ,  G06F19/00

CPC classification number: G01N21/6452 ,  G01N33/52 ,  G01N33/582 ,  G01N33/68 ,  G01N2201/0484

Abstract: Methods for programming an array scanner to scan a plurality of biopolymer arrays are provided. In the subject methods, individual scanning parameters for at least two different arrays of the plurality of arrays to be scanned are selected and input into the array scanner prior to scanning the plurality arrays. The programmed scanner then scans the plurality of arrays according to the pre-selected scanning parametersAlso provided are scanners programmed according to the subject methods, as well as computer programming that provides for programming of scanners according to the subject methods. The subject methods and compositions find use in a variety of different applications, including both genomics and proteomics applications.

Abstract translation: 提供了对阵列扫描器进行编程以扫描多个生物聚合物阵列的方法。 在主题方法中，在扫描多个阵列之前，选择要扫描的多个阵列的至少两个不同阵列的各个扫描参数并将其输入阵列扫描器。 编程的扫描仪然后根据预先选择的扫描参数扫描多个阵列。还提供根据主题方法编程的扫描仪，以及根据主题方法提供对扫描仪的编程的计算机编程。 主题方法和组合物可用于各种不同的应用，包括基因组学和蛋白质组学应用。

公开(公告)号：US20050014281A1

公开(公告)日：2005-01-20

申请号：US10492899

申请日：2002-10-10

Applicant: Pieter Langeveld ,  Karl Hemert Van ,  Johannes Hendrik Kerkhof ,  Jacobus Stark

Inventor： Pieter Langeveld ,  Karl Hemert Van ,  Johannes Hendrik Kerkhof ,  Jacobus Stark

IPC: C12Q1/18 ,  G01J3/46 ,  G01J3/52 ,  G01N21/86 ,  G01N31/22 ,  G01N33/04 ,  G01N33/49 ,  G01N33/493

CPC classification number: G01J3/52 ,  G01J3/46 ,  G01J3/462 ,  G01J2003/466 ,  G01N31/221 ,  G01N33/04 ,  G01N33/49 ,  G01N33/493 ,  G01N2201/0484 ,  G01N2201/102

Abstract: Detection arrangement and method for detecting presence of a residue in a sample by determining color values of the sample, associated with the L*a*b color model, where a value of a composite parameter Z is calculated as follows: Z=wL+waa+wbb where wL, wa, and wb are weighting factors having a value depending on said residue and said sample, and a determination is made whether or not said sample comprises more or less than a predetermined amount of said residue in dependence on said value of said composite parameter Z. In a preferred embodiment, the arrangement is used to detect antibiotic residues, e.g. penicillin-G, in food products, e.g. milk, or body fluids, e.g. blood, urine.

Abstract translation: 用于通过确定与L * a * b颜色模型相关联的样品的颜色值来检测样品中残留物的检测装置和方法，其中复合参数Z的值如下计算：Z = wL + waa + wbb其中wL，wa和wb是具有取决于所述残基和所述样品的值的加权因子，并且根据所述残基和所述样品的值是否确定所述样品是否包含大于或小于预定量的所述残基 所述复合参数Z。在优选实施方案中，该装置用于检测抗生素残留物，例如， 青霉素G，在食品中，例如 牛奶或体液，例如， 血，尿。

公开(公告)号：US4710874A

公开(公告)日：1987-12-01

申请号：US743596

申请日：1985-06-11

Applicant: Paul-Henri Cinqualbre

Inventor： Paul-Henri Cinqualbre

IPC: G01N15/05 ,  G01N33/48 ,  G01N21/51 ,  G06F15/42

CPC classification number: G01N15/05 ,  G01N2201/0484

Abstract: An apparatus and a method for continuous display of a particle sedimentation rate in a liquid includes a rotary support device adapted to hold a plurality of light-transparent containers, and wherein each container holds a liquid. Any container may be selected to be observed so that at least a portion of the selected container may be observed from the exterior. A light source illuminates the selected container, and an image-forming device is arranged to form an image of the aforesaid portion of the selected container, and the liquid held therein. Video signals are created from the so-formed image, and a computer is arranged to process the video signals. A transmission conduit transmits the video signals from the image-forming device to the computer, and a display is provided for displaying the signals processed by the computer.

Abstract translation: 用于连续显示液体中的颗粒沉降速率的装置和方法包括适于容纳多个透光容器的旋转支撑装置，并且其中每个容器保持液体。 可以选择任何容器进行观察，使得可以从外部观察所选择的容器的至少一部分。 光源照亮所选择的容器，并且图像形成装置被布置成形成所选择的容器的上述部分的图像，并且保持在其中的液体。 视频信号是从如此形成的图像创建的，并且计算机被布置成处理视频信号。 传输导管将图像信号从图像形成装置发送到计算机，并且提供显示器以显示由计算机处理的信号。

公开(公告)号：US20240295503A1

公开(公告)日：2024-09-05

申请号：US18653971

申请日：2024-05-02

Applicant: Applied Materials, Inc.

Inventor： Asaf SCHLEZINGER

IPC: G01N21/90 ,  G01N35/04

CPC classification number: G01N21/9009 ,  G01N35/04 ,  G01N2035/0406 ,  G01N2035/0415 ,  G01N2201/0484 ,  G01N2201/0636

Abstract: Methods and apparatus of inspection tools for inspecting impurities in vials are provided herein. In some embodiments, an inspection tool for inspecting impurities in vials includes: a motor; a plurality of carts configured to move via the motor to selectively place each of the plurality of carts in an inspection position, wherein each of the plurality of carts includes a vial holder configured to hold a plurality of vials, and wherein each vial holder is configured to spin the plurality of vials on their own respective axes; and a camera configured to take an image of at least one of the plurality of vials of a corresponding cart of the plurality of carts when the corresponding cart is disposed in the inspection position.

公开(公告)号：US20180276811A1

公开(公告)日：2018-09-27

申请号：US15726402

申请日：2017-10-06

Applicant: Test Research, Inc.

Inventor： Kuang-Pu WEN ,  Wen-Ming WU ,  Chun-Yen HUANG

IPC: G06T7/00 ,  G01N21/95 ,  G01N21/956 ,  H04N5/247

CPC classification number: G06T7/0008 ,  G01N21/8851 ,  G01N21/9501 ,  G01N21/956 ,  G01N2021/845 ,  G01N2021/8867 ,  G01N2021/9513 ,  G01N2021/95638 ,  G01N2201/0484 ,  G06T2207/30141 ,  G06T2207/30148 ,  H04N5/247

Abstract: An automatic optical inspection system includes a first AOI machine and a second AOI machine, and the second AOI machine is electrically connected to the first AOI machine. The first AOI machine is configured to use a first resolution to inspect an object, so as to detect a possible defective region(s) of the object. The second AOI machine is configured to use a second resolution higher than the first resolution of the first AOI machine to inspect within the possible defective region(s) only, so as to detect whether there is/are any defect(s) within the possible defective region(s) of the object.

公开(公告)号：US20160299070A1

公开(公告)日：2016-10-13

申请号：US15070211

申请日：2016-03-15

Applicant: Bio-Rad Laboratories Inc.

Inventor： Yochanan URI ,  Boaz RAN ,  Ariel G. NOTCOVICH ,  Shay NIMRI

IPC: G01N21/552 ,  G01N33/543

CPC classification number: G01N21/553 ,  G01N21/253 ,  G01N21/658 ,  G01N33/54373 ,  G01N2021/0328 ,  G01N2201/0407 ,  G01N2201/0484 ,  G01N2201/062

Abstract: A tip for use in an optical detection system to analyze an analyte in a fluid sample drawn into the tip, using light reflected from a detection surface inside the tip that the analyte binds to, comprising a first detection surface and a second detection surface located in a same flow path with no controllable valve separating them, wherein the first and second detection surfaces have different surface chemistries.